Cheap Flights from Fort Myers (RSW) to Muscle Shoals (MSL)

Popular airlines from Southwest Florida Intl. Airport (RSW) to Muscle Shoals, AL (MSL-Northwest Alabama Regional)

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Cheap Flights from Fort Myers to Muscle Shoals (RSW-MSL)

Prices were available within the past 7 days and start at for one-way flights and $518 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Feb 11 - Tue, Feb 17
RSW
Fort Myers
MSL
Muscle Shoals
$518 Roundtrip, found 11 hours ago
$518
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Wed, Feb 11 from Fort Myers to Muscle Shoals, returning Tue, Feb 17, priced at $518 found 11 hours ago
United
Wed, Feb 11 - Tue, Feb 17
RSW
Fort Myers
MSL
Muscle Shoals
$533 Roundtrip, found 3 days ago
$533
Roundtrip
found 3 days ago
Select United flight, departing Wed, Feb 11 from Fort Myers to Muscle Shoals, returning Tue, Feb 17, priced at $533 found 3 days ago
American Airlines
Wed, Feb 11 - Tue, Feb 17
RSW
Fort Myers
MSL
Muscle Shoals
$572 Roundtrip, found 11 hours ago
$572
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Wed, Feb 11 from Fort Myers to Muscle Shoals, returning Tue, Feb 17, priced at $572 found 11 hours ago
United
Wed, Feb 11 - Tue, Feb 17
RSW
Fort Myers
MSL
Muscle Shoals
$587 Roundtrip, found 1 day ago
$587
Roundtrip
found 1 day ago
Select United flight, departing Wed, Feb 11 from Fort Myers to Muscle Shoals, returning Tue, Feb 17, priced at $587 found 1 day ago
American Airlines
Wed, Feb 11 - Tue, Feb 17
RSW
Fort Myers
MSL
Muscle Shoals
$626 Roundtrip, found 3 days ago
$626
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Feb 11 from Fort Myers to Muscle Shoals, returning Tue, Feb 17, priced at $626 found 3 days ago
United
Wed, Feb 11 - Tue, Feb 17
RSW
Fort Myers
MSL
Muscle Shoals
$641 Roundtrip, found 11 hours ago
$641
Roundtrip
found 11 hours ago
Select United flight, departing Wed, Feb 11 from Fort Myers to Muscle Shoals, returning Tue, Feb 17, priced at $641 found 11 hours ago

Frequently asked questions

How much does a flight from Southwest Florida Intl. Airport (RSW) to Northwest Alabama Regional Airport (MSL) cost?
Get a cheap one-way flight or cheap return flight from $518 from Southwest Florida Intl. Airport (RSW) to Northwest Alabama Regional Airport (MSL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Southwest Florida Intl. Airport (RSW) to Northwest Alabama Regional Airport (MSL)?
The cheapest month to fly from RSW to MSL is February, when demand is low. Off-peak months are generally when you'll find lower airfares between these airports.
What is the cheapest airline that flies from Southwest Florida Intl. Airport (RSW) to Northwest Alabama Regional Airport (MSL)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest RSW to MSL flight.
How many flights per day from Southwest Florida Intl. Airport (RSW) to Northwest Alabama Regional Airport (MSL)?
You'll have to book a flight with a layover when traveling from Southwest Florida Intl. Airport (RSW) to Northwest Alabama Regional Airport (MSL). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from RSW to MSL?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can change depending on a range of factors, including the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Southwest Florida Intl. Airport (RSW) to Northwest Alabama Regional Airport (MSL)?
To avoid possible delays on the Southwest Florida Intl. Airport (RSW) to Northwest Alabama Regional Airport (MSL) route, travel before 3 PM. Departures after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Southwest Florida Intl. Airport (RSW) to Northwest Alabama Regional Airport (MSL) last-minute?
Booking your flight from RSW to MSL just before your trip is typically more expensive. But if you're flexible with your travel times and dates, you could bag a cheap last-minute fare.
Is it cheaper to book a RSW to MSL flight and hotel package?
Compared with arranging hotels and flights separately, booking a RSW to MSL flight and hotel package with Expedia could lead to significant savings. What's more, having everything in one convenient place will take the stress out of planning your trip. Simply secure your flights and select from our extensive range of stays, then personalize your trip with extras like car rentals and activities.
Can I cancel or change the date of my flight from Southwest Florida Intl. Airport (RSW) to Northwest Alabama Regional Airport (MSL)?
If you booked your RSW to MSL flight in the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the fare type you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal for more details.

Travel information

Origin airport
Southwest Florida Intl.
Destination airport
Northwest Alabama Regional
Roundtrip price
$518
Distance
665 mi

Book with confidence

Fort Myers to Muscle Shoals Flights

The cheapest times to fly from Fort Myers to Muscle Shoals

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Fort Myers to Muscle Shoals are during the month of February. You can find some of the cheapest flights from Fort Myers to Muscle Shoals with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Fort Myers to Muscle Shoals

Sunday is one of the best days to book for cheap flights from Fort Myers to Muscle Shoals: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Fort Myers to Muscle Shoals

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Fort Myers to Muscle Shoals in 2026. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Fort Myers to Muscle Shoals flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Fort Myers to Muscle Shoals airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Fort Myers to Muscle Shoals Flights

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*Available to One Key members.