$782 Cheap Flights from Southampton (SOU) to Chicago (ORD)

View $782 flight on Wed, Sep 3, 2025Opens in a new window

Popular airlines from Southampton (SOU) to Chicago O'Hare Intl. Airport (ORD)

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Cheap Flights from Southampton to Chicago (SOU-ORD)

Prices were available within the past 7 days and start at $782 for one-way flights and $764 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Virgin Atlantic
Thu, Apr 23 - Mon, Apr 27
SOU
Southampton
ORD
Chicago
$764 Roundtrip, found 4 days ago
$764
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Thu, Apr 23 from Southampton to Chicago, returning Mon, Apr 27, priced at $764 found 4 days ago
Virgin Atlantic
Thu, Apr 30 - Tue, May 5
SOU
Southampton
ORD
Chicago
$781 Roundtrip, found 5 days ago
$781
Roundtrip
found 5 days ago
Select Virgin Atlantic flight, departing Thu, Apr 30 from Southampton to Chicago, returning Tue, May 5, priced at $781 found 5 days ago
Delta
Fri, Aug 29 - Fri, Sep 12
SOU
Southampton
ORD
Chicago
$809 Roundtrip, found 20 hours ago
$809
Roundtrip
found 20 hours ago
Select Delta flight, departing Fri, Aug 29 from Southampton to Chicago, returning Fri, Sep 12, priced at $809 found 20 hours ago
Virgin Atlantic
Wed, Jun 18 - Mon, Jun 23
SOU
Southampton
ORD
Chicago
$815 Roundtrip, found 4 days ago
$815
Roundtrip
found 4 days ago
Select Virgin Atlantic flight, departing Wed, Jun 18 from Southampton to Chicago, returning Mon, Jun 23, priced at $815 found 4 days ago
Delta
Wed, Jun 18 - Mon, Jun 23
SOU
Southampton
ORD
Chicago
$816 Roundtrip, found 4 days ago
$816
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, Jun 18 from Southampton to Chicago, returning Mon, Jun 23, priced at $816 found 4 days ago
Delta
Fri, Aug 29 - Fri, Sep 12
SOU
Southampton
ORD
Chicago
$819 Roundtrip, found 20 hours ago
$819
Roundtrip
found 20 hours ago
Select Delta flight, departing Fri, Aug 29 from Southampton to Chicago, returning Fri, Sep 12, priced at $819 found 20 hours ago
Virgin Atlantic
Thu, Apr 23 - Sat, May 2
SOU
Southampton
ORD
Chicago
$826 Roundtrip, found 2 days ago
$826
Roundtrip
found 2 days ago
Select Virgin Atlantic flight, departing Thu, Apr 23 from Southampton to Chicago, returning Sat, May 2, priced at $826 found 2 days ago
Delta
Wed, Jun 18 - Mon, Jun 23
SOU
Southampton
ORD
Chicago
$826 Roundtrip, found 4 days ago
$826
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, Jun 18 from Southampton to Chicago, returning Mon, Jun 23, priced at $826 found 4 days ago
KLM
Fri, Aug 29 - Fri, Sep 12
SOU
Southampton
ORD
Chicago
$847 Roundtrip, found 20 hours ago
$847
Roundtrip
found 20 hours ago
Select KLM flight, departing Fri, Aug 29 from Southampton to Chicago, returning Fri, Sep 12, priced at $847 found 20 hours ago
Aer Lingus
Thu, Apr 23 - Mon, Apr 27
SOU
Southampton
ORD
Chicago
$861 Roundtrip, found 4 days ago
$861
Roundtrip
found 4 days ago
Select Aer Lingus flight, departing Thu, Apr 23 from Southampton to Chicago, returning Mon, Apr 27, priced at $861 found 4 days ago
Flights from Southampton (SOU) to Chicago (ORD)
Origin airport
Southampton
Destination airport
O'Hare Intl.
Airlines serving
Aer Lingus, Delta, KLM, Virgin Atlantic
Roundtrip price
$764
Distance
3923 mi

Southampton to Chicago Flights

The cheapest times to fly from Southampton to Chicago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Southampton to Chicago are during the month of April. You can find some of the cheapest flights from Southampton to Chicago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Southampton to Chicago

Sunday is one of the best days to book for cheap flights from Southampton to Chicago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Southampton to Chicago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Southampton to Chicago in 2025. You can also book with separate airlines for your outbound and return journeys, from $782 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Southampton to Chicago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Southampton to Chicago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Southampton Airport (SOU) to O'Hare Intl. Airport (ORD) cost?
Discover the latest flight deals from SOU to ORD by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from SOU to ORD?
The cheapest flights from SOU to ORD are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Southampton Airport (SOU) to O'Hare Intl. Airport (ORD)?
While Southampton (SOU) has no direct flights to O’Hare Intl. Airport (ORD), other airports have nonstop options. Leaving from Heathrow Airport (LHR) will get you to Chicago without any detours.
What is the cheapest airline that flies from SOU to ORD?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that’ll take you from SOU to ORD. Sort your results by “Price (lowest to highest)” to snap up a great deal.
How many flights per day from Southampton Airport (SOU) to O'Hare Intl. Airport (ORD)?
You’ll have to hop on a flight with a layover if you’re traveling from Southampton Airport (SOU) to O’Hare Intl. Airport (ORD). There are no daily direct flights on this route. However, just filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from SOU to ORD?
Generally you’ll find the greatest selection of flight options on a Friday. Tuesdays tend to be the quietest.* But this can vary based on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Southampton Airport (SOU) to O'Hare Intl. Airport (ORD)?
Opt for a flight from Southampton Airport (SOU) to O’Hare Intl. Airport (ORD) that takes off before 3 PM to reduce the risk of cancellations. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.
Is it cheaper to buy a plane ticket from Southampton Airport (SOU) to O'Hare Intl. Airport (ORD) last-minute?
Waiting until right before your break to book a flight from SOU to ORD generally means paying more. Although you may find some last-minute discounts, they’re not always guaranteed. Keep your travel schedule open to boost your chances of getting a bargain.
Is it cheaper to book a SOU to ORD flight and hotel package?
Opting for a SOU to ORD flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels in one place. Choose from our extensive range of accommodations and then add activities, car rentals and flights to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Southampton Airport (SOU) to O'Hare Intl. Airport (ORD)?
If you booked your SOU to ORD flight within the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the ticket type you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for more details.

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*Available to One Key members.