Cheap Flights from St. Louis (STL) to Muscle Shoals (MSL)

Popular airlines from St. Louis Lambert Intl. Airport (STL) to Muscle Shoals, AL (MSL-Northwest Alabama Regional)

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Cheap Flights from St. Louis to Muscle Shoals (STL-MSL)

Prices were available within the past 7 days and start at for one-way flights and $450 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, Oct 18 - Sun, Oct 19
STL
St. Louis
MSL
Muscle Shoals
$450 Roundtrip, found 4 days ago
$450
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Oct 18 from St. Louis to Muscle Shoals, returning Sun, Oct 19, priced at $450 found 4 days ago
American Airlines
Sat, Oct 18 - Sun, Oct 19
STL
St. Louis
MSL
Muscle Shoals
$495 Roundtrip, found 4 days ago
$495
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Oct 18 from St. Louis to Muscle Shoals, returning Sun, Oct 19, priced at $495 found 4 days ago
American Airlines
Sat, Oct 18 - Sun, Oct 19
STL
St. Louis
MSL
Muscle Shoals
$539 Roundtrip, found 4 days ago
$539
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Oct 18 from St. Louis to Muscle Shoals, returning Sun, Oct 19, priced at $539 found 4 days ago
American Airlines
Sat, Oct 18 - Sun, Oct 19
STL
St. Louis
MSL
Muscle Shoals
$572 Roundtrip, found 4 days ago
$572
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Oct 18 from St. Louis to Muscle Shoals, returning Sun, Oct 19, priced at $572 found 4 days ago
American Airlines
Mon, Oct 13 - Thu, Oct 16
STL
St. Louis
MSL
Muscle Shoals
$692 Roundtrip, found 13 hours ago
$692
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Mon, Oct 13 from St. Louis to Muscle Shoals, returning Thu, Oct 16, priced at $692 found 13 hours ago
American Airlines
Mon, Oct 13 - Thu, Oct 16
STL
St. Louis
MSL
Muscle Shoals
$726 Roundtrip, found 13 hours ago
$726
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Mon, Oct 13 from St. Louis to Muscle Shoals, returning Thu, Oct 16, priced at $726 found 13 hours ago
American Airlines
Mon, Oct 13 - Thu, Oct 16
STL
St. Louis
MSL
Muscle Shoals
$739 Roundtrip, found 13 hours ago
$739
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Mon, Oct 13 from St. Louis to Muscle Shoals, returning Thu, Oct 16, priced at $739 found 13 hours ago
United
Mon, Oct 13 - Thu, Oct 16
STL
St. Louis
MSL
Muscle Shoals
$2,535 Roundtrip, found 13 hours ago
$2,535
Roundtrip
found 13 hours ago
Select United flight, departing Mon, Oct 13 from St. Louis to Muscle Shoals, returning Thu, Oct 16, priced at $2,535 found 13 hours ago

Frequently asked questions

How much does a flight from Lambert-St. Louis Intl. Airport (STL) to Northwest Alabama Regional Airport (MSL) cost?
Get a cheap one-way flight or cheap return flight from $450 from Lambert-St. Louis Intl. Airport (STL) to Northwest Alabama Regional Airport (MSL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Lambert-St. Louis Intl. Airport (STL) to Northwest Alabama Regional Airport (MSL)?
October is the cheapest month to fly from STL to MSL. Timing your trip outside of the busy season is often the key to finding better deals on flights.
What is the cheapest airline that flies from Lambert-St. Louis Intl. Airport (STL) to Northwest Alabama Regional Airport (MSL)?
Use the filters on Expedia to compare different airlines and find the most affordable carrier that'll fly you from STL to MSL. Then, sort your results by "Price (lowest to highest)" to score the best deal available.
How many flights per day from Lambert-St. Louis Intl. Airport (STL) to Northwest Alabama Regional Airport (MSL)?
There are no daily nonstop flights available from Lambert-St. Louis Intl. Airport (STL) to Northwest Alabama Regional Airport (MSL). But you can opt for flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be cruising above the clouds in no time.
What day of the week has the most flights from STL to MSL?
Generally you'll find the widest variety of flight choices on a Friday. Tuesdays are often the quietest.* However, this can vary based on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Lambert-St. Louis Intl. Airport (STL) to Northwest Alabama Regional Airport (MSL)?
To arrive at Northwest Alabama Regional Airport (MSL) on schedule, book a flight that leaves from Lambert-St. Louis Intl. Airport (STL) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Lambert-St. Louis Intl. Airport (STL) to Northwest Alabama Regional Airport (MSL) last-minute?
Booking your ticket from STL to MSL just before your getaway is usually more expensive. However, if there's some wiggle room with your departure times and dates, you could grab a cheap last-minute fare.
Is it cheaper to book a STL to MSL flight and hotel package?
Booking a STL to MSL flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Select from our extensive range of stays and then add car rentals, activities and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Lambert-St. Louis Intl. Airport (STL) to Northwest Alabama Regional Airport (MSL)?
If you booked your STL to MSL flight within the last 24 hours, you may be able to modify or cancel it at no cost. Depending on the airline and the type of fare you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you want more information.

Travel information

Origin airport
Lambert-St. Louis Intl.
Destination airport
Northwest Alabama Regional
Roundtrip price
$450
Distance
315 mi

Book with confidence

St. Louis to Muscle Shoals Flights

The cheapest times to fly from St. Louis to Muscle Shoals

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to Muscle Shoals are during the month of October. You can find some of the cheapest flights from St. Louis to Muscle Shoals with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to Muscle Shoals

Sunday is one of the best days to book for cheap flights from St. Louis to Muscle Shoals: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to Muscle Shoals

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to Muscle Shoals in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to Muscle Shoals flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to Muscle Shoals airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

St. Louis to Muscle Shoals Flights

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*Available to One Key members.