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$269 Cheap Flights from St. Louis (STL) to Syracuse (SYR)

View $269 flight on Wed, Dec 16, 2026Opens in a new window

Popular airlines from St. Louis Lambert Intl. Airport (STL) to Hancock Intl. Airport (SYR)

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Cheap Flights from St. Louis to Syracuse (STL-SYR)

Prices were available within the past 7 days and start at $269 for one-way flights and $301 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Oct 7 - Tue, Oct 20
STL
St. Louis
SYR
Syracuse
$301 Roundtrip, found 2 hours ago
$301
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Wed, Oct 7 from St. Louis to Syracuse, returning Tue, Oct 20, priced at $301 found 2 hours ago
United
Wed, Oct 7 - Tue, Oct 20
STL
St. Louis
SYR
Syracuse
$301 Roundtrip, found 2 hours ago
$301
Roundtrip
found 2 hours ago
Select United flight, departing Wed, Oct 7 from St. Louis to Syracuse, returning Tue, Oct 20, priced at $301 found 2 hours ago
United
Sat, Oct 17 - Sat, Oct 24
STL
St. Louis
SYR
Syracuse
$306 Roundtrip, found 5 hours ago
$306
Roundtrip
found 5 hours ago
Select United flight, departing Sat, Oct 17 from St. Louis to Syracuse, returning Sat, Oct 24, priced at $306 found 5 hours ago
American Airlines
Wed, Oct 7 - Tue, Oct 20
STL
St. Louis
SYR
Syracuse
$310 Roundtrip, found 2 hours ago
$310
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Wed, Oct 7 from St. Louis to Syracuse, returning Tue, Oct 20, priced at $310 found 2 hours ago
United
Sat, Oct 17 - Sat, Oct 24
STL
St. Louis
SYR
Syracuse
$314 Roundtrip, found 5 hours ago
$314
Roundtrip
found 5 hours ago
Select United flight, departing Sat, Oct 17 from St. Louis to Syracuse, returning Sat, Oct 24, priced at $314 found 5 hours ago
United
Sun, Nov 1 - Sat, Nov 14
STL
St. Louis
SYR
Syracuse
$315 Roundtrip, found 5 hours ago
$315
Roundtrip
found 5 hours ago
Select United flight, departing Sun, Nov 1 from St. Louis to Syracuse, returning Sat, Nov 14, priced at $315 found 5 hours ago
United
Fri, Mar 5 - Sun, Mar 7
STL
St. Louis
SYR
Syracuse
$319 Roundtrip, just found
$319
Roundtrip
just found
Select United flight, departing Fri, Mar 5 from St. Louis to Syracuse, returning Sun, Mar 7, priced at $319 just found
United
Sat, Oct 3 - Sat, Oct 10
STL
St. Louis
SYR
Syracuse
$319 Roundtrip, found 5 hours ago
$319
Roundtrip
found 5 hours ago
Select United flight, departing Sat, Oct 3 from St. Louis to Syracuse, returning Sat, Oct 10, priced at $319 found 5 hours ago
Delta
Wed, Oct 7 - Tue, Oct 20
STL
St. Louis
SYR
Syracuse
$321 Roundtrip, found 2 hours ago
$321
Roundtrip
found 2 hours ago
Select Delta flight, departing Wed, Oct 7 from St. Louis to Syracuse, returning Tue, Oct 20, priced at $321 found 2 hours ago
United
Sat, Sep 26 - Wed, Sep 30
STL
St. Louis
SYR
Syracuse
$324 Roundtrip, found 1 day ago
$324
Roundtrip
found 1 day ago
Select United flight, departing Sat, Sep 26 from St. Louis to Syracuse, returning Wed, Sep 30, priced at $324 found 1 day ago

Alternative airports near Syracuse

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Hancock Intl. SYR. Cheapest and Closest option available. Average driving time to city center is 9 minutes. Flights from $414
SYR
Hancock Intl.
CheapestClosest
Average driving time to city center9 min
Flights from $414

What you need to know for your flight from Lambert-St. Louis Intl. to Hancock Intl.

St. Louis (STL) to Syracuse (SYR) at a glance

Explore a range of airlines operating flights from St. Louis (STL) to Syracuse (SYR) on this domestic short-haul route. Compare options between full-service and low-cost carriers to discover the itinerary that aligns with your budget, schedule, and travel plans while you experience the renowned attractions and neighborhoods of Syracuse. Find essential information for flights departing from Lambert-St. Louis International Airport (STL) to Hancock International Airport (SYR).

  • Fastest flight duration: around 3h 30m in-flight, plus roughly 1h 15m layover with one stop
  • Route distance: roughly 800 miles (1,290 km)
  • Flights per week: around 11 departures on average
  • Typical fares (one-way): economy tickets often range from $120–$440, depending on seasonality and how far ahead you book

Flights from Lambert-St. Louis International Airport (STL) to Hancock International Airport (SYR)

Based on the latest traveler bookings, here are the top airlines favored for flights from St. Louis to Syracuse, especially for one-stop services. Notable layover options include Detroit Metropolitan Wayne County Airport (DTW) with a layover of about 1 hour and 15 minutes, O'Hare International Airport (ORD) also around 1 hour and 15 minutes, and Ronald Reagan Washington National Airport (DCA) with a layover of approximately 1 hour. These choices allow you to tailor your travel experience by balancing price, overall travel time, and cabin class to secure the ideal itinerary.

  • American Airlines: This full-service airline provides one-stop travel options, with one-way ticket prices generally falling between $120 and $435. It represents about 47% of flights on this route, featuring an in-air duration of 3 hours and 30 minutes, leading to a total travel time of approximately 4 hours and 45 minutes, including layover time.
  • Delta: As another full-service airline, Delta offers one-stop flights with one-way fares typically ranging from $120 to $450. It handles around 40% of the departures on this route, with an in-flight duration of 3 hours and 30 minutes, resulting in a total journey time of about 4 hours and 45 minutes, factoring in the layover.
  • United: This full-service carrier also provides one-stop services, with one-way fares generally spanning from $125 to $485. United accounts for approximately 12% of departures on this route, featuring an in-flight time of 3 hours and 30 minutes, and a total travel time of roughly 4 hours and 45 minutes, including layover considerations.

Travelers flying from St. Louis to Syracuse can elevate their journey with upgraded options. Delta provides both first class and premium economy cabins, while American Airlines exclusively offers first class service for a more comfortable flight experience.

Best time to fly from St. Louis (STL) to Syracuse (SYR)

The most popular months for travelers flying from St. Louis to Syracuse are March, May, and July, when peak temperatures in Syracuse reach up to 70.5°F in July. If you prefer quieter travel, consider December, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 31.3°F. For better deals, August usually offers the lowest average one-way fare around $205. Flight availability peaks in May, July, and August, with approximately 12 flights per week, making it easier to find convenient departure times. April has the fewest flights, with approximately 8 flights per week.

  • Cheapest time to fly: August usually offers good deals with average one-way fare around $205, roughly 14% cheaper than the yearly average.
  • More budget-friendly months to fly: July, December, and February typically offer average one-way fares roughly ranging from $206 to $223.
  • Most flight options: May, July, and August have the highest number of flights from St. Louis to Syracuse, with approximately 12 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January23.9°F (-4.5°C)Average10$227
February25.3°F (-3.7°C)Average9$223
March33.3°F (0.7°C)Slightly High11$280
April45.0°F (7.2°C)Average8$277
May57.4°F (14.1°C)Slightly High12$236
June64.8°F (18.2°C)Average11$232
July70.5°F (21.4°C)Slightly High12$206
August68.9°F (20.5°C)Average12$205
September62.4°F (16.9°C)Average11$243
October51.8°F (11.0°C)Slightly Low11$254
November39.6°F (4.2°C)Slightly Low11$277
December31.3°F (-0.4°C)Slightly Low11$211

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative routes from St. Louis (STL) to Syracuse (SYR)

  • St. Louis to Syracuse (SUS-SYR): Spirit of St. Louis Airport (SUS) is located approximately 16 miles from Lambert-St. Louis International Airport (STL).
  • St. Louis to Rome (STL-RME): Griffiss International Airport (RME) lies about 36 miles from Hancock International Airport (SYR).
  • St. Louis to Rome (SUS-RME): Spirit of St. Louis Airport (SUS) is roughly 16 miles from Lambert-St. Louis International Airport (STL), while Griffiss International Airport (RME) is around 36 miles from Hancock International Airport (SYR).

How to find the best prices for flights from St. Louis (STL) to Syracuse (SYR)

Getting some of the best deals on flights from St. Louis to Syracuse is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are typically found when booking 2-8 weeks in advance, which coincides with when most travelers make their reservations. Morning departures (5 am-12 pm) often offer lower prices and are also the most popular flight times. Additionally, flying on Tuesday usually provides cheaper rates, while Friday remains the most popular travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Hancock International Airport from Lambert-St. Louis International Airport

Syracuse welcomes travelers from St. Louis with a range of transport options based on price, convenience, and proximity. Syracuse city center is approximately a 10-minute drive (covering about 8 miles) from Hancock International Airport, depending on traffic. Here's how to reach Syracuse efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Syracuse, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Hancock International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Hancock International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Hancock International Airport, the Syracuse Airport Bus Stop, a bus station, is just about 0.1 miles away on foot, while the Syracuse Regional Transportation Center, a train station, is approximately 5.8 miles away by car. Additionally, the Syracuse Seaport, a seaport, is located around 8.4 miles away by car.

Frequently asked questions

How much does a flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.) cost?
You can find cheap one-way flights from $269 and cheap return flights from $301 St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.) with Expedia. One-way flights usually range from $238 to $704, and return flights typically cost between $364 and $1111. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.)?
January is the cheapest month to fly from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.), with average round-trip fares around $333. This price is about 16% lower than the average throughout the year, as travel demand tends to decrease after the holiday season. Other affordable months to consider are April and September.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.)?
Enter STL to SYR and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.)?
Frontier Airlines is one of the cheapest airlines offering connecting flights from St. Louis, MO (STL) to Syracuse, NY (SYR), with round-trip tickets starting from around $226. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.)?
To find a cheap flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.)?
For your trip from St. Louis (STL) to Syracuse (SYR), January and April are the best months to fly. Average return flight prices are around $333. January is often quieter, while April brings the beauty of spring, making both months appealing for travel.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.)?
Sort flights by "Departure (earliest)" on Expedia to find the earliest flight from STL to SYR. To compare more early flights, use the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.)?
The most popular departure times for flights from St. Louis (STL) to Syracuse (SYR) are in the early morning, from 6am to 9am. About 38% of passengers prefer this time window. Many major carriers, including American Airlines, Delta, and United, offer flights during this window. This timing works well because it allows you to start your day early and arrive in Syracuse with plenty of time to enjoy your day.
How long does it take to fly from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.)?
Flying from STL to SYR with a connection usually takes about 4 hours 50 minutes, traveling roughly 802 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.)?
You can fly first class between STL and SYR. First class cabins are available on:

  • American Airlines
  • United Airlines
  • Delta Air Lines

How do I earn miles on a St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.) flight with Expedia?
It's easy to earn miles on a St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Syracuse from Lambert-St. Louis Intl. (STL)?
From Lambert-St. Louis Intl. (STL), you can fly into Hancock Intl. (SYR) to reach Syracuse. Some flights may connect through major hubs like O'Hare Intl. (ORD), LaGuardia (LGA), Hartsfield-Jackson Atlanta Intl. (ATL) before reaching Syracuse. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.) at the last minute?
Typically, booking a last minute flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.) flight and hotel package?
Securing a St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.)?
If you booked your St. Louis, MO (STL-Lambert-St. Louis Intl.) to Syracuse, NY (SYR-Hancock Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Lambert-St. Louis Intl.
Destination airport
Hancock Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$300
Distance
801 mi

Book with confidence

St. Louis to Syracuse Flights

The cheapest times to fly from St. Louis to Syracuse

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to Syracuse are during the month of October. You can find some of the cheapest flights from St. Louis to Syracuse with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to Syracuse

Sunday is one of the best days to book for cheap flights from St. Louis to Syracuse: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to Syracuse

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to Syracuse in 2026. You can also book with separate airlines for your outbound and return journeys, from $269 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to Syracuse flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to Syracuse airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

St. Louis to Syracuse Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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