$128 Cheap Flights from Syracuse (SYR) to Key West (EYW)

View $128 flight on Sun, Dec 14, 2025Opens in a new window

Popular airlines from Hancock Intl. Airport (SYR) to Key West Intl. Airport (EYW)

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Cheap Flights from Syracuse to Key West (SYR-EYW)

Prices were available within the past 7 days and start at $128 for one-way flights and $255 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Sun, Dec 7 - Thu, Dec 25
SYR
Syracuse
EYW
Key West
$255 Roundtrip, found 9 hours ago
$255
Roundtrip
found 9 hours ago
Select JetBlue Airways flight, departing Sun, Dec 7 from Syracuse to Key West, returning Thu, Dec 25, priced at $255 found 9 hours ago
JetBlue Airways
Sun, Dec 14 - Wed, Dec 17
SYR
Syracuse
EYW
Key West
$267 Roundtrip, just found
$267
Roundtrip
just found
Select JetBlue Airways flight, departing Sun, Dec 14 from Syracuse to Key West, returning Wed, Dec 17, priced at $267 just found
JetBlue Airways
Tue, Jan 20 - Wed, Jan 21
SYR
Syracuse
EYW
Key West
$268 Roundtrip, found 2 days ago
$268
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Tue, Jan 20 from Syracuse to Key West, returning Wed, Jan 21, priced at $268 found 2 days ago
American Airlines
Thu, Dec 11 - Thu, Dec 18
SYR
Syracuse
EYW
Key West
$269 Roundtrip, found 11 hours ago
$269
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Thu, Dec 11 from Syracuse to Key West, returning Thu, Dec 18, priced at $269 found 11 hours ago
Delta
Tue, Apr 21 - Wed, May 6
SYR
Syracuse
EYW
Key West
$269 Roundtrip, found 8 hours ago
$269
Roundtrip
found 8 hours ago
Select Delta flight, departing Tue, Apr 21 from Syracuse to Key West, returning Wed, May 6, priced at $269 found 8 hours ago
JetBlue Airways
Mon, Jan 19 - Fri, Jan 23
SYR
Syracuse
EYW
Key West
$270 Roundtrip, found 1 day ago
$270
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Mon, Jan 19 from Syracuse to Key West, returning Fri, Jan 23, priced at $270 found 1 day ago
JetBlue Airways
Wed, Jan 14 - Sat, Jan 24
SYR
Syracuse
EYW
Key West
$272 Roundtrip, found 2 hours ago
$272
Roundtrip
found 2 hours ago
Select JetBlue Airways flight, departing Wed, Jan 14 from Syracuse to Key West, returning Sat, Jan 24, priced at $272 found 2 hours ago
American Airlines
Mon, Jan 5 - Thu, Jan 8
SYR
Syracuse
EYW
Key West
$274 Roundtrip, found 4 days ago
$274
Roundtrip
found 4 days ago
Select American Airlines flight, departing Mon, Jan 5 from Syracuse to Key West, returning Thu, Jan 8, priced at $274 found 4 days ago
American Airlines
Wed, Jan 14 - Sat, Jan 24
SYR
Syracuse
EYW
Key West
$274 Roundtrip, found 2 hours ago
$274
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Wed, Jan 14 from Syracuse to Key West, returning Sat, Jan 24, priced at $274 found 2 hours ago
United
Tue, Dec 16 - Sun, Dec 21
SYR
Syracuse
EYW
Key West
$338 Roundtrip, found 2 days ago
$338
Roundtrip
found 2 days ago
Select United flight, departing Tue, Dec 16 from Syracuse to Key West, returning Sun, Dec 21, priced at $338 found 2 days ago

Find the cheapest month to fly from Syracuse (SYR) to Key West (EYW)

November is typically the cheapest month to fly

From $209 - $730 per traveler.

Alternative airports near Key West

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Key West Intl. EYW. Cheapest and Closest option available. Average driving time to city center is 8 minutes. Flights from $439
EYW
Key West Intl.
CheapestClosest
Average driving time to city center8 min
Flights from $439

Frequently asked questions

How much does a flight from Hancock Intl. Airport (SYR) to Key West Intl. Airport (EYW) cost?
Secure a cheap one-way flight from $128 or cheap return flight from $255 from Hancock Intl. Airport (SYR) to Key West Intl. Airport (EYW) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Hancock Intl. Airport (SYR) to Key West Intl. Airport (EYW)?
Traveling in December is a good way to save, as it's the cheapest month for flights between SYR and EYW. You'll often find the lowest fares during off-peak months.
What is the cheapest airline that flies from Hancock Intl. Airport (SYR) to Key West Intl. Airport (EYW)?
To find the cheapest airline that'll fly you from SYR to EYW, use Expedia's filter tool. Tailor your search based on what's important to you, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from Hancock Intl. Airport (SYR) to Key West Intl. Airport (EYW)?
You'll have to book a flight with a layover when traveling from Hancock Intl. Airport (SYR) to Key West Intl. Airport (EYW). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to discover the best option for your trip.
What day of the week has the most flights from SYR to EYW?
Generally you'll find the most flight options available on a Friday. Tuesdays are often the quietest.* But this can change depending on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Hancock Intl. Airport (SYR) to Key West Intl. Airport (EYW)?
To arrive at Key West Intl. Airport (EYW) on schedule, pick a flight that takes off from Hancock Intl. Airport (SYR) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Hancock Intl. Airport (SYR) to Key West Intl. Airport (EYW) last-minute?
Last-minute bookings from SYR to EYW are usually more expensive. To secure the lowest rates, start searching for flights well in advance. That being said, if you're flexible with your travel plans, it's possible to land a cheap fare right before you leave.
Is it cheaper to book a SYR to EYW flight and hotel package?
You'll typically save money by securing a SYR to EYW flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one convenient place. After selecting your preferred accommodations and flights, you can add extras like car rentals, tours and activities.
Can I cancel or change the date of my flight from Hancock Intl. Airport (SYR) to Key West Intl. Airport (EYW)?
If you reserved your SYR to EYW flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you want more information.

Travel information

Origin airport
Hancock Intl.
Destination airport
Key West Intl.
Airlines serving
American Airlines, Delta, JetBlue Airways, United
Roundtrip price
$254
Distance
1321 mi

Book with confidence

Syracuse to Key West Flights

The cheapest times to fly from Syracuse to Key West

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Syracuse to Key West are during the month of December. You can find some of the cheapest flights from Syracuse to Key West with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Syracuse to Key West

Sunday is one of the best days to book for cheap flights from Syracuse to Key West: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Syracuse to Key West

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Syracuse to Key West in 2025. You can also book with separate airlines for your outbound and return journeys, from $128 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Syracuse to Key West flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Syracuse to Key West airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Syracuse to Key West Flights

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*Available to One Key members.