$122 Cheap Flights from Syracuse (SYR) to Key West (EYW)

View $122 flight on Fri, Oct 24, 2025Opens in a new window

Popular airlines from Hancock Intl. Airport (SYR) to Key West Intl. Airport (EYW)

Cheap Flights from Syracuse to Key West (SYR-EYW)

Prices were available within the past 7 days and start at $122 for one-way flights and $223 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Mon, Oct 20 - Fri, Oct 24
SYR
Syracuse
EYW
Key West
$223 Roundtrip, found 4 days ago
$223
Roundtrip
found 4 days ago
Select JetBlue Airways flight, departing Mon, Oct 20 from Syracuse to Key West, returning Fri, Oct 24, priced at $223 found 4 days ago
JetBlue Airways
Mon, Oct 27 - Sat, Nov 1
SYR
Syracuse
EYW
Key West
$242 Roundtrip, found 2 hours ago
$242
Roundtrip
found 2 hours ago
Select JetBlue Airways flight, departing Mon, Oct 27 from Syracuse to Key West, returning Sat, Nov 1, priced at $242 found 2 hours ago
JetBlue Airways
Fri, Oct 31 - Sat, Nov 1
SYR
Syracuse
EYW
Key West
$262 Roundtrip, found 2 hours ago
$262
Roundtrip
found 2 hours ago
Select JetBlue Airways flight, departing Fri, Oct 31 from Syracuse to Key West, returning Sat, Nov 1, priced at $262 found 2 hours ago
JetBlue Airways
Sun, Oct 26 - Sat, Nov 1
SYR
Syracuse
EYW
Key West
$264 Roundtrip, found 2 hours ago
$264
Roundtrip
found 2 hours ago
Select JetBlue Airways flight, departing Sun, Oct 26 from Syracuse to Key West, returning Sat, Nov 1, priced at $264 found 2 hours ago
Delta
Tue, Oct 28 - Sat, Nov 1
SYR
Syracuse
EYW
Key West
$269 Roundtrip, found 2 hours ago
$269
Roundtrip
found 2 hours ago
Select Delta flight, departing Tue, Oct 28 from Syracuse to Key West, returning Sat, Nov 1, priced at $269 found 2 hours ago
United
Tue, Oct 28 - Tue, Nov 4
SYR
Syracuse
EYW
Key West
$269 Roundtrip, found 2 hours ago
$269
Roundtrip
found 2 hours ago
Select United flight, departing Tue, Oct 28 from Syracuse to Key West, returning Tue, Nov 4, priced at $269 found 2 hours ago
American Airlines
Tue, Oct 28 - Tue, Nov 4
SYR
Syracuse
EYW
Key West
$269 Roundtrip, found 2 hours ago
$269
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Tue, Oct 28 from Syracuse to Key West, returning Tue, Nov 4, priced at $269 found 2 hours ago
United
Fri, Jan 23 - Thu, Feb 5
SYR
Syracuse
EYW
Key West
$274 Roundtrip, found 3 hours ago
$274
Roundtrip
found 3 hours ago
Select United flight, departing Fri, Jan 23 from Syracuse to Key West, returning Thu, Feb 5, priced at $274 found 3 hours ago
American Airlines
Sat, Dec 6 - Wed, Dec 10
SYR
Syracuse
EYW
Key West
$276 Roundtrip, just found
$276
Roundtrip
just found
Select American Airlines flight, departing Sat, Dec 6 from Syracuse to Key West, returning Wed, Dec 10, priced at $276 just found
Delta
Fri, Jan 2 - Tue, Jan 13
SYR
Syracuse
EYW
Key West
$279 Roundtrip, found 19 hours ago
$279
Roundtrip
found 19 hours ago
Select Delta flight, departing Fri, Jan 2 from Syracuse to Key West, returning Tue, Jan 13, priced at $279 found 19 hours ago

Find the cheapest month to fly from Syracuse (SYR) to Key West (EYW)

November is typically the cheapest month to fly

From $201 - $712 per traveler.

Graph displaying average flight prices per month

Alternative airports near Key West

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Key West Intl. EYW. Cheapest and Closest option available. Average driving time to city center is 8 minutes. Flights from $294
EYW
Key West Intl.
CheapestClosest
Average driving time to city center8 min
Flights from $294
Flights from Syracuse (SYR) to Key West (EYW)
Origin airport
Hancock Intl.
Destination airport
Key West Intl.
Airlines serving
American Airlines, Delta, JetBlue Airways, United
Roundtrip price
$222
Distance
1321 mi

Syracuse to Key West Flights

The cheapest times to fly from Syracuse to Key West

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Syracuse to Key West are during the month of October. You can find some of the cheapest flights from Syracuse to Key West with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Syracuse to Key West

Sunday is one of the best days to book for cheap flights from Syracuse to Key West: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Syracuse to Key West

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Syracuse to Key West in 2025. You can also book with separate airlines for your outbound and return journeys, from $122 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Syracuse to Key West flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Syracuse to Key West airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Hancock Intl. Airport (SYR) to Key West Intl. Airport (EYW) cost?
Discover the latest flight deals from SYR to EYW by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from SYR to EYW?
The cheapest flights from SYR to EYW are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from SYR to EYW?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from SYR to EYW. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Hancock Intl. Airport (SYR) to Key West Intl. Airport (EYW)?
You'll have to book a flight with a layover when traveling from Hancock Intl. Airport (SYR) to Key West Intl. Airport (EYW). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to discover the best option for your trip.
What day of the week has the most flights from SYR to EYW?
Generally you'll find the most flight options available on a Friday. Tuesdays are often the quietest.* But this can change depending on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Hancock Intl. Airport (SYR) to Key West Intl. Airport (EYW)?
To arrive at Key West Intl. Airport (EYW) on schedule, pick a flight that takes off from Hancock Intl. Airport (SYR) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Hancock Intl. Airport (SYR) to Key West Intl. Airport (EYW) last-minute?
Last-minute bookings from SYR to EYW are usually more expensive. To secure the lowest rates, start searching for flights well in advance. That being said, if you're flexible with your travel plans, it's possible to land a cheap fare right before you leave.
Is it cheaper to book a SYR to EYW flight and hotel package?
You'll typically save money by securing a SYR to EYW flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one convenient place. After selecting your preferred accommodations and flights, you can add extras like car rentals, tours and activities.
Can I cancel or change the date of my flight from Hancock Intl. Airport (SYR) to Key West Intl. Airport (EYW)?
If you reserved your SYR to EYW flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you want more information.

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*Available to One Key members.