$434 Cheap Flights from Syracuse (SYR) to Santiago (SCL)

View $434 flight on Tue, Oct 21, 2025Opens in a new window

Popular airlines from Hancock Intl. Airport (SYR) to Santiago Intl. Airport (SCL)

Cheap Flights from Syracuse to Santiago (SYR-SCL)

Prices were available within the past 7 days and start at $434 for one-way flights and $784 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, Oct 15 - Mon, Oct 20
SYR
Syracuse
SCL
Santiago
$784 Roundtrip, found 6 days ago
$784
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, Oct 15 from Syracuse to Santiago, returning Mon, Oct 20, priced at $784 found 6 days ago
American Airlines
Wed, Oct 15 - Mon, Oct 20
SYR
Syracuse
SCL
Santiago
$788 Roundtrip, found 6 days ago
$788
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Oct 15 from Syracuse to Santiago, returning Mon, Oct 20, priced at $788 found 6 days ago
Delta
Wed, Oct 15 - Mon, Oct 20
SYR
Syracuse
SCL
Santiago
$803 Roundtrip, found 6 days ago
$803
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, Oct 15 from Syracuse to Santiago, returning Mon, Oct 20, priced at $803 found 6 days ago
LATAM Airlines Group
Thu, Oct 30 - Tue, Nov 4
SYR
Syracuse
SCL
Santiago
$804 Roundtrip, found 3 days ago
$804
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Thu, Oct 30 from Syracuse to Santiago, returning Tue, Nov 4, priced at $804 found 3 days ago
United
Mon, Feb 16 - Mon, Mar 2
SYR
Syracuse
SCL
Santiago
$808 Roundtrip, found 17 hours ago
$808
Roundtrip
found 17 hours ago
Select United flight, departing Mon, Feb 16 from Syracuse to Santiago, returning Mon, Mar 2, priced at $808 found 17 hours ago
LATAM Airlines Group
Tue, Oct 21 - Tue, Oct 28
SYR
Syracuse
SCL
Santiago
$810 Roundtrip, found 3 days ago
$810
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Tue, Oct 21 from Syracuse to Santiago, returning Tue, Oct 28, priced at $810 found 3 days ago
LATAM Airlines Group
Thu, Oct 30 - Tue, Nov 4
SYR
Syracuse
SCL
Santiago
$813 Roundtrip, found 3 days ago
$813
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Thu, Oct 30 from Syracuse to Santiago, returning Tue, Nov 4, priced at $813 found 3 days ago
LATAM Airlines Group
Tue, Oct 21 - Tue, Oct 28
SYR
Syracuse
SCL
Santiago
$813 Roundtrip, found 3 days ago
$813
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Tue, Oct 21 from Syracuse to Santiago, returning Tue, Oct 28, priced at $813 found 3 days ago
LATAM Airlines Group
Tue, Oct 21 - Tue, Oct 28
SYR
Syracuse
SCL
Santiago
$815 Roundtrip, found 3 days ago
$815
Roundtrip
found 3 days ago
Select LATAM Airlines Group flight, departing Tue, Oct 21 from Syracuse to Santiago, returning Tue, Oct 28, priced at $815 found 3 days ago
JetBlue Airways
Mon, Mar 16 - Sun, Apr 5
SYR
Syracuse
SCL
Santiago
$824 Roundtrip, found 17 hours ago
$824
Roundtrip
found 17 hours ago
Select JetBlue Airways flight, departing Mon, Mar 16 from Syracuse to Santiago, returning Sun, Apr 5, priced at $824 found 17 hours ago

Alternative airports near Santiago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Arturo Merino Benitez SCL. Cheapest and Closest option available. Average driving time to city center is 17 minutes. Flights from $1,048
SCL
Arturo Merino Benitez
CheapestClosest
Average driving time to city center17 min
Flights from $1,048
Flights from Syracuse (SYR) to Santiago (SCL)
Origin airport
Hancock Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Air Canada, American Airlines, Delta, LATAM Airlines Group, United
Roundtrip price
$783
Distance
5296 mi

Syracuse to Santiago Flights

The cheapest times to fly from Syracuse to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Syracuse to Santiago are during the month of October. You can find some of the cheapest flights from Syracuse to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Syracuse to Santiago

Sunday is one of the best days to book for cheap flights from Syracuse to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Syracuse to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Syracuse to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $434 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Syracuse to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Syracuse to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Hancock Intl. Airport (SYR) to Arturo Merino Benitez Airport (SCL) cost?
Secure a cheap one-way flight from $434 or cheap return flight from $784 from Hancock Intl. Airport (SYR) to Arturo Merino Benitez Airport (SCL) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Hancock Intl. Airport (SYR) to Arturo Merino Benitez Airport (SCL)?
Planning your getaway for October is a great way to save, as it's the cheapest month for flights between SYR and SCL. You'll often find the lowest fares during off-peak months.
What is the cheapest airline that flies from Hancock Intl. Airport (SYR) to Arturo Merino Benitez Airport (SCL)?
To find the cheapest airline flying from SYR to SCL, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and cabin class. You can then sort your results by "Price (lowest to highest)" to see the cheapest flights first.
How many flights per day from Hancock Intl. Airport (SYR) to Arturo Merino Benitez Airport (SCL)?
You'll need to catch a flight with a layover if you're traveling from Hancock Intl. Airport (SYR) to Arturo Merino Benitez Airport (SCL). Direct flights don't operate daily on this route. However, just filter your search to include one or two stops to discover the best option for your trip.
What day of the week has the most flights from SYR to SCL?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Hancock Intl. Airport (SYR) to Arturo Merino Benitez Airport (SCL)?
To arrive at Arturo Merino Benitez Airport (SCL) on time, select a flight that leaves from Hancock Intl. Airport (SYR) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Hancock Intl. Airport (SYR) to Arturo Merino Benitez Airport (SCL) last-minute?
Booking your ticket from SYR to SCL just before your journey is generally more expensive. However, if there's some wiggle room with your schedule, you could score a cheap last-minute fare.
Is it cheaper to book a SYR to SCL flight and hotel package?
Compared with arranging hotels and flights separately, booking a SYR to SCL flight and hotel package with Expedia could result in significant savings. What's more, having it all in one place will take the hassle out of planning your trip. Just pick your flights and choose from our wide range of hotels, then personalize your trip with extras like car rentals and activities.
Can I cancel or change the date of my flight from Hancock Intl. Airport (SYR) to Arturo Merino Benitez Airport (SCL)?
In most cases, you're able to cancel or reschedule your SYR to SCL flight. However, there may be additional charges, especially if you booked over 24 hours ago. Double-check your itinerary for the airline's fees and rules on flight changes, or if you want further details, head to our Customer Service portal.

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*Available to One Key members.