Southern Illinois Luxury Vacations

Book a Luxury Hotel + Flight or Car together to unlock savings

Photo by Southernmost Illinois Tourism Bureau
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Top Luxury vacation packages in Southern Illinois

Price found within the past 48 hours. Click for updated prices.
DoubleTree by Hilton Mt. Vernon
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3 Night Luxury vacations in Southern Illinois

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DoubleTree by Hilton Mt. Vernon
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4 Night Luxury vacations in Southern Illinois

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Days Inn by Wyndham Collinsville/St. Louis
Super 8 by Wyndham Belleville St. Louis Area
Super 8 by Wyndham Troy IL/St. Louis Area
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All you need to know about luxury vacations in Southern Illinois

What can I expect from a luxury Southern Illinois vacation?

Luxury means the very finest of the things you enjoy most. Indulge your every waking moment—and restful night—with a luxury Southern Illinois vacation. Sip handcrafted cocktails by an infinity pool, sink into bliss at a full-service spa with a massage cabana on the beach, and chat, cheers, and laugh through exquisite breakfasts, lunches, and dinners with spectacular views. 

How can I find all-inclusive luxury vacation packages in Southern Illinois?

By refining your filters, the most opulent all-inclusive vacation packages will appear before your eyes. Check the 5* filter to find truly sensational stays. You barely need to lift a finger. 

Can I book a cheap Southern Illinois luxury vacation?

Affordable luxury is only ever a few clicks away. Enter your travel dates and sort the grandiose getaways on offer by price to see the most fiscally friendly retreats first. Filter by budget, too, to find your perfect balance of luxury. Right now, luxury vacations start at $369. Prices and availability are subject to change. Additional terms may apply.

How can I book a luxury family vacation in Southern Illinois?

Tailor your luxury family escape by checking the filters that set the whole family’s hearts a-flutter. Whether that’s wet and wild water parks, heavenly hot tubs, or the kid-quieting magic of free Wi-Fi. 

Can I book a package in Southern Illinois with a luxury vacation home?

A private paradise is true luxury! Filter by property type for houses, villas, and apartments. For an amazingly affordable all-in-one luxury experience, book your accommodation, airfare, and car rental as a package.   

How can I find the best luxury vacation deals in Southern Illinois?

Find absolute delight in the dropdown! Simply sort your tempting search results by deals to find that lean-budget luxury. For a budget conscious stay, consider booking a stay away from big cities or outside the peak months.

Can I book a luxury holiday in Southern Illinois with free cancellation and/or flexible dates?

Freedom and flexibility are the greatest luxuries of all. Get both when you filter by payment option and book a trip with free cancellation or on a buy now, pay later plan. 

Why should I book my luxury trip to Southern Illinois with Expedia?

A luxurious trip follows a stress-free booking experience. Find, build, and book the most glorious of getaways in seconds—with ATOL protection for added peace of mind.

Top Luxury Southern Illinois Hotels

Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area

2 out of 5
910 Edwardsville Rd, Troy, IL
  • 4 hours drive from Shawnee National Forest
Indulge yourself with classy lodging with a stay at Super 8 by Wyndham Troy IL/St. Louis Area, where you'll enjoy amenities like premium channels and more.
7.8/10 Good! (1,003 reviews)
"Good"

Reviewed on Aug 14, 2025

Super 8 by Wyndham Troy IL/St. Louis Area
Rodeway Inn Effingham North

Rodeway Inn Effingham North

2 out of 5
1400 Thelma Keller Ave, Effingham, IL
  • 4 hours drive from Shawnee National Forest
Rodeway Inn Effingham North provides luxe lodging where you'll enjoy premium channels and more.
7.6/10 Good! (1,001 reviews)
"At age 77 & being a Baby Boomer, we like a Human checking us in ' not a Kieosk robot. And..he was a foreigner and it was hard to understand him!!!"

Reviewed on Aug 14, 2025

Rodeway Inn Effingham North
Suite Dreams Hotel

Suite Dreams Hotel

2.5 out of 5
300 Broadway Avenue East, Mattoon, IL
  • 5 hours drive from Shawnee National Forest
Take a lavish vacation in Mattoon. Sought-after amenities at this hotel include 2 bars, a restaurant, and a 24-hour fitness center.
7.2/10 Good! (496 reviews)
"Perfect location to walk to Bagelfest"

Reviewed on Jul 20, 2025

Suite Dreams Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More vacations you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.