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Featured Panama City 4 Star Hotels

See all 166 Properties in Panama City
Hard Rock Hotel Panama Megapolis

Hard Rock Hotel Panama Megapolis

Ave. Balboa al lado de Multicentro, Panama City
  • Free Cancellation
  • Reserve now, pay when you stay
4.5 out of 5.0
 
 
4.3 out of 5 (2,346 reviews)
ExcellentExcellent hotel near a nice mall. Lots of food and shopping options
Jun 19, 2018

Hard Rock Hotel Panama Megapolis$140

Hard Rock Hotel Panama Megapolis$140
Novotel Panama City

Novotel Panama City

Calle Jose I. Fabrega y Thais de Pons, Panama City
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.3 out of 5 (859 reviews)
Nice hotelThe location was fairly good. Several places to eat around. Taxi service a bit higher from those outside the hotel
May 29, 2018

Novotel Panama City$42

Novotel Panama City$42
RIU Plaza Panama

RIU Plaza Panama

Calle 50, Urb. Marbella, Panama City
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.3 out of 5 (1,600 reviews)
Best value in townHad a great experience. This is the best game lace to stay.
Jun 19, 2018

RIU Plaza Panama$86

RIU Plaza Panama$86
Occidental Panamá City by Barceló Hotel Group

Occidental Panamá City by Barceló Hotel Group

Avenida 2da Sur, Obarrio, Bella Vista, Panama City
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.1 out of 5 (805 reviews)
City breakA great location and within walking distance to the metro train station and supermarket. The hotel is very modern and contemporary and the rooms are in good condition. I did not have breakfast or use the hotel's bar or restaurant. However, there were only basic hotel amenities available (no shower ...
Jun 16, 2018
Wyndham Panama Albrook Mall

Wyndham Panama Albrook Mall

Ave. Marginal, Corregimiento de Ancon, Panama City
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.5 out of 5 (825 reviews)
Super hotel The staff was friendly . Breakfast was delicious with a variety of items . Hotel was clean , rooms spacious
Jun 4, 2018

Wyndham Panama Albrook Mall$104

Wyndham Panama Albrook Mall$104
Courtyard Panama at Multiplaza Mall

Courtyard Panama at Multiplaza Mall

Via Israel Multiplaza Pacific Mall, Panama City
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.2 out of 5 (546 reviews)
Convenience alwaysAlways had a lovely stay with them... and always want to stay there. Close to everything we want to go.
May 11, 2018

Courtyard Panama at Multiplaza Mall$64

Courtyard Panama at Multiplaza Mall$64
Hilton Panama

Hilton Panama

Balboa Ave. and Aquilino De La Guardia, Panama City
  • Free Cancellation
  • Reserve now, pay when you stay
4.5 out of 5.0
 
 
4.4 out of 5 (316 reviews)
Great ViewA 4 yr old facility with Great Views, Ocean Front, centrally located
Mar 20, 2018

Hilton Panama$84

Hilton Panama$84
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

Av. Balboa con Calle 53, Panama City
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.3 out of 5 (187 reviews)
I’m a Regular Guest at the Golden TowerI stay here every time I come to Panama City. The staff is friendly and helpful, the beds are lovely and the view is spectacular. Breakfast is exceptional, with a huge selection of breakfast standards and international offerings.
May 20, 2018

Las Americas Golden Tower Panama$132

Las Americas Golden Tower Panama$132
DoubleTree by Hilton Hotel Panama City

DoubleTree by Hilton Hotel Panama City

Via Espana, Federico Boyd & Bella Vista, Panama City
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.1 out of 5 (1,536 reviews)
Great hotel to stay in panama city Great service from the staff, all of them, every day. Call us by our last name and always smiling
May 29, 2018
Eurostars Panama City

Eurostars Panama City

Calle Ricardo Arias, Panama City
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.1 out of 5 (587 reviews)
Good LocationClose to subway, buses, shops and restaurants. Nice hotel but sadly let down by the majority of staff hospitality.
May 27, 2018

Eurostars Panama City$63

Eurostars Panama City$63
Map

The outset of any much-needed trip kicks off with choosing a great destination. Panama City is a popular option with guests because it offers so much. Location is everything, but that applies to more than the area you are flying into. Now that you have a feel for this city, it is time you to get to know your home away from home.

Hotels as Picturesque as Panama City

Panama City saw its fair share of visitors last year. Expedia's comment section contains comments that highlight how astounding these hotels are. The resorts found here aim to make your stay as pleasant as your nights checking out Panama City. These hotels aim to make the grounds and facilities pleasing from the time you step onto the property. You'll never need to search long for an invigorating dip, gourmet lunch, or to keep up with your workout routine during your vacation with all that they offer.

Rooms have been configured to keep you as comfortable as possible, with amenities like in-room tea or coffee, designer bathroom products, and, premium bedding. So, sit back and relax. Moreover, if you find yourself in need of anything else, you can trust the staff will do their best to ensure you continue to be satisfied during your stay. These accommodations are so lovely that you'll regret the day you have to leave.

Book a 4-Star Hotel in Panama City Today!

A getaway to Panama City should be one that you'll recall for years to come, and booking a 4-star hotel will help make those memories nothing but incredible. Review Expedia's wide selection of 4-star hotels in Panama City that will take your trip to greater heights.

Recently booked 4 Star Hotels in Panama City

Hotel Coral Suites
3.5 out of 5.0
Last booking: 9 hours ago
Metro Hotel Panama
3.5 out of 5.0
Last booking: 9 hours ago
Country Inn & Suites by Radisson, Panama Canal, Panama
3.5 out of 5.0
Last booking: 9 hours ago
The Westin Panama
4.0 out of 5.0
Last booking: 9 hours ago
Sortis Hotel, Spa & Casino, Autograph Collection
4.5 out of 5.0
Last booking: 10 hours ago
Hotel Covadonga
2.0 out of 5.0
Last booking: 10 hours ago
Radisson Decapolis Panama City
4.0 out of 5.0
Last booking: 10 hours ago
Plaza Paitilla Inn Hotel
3.5 out of 5.0
Last booking: 11 hours ago
Novotel Panama City
4.0 out of 5.0
Last booking: 11 hours ago