A city skyline with high-rise buildings, a calm waterfront, and a sunset sky.

Find 4 Star Hotels in Panama City from $72

Dates

November 2026

December 2026

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Our total price for your stay includes taxes and fees
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Our top choices for Panama City 4-star hotels

A poolside area with a bar, seating, and a view of the pool.

1. Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Bella Vista

Kayon

$94 nightly

Nov 29 - Nov 30

Total with taxes and fees

A swimming pool with a clear water surface, a poolside area with lounge chairs, and a building with large windows and doors.

2. Crowne Plaza Panama Airport by IHG

Tocumen Airport

Duran

$142 nightly

Nov 19 - Nov 20

Total with taxes and fees

A high-rise building with a modern architectural design, featuring a grid of windows and balconies.

3. Megapolis Hotel Panamá

San Francisco

Amanda

$133 nightly

Nov 9 - Nov 10

Total with taxes and fees

A balcony with wicker chairs and a view of the cityscape.

4. Ramada Plaza by Wyndham Panama Punta Pacifica

San Francisco

Luis

$111 nightly

Nov 9 - Nov 10

Total with taxes and fees

A multi-story building with balconies, arched windows, and decorative railings.

5. Central Hotel Panama Casco Viejo

Casco Viejo

Moejha

$164 nightly

Nov 15 - Nov 16

Total with taxes and fees

A pool area with lounge chairs, umbrellas, and a bridge over the water.

6. Riande Aeropuerto Hotel & Casino

Tocumen Airport

Lidia

$108 nightly

Nov 9 - Nov 10

Total with taxes and fees

A resort with a large swimming pool, thatched-roof structures, and palm trees.

7. Dreams Playa Bonita Panama - All Inclusive

Veracruz

Olga

$263 nightly

Dec 1 - Dec 2

Total with taxes and fees

A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.

8. Courtyard by Marriott Panama Multiplaza Mall

San Francisco

Marine

$131 nightly

Nov 28 - Nov 29

Total with taxes and fees

A modern building with a glass facade, a curved structure, and a flat roof.

9. Decapolis Hotel Panama City

San Francisco

Wladimir

$102 nightly

Nov 9 - Nov 10

Total with taxes and fees

A rooftop pool with lounge chairs and a city skyline view.

10. Hotel Dann Carlton Marinn Place Panama Financial District

Bella Vista

Oscar

$106 nightly

Dec 9 - Dec 10

Total with taxes and fees

An aerial view of a rectangular swimming pool with two lounge chairs and a ladder.

11. Courtyard by Marriott Panama Metromall

San Antonio

Hector

$101 nightly

Nov 27 - Nov 28

Total with taxes and fees

A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.

12. Las Americas Golden Tower Panama

San Francisco

Everlyn

$150 nightly

Nov 22 - Nov 23

Total with taxes and fees

A rooftop pool with sun loungers and a city skyline in the background.

13. Waymore Hotel Spa & Casino

Bella Vista

Bruno

$135 nightly

Nov 10 - Nov 11

Total with taxes and fees

A rooftop swimming pool with lounge chairs and a city skyline in the background.

14. Studio Coliving

Bella Vista

Phillip

A rooftop pool area with lounge chairs and a bar, overlooking a city skyline at sunset.

15. Marriott Panama Hotel

Panama City

Guadalupe

$178 nightly

Dec 4 - Dec 5

Total with taxes and fees

A modern hotel entrance with a prominent 'NOVOTEL' sign, large glass windows, and geometric light patterns on the facade.

16. Novotel Panama City

Bella Vista

CARLOS

$96 nightly

Dec 9 - Dec 10

Total with taxes and fees

A historic building with multiple balconies and a statue of a man on horseback.

17. American Trade Hotel

Casco Viejo

Conrad

$215 nightly

Nov 15 - Nov 16

Total with taxes and fees

A swimming pool with lounge chairs and palm trees, surrounded by modern buildings.

18. Sheraton Grand Panama

San Francisco

Nicole

$183 nightly

Nov 13 - Nov 14

Total with taxes and fees

A poolside area with lounge chairs and umbrellas, overlooking a clear blue sea and a city skyline.

19. Residence Inn by Marriott Panama City

San Francisco

david

$206 nightly

Dec 8 - Dec 9

Total with taxes and fees

A resort with a pool area, lounge chairs, and a view of a bridge at night.

20. Radisson Hotel Panama Canal

Amador

Kevin

$78 nightly

Nov 9 - Nov 10

Total with taxes and fees

Top Panama City Hotel Reviews

A multi-story building with ornate balconies, large windows, and decorative moldings.

Hotel Plaza Herrera

Casco Viejo

10/10 Excellent

Sharon

Ramada Plaza by Wyndham Panama Punta Pacifica

San Francisco

10/10 Excellent

Theon

A multi-story hotel with a classic architectural design, featuring balconies and large windows.

La Concordia Boutique Hotel

Casco Viejo

10/10 Excellent

This hotel was great. Its location is perfect for a loop around the historic area. The staff is friendly, and most are fluent in English. Everything was clean and the room was spacious with a great balcony. They staff the front door 24/7 so no one unwelcome can enter. The rooftop bar and food was great. It isn't open 24/7 but there are plenty of other options for places to eat, and it is open at meal times. Wifi worked well.

Michael

American Trade Hotel

Casco Viejo

10/10 Excellent

We arrived early from the David airport around 10am and we were just going to drop off our bags and they not only held our bags without question but then also took the time to make sure we had our room early if one was available! (Which there was!)-just be aware during their peak season it may not happen we were just lucky in the off season! The staff is SUPER friendly! The door men were super awesome and were always happy to help us! There will be an umbrella for you to get to your car if it’s...

Ashley

A spacious outdoor patio with wicker furniture, potted plants, and umbrellas providing shade.

Hotel San Felipe

Casco Viejo

10/10 Excellent

Carmen

Novotel Panama City

Bella Vista

10/10 Excellent

Blaise

Central Hotel Panama Casco Viejo

Casco Viejo

10/10 Excellent

Lourdes

A rooftop pool with clear blue water, surrounded by palm trees and a city skyline in the background.

Gran Evenia Panama

Bella Vista

10/10 Excellent

Gia

Residence Inn by Marriott Panama City

San Francisco

10/10 Excellent

We read a few pretty bad reviews about this hotel but booked anyway. So now I’m here to report back to my fellow Hotels members. Here’s the deal. The view is amazing. The roof top pool, the gym and the morning and evening views from roof top are SICK!! I’ll upload a pic. 😊 That comment about the mold. Forget about that person. The negative comments about breakfast. Well, yeah they could do better for sure but it’s not a deal maker. If you want a really nice breakfast go to a local...

Chris

A rooftop pool with a city view, lounge chairs, and a clear sky.

Corporate Stays Arcadia | Executive Furnished Apartments

Costa del Este

10/10 Excellent

This place is even more beautiful than the pictures! We stayed in unit 1508 and it felt brand new—super clean, stylish, and in a very safe area. I was nervous about booking last minute, but check-in was smooth. Irving greeted us and made us feel at home. Another huge plus is the location—you’re right across the street from a beautiful, modern mall with tons of great stores, cafes, and restaurants. There’s also a dog park directly across the street, as well as a family-friendly park nearby...

Dinita

Courtyard by Marriott Panama Multiplaza Mall

San Francisco

10/10 Excellent

Sudesh

Hotel Dann Carlton Marinn Place Panama Financial District

Bella Vista

10/10 Excellent

Seongsoo

Waymore Hotel Spa & Casino

Bella Vista

10/10 Excellent

I loved my stay at this hotel. I stayed at this location when it was the Veneto over 12 years ago, & it wasn’t very good for a number of reasons. I am so glad to report that The Waymore is now my favorite hotel in Panama City & I’ve been going to Panama City 1-2xs a year for over 20 years. The location near the metro, good restaurants, markets, Via Argentina (& all it has to offer) are huge advantages. The staff was extremely courteous & spoke English well. The room was spectacular (a junior...

Manuel

A rooftop pool with blue lounge chairs and a city skyline view.

Best Western Plus Panama Zen Hotel

Bella Vista

10/10 Excellent

Maria

A swimming pool with a city skyline in the background.

Modern Design Apartments near Sortis

Bella Vista

10/10 Excellent

Narcisa

Find out more about Panama City

The outset of any much-needed trip kicks off with choosing a great destination. Panama City is a popular option with guests because it offers so much. Location is everything, but that applies to more than the area you are flying into. Now that you have a feel for this city, it is time you to get to know your home away from home.

Hotels as Picturesque as Panama City

Panama City saw its fair share of visitors last year. Expedia's comment section contains comments that highlight how astounding these hotels are. The resorts found here aim to make your stay as pleasant as your nights checking out Panama City. These hotels aim to make the grounds and facilities pleasing from the time you step onto the property. You'll never need to search long for an invigorating dip, gourmet lunch, or to keep up with your workout routine during your vacation with all that they offer.

Rooms have been configured to keep you as comfortable as possible, with amenities like in-room tea or coffee, designer bathroom products, and, premium bedding. So, sit back and relax. Moreover, if you find yourself in need of anything else, you can trust the staff will do their best to ensure you continue to be satisfied during your stay. These accommodations are so lovely that you'll regret the day you have to leave.

Book a 4-Star Hotel in Panama City Today!

A getaway to Panama City should be one that you'll recall for years to come, and booking a 4-star hotel will help make those memories nothing but incredible. Review Expedia's wide selection of 4-star hotels in Panama City that will take your trip to greater heights.

Frequently Asked Questions

What are the best 4-star hotels in Panama City?

Continental Hotel Panamá is a 4-star hotel in Panama City that ranks highly among Expedia travelers. A sauna and dining romance packages are just a couple of its amenities. Travelers also recommend Hotel El Panama by Faranda Grand, a member of Radisson Individuals. From premium bedding to Egyptian-cotton sheets, it offers conveniences that cater to every aspect of your relaxation and enjoyment.

How much does it cost to stay in a 4-star hotel in Panama City?

With Expedia's search and sort filters, scoring an awesome deal on a 4-star hotel in Panama City just got simpler. Start by keying in your chosen travel dates and length of your getaway. Then list the results by price and choose the option that best fits your style and budget.

Search for the lowest price from $72

What's the difference between 5-star and 4-star hotels in Panama City?

Treat yourself to luxury during your Panama City getaway by checking in to a 4-star hotel. As well as featuring upscale accommodations, these properties are usually packed with amenities, including large beds, complimentary bathrobes and more. A 5-star hotel will go above and beyond to make your trip an even more lavish and special one. Concierge assistance, elegant décor and world-class dining are just the start of the superior conveniences and services you'll likely get access to.

Does Panama City have any 4-star all-inclusive resorts?

Search for a 4-star all-inclusive resort in Panama City with our convenient filter tool. If there's nothing available, we do have some alternative options in this destination that make a superb base for your vacation. Hotel El Panama by Faranda Grand, a member of Radisson Individuals and Continental Hotel Panamá are both rated 4 stars and provide an excellent balance between comfort, amenities and value for money.

Are there any 4-star casino hotels in Panama City?

Roll the dice and let the games begin when you book your next casino vacation in Panama City. Hotel El Panama by Faranda Grand, a member of Radisson Individuals and Continental Hotel Panamá are two 4-star options that you can bet on.

What are the top 4-star hotels in downtown Panama City?

Enjoy the sights with ease when you book a stay at Continental Hotel Panamá. Located 0.2 mi north from the heart of downtown Panama City, this 4-star hotel offers the ideal location to get the most out of this vibrant city with the added bonus of an art gallery and a pillowtop mattress.

Are there any 4-star hotels near Marcos A. Gelabert Intl. Airport (PAC)?

Stay at Marriott Panama Hotel if you're jetting into or leaving Panama City via Marcos A. Gelabert Intl. Airport (PAC). This 4-star property is about 0.8 mi away. La Concordia Boutique Hotel is another deluxe choice conveniently situated around 3 mi from the terminal.

Explore a world of travel with Expedia

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Find 4 Star Hotels in Panama City from $72

Upfront pricing

Treat yourself

Be picky

Check prices for these dates

Our top choices for Panama City 4-star hotels

1. Hotel El Panama by Faranda Grand, a member of Radisson Individuals

2. Crowne Plaza Panama Airport by IHG

3. Megapolis Hotel Panamá

4. Ramada Plaza by Wyndham Panama Punta Pacifica

5. Central Hotel Panama Casco Viejo

6. Riande Aeropuerto Hotel & Casino

7. Dreams Playa Bonita Panama - All Inclusive

8. Courtyard by Marriott Panama Multiplaza Mall

9. Decapolis Hotel Panama City

10. Hotel Dann Carlton Marinn Place Panama Financial District

11. Courtyard by Marriott Panama Metromall

12. Las Americas Golden Tower Panama

13. Waymore Hotel Spa & Casino

14. Studio Coliving

15. Marriott Panama Hotel

16. Novotel Panama City

17. American Trade Hotel

18. Sheraton Grand Panama

19. Residence Inn by Marriott Panama City

20. Radisson Hotel Panama Canal

Top Panama City Hotel Reviews

Hotel Plaza Herrera

10/10 Excellent

Find out more about Panama City

Hotels as Picturesque as Panama City

Book a 4-Star Hotel in Panama City Today!

Frequently Asked Questions

What are the best 4-star hotels in Panama City?

How much does it cost to stay in a 4-star hotel in Panama City?

What's the difference between 5-star and 4-star hotels in Panama City?

Does Panama City have any 4-star all-inclusive resorts?

Are there any 4-star casino hotels in Panama City?

What are the top 4-star hotels in downtown Panama City?

Are there any 4-star hotels near Marcos A. Gelabert Intl. Airport (PAC)?

Explore a world of travel with Expedia