Find 5 Star Hotels in Ortygia from $205

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Check availability on Ortygia 5 Star Hotels

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Dec 24 - Dec 25
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Dec 25 - Dec 26
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Dec 26 - Dec 28
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Our top choices for Ortygia 5-star hotels

Exterior
Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
5.0 star property
Ortigia
9.4 out of 10, Exceptional, (252)
"Great location and very friendly staff"
United States
James
$222 nightly
The price is $256
Jan 8 - Jan 9, 2026
Total with taxes and fees
Ortea Palace Hotel, Sicily, Autograph Collection
Aerial view
Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
5.0 star property
Ortigia
9.0 out of 10, Wonderful, (571)
"Great stay!"
United States
Liza
$179 nightly
The price is $209
Jan 15 - Jan 16, 2026
Total with taxes and fees
Grand Hotel Ortigia Siracusa
Building design
Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
5.0 star property
Ortigia
9.6 out of 10, Exceptional, (73)
"Great hotel and saff"
United States
Galina
Grand Hotel Des Ètrangers - The Leading Hotels of the World
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Ortygia.
Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

Via Vittorio Veneto 93 Syracuse SR
$188 nightly
The price is $218 total per night from Dec 25 to Dec 26
$218 total
Dec 25 - Dec 26
Total with taxes and fees
9.4/10 Exceptional! (901 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Ortygia

More than 2,500 years of history are revealed in the form of cathedrals, fountains, and castles on this fascinating island.

See all hotels in Ortygia
Ortygia featuring heritage elements, a coastal town and night scenes

Top Ortygia Hotel Reviews

Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

10/10 Excellent
"breakfast was good"
John 3-night trip
Posted 2 months ago
Grand Hotel Ortigia Siracusa

Find out more about Ortygia

Ortygia Five Star Hotel Information

If you’re searching for the celebrity treatment, the 5 star hotels in Ortygia are your dreams come true. From sprawling resorts to fancy hot spots, theseOrtygia 5 star hotels immerse each traveler in the most elite experience money can buy. Want to unwind with a VIP-worthy spa treatment? These hotels have the leisure you're looking for.

Interested in sampling world-class cuisine? The on-site restaurants at the 5 stars hotels in Ortygia, Sicily, let you do just that. You’ll even be able to book a room (or perhaps a penthouse?) at first-rate hotels near the region’s can’t-miss sights and most bustling shopping centers. Plus, many globe-trotters who visit Ortygia five star hotels find incredible rates and deep discounts thanks to Expedia, so you can score a deal without sacrificing an ounce of quality.

Everything you could possibly want (and a few things you didn’t know you needed): That’s what you’ll receive when you stay at Ortygia 5 star hotels.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Ortygia?
You can find various pricing options for a 5-star hotel in Ortygia on Expedia. How much you'll pay will depend on when you want to travel, length of stay and other factors. Compare available properties for your preferred dates and make use of our pricing and other filters to score the ideal high-end stay.

  • Search for the lowest price per night from $205

What makes a hotel 5 stars in Ortygia?
From high-end restaurants and 24-hour fitness centers to pools and luxury bedding, the 5-star experience in Ortygia is all about comfort and indulgence. But it takes more than just top-notch amenities to receive a 5-star rating. Accommodations must also offer outstanding guest-centric services like in-room beauty treatments, laundry and dry cleaning and concierge services.
Are there any 5-star all-inclusive resorts in Ortygia?
Find an indulgent retreat that includes your room, meals, drinks and entertainment in Ortygia with our filters. Search for properties rated 5 stars and click on the "All inclusive" filter. Double-check what's included in the price. That way, you can take full advantage of the premium perks on offer from the moment you get there.

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