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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Quad Cities and related destinations

Straddling the Mississippi River, this unique cluster of cities offers a blend of Midwestern charm and riverside attractions. Explore the John Deere Pavilion in Moline, then catch a riverboat cruise or enjoy live music at LeClaire Park in Davenport.

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Find out more about Quad Cities

Indulge your every whim on your next sabbatical. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Quad Cities so popular in the last year. There's no reason to delay a getaway to Quad Cities any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Reserve one of our 5-star hotels in Quad Cities and indulge in the finer things in life for a while. You deserve an outstanding getaway.

5-Star Hotels in Quad Cities

You'll have a wonderful time at one of these 5-star hotels. Spa treatments, delicious meals, and one-on-one attention are all at your fingertips. Our numerous hotels in the area will ensure you find the perfect space to kick back after a long day. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What creature comforts do you want in your lodging? A rejuvenating facial treatment to help your cares fall away? A concierge to help you make reservations at that outstanding restaurant? Plush carpeting, piping hot coffees, and even a hot tub in the bathroom...these hotels have it all.

You won't sleep and order room service the entire time, though. Don't worry. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Quad Cities are the perfect place to rest up after a busy day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs.

Make Your Escape

The results are in, and Quad Cities 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. Don't put off your dream vacation any longer. Decide on one of the 5-star hotels in Quad Cities today and soothe yourself in complete comfort tomorrow.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Quad Cities?
The amount you pay for a 5-star hotel in Quad Cities depends on factors like when you want to go and the length of your trip. A top tip for landing the best deal? Use our pricing filters to check out all of the available options for your chosen dates.

  • Search for the lowest price per night from $93

What makes a hotel 5 stars in Quad Cities?
From gourmet restaurants and 24/7 fitness centers to swimming pools and the finest bedding, the 5-star experience in Quad Cities is all about relaxation and luxury. But it takes more than just upscale perks to get a 5-star rating. Stays must also deliver extraordinary services like in-room beauty treatments, on-site dry cleaning and laundry and 24/7 room service.
Are there any 5-star all-inclusive resorts in Quad Cities?
Use Expedia's filters to find an upmarket escape in Quad Cities where everything you need is included in the price. From there, narrow your results for accommodations that have a rating of 5 stars and are listed as "All inclusive." The most important thing on the schedule at these stays? Pure enjoyment and indulgence.