Title: The Best 5 Star Hotels in Santa Clara from $80 | Expedia.com [Santa Clara Travel Guide](https://expedia.com/Santa-Clara.dx6058653)[Hotels in Santa Clara](https://expedia.com/Santa-Clara-Hotels.d6058653.Travel-Guide-Hotels)[Vacation Rentals in Santa Clara](https://expedia.com/Santa-Clara-Vacation-Rentals.d6058653.Travel-Guide-VacationRentals)[Flights to Santa Clara](https://expedia.com/Cheap-Flights-To-Santa-Clara.d6058653.Travel-Guide-Flights)[Things to do in Santa Clara](https://expedia.com/Things-To-Do-In-Santa-Clara.d6058653.Travel-Guide-Activities)[Car Rentals in Santa Clara](https://expedia.com/Car-Rentals-In-Santa-Clara.d6058653.Car-Rental-Guide)[Santa Clara Vacation Packages](https://expedia.com/Santa-Clara.d6058653.Destination-Travel-Guides) ![Santa Clara, Panama](https://images.trvl-media.com/place/761868027631120384/c9109d40-0482-4f87-bd9c-c8a1df8e2b0c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/761868027631120384/c9109d40-0482-4f87-bd9c-c8a1df8e2b0c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Clara 5 Star Hotels Tonight [Mar 31 - Apr 1](https://www.expedia.com/Hotel-Search?regionId=6058653&startDate=2026-03-31&endDate=2026-04-01&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 1 - Apr 2](https://www.expedia.com/Hotel-Search?regionId=6058653&startDate=2026-04-01&endDate=2026-04-02&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=6058653&startDate=2026-04-03&endDate=2026-04-05&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=6058653&startDate=2026-04-10&endDate=2026-04-12&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Clara 5-star hotels ![12 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/9da9e571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/9ca640da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Villa, 4 Bedrooms, Resort View | Frette Italian sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/232137bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/60de636a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Buenaventura Golf & Beach Resort Panama, Autograph Collection [](https://www.expedia.com/El-Chiru-Hotels-The-Buenaventura-Golf-Beach-Resort-Panama.h2499390.Hotel-Information) El Chiru 9.2/10 Wonderful (733 reviews) "Excellent, robust property with all the activities and amenities you could want for a beach and golf resort. Top notch-best in Panama!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James $220 nightly $242 total Apr 9 - Apr 10 Total with taxes and fees [](https://www.expedia.com/El-Chiru-Hotels-The-Buenaventura-Golf-Beach-Resort-Panama.h2499390.Hotel-Information) ![Couples treatment rooms, sauna, steam room, Turkish bath](https://images.trvl-media.com/lodging/112000000/111210000/111207500/111207482/0362f822.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111210000/111207500/111207482/w5989h3988x0y0-bc4b4741.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111210000/111207500/111207482/e700615b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, sauna, steam room, Turkish bath](https://images.trvl-media.com/lodging/112000000/111210000/111207500/111207482/c72e250d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel La Compania Del Valle [](https://www.expedia.com/El-Valle-De-Anton-Hotels-Hotel-La-Compania-Del-Valle.h111207482.Hotel-Information) El Valle de Anton 9.8/10 Exceptional (100 reviews) "Wow the artwork was amazing. Loved the happy hour. Lovely hotel" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Jane $259 nightly $285 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/El-Valle-De-Anton-Hotels-Hotel-La-Compania-Del-Valle.h111207482.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Santa-Clara-Hotels.s50-0-d6058653.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Santa-Clara-Hotels.s50-0-d6058653.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Clara. ![Playa Blanca Beach Resort - All Inclusive](https://images.trvl-media.com/lodging/1000000/970000/967200/967117/09199a01_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Playa Blanca Beach Resort - All Inclusive 115 Km Via Interamericana Rio Hato Cocle $163 nightly $180 total Apr 29 - Apr 30 Total with taxes and fees 6.6/10 (1,000 reviews) [](https://expedia.com/Rio-Hato-Hotels-Playa-Blanca-Beach-Resort-All-Inclusive.h967117.Hotel-Information) ![Casa Blanca](https://images.trvl-media.com/lodging/106000000/105820000/105811400/105811314/762c9153_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Casa Blanca 5 95-5 San Carlos District San Carlos $73 nightly $80 total Apr 1 - Apr 2 Total with taxes and fees 4/10 (1 review) [](https://expedia.com/San-Carlos-Hotels-Casa-Blanca.h105811314.Hotel-Information) ![Gran Evenia Bijao - All Inclusive](https://images.trvl-media.com/lodging/5000000/4640000/4632200/4632198/e87379ef_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Gran Evenia Bijao - All Inclusive Carretera Interamericana km 108, guias de Anton Rio Hato Coclé [Get rates](https://expedia.com/Hotel-Search?startDate=4%2F14%2F2026&endDate=4%2F15%2F2026&selected=4632198&PinnedHotelID=4632198&HadPinnedHotel=true®ionId=6058653) 7.4/10 Good! (1,000 reviews) [](https://expedia.com/Rio-Hato-Hotels-Gran-Evenia-Bijao-All-Inclusive.h4632198.Hotel-Information) Still don't see what you're looking for? [See all properties in Santa Clara.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F1%2F2026&endDate=4%2F2%2F2026®ionId=6058653&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F1%2F2026&endDate=4%2F2%2F2026®ionId=6058653&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F1%2F2026&endDate=4%2F2%2F2026®ionId=6058653&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F1%2F2026&endDate=4%2F2%2F2026®ionId=6058653&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F1%2F2026&endDate=4%2F2%2F2026®ionId=6058653&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F1%2F2026&endDate=4%2F2%2F2026®ionId=6058653&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Santa Clara Pristine white sands stretch along Santa Clara Beach where families gather for weekend picnics and sunset swims. Nearby Farallon Island offers excellent snorkeling opportunities, while La Casa de Lourdes Outdoor Spa provides a tranquil retreat after days spent under the tropical sun. [See all hotels in Santa Clara](https://www.expedia.com/Hotel-Search?startDate=2026-04-14&endDate=2026-04-15&adults=2®ionId=6058653) ![Santa Clara, Panama](https://images.trvl-media.com/place/761868027631120384/c9109d40-0482-4f87-bd9c-c8a1df8e2b0c.jpg?impolicy=fcrop&w=900&h=450&p=1&q=high) ## Top Santa Clara Hotel Reviews ![The Buenaventura Golf & Beach Resort Panama, Autograph Collection](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/9da9e571_y.jpg) ### The Buenaventura Golf & Beach Resort Panama, Autograph Collection 10/10 Excellent "Clean rooms, amazing staff and food" [](https://expedia.com/El-Chiru-Hotels-The-Buenaventura-Golf-Beach-Resort-Panama.h2499390.Hotel-Information) ![Hotel La Compania Del Valle](https://images.trvl-media.com/lodging/112000000/111210000/111207500/111207482/0362f822_y.jpg) ### Hotel La Compania Del Valle 10/10 Excellent "Brand new property with clean spacious rooms. Ample storage in the room and large bathroom with walk in shower and Molton brown toiletries. There was complimentary bottled water although the tap water is safe to drink, and 6 complimentary coffee pods a day. The yoga instructor was excellent and the yoga was complimentary 9am Thursday to Monday on a roof terrace on the spa. There is a roof terrace bar with amazing views of the surrounding mountains with complimentary drinks for guests each evening 5pm to 7pm which was a really nice touch. All the staff are professional and friendly. The breakfasts are excellent quality and lots of variety. The dinners in the terra vegetarian restaurant and tempo restaurants were excellent quality. We didn’t eat in fuego so can’t comment on that. The food prices are at the higher end but all great quality. We paid around $70-80 for 2 people for 2 courses each and 1 drink each. Our only criticism was the room rate included breakfast however we were charged extra ($30 for 2) for a takeout breakfast on the day we had an early pick up for a trip out with a guide which was a bit steep given the room rate. There were lots of birds in the area and the hotel could attract many to the gardens/grounds if the hummingbird feeders were regularly replenished (they were practically empty our full 5 day stay). A suggestion would be to use up any left over fruit such as papaya or banana to set up a feeding station for wild birds in the hotel gardens " [](https://expedia.com/El-Valle-De-Anton-Hotels-Hotel-La-Compania-Del-Valle.h111207482.Hotel-Information) ## Find out more about Santa Clara Ready for an incredible adventure? Add even more luxury on your next trip to Santa Clara by treating yourself to the best of the best when it comes to lodging. It's an ideal combination. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Santa Clara so popular in the last year. There's no reason to delay a getaway to Santa Clara any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Reserve one of our 5-star hotels in Santa Clara and indulge in the finer things in life for a while. What are you waiting for? ### Book the Best Santa Clara 5-Star Hotels You'll have a wonderful time at one of these 5-star hotels. Highly-rated eateries, top-notch customer care, and rejuvenating spa offerings are all on offer. You're sure to find exactly the accommodation you need. You'll also enjoy a high standard of care and meticulous guest relations, so get ready for a wonderful adventure. How do you want to relax? A mud wrap treatment that will leave you feeling like a million bucks? 24-hour room service, so you can order that filet mignon in the wee hours of the morning? A full-body massage to help your cares fall away? Ready for experiences outside your hotel room? You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Santa Clara are waiting for you to rest up after a busy day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs. ### Your Getaway Starts Today The results are in, and Santa Clara 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. Don't put off your dream vacation any longer. Select one of our Santa Clara 5-star hotels today and soothe yourself in luxe surroundings tomorrow. ## Frequently asked questions ### What are the best 5-star hotels in Santa Clara? ### How much does it cost to stay in a 5-star hotel in Santa Clara? > - Search for the lowest price per night from $80 ### What makes a hotel 5 stars in Santa Clara? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near Santa Clara Beach ](https://www.expedia.com/Santa-Clara-Beach-Hotels.0-l6252721-0.Travel-Guide-Filter-Hotels) - [Hotels near Scarlett Martinez Intl. ](https://www.expedia.com/Scarlett-Martinez-Intl-Airport-Hotels.0-aRIH-0.Travel-Guide-Filter-Hotels) - [Hotels near Farallón Beach ](https://www.expedia.com/Farallon-Beach-Hotels.0-l6034036-0.Travel-Guide-Filter-Hotels) - [Hotels near Costa Blanca ](https://www.expedia.com/Costa-Blanca-Rio-Hato-Hotels.0-n553248635976398650-0.Travel-Guide-Filter-Hotels) - [All-Inclusive Resorts in El Farallón del Chirú ](https://www.expedia.com/El-Farallon-Del-Chiru-Hotels-All-Inclusive-Hotel.0-0-d553248629421993728-tAllinclusiveHotel.Travel-Guide-Filter-Hotels) - 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[Flights from Denver (DEN) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/den/rih/denver-to-rio-hato) - [Flights from Seattle (SEA) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/sea/rih/seattle-to-rio-hato) - [Flights from Bogotá (BOG) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/bog/rih/bogota-to-rio-hato) - [Flights from Panama City (PAC) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/pac/rih/panama-city-to-rio-hato) - [Flights from San José (SJO) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/sjo/rih/san-jose-to-rio-hato) - [Flights from Calgary (YYC) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/yyc/rih/calgary-to-rio-hato) - [Flights from Cincinnati (CVG) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/cvg/rih/cincinnati-to-rio-hato) - [Flights from Vancouver (YVR) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/yvr/rih/vancouver-to-rio-hato) - [Flights from Detroit (DTW) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/dtw/rih/detroit-to-rio-hato) - [Flights from Liberia (LIR) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/lir/rih/liberia-to-rio-hato) - [Flights from Pittsburgh (PIT) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/pit/rih/pittsburgh-to-rio-hato) - [Flights from Buffalo (BUF) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/buf/rih/buffalo-to-rio-hato) - [Flights from Kansas City (MCI) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/mci/rih/kansas-city-to-rio-hato) - [Flights from Indianapolis (IND) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/ind/rih/indianapolis-to-rio-hato) - [Flights from Las Vegas (LAS) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/las/rih/las-vegas-to-rio-hato) - [Flights from Memphis (MEM) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/mem/rih/memphis-to-rio-hato) - [Flights from Portland (PDX) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/pdx/rih/portland-to-rio-hato) - [Flights from Bocas del Toro (BOC) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/boc/rih/bocas-del-toro-to-rio-hato) - [Flights from Lima (LIM) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/lim/rih/lima-to-rio-hato) - [Flights from Hamilton (YHM) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/yhm/rih/hamilton-to-rio-hato) - [Flights from Medellín (MDE) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/mde/rih/medellin-to-rio-hato) - [Flights from Panama City (ECP) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/ecp/rih/panama-city-to-rio-hato) - [Flights from St. John's (YYT) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/yyt/rih/st-johns-to-rio-hato) - [Flights from San Antonio (SAT) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/sat/rih/san-antonio-to-rio-hato) - [Flights from Mexico City (MEX) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/mex/rih/mexico-city-to-rio-hato) - [Flights from Milwaukee (MKE) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/mke/rih/milwaukee-to-rio-hato) - [Flights from Managua (MGA) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/mga/rih/managua-to-rio-hato) - [Flights from Edmonton (YEG) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/yeg/rih/edmonton-to-rio-hato) - [Flights from Cleveland (CLE) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/cle/rih/cleveland-to-rio-hato) - [Flights from New Orleans (MSY) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/msy/rih/new-orleans-to-rio-hato) - [Flights from Contadora Island (OTD) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/otd/rih/contadora-island-to-rio-hato) - [Flights from Guatemala City (GUA) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/gua/rih/guatemala-city-to-rio-hato) - [Flights from Oklahoma City (OKC) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/okc/rih/oklahoma-city-to-rio-hato) - [Flights from Vienna (VIE) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/vie/rih/vienna-to-rio-hato) - [Flights from Frankfurt (FRA) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/fra/rih/frankfurt-to-rio-hato) - [Flights from Quito (UIO) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/uio/rih/quito-to-rio-hato) - [Flights from Montreal (YMQ) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/ymq/rih/montreal-to-rio-hato) - [Flights from Winnipeg (YWG) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/ywg/rih/winnipeg-to-rio-hato) - [Flights from San Salvador (SAL) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/sal/rih/san-salvador-to-rio-hato) - [Santa Clara Beach ](https://www.expedia.com/Santa-Clara-Beach-Rio-Hato.d6252721.Vacation-Attraction) - [Farallón Beach ](https://www.expedia.com/Farallon-Beach-Rio-Hato.d6034036.Vacation-Attraction) - [Visit El Farallón del Chirú ](https://www.expedia.com/El-Farallon-Del-Chiru.dx553248629421993728) - [El Farallón del Chirú Vacations ](https://www.expedia.com/El-Farallon-Del-Chiru.d553248629421993728.Destination-Travel-Guides) - [Farallon Island ](https://www.expedia.com/Farallon-Island-Rio-Hato.d553248621558115504.Vacation-Attraction) - [Visit Las Guias Occidente ](https://www.expedia.com/Las-Guias-Occidente.dx553248623142929245) - [La Casa de Lourdes Outdoor Spa ](https://www.expedia.com/La-Casa-De-Lourdes-Outdoor-Spa-Rio-Hato.d553248621532611584.Vacation-Attraction) - [Playa Blanca ](https://www.expedia.com/Playa-Blanca-Rio-Hato.d6125220.Vacation-Attraction) - [Car rentals near Santa Clara Beach ](https://www.expedia.com/Car-Rentals-In-Santa-Clara-Beach.d6252721.Car-Rental-Guide) - [Car rental Rio Hato Airport (RIH) ](https://www.expedia.com/Car-Rentals-In-Scarlett-Martinez-Intl.d6338030.Car-Rental-Guide) - [Car rentals near Farallón Beach ](https://www.expedia.com/Car-Rentals-In-Farallon-Beach.d6034036.Car-Rental-Guide) - [Car rentals near El Farallón del Chirú ](https://www.expedia.com/Car-Rentals-In-El-Farallon-Del-Chiru.d553248629421993728.Car-Rental-Guide) - [Suv Car Rentals in El Farallón del Chirú ](https://www.expedia.com/SUV-Car-Rentals-In-El-Farallon-Del-Chiru.d553248629421993728-tSUV.Car-Rental-Guide-Class) - [El Farallón del Chirú Vacation Rentals ](https://www.expedia.com/El-Farallon-Del-Chiru-Vacation-Rentals.d553248629421993728.Travel-Guide-VacationRentals) - [Things to do in El Farallón del Chirú ](https://www.expedia.com/Things-To-Do-In-El-Farallon-Del-Chiru.d553248629421993728.Travel-Guide-Activities)