Title: The Best 5 Star Hotels in Santa Clara from $80 | Expedia.com [Santa Clara Travel Guide](https://expedia.com/Santa-Clara.dx6058653)[Hotels in Santa Clara](https://expedia.com/Santa-Clara-Hotels.d6058653.Travel-Guide-Hotels)[Vacation Rentals in Santa Clara](https://expedia.com/Santa-Clara-Vacation-Rentals.d6058653.Travel-Guide-VacationRentals)[Flights to Santa Clara](https://expedia.com/Cheap-Flights-To-Santa-Clara.d6058653.Travel-Guide-Flights)[Things to do in Santa Clara](https://expedia.com/Things-To-Do-In-Santa-Clara.d6058653.Travel-Guide-Activities)[Car Rentals in Santa Clara](https://expedia.com/Car-Rentals-In-Santa-Clara.d6058653.Car-Rental-Guide)[Santa Clara Vacation Packages](https://expedia.com/Santa-Clara.d6058653.Destination-Travel-Guides) ![Santa Clara, Panama](https://images.trvl-media.com/place/761868027631120384/c9109d40-0482-4f87-bd9c-c8a1df8e2b0c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/761868027631120384/c9109d40-0482-4f87-bd9c-c8a1df8e2b0c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Clara 5 Star Hotels Tonight [Mar 18 - Mar 19](https://www.expedia.com/Hotel-Search?regionId=6058653&startDate=2026-03-18&endDate=2026-03-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 19 - Mar 20](https://www.expedia.com/Hotel-Search?regionId=6058653&startDate=2026-03-19&endDate=2026-03-20&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=6058653&startDate=2026-03-20&endDate=2026-03-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=6058653&startDate=2026-03-27&endDate=2026-03-29&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Clara 5-star hotels ![12 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/9da9e571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![7 restaurants, breakfast, lunch, dinner served; international cuisine](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/23a76ff8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/9ca640da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Villa, 4 Bedrooms, Resort View | Frette Italian sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/232137bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Buenaventura Golf & Beach Resort Panama, Autograph Collection [](https://www.expedia.com/El-Chiru-Hotels-The-Buenaventura-Golf-Beach-Resort-Panama.h2499390.Hotel-Information) El Chiru 9.2/10 Wonderful (723 reviews) "The property is beautiful and our kids loved their time in the many pools - as well as in the ocean! My one minor complaint is that the shower leaked out the bottom of the door - otherwise, everything was great!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Amy $220 nightly $242 total Apr 9 - Apr 10 Total with taxes and fees [](https://www.expedia.com/El-Chiru-Hotels-The-Buenaventura-Golf-Beach-Resort-Panama.h2499390.Hotel-Information) ![Couples treatment rooms, sauna, steam room, Turkish bath](https://images.trvl-media.com/lodging/112000000/111210000/111207500/111207482/0362f822.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111210000/111207500/111207482/e700615b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, sauna, steam room, Turkish bath](https://images.trvl-media.com/lodging/112000000/111210000/111207500/111207482/5b4cfa5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111210000/111207500/111207482/w5989h3988x0y0-bc4b4741.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel La Compania Del Valle [](https://www.expedia.com/El-Valle-De-Anton-Hotels-Hotel-La-Compania-Del-Valle.h111207482.Hotel-Information) El Valle de Anton 9.8/10 Exceptional (97 reviews) "Wow the artwork was amazing. Loved the happy hour. Lovely hotel" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Jane $259 nightly $285 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/El-Valle-De-Anton-Hotels-Hotel-La-Compania-Del-Valle.h111207482.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Santa-Clara-Hotels.s50-0-d6058653.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Santa-Clara-Hotels.s50-0-d6058653.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Clara. ![Playa Blanca Beach Resort - All Inclusive](https://images.trvl-media.com/lodging/1000000/970000/967200/967117/09199a01_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Playa Blanca Beach Resort - All Inclusive 115 Km Via Interamericana Rio Hato Cocle $170 nightly $187 total Mar 25 - Mar 26 Total with taxes and fees [](https://expedia.com/Rio-Hato-Hotels-Playa-Blanca-Beach-Resort-All-Inclusive.h967117.Hotel-Information) ![Casa Blanca](https://images.trvl-media.com/lodging/106000000/105820000/105811400/105811314/762c9153_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Casa Blanca 5 95-5 San Carlos District San Carlos $73 nightly $80 total Mar 19 - Mar 20 Total with taxes and fees 4/10 (1 review) [](https://expedia.com/San-Carlos-Hotels-Casa-Blanca.h105811314.Hotel-Information) ![Gran Evenia Bijao - All Inclusive](https://images.trvl-media.com/lodging/5000000/4640000/4632200/4632198/e87379ef_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Gran Evenia Bijao - All Inclusive Carretera Interamericana km 108, guias de Anton Rio Hato Coclé [Get rates](https://expedia.com/Hotel-Search?startDate=4%2F1%2F2026&endDate=4%2F2%2F2026&selected=4632198&PinnedHotelID=4632198&HadPinnedHotel=true®ionId=6058653) 7.4/10 Good! (1,001 reviews) [](https://expedia.com/Rio-Hato-Hotels-Gran-Evenia-Bijao-All-Inclusive.h4632198.Hotel-Information) Still don't see what you're looking for? [See all properties in Santa Clara.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F19%2F2026&endDate=3%2F20%2F2026®ionId=6058653&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F19%2F2026&endDate=3%2F20%2F2026®ionId=6058653&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F19%2F2026&endDate=3%2F20%2F2026®ionId=6058653&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F19%2F2026&endDate=3%2F20%2F2026®ionId=6058653&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F19%2F2026&endDate=3%2F20%2F2026®ionId=6058653&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F19%2F2026&endDate=3%2F20%2F2026®ionId=6058653&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Santa Clara Pristine white sands stretch along Santa Clara Beach where families gather for weekend picnics and sunset swims. Nearby Farallon Island offers excellent snorkeling opportunities, while La Casa de Lourdes Outdoor Spa provides a tranquil retreat after days spent under the tropical sun. [See all hotels in Santa Clara](https://www.expedia.com/Hotel-Search?startDate=2026-04-01&endDate=2026-04-02&adults=2®ionId=6058653) ![Santa Clara, Panama](https://images.trvl-media.com/place/761868027631120384/c9109d40-0482-4f87-bd9c-c8a1df8e2b0c.jpg?impolicy=fcrop&w=900&h=450&p=1&q=high) ## Top Santa Clara Hotel Reviews ![The Buenaventura Golf & Beach Resort Panama, Autograph Collection](https://images.trvl-media.com/lodging/3000000/2500000/2499400/2499390/9da9e571_y.jpg) ### The Buenaventura Golf & Beach Resort Panama, Autograph Collection 10/10 Excellent "Absolutely stunning property with great staff and service. Exceptionally clean, great rooms, heavenly beds, great food/restaurants, beautiful beach and pool area. The shuttle service is very helpful for the massive property. Didn't get to golf this trip but the course is in great condition as well. The place is dead after 9pm, which wasn't an issue for us but could be to some people who are looking for some sort of nightlife/bars. If possible fly into the new airport to avoid the 2 hour drive from Tocumen (new airport is 15 mins away) but not a big issue either way. Will absolutely be visiting again! " [](https://expedia.com/El-Chiru-Hotels-The-Buenaventura-Golf-Beach-Resort-Panama.h2499390.Hotel-Information) ![Hotel La Compania Del Valle](https://images.trvl-media.com/lodging/112000000/111210000/111207500/111207482/0362f822_y.jpg) ### Hotel La Compania Del Valle 10/10 Excellent "We wish we could have had time to use the spa, but not on this trip. The property was stunning, the pools were perfect, the complimentary happy hour was a very pleasant surprise, the food at Fuego was amazing, the complimentary breakfasts were the best among the 4 hotels we stayed at on our trip. Everything was super clean and well maintained and we loved checking out the art everywhere we walked!" [](https://expedia.com/El-Valle-De-Anton-Hotels-Hotel-La-Compania-Del-Valle.h111207482.Hotel-Information) ## Find out more about Santa Clara Ready for an incredible adventure? Add even more luxury on your next trip to Santa Clara by treating yourself to the best of the best when it comes to lodging. It's an ideal combination. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Santa Clara so popular in the last year. There's no reason to delay a getaway to Santa Clara any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Reserve one of our 5-star hotels in Santa Clara and indulge in the finer things in life for a while. What are you waiting for? ### Book the Best Santa Clara 5-Star Hotels You'll have a wonderful time at one of these 5-star hotels. Highly-rated eateries, top-notch customer care, and rejuvenating spa offerings are all on offer. You're sure to find exactly the accommodation you need. You'll also enjoy a high standard of care and meticulous guest relations, so get ready for a wonderful adventure. How do you want to relax? A mud wrap treatment that will leave you feeling like a million bucks? 24-hour room service, so you can order that filet mignon in the wee hours of the morning? A full-body massage to help your cares fall away? Ready for experiences outside your hotel room? You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Santa Clara are waiting for you to rest up after a busy day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs. ### Your Getaway Starts Today The results are in, and Santa Clara 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. Don't put off your dream vacation any longer. Select one of our Santa Clara 5-star hotels today and soothe yourself in luxe surroundings tomorrow. ## Frequently asked questions ### What are the best 5-star hotels in Santa Clara? ### How much does it cost to stay in a 5-star hotel in Santa Clara? > - Search for the lowest price per night from $80 ### What makes a hotel 5 stars in Santa Clara? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near Santa Clara Beach ](https://www.expedia.com/Santa-Clara-Beach-Hotels.0-l6252721-0.Travel-Guide-Filter-Hotels) - [Hotels near Scarlett Martinez Intl. ](https://www.expedia.com/Scarlett-Martinez-Intl-Airport-Hotels.0-aRIH-0.Travel-Guide-Filter-Hotels) - [Hotels near Farallón Beach ](https://www.expedia.com/Farallon-Beach-Hotels.0-l6034036-0.Travel-Guide-Filter-Hotels) - [Hotels near Costa Blanca ](https://www.expedia.com/Costa-Blanca-Rio-Hato-Hotels.0-n553248635976398650-0.Travel-Guide-Filter-Hotels) - [All-Inclusive Resorts in El Farallón del Chirú ](https://www.expedia.com/El-Farallon-Del-Chiru-Hotels-All-Inclusive-Hotel.0-0-d553248629421993728-tAllinclusiveHotel.Travel-Guide-Filter-Hotels) - 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[Flights from Denver (DEN) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/den/rih/denver-to-rio-hato) - [Flights from Seattle (SEA) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/sea/rih/seattle-to-rio-hato) - [Flights from Bogotá (BOG) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/bog/rih/bogota-to-rio-hato) - [Flights from Panama City (PAC) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/pac/rih/panama-city-to-rio-hato) - [Flights from San José (SJO) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/sjo/rih/san-jose-to-rio-hato) - [Flights from Calgary (YYC) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/yyc/rih/calgary-to-rio-hato) - [Flights from Cincinnati (CVG) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/cvg/rih/cincinnati-to-rio-hato) - [Flights from Vancouver (YVR) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/yvr/rih/vancouver-to-rio-hato) - [Flights from Detroit (DTW) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/dtw/rih/detroit-to-rio-hato) - [Flights from Liberia (LIR) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/lir/rih/liberia-to-rio-hato) - [Flights from Pittsburgh (PIT) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/pit/rih/pittsburgh-to-rio-hato) - [Flights from Buffalo (BUF) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/buf/rih/buffalo-to-rio-hato) - [Flights from Kansas City (MCI) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/mci/rih/kansas-city-to-rio-hato) - [Flights from Indianapolis (IND) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/ind/rih/indianapolis-to-rio-hato) - [Flights from Las Vegas (LAS) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/las/rih/las-vegas-to-rio-hato) - [Flights from Memphis (MEM) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/mem/rih/memphis-to-rio-hato) - [Flights from Portland (PDX) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/pdx/rih/portland-to-rio-hato) - [Flights from Bocas del Toro (BOC) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/boc/rih/bocas-del-toro-to-rio-hato) - [Flights from Lima (LIM) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/lim/rih/lima-to-rio-hato) - [Flights from Hamilton (YHM) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/yhm/rih/hamilton-to-rio-hato) - [Flights from Medellín (MDE) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/mde/rih/medellin-to-rio-hato) - [Flights from Panama City (ECP) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/ecp/rih/panama-city-to-rio-hato) - [Flights from St. John's (YYT) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/yyt/rih/st-johns-to-rio-hato) - [Flights from San Antonio (SAT) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/sat/rih/san-antonio-to-rio-hato) - [Flights from Mexico City (MEX) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/mex/rih/mexico-city-to-rio-hato) - [Flights from Milwaukee (MKE) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/mke/rih/milwaukee-to-rio-hato) - [Flights from Managua (MGA) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/mga/rih/managua-to-rio-hato) - [Flights from Edmonton (YEG) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/yeg/rih/edmonton-to-rio-hato) - [Flights from Cleveland (CLE) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/cle/rih/cleveland-to-rio-hato) - [Flights from New Orleans (MSY) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/msy/rih/new-orleans-to-rio-hato) - [Flights from Contadora Island (OTD) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/otd/rih/contadora-island-to-rio-hato) - [Flights from Guatemala City (GUA) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/gua/rih/guatemala-city-to-rio-hato) - [Flights from Oklahoma City (OKC) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/okc/rih/oklahoma-city-to-rio-hato) - [Flights from Vienna (VIE) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/vie/rih/vienna-to-rio-hato) - [Flights from Frankfurt (FRA) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/fra/rih/frankfurt-to-rio-hato) - [Flights from Quito (UIO) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/uio/rih/quito-to-rio-hato) - [Flights from Montreal (YMQ) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/ymq/rih/montreal-to-rio-hato) - [Flights from Winnipeg (YWG) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/ywg/rih/winnipeg-to-rio-hato) - [Flights from San Salvador (SAL) to Rio Hato (RIH) ](https://www.expedia.com/lp/flights/sal/rih/san-salvador-to-rio-hato) - [Santa Clara Beach ](https://www.expedia.com/Santa-Clara-Beach-Rio-Hato.d6252721.Vacation-Attraction) - [Farallón Beach ](https://www.expedia.com/Farallon-Beach-Rio-Hato.d6034036.Vacation-Attraction) - [Visit El Farallón del Chirú ](https://www.expedia.com/El-Farallon-Del-Chiru.dx553248629421993728) - [El Farallón del Chirú Vacations ](https://www.expedia.com/El-Farallon-Del-Chiru.d553248629421993728.Destination-Travel-Guides) - [Farallon Island ](https://www.expedia.com/Farallon-Island-Rio-Hato.d553248621558115504.Vacation-Attraction) - [Visit Las Guias Occidente ](https://www.expedia.com/Las-Guias-Occidente.dx553248623142929245) - [La Casa de Lourdes Outdoor Spa ](https://www.expedia.com/La-Casa-De-Lourdes-Outdoor-Spa-Rio-Hato.d553248621532611584.Vacation-Attraction) - [Playa Blanca ](https://www.expedia.com/Playa-Blanca-Rio-Hato.d6125220.Vacation-Attraction) - [Car rentals near Santa Clara Beach ](https://www.expedia.com/Car-Rentals-In-Santa-Clara-Beach.d6252721.Car-Rental-Guide) - [Car rental Rio Hato Airport (RIH) ](https://www.expedia.com/Car-Rentals-In-Scarlett-Martinez-Intl.d6338030.Car-Rental-Guide) - [Car rentals near Farallón Beach ](https://www.expedia.com/Car-Rentals-In-Farallon-Beach.d6034036.Car-Rental-Guide) - [Car rentals near El Farallón del Chirú ](https://www.expedia.com/Car-Rentals-In-El-Farallon-Del-Chiru.d553248629421993728.Car-Rental-Guide) - [Suv Car Rentals in El Farallón del Chirú ](https://www.expedia.com/SUV-Car-Rentals-In-El-Farallon-Del-Chiru.d553248629421993728-tSUV.Car-Rental-Guide-Class) - [El Farallón del Chirú Vacation Rentals ](https://www.expedia.com/El-Farallon-Del-Chiru-Vacation-Rentals.d553248629421993728.Travel-Guide-VacationRentals) - [Things to do in El Farallón del Chirú ](https://www.expedia.com/Things-To-Do-In-El-Farallon-Del-Chiru.d553248629421993728.Travel-Guide-Activities)