Santa Clara Vacations from $983

Book a Hotel + Flight or Car together to unlock savings

Your Santa Clara Vacation

Enjoy amazing adventures when you lock in a vacation package to Santa Clara. Whether you're a history buff, art enthusiast or just a traveler who loves discovering new places, there's something for everyone in this lively city. Every trip to Santa Clara needs a well-planned itinerary. Fill yours with big-name attractions like Farallon Island, La Casa de Lourdes Outdoor Spa and Parroquia Santiago Apóstol de Río Hato. Stop dreaming and start traveling. Explore the many options on Expedia today and put your Santa Clara vacation plans in motion!

The Latest Santa Clara vacation packages

Price found within the past 48 hours. Click for updated prices.
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Save 100% on your flight
Price was $1,819, price is now $983 per person
$983
per person
Dec 24 - Dec 27
found 2 days ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
8.6/10 Excellent! (1,803 reviews)
Very clean rooms and we'll maintained property

Reviewed on Oct 28, 2026

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $2,308, price is now $1,250 per person
$1,250
per person
Dec 24 - Dec 27
found 2 days ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9.2/10 Wonderful! (1,015 reviews)

Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House

3 out of 5
Casco Viejo
Save 100% on your flight
Price was $1,895, price is now $1,329 per person
$1,329
per person
Dec 23 - Dec 27
found 23 hours ago
Roundtrip flight included
Georgetown (GEO) to Panama City (PTY)
9.6/10 Exceptional! (16 reviews)

Casa La Costa By Wynwood House

Casa La Costa By Wynwood House

3.5 out of 5
Casco Viejo
Price was $1,452, price is now $1,067 per person
$1,067
per person
Dec 23 - Dec 27
found 23 hours ago
Roundtrip flight included
Georgetown (GEO) to Panama City (PTY)
7.8/10 Good! (34 reviews)
The bed was fine, but the closet and the floor were quite dirty. There was also an unpleasant smell in my room.

Reviewed on Jul 25, 2026

Surfside Beachfront Suites by Playa Caracol Resorts

Surfside Beachfront Suites by Playa Caracol Resorts

3.5 out of 5
Price was $1,717, price is now $1,271 per person
$1,271
per person
Jan 4 - Jan 9
found 1 day ago
Roundtrip flight included
New York (NYC) to Panama City (PTY)
8.2/10 Very Good! (53 reviews)

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What to do in Santa Clara

Antón Valley Tours from Riu Playa Blanca, Rio hato

Antón Valley Tours from Riu Playa Blanca, Rio hato

$36
per adult
Antón Valley Tours from Riu Playa Blanca, Rio hato
Anton Valley

Valle De Anton Rainfall Hot Springs and Nature Private Tour

$95
per adult
Valle De Anton Rainfall Hot Springs and Nature Private Tour
White Sand

Private Beach Day in Santa Clara Pacific Ocean

$125
per adult
Private Beach Day in Santa Clara Pacific Ocean
See all activities in Santa Clara

Santa Clara Hotel Deals

Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Calle Central, 5 Rio Hato Cocle
$110 nightly
The price is $110 total per night from Nov 10 to Nov 11
$110 total
Nov 10 - Nov 11
Total with taxes and fees
9.8/10 Exceptional! (69 reviews)
"Christophe and his family were amazing hosts. The breakfast was incredible and fit for a king. The grounds, room and pool were decorated beautifully and very well maintained. We would stay here again in a heartbeat. We highly recommend this place."

Reviewed on Jun 17, 2026

Villa Botero By Casa Mojito B&B
Gran Evenia Bijao - All Inclusive

Gran Evenia Bijao - All Inclusive

3.5 out of 5
Carretera Interamericana km 108, guias de Anton Rio Hato Coclé
$192 nightly
The price is $211 total per night from Oct 29 to Oct 30
$211 total
Oct 29 - Oct 30
Total with taxes and fees
8.2/10 Very Good! (1,003 reviews)
"Enjoyed my stay and had a great time."

Reviewed on Oct 28, 2026

Gran Evenia Bijao - All Inclusive
Hotel Riu Playa Blanca - All Inclusive

Hotel Riu Playa Blanca - All Inclusive

3.5 out of 5
Finca 43.668 Rio Hato Cocle
Get rates
Hotel Riu Playa Blanca - All Inclusive
See all 508 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Clara Vacation Packages

Things to do near Santa Clara

Santa Clara offers a perfect blend of beach relaxation and outdoor fun, making it ideal for family vacations. Visitors can enjoy shopping at local centers and resorts, along with a variety of special events and attractions tailored for all ages. Be sure to check out the hours for splash activities that promise excitement for the whole family. With plenty to do, Santa Clara ensures a memorable experience for every traveler.

Shopping

In Santa Clara, explore the Sunday Market for local crafts and fresh produce. If you're up for a drive, visit Coronado Mall for shopping and entertainment, or head to Mercado de Artesanías La Pintada for unique artisan gifts and souvenirs.

Recreation

At La Casa de Lourdes Outdoor Spa, only 2 miles from Santa Clara, indulge in rejuvenating body treatments amidst serene surroundings. A bit further, Pozos Termales, located 15 miles away, offers soothing thermal baths for ultimate relaxation and wellness, providing a tranquil escape from daily life.

Adventure

Explore the Square Trees Nature Trail, a scenic hiking experience located 16 miles from Santa Clara. Immerse yourself in the vibrant outdoors, surrounded by unique flora and breathtaking views, perfect for nature enthusiasts and adventure seekers alike.

Nightlife

Santa Clara offers a vibrant nightlife with beachfront bars and lively lounges. Enjoy cocktails at the popular La Casa de Lourdes or dance the night away at the nearby El Toro. For a more laid-back evening, unwind with friends at local taverns and savor delicious seafood.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Santa Clara

Santa Clara in Rio Hato, Coclé, Panama, is the perfect destination for beach lovers and families seeking outdoor adventures. Visitors can enjoy a variety of attractions, including beautiful beaches, stunning waterfalls, and nearby islands. Whether you're looking for relaxation or an adventurous experience, Santa Clara offers something for everyone to create unforgettable memories.

  • Playa Blanca: A beautiful beach located 3 miles from Santa Clara, Playa Blanca offers a relaxing atmosphere with soft sands and vibrant beach vibes. Enjoy sunbathing, swimming, or beachside dining at nearby restaurants.
  • Farallon Island: Just 2 miles away, Farallon Island is a picturesque getaway featuring stunning beaches and outdoor activities. Explore its natural beauty, partake in snorkeling, or simply unwind in a tranquil setting.
  • Buenaventura Marina: Located 5 miles from Santa Clara, Buenaventura Marina is ideal for adventure seekers. Experience water sports, boat excursions, and stunning views, all while enjoying the perfect blend of outdoor, adventure, and beach vibes.

Best time to go to Santa Clara

The best time to visit Santa Clara can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Santa Clara falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature in Santa Clara falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.1°F (25.6°C)No RainMostly SunnySlightly HighSlightly High
February78.8°F (26.0°C)No RainSunnySlightly HighSlightly High
March79.5°F (26.4°C)No RainMostly SunnyAverageAverage
April80.4°F (26.9°C)Light RainMostly SunnyAverageAverage
May79.9°F (26.6°C)Moderate RainMostly CloudySlightly LowSlightly Low
June79.0°F (26.1°C)Frequent RainMostly CloudyAverageAverage
July78.6°F (25.9°C)Moderate RainMostly CloudySlightly HighAverage
August78.6°F (25.9°C)Frequent RainMostly CloudyAverageAverage
September78.4°F (25.8°C)Frequent RainMostly CloudySlightly LowSlightly Low
October77.5°F (25.3°C)Frequent RainMostly CloudySlightly LowSlightly Low
November77.2°F (25.1°C)Frequent RainMostly CloudyAverageAverage
December77.5°F (25.3°C)Light RainMostly SunnyAverageSlightly High

Tips to save on your trip to Santa Clara

  • Take advantage of package deals on Expedia and combine flights, hotels, or car rentals for a convenient and cost-effective trip to Santa Clara.
  • Consider traveling to Santa Clara during the low season (May and September to October) for more affordable options.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

Santa Clara Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Population
600
Max Temp Winter
85ºF
Max Temp Summer
85ºF
Top Sights
Parroquia Santiago Apóstol de Río Hato, Farallon Island and La Casa de Lourdes Outdoor Spa

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Frequently asked questions

What's included in a Santa Clara vacation package?
A Santa Clara vacation package lets you combine round-trip flights, hotel stays, and a rental car. Many packages feature hotels with direct beach access, allowing you to easily enjoy the coastline. Nearly all hotels in Santa Clara offer outdoor pools, and most also provide airport shuttle service, often to and from Rio Hato (RIH-Scarlett Martinez Intl.) Airport, with many also including free breakfast.

Exactly what's included will vary by hotel and package, so it's worth reviewing the details before you confirm your booking.
How can I save money on a Santa Clara vacation package?
When you bundle, you can save up to 30%*. To save money on a Santa Clara package, consider traveling during the quieter months or be flexible with your dates to find more options. Bundling your flights and hotel together often unlocks savings compared to booking separately. *Members only. Savings vary.
Is Santa Clara better suited for a beach vacation or a cultural trip?
Santa Clara is primarily a beach destination, with its long stretches of Pacific coastline making it ideal for a relaxing seaside escape. You'll find popular spots like Playa Blanca, about 4 miles from central Santa Clara, and Santa Clara Beach, which is about a 5-minute walk from the center.

While the focus for a Santa Clara vacation is often on the beaches, such as Farallón Beach about 2 miles away, there are also cultural points of interest like the Anton Valley Historical and Cultural Museum, about 4 miles from central Santa Clara. Your vacation package can be customized to balance beach time with local exploration.
What are the top things to do in Santa Clara?
A Santa Clara vacation offers plenty of opportunities to enjoy the Pacific coast and its surroundings:

Browse and book things to do in Santa Clara on Expedia.
Do you need to rent a car in Santa Clara, or is public transport enough?
For a Santa Clara vacation package, renting a car offers the most flexibility, especially if you plan to explore beyond your resort. While many resorts provide on-site dining and activities, a car allows you to easily visit other beaches or attractions like the Altos De Campana National Park, about 19 miles from central Santa Clara.

A rental car is generally recommended for travelers looking to maximize their exploration. When booking Santa Clara vacation packages with flights, consider adding a car rental for convenient travel from airports like Panama City (PTY-Tocumen Intl.) or Rio Hato (RIH-Scarlett Martinez Intl.).
Are there vacation package hotels in Santa Clara within walking distance of restaurants and shops?
Santa Clara vacation package hotels offer several options within walking distance of beaches, which often have nearby dining and shops.

For example, the 4-star Playa Blanca Beach Resort - All Inclusive and Town Center Paradise in Playa Blanca (rated 8.5 out of 10) are both about a 5-minute walk from Playa Blanca. Additionally, Villa Botero By Casa Mojito B&B, rated 9.3 out of 10, is about a 10-minute walk from Santa Clara Beach.

Actual walking routes may differ from straight-line distances, so check the map for your selected hotel.
Can I change or cancel my Santa Clara vacation package if my plans change?
Yes, you can cancel your vacation package via your itinerary page on Expedia or by contacting customer service. Remember that some packages are fully refundable, but the details vary based on each unique booking. A fully refundable package may depend on how far out from the travel dates you're canceling and what airline you are traveling with.
Do One Key members get extra savings when booking Santa Clara vacation packages?
Yes, members who join our free One Key™ travel rewards program can instantly unlock additional savings and save 10% or more on over 500,000 stays worldwide with Member Prices and over 1 million car rentals.
Does Expedia offer Book Now, Pay Later Santa Clara vacation packages?
Yes, with Expedia's Book Now, Pay Later option, powered by Affirm, you can spread the cost of your Santa Clara vacation over 3, 6, or 12 months. With no late payment fees or hidden costs, it's easy to secure your ideal vacation package as soon as you spot it.
How do I find last-minute vacation packages to Santa Clara?
To find last-minute vacation packages to Santa Clara, explore the last-minute deals section for the latest package offers, including flights, departing in the coming weeks. Being flexible with your travel dates and hotel preferences can help you secure the best prices.
How does free cancellation work on Santa Clara vacation packages?
Free cancellation on a Santa Clara vacation package depends on the specific hotel and rate combination you book. Many bookings allow free cancellation up to a stated deadline (often a few days before travel) where eligible. Read the cancellation terms carefully when reviewing the package, and visit Expedia help center for further details.
Is it cheaper to book a Santa Clara vacation as a package or separately?
Booking flights and hotels together can unlock lower overall prices. Better still, you can tailor your Santa Clara getaway to match your exact preference. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
Why should I book my Santa Clara vacation package with Expedia?
Booking your vacation package on Expedia makes it easier to get more out of your trip from the start. With a wide choice of hotels, you can compare prices, reviews and amenities all in one place, then bundle your hotel with flights which could help you save even more. Flexible booking options on selected stays also make it easier to plan with confidence.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.