Santa Clara Vacations from $740

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Your Santa Clara Vacation

Enjoy amazing adventures when you lock in a vacation package to Santa Clara. Whether you're a history buff, art enthusiast or just a traveler who loves discovering new places, there's something for everyone in this lively city. Every trip to Santa Clara needs a well-planned itinerary. Fill yours with big-name attractions like Farallon Island, La Casa de Lourdes Outdoor Spa and Parroquia Santiago Apóstol de Río Hato. Stop dreaming and start traveling. Explore the many options on Expedia today and put your Santa Clara vacation plans in motion!

The Latest Santa Clara vacation packages

Price found within the past 48 hours. Click for updated prices.
Casa Fofo
Villa Botero By Casa Mojito B&B
The Sands by Wynwood House
The Gray by Wynwood House
Central Hotel Bocas del Toro
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Discover the most popular places to visit in Santa Clara

What to do in Santa Clara

Santa Clara Hotel Deals

Villa Botero By Casa Mojito B&B
Villa Botero By Casa Mojito B&B
3 out of 5
Calle Central, 5, Rio Hato, Cocle
$110 nightly
The price is $110 total per night from Jul 15 to Jul 16
$110 total
Jul 15 - Jul 16
Total includes taxes and fees
9.6/10 Exceptional! (60 reviews)
"Wonderful little hotel. With only three"

Reviewed on Apr 21, 2025

Villa Botero By Casa Mojito B&B
Las Sirenas de Santa Clara
Las Sirenas de Santa Clara
3 out of 5
Carretera Interamericana Km.113, Rio Hato, Cocle
Excelente lugar para Familia - Enfocarse en eso!!
"Todo estuvo perfecto, solo pienso que si deben controlar un poco las personas que se hospedan en las cabañas, ejemplo: todas las cabañas que estábamos eramos familias con niños solo una donde todos eran jóvenes, esa cabaña tenia música y bulla hasta altas horas de la noche y aunque varios de las ..."

Reviewed on May 2, 2017

Las Sirenas de Santa Clara
Gran Evenia Bijao & Convention Center
Gran Evenia Bijao & Convention Center
3.5 out of 5
Carretera Interamericana km 108, Rio Hato
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $157 total per night from Jul 15 to Jul 16
$157 total
Jul 15 - Jul 16
Total includes taxes and fees
7.8/10 Good! (892 reviews)
"Very easy check in and out, Amazing staff great location and delicious food. The beds were comfortable. My kids really enjoyed the water slides and beach it was definitely worth the drive from the airport. My family and I really enjoyed the wildlife. We will definitely be back for a longer stay."

Reviewed on Jul 11, 2025

Gran Evenia Bijao & Convention Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Clara Vacation Packages

Santa Clara Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Population
600
Max Temp Winter
85ºF
Max Temp Summer
85ºF
Top Sights
Parroquia Santiago Apóstol de Río Hato, Farallon Island and La Casa de Lourdes Outdoor Spa

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Frequently asked questions

How much does a Santa Clara vacation package cost?
You'll find cheap prices from $740 on Expedia for your Santa Clara escape. However, factors like the length of stay, hotel choice and season will influence how much your vacation to Santa Clara costs.
What are the cheapest months to go to Santa Clara?
If you're hoping to book a cheap Santa Clara vacation package, consider traveling in January, July and December. You'll generally find lower prices on accommodations and flights during these quieter months --- ideal for travelers wishing to save money.
How many days is enough for Santa Clara?
The ideal length for your Santa Clara vacation depends on what you'd like to see and do. Typically, a handful of days to a week will give you plenty of time to go to all the leading sights and discover some hidden spots along the way.
How to find the best Santa Clara package deals?
Bagging a cheap Santa Clara package deal is a breeze with Expedia. After you've entered your destination and preferred dates under our "Packages" tab, set your budget, add a few filters and browse what's available. You can personalize your search by "Property class," "Number of bedrooms," "Traveler experience" and more. Sort the results by "Price: low to high" to discover the most economical Santa Clara package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are typically lower.
Is it cheaper to book a Santa Clara vacation as a package?
You can enjoy significant savings on your next Santa Clara getaway by booking a tailored vacation package. Click on the "Package" heading, then enter your travel dates and destination to view some great hotel and flight prices. Bundling can save travelers hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a vacation package to Santa Clara?
Score incredible bargains by booking your flights ahead of time with Expedia. If being spontaneous is more your thing, snap up one of our last-minute deals for a spur-of-the-moment Santa Clara vacation.
How to plan a trip to Santa Clara?

  1. Choose your travel dates: What you plan to do in Santa Clara and your preferred season can help you decide when to get away.
  2. Budget wisely: On top of the price of your hotel, you should factor in other expenses too. These include flights, food and transportation. Also, set aside some extra funds for unexpected costs that could arise during your trip to Santa Clara.
  3. Explore Santa Clara with Expedia's trip planning tool: Gain insights into the top attractions and best properties for your trip to Santa Clara. You can also save your favorite locations, collaborate with family and friends and manage all your plans in one place.
  4. Set the duration of your trip: Start by listing all the sights and activities you'd like to experience in Santa Clara. Then, estimate how long you'll need at each, including any travel time.
  5. Bundle your bookings: With your travel dates in place, you can combine your hotels, car rental, flights and more into a customized Santa Clara vacation package.
  6. Book experiences or activities in advance: Whether it's a ticket to a big attraction or a day trip, you won't have to worry about missing out on Santa Clara's best offerings. Find all the exciting things to do in Santa Clara with our dedicated travel guide.

Does Expedia offer Book Now, Pay Later Santa Clara vacation packages?
Jet off on your dream getaway to Santa Clara with Expedia's Book Now, Pay Later vacations. No need to save like crazy or wait for your next payday --- we've partnered with online lender Affirm to give you flexibility and choice. Our vacation packages with payment plans allow you to split the cost over 3, 6 or 12 months. With no late payment fees or hidden charges, it's easy to stay on budget and snap up travel deals before they sell out.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.