A coastal town with colorful buildings, a prominent church with a blue dome, and a clear blue sea.

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Check availability on Syros 5 Star Hotels

Tonight
Sep 1 - Sep 2
Tomorrow
Sep 2 - Sep 3
This weekend
Sep 4 - Sep 6
Next weekend
Sep 11 - Sep 13

Our top choices for Syros 5-star hotels

An infinity pool with clear blue water, a white infinity pool edge, and a view of the sea with boats.
A modern hotel room with a large bed, a sofa, two round wooden tables, a TV, and a view of the sea and buildings.
A beach with clear turquoise water, a boat, and a person paddleboarding.
A pathway leading to a rocky beach area with white pebbles and agave plants, overlooking the sea.

1. Myconian Ambassador Hotel Relais & Chateaux

Myconian Ambassador Hotel Relais & Chateaux
Mykonos
United States
Alexander
$261 nightly
$315 total
Sep 17 - Sep 18
Total with taxes and fees
Myconian Ambassador Hotel Relais & Chateaux
A poolside area with lounge chairs and a view of the sea at night.
A modern living room with a large rock feature, a white sofa, and a view of the sea.
A modern interior with a wooden floor, white furniture, a large window with a view of the sea, and a balcony with white chairs.
A modern bathroom with a large bathtub, wooden flooring, and a view of a cruise ship.

2. CAVO TAGOO MYKONOS

CAVO TAGOO MYKONOS
Mykonos
United States
Aryana
$625 nightly
$729 total
Oct 2 - Oct 3
Total with taxes and fees
CAVO TAGOO MYKONOS
An infinity pool with lounge chairs and a sunset view.
A corridor with a view of the sea and a distant mountain.
A cozy lounge area with a large arched window offering a scenic view of the sea and a sunset.
A round table with a vase and two glasses, overlooking a body of water and distant land.

3. Myconian Korali Relais & Chateaux

Myconian Korali Relais & Chateaux
Mykonos
Ireland
Peter
Myconian Korali Relais & Chateaux
A modern outdoor lounge area with a pool, seating, and a view of the sea.
A modern hotel room with a large bed, a desk, and a view of the ocean.
A woman in a white dress overlooking a coastal town with white buildings and boats in the harbor.
A modern room with a large window overlooking a body of water and a yacht. There is a sofa, a small round table, and a chair.

4. Myconian Deos - The Set

Myconian Deos - The Set
Mykonos
United States
Darryl
$484 nightly
$568 total
Oct 1 - Oct 2
Total with taxes and fees
Myconian Deos - The Set
A modern resort with a pool, stone walls, and outdoor seating areas.
A modern room with a large sliding glass door leading to an outdoor seating area with a view of the sea.
A bedroom with a large bed, wooden beams, a view of the sea, and a balcony.
A stone-walled outdoor area with a hot tub, a sofa with cushions, and a view of the sea.

5. Ovea Mykonos

Ovea Mykonos
Mykonos
Canada
angelica dayana arteaga
$114 nightly
$148 total
Oct 1 - Oct 2
Total with taxes and fees
Ovea Mykonos
A poolside view with a clear blue sea and a mountain in the distance.
An outdoor dining area with wooden tables and chairs, stone walls, and a view of the sea.
A spacious lobby with a polished marble floor, elegant sofas, and a grand chandelier.
A restaurant with tables and chairs arranged to face a large window overlooking a beach and ocean.

6. Saint John Hotel Villas & Spa

Saint John Hotel Villas & Spa
Mykonos
United States
Nicholas
$232 nightly
$282 total
Sep 21 - Sep 22
Total with taxes and fees
Saint John Hotel Villas & Spa
A swimming pool with a clear view of the water, a white poolside area, and two empty glasses on a white surface.
A spacious bedroom with a large bed, a bathroom with a large mirror, and a view of the sea.
A waterfront resort with outdoor seating, a pool, and boats in the background.
A modern building with a stone facade and a clear sky.

7. Nissaki Boutique Hotel

Nissaki Boutique Hotel
Mykonos
United States
Melissa
$217 nightly
$265 total
Sep 29 - Sep 30
Total with taxes and fees
Nissaki Boutique Hotel
A swimming pool with star-shaped lights at night.
A modern interior with a wooden partition, a chandelier, and a seating area with two white poufs.
A bedroom with a canopy bed, a wooden chair, and a view of the sea.

8. Palladium Hotel

Palladium Hotel
Mykonos
Spain
Filipe
$241 nightly
$292 total
Oct 2 - Oct 3
Total with taxes and fees
Palladium Hotel
A pool with clear blue water and white umbrellas.
A modern hotel room with a view of the ocean, a sitting area with a chair and a small table, and a large mirror on the wall.
A modern bedroom with a large bed, a bathtub, and a view of the sea.
A clear blue pool with a sailboat in the water and a distant shoreline.

9. Mykonos Riviera Hotel & Spa a member of Small Luxury Hotels of the World

Mykonos Riviera Hotel & Spa a member of Small Luxury Hotels of the World
Mykonos
Canada
Hamsa
$374 nightly
$443 total
Sep 17 - Sep 18
Total with taxes and fees
Mykonos Riviera Hotel & Spa a member of Small Luxury Hotels of the World
A pool area with a view of the sea, stone walls, and a hanging chair.
A modern hotel room with a large bed, a sofa, a flat-screen TV, and a view of the ocean.
A rooftop terrace with a wooden pergola, stone walls, a cushioned seating area, and a view of the ocean.
A multi-story hotel with stone architecture, a pool area with lounge chairs, and a view of rocky terrain.

10. Tropicana Suites & Villas

Tropicana Suites & Villas
Mykonos
United States
Azmira
$372 nightly
$441 total
Sep 11 - Sep 12
Total with taxes and fees
Tropicana Suites & Villas
A modern pool area with lounge chairs and umbrellas, a glass-enclosed bar, and a clear view of the sky.
A bar area with a stone wall backdrop, bar stools, and a large planter with a tree.
A modern, spacious room with a white sofa set, wicker chairs, and large windows offering a view of the sea.
A table set for dining with a view of the sea and a coastal town.

11. Myconian Kyma, a Member of Design Hotels

Myconian Kyma, a Member of Design Hotels
Mykonos
United States
David
Myconian Kyma, a Member of Design Hotels
A pool area with stone walls and palm trees, leading to a view of the sea.
A modern bedroom with a large bed, a sitting area, a bathtub, and a view of the sea.
A modern outdoor space with a stone wall, a black bathtub, and a seating area with a plant.
A restaurant with multiple tables and chairs, large windows offering a view of a cityscape and water at night.

12. Aeonic Suites and Spa

Aeonic Suites and Spa
Mykonos
United States
Mehmet
$322 nightly
$384 total
Sep 25 - Sep 26
Total with taxes and fees
Aeonic Suites and Spa
A white and blue room with a pool, a white chair, a blue table, and a white umbrella.
An open-plan restaurant with wooden furniture and large windows offering a view of the landscape.
A spacious living area with a wooden ceiling, white sofas, a central coffee table, and potted plants.
A white building with a red roof, a cross on top, and a large bougainvillea tree in front.

13. San Antonio Summerland

San Antonio Summerland
Mykonos
United States
Charles Edward
$154 nightly
$193 total
Oct 2 - Oct 3
Total with taxes and fees
San Antonio Summerland
A stone-walled balcony with a round table, a vase with dried plants, and a view of the sea and distant hills.
A pool area with a view of the sea and a hillside.
A cozy room with a stone wall, a cushioned bench, a vase with dried flowers, and a wooden stool.
A coastal hotel with a swimming pool, multiple buildings, and a view of the sea.

14. Mykonos Theoxenia, a Member of Design Hotels

Mykonos Theoxenia, a Member of Design Hotels
Mykonos
Australia
John
$457 nightly
$538 total
Sep 17 - Sep 18
Total with taxes and fees
Mykonos Theoxenia, a Member of Design Hotels
A poolside dining area with a table set for two, overlooking a pool with a view of the sea and distant hills.
A modern hotel room with a bed, a sofa, a desk, and a TV.
A hotel room with a large bed, a desk, a chair, and a TV. There are large windows with a view of the sea.
A rooftop lounge area with sun loungers, a large tree, and a view of the sea.

15. Grace Mykonos

Grace Mykonos
Mykonos
United States
Lindita
$212 nightly
$259 total
Oct 1 - Oct 2
Total with taxes and fees
Grace Mykonos
A pool with a view of the sea and mountains, a yacht in the distance, and a cactus garden.
A sunlit outdoor seating area with stone walls, a wooden bench, and a table with a bowl and cup.
A modern interior with a large window offering a coastal view, a wooden table, a cushioned chair, and a fireplace.
A beach with lounge chairs and umbrellas, a woman in a swimsuit walking, and clear blue water.

16. Bill&Coo Mykonos

Bill&Coo Mykonos
Mykonos
Canada
Matthew
$410 nightly
$484 total
Oct 2 - Oct 3
Total with taxes and fees
Bill&Coo Mykonos
A poolside area with lounge chairs and a view of the sea.
A hotel room with a bed, a chair, a nightstand, a lamp, and a view of the sea.
A poolside area with two lounge chairs and an umbrella, overlooking a calm sea with boats and a hilly landscape in the background.
A resort with a central swimming pool, lounge areas, and a patio with outdoor seating.

17. Kalesma Mykonos

Kalesma Mykonos
Mykonos
United States
Giovanis
$536 nightly
$627 total
Sep 24 - Sep 25
Total with taxes and fees
Kalesma Mykonos
A rooftop pool area with seating and a view of the city.
A modern living room with a sofa, patterned cushions, and wall-mounted lights.
A modern room with a large window overlooking a pool and a scenic view. There is a dining table with a bottle and a book, and a sofa with cushions.
A modern bedroom with a large bed, a TV, and a view of the sea.

18. Nomia Sunset Suites Mykonos

Nomia Sunset Suites Mykonos
Mykonos
Canada
carol
$299 nightly
$358 total
Sep 17 - Sep 18
Total with taxes and fees
Nomia Sunset Suites Mykonos
A serene pool area with a clear view of the mountains, modern outdoor seating, and a well-lit building.
A modern living room with a large arched window, comfortable seating, and decorative elements.
A modern building with a sign reading "MYCONIAN NAIA LUXURY SUITES". Inside, there are multiple seating areas with chairs and tables.
A modern building with a stone facade, a wooden lattice entrance, and a well-lit interior.

19. Myconian Naia - Preferred Hotels & Resorts

Myconian Naia - Preferred Hotels & Resorts
Mykonos
United States
yaser
$402 nightly
$475 total
Sep 16 - Sep 17
Total with taxes and fees
Myconian Naia - Preferred Hotels & Resorts
A modern infinity pool with a woman meditating, a glass fireplace, and a view of the sea.
A sunlit outdoor lounge area with a view of the sea, wooden steps leading to a hot tub, and lounge chairs with cushions.
A modern lounge area with a bar, seating, and a view of the sea.
A modern bar area with a bartender, white bar stools, and a view of the sea.

20. Mykonos Grand Hotel & Resort

Mykonos Grand Hotel & Resort
Mykonos
United States
Ian
$413 nightly
$488 total
Sep 17 - Sep 18
Total with taxes and fees
Mykonos Grand Hotel & Resort
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Syros.
Petasos Beach Resort & Spa, Small Luxury Hotels of the World

Petasos Beach Resort & Spa, Small Luxury Hotels of the World

Platis Yialos Mykonos Mykonos Island
$246 nightly
$291 total
Sep 21 - Sep 22
Total with taxes and fees
9.6/10 Exceptional! (371 reviews)
Petasos Beach Resort & Spa, Small Luxury Hotels of the World
Poseidon Hotel & Suites

Poseidon Hotel & Suites

Mykonos Town Mykonos Mykonos Island
$151 nightly
$184 total
Oct 1 - Oct 2
Total with taxes and fees
Poseidon Hotel & Suites
Hermes Mykonos Hotel

Hermes Mykonos Hotel

Mykonos Town Mykonos Mykonos Island
$161 nightly
$195 total
Sep 29 - Sep 30
Total with taxes and fees
9.6/10 Exceptional! (981 reviews)
Hermes Mykonos Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Syros

Wander through Ermoupoli's neoclassical buildings and marble squares before catching a performance at the historic Apollo Theater. Swim at Galissas beach, then climb the hill to Ano Syros where medieval streets offer spectacular views across the Aegean.

See all hotels in Syros
A cobblestone street lined with colorful buildings, a prominent yellow church with a blue dome, and a clear blue sky.

Top Syros Hotel Reviews

Tropicana Suites & Villas

Tropicana Suites & Villas

10/10 Excellent
"Clean room, the best staff"
Fedora 4-night trip
Posted 3 hours ago
Tropicana Suites & Villas
Myconian Korali Relais & Chateaux

Myconian Korali Relais & Chateaux

8/10 Good
"Everywhere was SPOTLESS, could eat your dinner off the floor. Staffamazing from the cleaning ladies and attendants to all the waitresses and receptionists. Breakfast had a lot of choice so nothing to complain about"
Zehra 4-night trip
Posted 3 hours ago
Myconian Korali Relais & Chateaux
Nissaki Boutique Hotel

Nissaki Boutique Hotel

8/10 Good
"This place was very nice and well managed and maintained. The staff was very helpful."
Katrina 3-night trip
Posted 11 days ago
Nissaki Boutique Hotel

Find out more about Syros

Ready to experience the next standard in luxury? We know you're thinking about it. Add even more pleasure on your next trip to Syros by treating yourself to the best of the best when it comes to lodging. It's an ideal pairing. There's no reason to delay a getaway to Syros any longer. You'll join the multitudes of vacationers who have made Syros so fashionable in the last few seasons. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. You deserve an outstanding getaway. Book one of Expedia's luxurious 5-star hotels in Syros and get ready to be pampered like never before.

5-Star Hotels in Syros

You'll have a fantastic time at one of these 5-star hotels. High-end restaurants, excellent customer care, and rejuvenating spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also look forward to an outstanding experience and fantastic customer care, so get ready to kick back and indulge. What kind of amenities will make your stay a wonderful one? A mud wrap treatment that will leave you feeling refreshed and alive? 24-hour room service, so you can order that Turkish coffee in the wee hours of the morning? A full-body massage to help your cares fall away?

But you aren't going to spend your entire vacation in your room, of course. We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Syros are waiting for you to relax after an exciting day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs.

Make Your Escape

The results are in, and Syros 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Don't put off your dream vacation any longer -- this is a great time to find 5-star hotel deals in @region! Select one of the 5-star hotels in Syros today and decompress in total tranquility when you're ready.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Syros?
The amount you pay for a 5-star hotel in Syros depends on factors like when you plan to go and the length of your trip. A top tip for bagging an awesome deal? Use our pricing filters to check out the available hotels for your selected dates.
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What makes a hotel 5 stars in Syros?
From gourmet dining venues and all-day gyms to pools and dreamy bedding, the 5-star experience in Syros is all about indulgence and comfort. But it requires more than just upscale perks to get a 5-star rating. Accommodations also have to offer exceptional services like massage treatments, laundry and dry cleaning and a nightly turn-down service.
Are there any 5-star all-inclusive resorts in Syros?
Our handy filters are the easiest way to find exactly what you're looking for. Select "All inclusive" and "5-star" to show the finest resorts in Syros where your meals, lodging, activities and entertainment are included in the price. At these escapes, your vacation is pure leisure from the moment you step foot in the lobby.

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