A coastal town with colorful buildings, a prominent church with a blue dome, and a clear blue sea.

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Check availability on Syros 5 Star Hotels

Tonight
Oct 1 - Oct 2
Tomorrow
Oct 2 - Oct 3
This weekend
Oct 2 - Oct 4
Next weekend
Oct 9 - Oct 11

Our top choices for Syros 5-star hotels

A poolside area with lounge chairs and a view of the sea at night.
A modern bathroom with a large bathtub, wooden flooring, and a view of a cruise ship.
A modern interior with a wooden floor, white furniture, a large window with a view of the sea, and a balcony with white chairs.
A modern living room with a large rock feature, a white sofa, and a view of the sea.

1. CAVO TAGOO MYKONOS

CAVO TAGOO MYKONOS
Mykonos
United Arab Emirates
Balqees
$582 nightly
$679 total
Oct 9 - Oct 10
Total with taxes and fees
CAVO TAGOO MYKONOS
A modern outdoor lounge area with a pool, seating, and a view of the sea.
A modern hotel room with a large bed, a desk, and a view of the ocean.
A modern outdoor staircase with integrated lighting, surrounded by potted plants and large vases.
A modern room with a large window overlooking a body of water and a yacht. There is a sofa, a small round table, and a chair.

2. Myconian Deos - The Set

Myconian Deos - The Set
Mykonos
United States
Gisela
$400 nightly
$472 total
Oct 24 - Oct 25
Total with taxes and fees
Myconian Deos - The Set
An infinity pool with clear blue water, a white infinity pool edge, and a view of the sea with boats.
A pathway leading to a rocky beach area with white pebbles and agave plants, overlooking the sea.
A modern hotel room with a large bed, a sofa, two round wooden tables, a TV, and a view of the sea and buildings.
A person lounging on a cushioned outdoor seating area with a view of the sea and a distant rocky island.

3. Myconian Ambassador Hotel Relais & Chateaux

Myconian Ambassador Hotel Relais & Chateaux
Mykonos
United States
Scott
$173 nightly
$214 total
Oct 30 - Oct 31
Total with taxes and fees
Myconian Ambassador Hotel Relais & Chateaux
An infinity pool with lounge chairs and a sunset view.
A round table with a vase and two glasses, overlooking a body of water and distant land.
A corridor with a view of the sea and a distant mountain.
A cozy lounge area with a large arched window offering a scenic view of the sea and a sunset.

4. Myconian Korali Relais & Chateaux

Myconian Korali Relais & Chateaux
Mykonos
United Kingdom
Christopher
$205 nightly
$250 total
Oct 8 - Oct 9
Total with taxes and fees
Myconian Korali Relais & Chateaux
A pool area with a view of the sea, stone walls, and a hanging chair.
A multi-story hotel with stone architecture, a pool area with lounge chairs, and a view of rocky terrain.
A coastal beach with clear turquoise waters, a sandy shore, and several boats.
A modern hotel room with a large bed, a sofa, a flat-screen TV, and a view of the ocean.

5. Tropicana Suites & Villas

Tropicana Suites & Villas
Mykonos
Canada
Cameron
$416 nightly
$490 total
Oct 3 - Oct 4
Total with taxes and fees
Tropicana Suites & Villas
A swimming pool with star-shaped lights at night.
A bedroom with a canopy bed, a wooden chair, and a view of the sea.
A modern interior with a wooden partition, a chandelier, and a seating area with two white poufs.
A marina with multiple yachts docked, rocky coastline, and buildings on the right.

6. Palladium Hotel

Palladium Hotel
Mykonos
United States
Edmond
$145 nightly
$182 total
Oct 16 - Oct 17
Total with taxes and fees
Palladium Hotel
A modern outdoor pool area with lounge chairs and a fire feature.
A modern, multi-level bedroom with a built-in hot tub, white blinds, and a stone wall backdrop.
A spacious living room with a sectional sofa, two armchairs, a glass coffee table, and large windows with white shutters.
A restaurant setting with tables set for dining, featuring candlelight and hanging lamps.

7. Semeli Hotel

Semeli Hotel
Mykonos
United States
Sonki
$179 nightly
$220 total
Oct 5 - Oct 6
Total with taxes and fees
Semeli Hotel
A swimming pool with a clear view of the water, a white poolside area, and two empty glasses on a white surface.
A modern building with a stone facade and a clear sky.
A waterfront resort with outdoor seating, a pool, and boats in the background.
A spacious indoor area with a high ceiling, modern chandeliers, and a view of the sea through large windows.

8. Nissaki Boutique Hotel

Nissaki Boutique Hotel
Mykonos
United States
Melissa
$223 nightly
$271 total
Oct 2 - Oct 3
Total with taxes and fees
Nissaki Boutique Hotel
A pool with a view of the sea and mountains, a yacht in the distance, and a cactus garden.
A modern interior with a large window offering a coastal view, a wooden table, a cushioned chair, and a fireplace.
A beach with lounge chairs and umbrellas, a woman in a swimsuit walking, and clear blue water.
A sunlit outdoor seating area with stone walls, a wooden bench, and a table with a bowl and cup.

9. Bill&Coo Mykonos

Bill&Coo Mykonos
Mykonos
Canada
Matthew
$317 nightly
$377 total
Oct 6 - Oct 7
Total with taxes and fees
Bill&Coo Mykonos
A pool with clear blue water and white umbrellas.
A modern bedroom with a large bed, a bathtub, and a view of the sea.
A modern hotel room with a view of the ocean, a sitting area with a chair and a small table, and a large mirror on the wall.
A seaside dining area with a table set for two, overlooking a coastal town.

10. Mykonos Riviera Hotel & Spa a member of Small Luxury Hotels of the World

Mykonos Riviera Hotel & Spa a member of Small Luxury Hotels of the World
Mykonos
United States
Alesia
$334 nightly
$398 total
Oct 2 - Oct 3
Total with taxes and fees
Mykonos Riviera Hotel & Spa a member of Small Luxury Hotels of the World
A resort with multiple swimming pools, a beach area with umbrellas, and boats in the water.
A pool with a curved edge, a white building with arches, and a view of the sea with a sailboat.
A bedroom with a bed, a desk, and a view of the ocean.
View from property

11. Mykonos Blu, A Resort to Live

Mykonos Blu, A Resort to Live
Mykonos
United States
Hagop
$329 nightly
$392 total
Oct 5 - Oct 6
Total with taxes and fees
Mykonos Blu, A Resort to Live
A white and blue room with a pool, a white chair, a blue table, and a white umbrella.
An open-plan restaurant with wooden furniture and large windows offering a view of the landscape.
A white building with a red roof, a cross on top, and a large bougainvillea tree in front.
A spacious living area with a wooden ceiling, white sofas, a central coffee table, and potted plants.

12. San Antonio Summerland

San Antonio Summerland
Mykonos
United States
Charles Edward
$178 nightly
$219 total
Oct 4 - Oct 5
Total with taxes and fees
San Antonio Summerland
A pool area with stone walls and palm trees, leading to a view of the sea.
A modern bathroom with a large window, a bathtub, a towel, and a tray with food items.
A modern bedroom with a large bed, a sitting area, a bathtub, and a view of the sea.
A modern outdoor space with a stone wall, a black bathtub, and a seating area with a plant.

13. Aeonic Suites and Spa

Aeonic Suites and Spa
Mykonos
United States
Lester
$367 nightly
$434 total
Oct 7 - Oct 8
Total with taxes and fees
Aeonic Suites and Spa
A modern outdoor lounge area with a pool, wooden pergola, and hanging chairs.
A beach with yellow and white umbrellas, a sandy area, and a view of the sea and distant mountains.
A beachside restaurant with wicker furniture, stone pillars, and umbrellas overlooking the sea.
A bar area with wicker chairs, wooden tables, and pendant lighting.

14. Santa Marina, a Luxury Collection Resort, Mykonos

Santa Marina, a Luxury Collection Resort, Mykonos
Mykonos
United Kingdom
FLORENCE
$554 nightly
$648 total
Oct 15 - Oct 16
Total with taxes and fees
Santa Marina, a Luxury Collection Resort, Mykonos
A poolside area with lounge chairs and a view of the sea.
A poolside area with two lounge chairs and an umbrella, overlooking a calm sea with boats and a hilly landscape in the background.
A hotel room with a bed, a chair, a nightstand, a lamp, and a view of the sea.
A bar area with a view of the sea and a hillside.

15. Kalesma Mykonos

Kalesma Mykonos
Mykonos
United States
Neal
$587 nightly
$685 total
Oct 4 - Oct 5
Total with taxes and fees
Kalesma Mykonos
A calm body of water reflecting the sky during sunset.
A seaside terrace with a stone wall, a wooden pergola, and a view of a coastal town.
A bedroom with a large window overlooking a coastal landscape, a bed, a chair, and a small table with a vase.
A modern bar area with a view of the water, wooden furniture, and unique light fixtures.

16. Amazon Mykonos Resort & Spa

Amazon Mykonos Resort & Spa
Mykonos
United States
Mahsa
$218 nightly
$265 total
Oct 3 - Oct 4
Total with taxes and fees
Amazon Mykonos Resort & Spa
A modern hotel with a swimming pool, sun loungers, and a helipad.
A table with a clear glass, a rolled-up blueprint, and a white cup with a logo, overlooking a coastal view.
A table set with wine glasses, plates of food, and a view of the sea.
A windmill with a white building in the background.

17. Absolute Mykonos Suites & More

Absolute Mykonos Suites & More
Mykonos
United States
Michael
$297 nightly
$355 total
Oct 5 - Oct 6
Total with taxes and fees
Absolute Mykonos Suites & More
A modern building with a pool, set against a rocky coastline and the sea.
A stone building with a flat roof and a large open doorway.
A modern interior with a water feature, large rocks, and a minimalist design.
A modern building with multiple levels and balconies, surrounded by large rocks.

18. Armacaas Mykonos Hotel

Armacaas Mykonos Hotel
Mykonos
United States
Yarleny
$154 nightly
$192 total
Oct 2 - Oct 3
Total with taxes and fees
Armacaas Mykonos Hotel
A serene pool area with a clear view of the mountains, modern outdoor seating, and a well-lit building.
A modern building with a sign reading "MYCONIAN NAIA LUXURY SUITES". Inside, there are multiple seating areas with chairs and tables.
A modern building with a stone facade, a wooden lattice entrance, and a well-lit interior.
A room with a view of the sea, a round table, two chairs, and a ceiling with wooden slats.

19. Myconian Naia - Preferred Hotels & Resorts

Myconian Naia - Preferred Hotels & Resorts
Mykonos
United States
shahram
Myconian Naia - Preferred Hotels & Resorts
A luxurious outdoor dining area with wicker chandeliers, palm trees, and a pool overlooking a marina.
A seaside restaurant with wicker furniture, tables set with glasses and plates, and umbrellas providing shade.
A bar area with wicker chairs and a poolside seating area.
An aerial view of a beachside hotel with rows of sun loungers and palm trees.

20. O by Myconian, Mykonos, a Member of Design Hotels

O by Myconian, Mykonos, a Member of Design Hotels
Mykonos
United States
Sahar
$343 nightly
$408 total
Oct 4 - Oct 5
Total with taxes and fees
O by Myconian, Mykonos, a Member of Design Hotels
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Syros.
Poseidon Hotel & Suites

Poseidon Hotel & Suites

Mykonos Town Mykonos Mykonos Island
$146 nightly
$177 total
Oct 2 - Oct 3
Total with taxes and fees
9.6/10 Exceptional! (1,000 reviews)
Poseidon Hotel & Suites
Hermes Mykonos Hotel

Hermes Mykonos Hotel

Mykonos Town Mykonos Mykonos Island
$125 nightly
$154 total
Oct 2 - Oct 3
Total with taxes and fees
9.6/10 Exceptional! (991 reviews)
Hermes Mykonos Hotel
Giannoulaki Hotel

Giannoulaki Hotel

Glastros Mykonos Mykonos Island
Get ratesGiannoulaki Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Syros

Wander through Ermoupoli's neoclassical buildings and marble squares before catching a performance at the historic Apollo Theater. Swim at Galissas beach, then climb the hill to Ano Syros where medieval streets offer spectacular views across the Aegean.

See all hotels in Syros
A cobblestone street lined with colorful buildings, a prominent yellow church with a blue dome, and a clear blue sky.

Top Syros Hotel Reviews

Myconian Korali Relais & Chateaux

Myconian Korali Relais & Chateaux

10/10 Excellent
"The hotel was great and all the staff were very helpful. It was a little weird at the last day when the reception team asked if we wanted to add a tip of 10% on the whole stay for the reception team."
Kieran 8-night trip
Posted 9 hours ago
Myconian Korali Relais & Chateaux
CAVO TAGOO MYKONOS

CAVO TAGOO MYKONOS

10/10 Excellent
"The room was not properly prepared for 5 star rated. The pool lounge bed coverings was hanging off and the hostess said it was the wind but for a excellent rating and with the luxury price everything should be better prepared for first impression"
Travis 1-night trip
Posted 15 hours ago
CAVO TAGOO MYKONOS
Tropicana Suites & Villas

Tropicana Suites & Villas

10/10 Excellent
"It was wonderful. We enjoyed every moment on this beautiful place , the services , the staff were fantastic, everything was so clean . We loved it! I highly recommend!"
Lucas 6-night trip
Posted 19 hours ago
Tropicana Suites & Villas
Myconian Deos - The Set

Myconian Deos - The Set

10/10 Excellent
"This is the place to stay if you want beauty, pampering and great location. Will definitely return. Views amazing, hotel gorgeous."
suzanne 3-night trip
Posted 3 days ago
Myconian Deos - The Set

Find out more about Syros

Ready to experience the next standard in luxury? We know you're thinking about it. Add even more pleasure on your next trip to Syros by treating yourself to the best of the best when it comes to lodging. It's an ideal pairing. There's no reason to delay a getaway to Syros any longer. You'll join the multitudes of vacationers who have made Syros so fashionable in the last few seasons. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. You deserve an outstanding getaway. Book one of Expedia's luxurious 5-star hotels in Syros and get ready to be pampered like never before.

5-Star Hotels in Syros

You'll have a fantastic time at one of these 5-star hotels. High-end restaurants, excellent customer care, and rejuvenating spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also look forward to an outstanding experience and fantastic customer care, so get ready to kick back and indulge. What kind of amenities will make your stay a wonderful one? A mud wrap treatment that will leave you feeling refreshed and alive? 24-hour room service, so you can order that Turkish coffee in the wee hours of the morning? A full-body massage to help your cares fall away?

But you aren't going to spend your entire vacation in your room, of course. We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Syros are waiting for you to relax after an exciting day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs.

Make Your Escape

The results are in, and Syros 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Don't put off your dream vacation any longer -- this is a great time to find 5-star hotel deals in @region! Select one of the 5-star hotels in Syros today and decompress in total tranquility when you're ready.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Syros?
The amount you pay for a 5-star hotel in Syros depends on factors like when you plan to go and the length of your trip. A top tip for bagging an awesome deal? Use our pricing filters to check out the available hotels for your selected dates.
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What makes a hotel 5 stars in Syros?
From gourmet dining venues and all-day gyms to pools and dreamy bedding, the 5-star experience in Syros is all about indulgence and comfort. But it requires more than just upscale perks to get a 5-star rating. Accommodations also have to offer exceptional services like massage treatments, laundry and dry cleaning and a nightly turn-down service.
Are there any 5-star all-inclusive resorts in Syros?
Our handy filters are the easiest way to find exactly what you're looking for. Select "All inclusive" and "5-star" to show the finest resorts in Syros where your meals, lodging, activities and entertainment are included in the price. At these escapes, your vacation is pure leisure from the moment you step foot in the lobby.

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