A coastal town with colorful buildings, a prominent church with a blue dome, and a clear blue sea.

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Check availability on Syros 5 Star Hotels

Tonight
Sep 9 - Sep 10
Tomorrow
Sep 10 - Sep 11
This weekend
Sep 11 - Sep 13
Next weekend
Sep 18 - Sep 20

Our top choices for Syros 5-star hotels

A poolside area with lounge chairs and a view of the sea at night.
A modern, white-themed living room with a dining area, large windows offering a view of the sea, and a minimalist design.
A modern bathroom with a large bathtub, wooden flooring, and a view of a cruise ship.
A modern interior with a wooden floor, white furniture, a large window with a view of the sea, and a balcony with white chairs.

1. CAVO TAGOO MYKONOS

CAVO TAGOO MYKONOS
Mykonos
United States
Aryana
$696 nightly
$810 total
Oct 3 - Oct 4
Total with taxes and fees
CAVO TAGOO MYKONOS
A modern outdoor lounge area with a pool, seating, and a view of the sea.
A woman in a white dress overlooking a coastal town with white buildings and boats in the harbor.
A modern hotel room with a large bed, a desk, and a view of the ocean.
A modern room with a large window overlooking a body of water and a yacht. There is a sofa, a small round table, and a chair.

2. Myconian Deos - The Set

Myconian Deos - The Set
Mykonos
United States
Darryl
$426 nightly
$502 total
Oct 9 - Oct 10
Total with taxes and fees
Myconian Deos - The Set
An infinity pool with lounge chairs and a sunset view.
A round table with a vase and two glasses, overlooking a body of water and distant land.
A corridor with a view of the sea and a distant mountain.
A modern hotel room with a large bed, a flat-screen TV, a ceiling light, and a view of the outdoors.

3. Myconian Korali Relais & Chateaux

Myconian Korali Relais & Chateaux
Mykonos
Ireland
Peter
$210 nightly
$257 total
Oct 10 - Oct 11
Total with taxes and fees
Myconian Korali Relais & Chateaux
An infinity pool with clear blue water, a white infinity pool edge, and a view of the sea with boats.
A person lounging on a cushioned outdoor seating area with a view of the sea and a distant rocky island.
A pathway leading to a rocky beach area with white pebbles and agave plants, overlooking the sea.
A modern hotel room with a large bed, a sofa, two round wooden tables, a TV, and a view of the sea and buildings.

4. Myconian Ambassador Hotel Relais & Chateaux

Myconian Ambassador Hotel Relais & Chateaux
Mykonos
Canada
Rebecca
$178 nightly
$220 total
Oct 9 - Oct 10
Total with taxes and fees
Myconian Ambassador Hotel Relais & Chateaux
A swimming pool with star-shaped lights at night.
A modern interior with a wooden partition, a chandelier, and a seating area with two white poufs.
A marina with multiple yachts docked, rocky coastline, and buildings on the right.
A bedroom with a bed, a hanging lamp, a view of a pool, and a seating area with cushions and a bowl of fruit.

5. Palladium Hotel

Palladium Hotel
Mykonos
Spain
Filipe
$216 nightly
$263 total
Oct 1 - Oct 2
Total with taxes and fees
Palladium Hotel
A pool with clear blue water and white umbrellas.
A modern hotel room with a view of the ocean, a sitting area with a chair and a small table, and a large mirror on the wall.
A seaside dining area with a table set for two, overlooking a coastal town.
A modern bedroom with a large bed, a bathtub, and a view of the sea.

6. Mykonos Riviera Hotel & Spa a member of Small Luxury Hotels of the World

Mykonos Riviera Hotel & Spa a member of Small Luxury Hotels of the World
Mykonos
Finland
Joel Olli Paavali
$347 nightly
$413 total
Sep 18 - Sep 19
Total with taxes and fees
Mykonos Riviera Hotel & Spa a member of Small Luxury Hotels of the World
A resort with multiple swimming pools, a beach area with umbrellas, and boats in the water.
A sunlit outdoor seating area with white furniture, a wooden coffee table, and a view of the sea with yachts.
A bedroom with a bed, a desk, and a view of the ocean.

7. Mykonos Blu, A Resort to Live

Mykonos Blu, A Resort to Live
Mykonos
United States
Hagop
$346 nightly
$411 total
Oct 1 - Oct 2
Total with taxes and fees
Mykonos Blu, A Resort to Live
A modern outdoor pool area with lounge chairs and a fire feature.
A restaurant setting with tables set for dining, featuring candlelight and hanging lamps.
A spacious living room with a sectional sofa, two armchairs, a glass coffee table, and large windows with white shutters.
An outdoor patio with a modern design, featuring a glass ceiling, seating areas, and a dining setup.

8. Semeli Hotel

Semeli Hotel
Mykonos
United States
Leah
$195 nightly
$239 total
Oct 2 - Oct 3
Total with taxes and fees
Semeli Hotel
A pool area with a view of the sea, stone walls, and a hanging chair.
A modern hotel room with a large bed, a sofa, a flat-screen TV, and a view of the ocean.
A multi-story hotel with stone architecture, a pool area with lounge chairs, and a view of rocky terrain.
A coastal beach with clear turquoise waters, a sandy shore, and several boats.

9. Tropicana Suites & Villas

Tropicana Suites & Villas
Mykonos
United States
Azmira
$372 nightly
$441 total
Sep 13 - Sep 14
Total with taxes and fees
Tropicana Suites & Villas
A swimming pool with a clear view of the water, a white poolside area, and two empty glasses on a white surface.
A spacious bedroom with a large bed, a bathroom with a large mirror, and a view of the sea.
A spacious indoor area with a high ceiling, modern chandeliers, and a view of the sea through large windows.
A modern building with a stone facade and a clear sky.

10. Nissaki Boutique Hotel

Nissaki Boutique Hotel
Mykonos
United States
Melissa
$165 nightly
$205 total
Oct 6 - Oct 7
Total with taxes and fees
Nissaki Boutique Hotel
A pool with a view of the sea and mountains, a yacht in the distance, and a cactus garden.
A sunlit outdoor seating area with stone walls, a wooden bench, and a table with a bowl and cup.
A modern interior with a large window offering a coastal view, a wooden table, a cushioned chair, and a fireplace.
A view from a window of a room with a wooden ceiling, a stone wall, and a poolside area with a table and chairs.

11. Bill&Coo Mykonos

Bill&Coo Mykonos
Mykonos
Canada
Matthew
$421 nightly
$497 total
Oct 5 - Oct 6
Total with taxes and fees
Bill&Coo Mykonos
A white and blue room with a pool, a white chair, a blue table, and a white umbrella.
A white building with a red roof, a cross on top, and a large bougainvillea tree in front.
An open-plan restaurant with wooden furniture and large windows offering a view of the landscape.
A bedroom with a bed, a desk, a chair, a television, and a view of the outside.

12. San Antonio Summerland

San Antonio Summerland
Mykonos
United States
Charles Edward
$156 nightly
$195 total
Sep 28 - Sep 29
Total with taxes and fees
San Antonio Summerland
A poolside area with lounge chairs, umbrellas, and boats.
A modern multi-level residential building with multiple swimming pools, outdoor seating areas, and a rooftop garden.
A modern living room with a wooden coffee table, two potted plants, a striped sofa, and a striped pillow.
A modern bedroom with a large bed, a view of boats and a coastal landscape through a sliding door, and a small table with a chair.

13. Once in Mykonos - Designed for Adults

Once in Mykonos - Designed for Adults
Mykonos
United States
Dmitry
$292 nightly
$350 total
Oct 7 - Oct 8
Total with taxes and fees
Once in Mykonos - Designed for Adults
A poolside view with a clear blue sea and a mountain in the distance.
A spacious lobby with a polished marble floor, elegant sofas, and a grand chandelier.
A coastal landscape with clear turquoise waters, rocky shoreline, and a sandy beach.
A restaurant with tables and chairs arranged to face a large window overlooking a beach and ocean.

14. Saint John Hotel Villas & Spa

Saint John Hotel Villas & Spa
Mykonos
United States
Nicholas
$181 nightly
$224 total
Oct 5 - Oct 6
Total with taxes and fees
Saint John Hotel Villas & Spa
A poolside dining area with a table set for two, overlooking a pool with a view of the sea and distant hills.
A rooftop lounge area with sun loungers, a large tree, and a view of the sea.
A coastal view with a clear blue sea, a sandy beach, and a distant hill with buildings.
A modern hotel room with a bed, a sofa, a desk, and a TV.

15. Grace Mykonos

Grace Mykonos
Mykonos
United States
Lindita
$203 nightly
$248 total
Oct 5 - Oct 6
Total with taxes and fees
Grace Mykonos
A rooftop pool area with seating and a view of the city.
A modern room with a large window overlooking a pool and a scenic view. There is a dining table with a bottle and a book, and a sofa with cushions.
A modern bedroom with a large bed, a TV, and a view of the sea.
A modern bedroom with a large bed, a small sofa, and a view of the sea.

16. Nomia Sunset Suites Mykonos

Nomia Sunset Suites Mykonos
Mykonos
United States
Michael
$254 nightly
$307 total
Sep 23 - Sep 24
Total with taxes and fees
Nomia Sunset Suites Mykonos
A poolside area with lounge chairs and a view of the sea.
A bar area with a view of the sea and a hillside.
A poolside area with two lounge chairs and an umbrella, overlooking a calm sea with boats and a hilly landscape in the background.
A hotel room with a bed, a chair, a nightstand, a lamp, and a view of the sea.

17. Kalesma Mykonos

Kalesma Mykonos
Mykonos
United States
Giovanis
$514 nightly
$603 total
Oct 3 - Oct 4
Total with taxes and fees
Kalesma Mykonos
A modern building with a pool, set against a rocky coastline and the sea.
A modern interior with a water feature, large rocks, and a minimalist design.
A modern building with multiple levels and balconies, surrounded by large rocks.
A bedroom with a bed, a lamp, a door, and a window.

18. Armacaas Mykonos Hotel

Armacaas Mykonos Hotel
Mykonos
United States
Yarleny
$136 nightly
$173 total
Sep 26 - Sep 27
Total with taxes and fees
Armacaas Mykonos Hotel
A modern outdoor lounge area with a pool, wooden pergola, and hanging chairs.
A beach with yellow and white umbrellas, a sandy area, and a view of the sea and distant mountains.
A view through an arched doorway with a Buddha statue, a clear blue sky, and the sea.
A beachside restaurant with wicker furniture, stone pillars, and umbrellas overlooking the sea.

19. Santa Marina, a Luxury Collection Resort, Mykonos

Santa Marina, a Luxury Collection Resort, Mykonos
Mykonos
United Kingdom
FLORENCE
$514 nightly
$603 total
Sep 24 - Sep 25
Total with taxes and fees
Santa Marina, a Luxury Collection Resort, Mykonos
A modern kitchen with a stone accent wall, wooden cabinets, and a view of the sea.
A modern hotel room with a large bed, a sofa, a dining area, and a view of the city.
A spa area with a stone wall, a reception desk, and shelves with spa products.
A modern living room with a dining area, a flat-screen TV mounted on the wall, and a cozy seating area with a sofa and a side table.

20. Tinos Beach Hotel

Tinos Beach Hotel
Tinos
$185 nightly
$228 total
Sep 23 - Sep 24
Total with taxes and fees
Tinos Beach Hotel
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Syros.
Poseidon Hotel & Suites

Poseidon Hotel & Suites

Mykonos Town Mykonos Mykonos Island
$148 nightly
$180 total
Oct 8 - Oct 9
Total with taxes and fees
9.6/10 Exceptional! (1,000 reviews)
Poseidon Hotel & Suites
Petasos Beach Resort & Spa, Small Luxury Hotels of the World

Petasos Beach Resort & Spa, Small Luxury Hotels of the World

Platis Yialos Mykonos Mykonos Island
$238 nightly
$283 total
Oct 6 - Oct 7
Total with taxes and fees
Petasos Beach Resort & Spa, Small Luxury Hotels of the World
Mykonos Bay Resort & Villas

Mykonos Bay Resort & Villas

Megali Ammos Mykonos Mykonos Island
$177 nightly
$213 total
Oct 9 - Oct 10
Total with taxes and fees
Mykonos Bay Resort & Villas
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Syros

Wander through Ermoupoli's neoclassical buildings and marble squares before catching a performance at the historic Apollo Theater. Swim at Galissas beach, then climb the hill to Ano Syros where medieval streets offer spectacular views across the Aegean.

See all hotels in Syros
A cobblestone street lined with colorful buildings, a prominent yellow church with a blue dome, and a clear blue sky.

Top Syros Hotel Reviews

Myconian Korali Relais & Chateaux

Myconian Korali Relais & Chateaux

10/10 Excellent
"Property was very nice, the staff were excellent. Pools were cold. No issues. Would recommend."
Mark 2-night trip
Posted 2 hours ago
Myconian Korali Relais & Chateaux
CAVO TAGOO MYKONOS

CAVO TAGOO MYKONOS

10/10 Excellent
"Beautiful view, I stayed at the pool bar to watch one of the most beautiful sunsets I ve seen in my life. Staff was so helpful, Isabella at the restaurant and Nikkos at the reception were exceptional. I will certainly come back 🤗"
Evita Graciela 1-night trip
Posted 3 hours ago
CAVO TAGOO MYKONOS
Myconian Ambassador Hotel Relais & Chateaux

Myconian Ambassador Hotel Relais & Chateaux

10/10 Excellent
"Great property, friendly staff, only down side is the free breakfast you used to be able to get it in the room now they make you go down to the restaurant which is an inconvenient compared to previous year. Overall great and recommend"
Mina 7-night trip
Posted 5 hours ago
Myconian Ambassador Hotel Relais & Chateaux
Tropicana Suites & Villas

Tropicana Suites & Villas

10/10 Excellent
"This is an amazing hotel. The view is incredible. The best thing is the staff. Thank you Anastasia!"
velina 3-night trip
Posted 23 hours ago
Tropicana Suites & Villas
Myconian Deos - The Set

Myconian Deos - The Set

10/10 Excellent
"The staff was so friendly and accommodating. The rooms were spacious, clean, modern with all the essentials provided. There is a small walk into town but they have go-carts that can take you into town and back. There is a beach club access through their other property with shuttle that takes you there and back. Definitely worth it."
Valeriy 2-night trip
Posted 2 days ago
Myconian Deos - The Set
Saint John Hotel Villas & Spa

Saint John Hotel Villas & Spa

10/10 Excellent
"Overall good hotel! Very friendly staffs! Enjoyed the beach and pool. Wish their hair dryer could be better!"
MENG 3-night trip
Posted 5 days ago
Saint John Hotel Villas & Spa

Find out more about Syros

Ready to experience the next standard in luxury? We know you're thinking about it. Add even more pleasure on your next trip to Syros by treating yourself to the best of the best when it comes to lodging. It's an ideal pairing. There's no reason to delay a getaway to Syros any longer. You'll join the multitudes of vacationers who have made Syros so fashionable in the last few seasons. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. You deserve an outstanding getaway. Book one of Expedia's luxurious 5-star hotels in Syros and get ready to be pampered like never before.

5-Star Hotels in Syros

You'll have a fantastic time at one of these 5-star hotels. High-end restaurants, excellent customer care, and rejuvenating spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also look forward to an outstanding experience and fantastic customer care, so get ready to kick back and indulge. What kind of amenities will make your stay a wonderful one? A mud wrap treatment that will leave you feeling refreshed and alive? 24-hour room service, so you can order that Turkish coffee in the wee hours of the morning? A full-body massage to help your cares fall away?

But you aren't going to spend your entire vacation in your room, of course. We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Syros are waiting for you to relax after an exciting day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs.

Make Your Escape

The results are in, and Syros 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Don't put off your dream vacation any longer -- this is a great time to find 5-star hotel deals in @region! Select one of the 5-star hotels in Syros today and decompress in total tranquility when you're ready.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Syros?
The amount you pay for a 5-star hotel in Syros depends on factors like when you plan to go and the length of your trip. A top tip for bagging an awesome deal? Use our pricing filters to check out the available hotels for your selected dates.
  • Search for the lowest price per night from $180
What makes a hotel 5 stars in Syros?
From gourmet dining venues and all-day gyms to pools and dreamy bedding, the 5-star experience in Syros is all about indulgence and comfort. But it requires more than just upscale perks to get a 5-star rating. Accommodations also have to offer exceptional services like massage treatments, laundry and dry cleaning and a nightly turn-down service.
Are there any 5-star all-inclusive resorts in Syros?
Our handy filters are the easiest way to find exactly what you're looking for. Select "All inclusive" and "5-star" to show the finest resorts in Syros where your meals, lodging, activities and entertainment are included in the price. At these escapes, your vacation is pure leisure from the moment you step foot in the lobby.

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