Find 5 Star Hotels in Winston-Salem, NC from $93

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Check availability on Winston-Salem 5 Star Hotels

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Dec 8 - Dec 9
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Dec 12 - Dec 14
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Winston-Salem.
DoubleTree by Hilton Winston Salem - University

DoubleTree by Hilton Winston Salem - University

5790 University Pkwy Winston-Salem NC
$82 nightly
The price is $93 total per night from Jan 9 to Jan 10
$93 total
Jan 9 - Jan 10, 2026
Total with taxes and fees
8.2/10 Very Good! (1,000 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Winston-Salem

Explore Old Salem's living history museum where costumed interpreters demonstrate crafts and daily life from the 1700s. Discover the city's artistic side at Reynolda House, featuring American art within the historic estate of tobacco magnate R.J. Reynolds.

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Top Winston-Salem Hotel Reviews

Find out more about Winston-Salem

You enjoy the finer things in life, both at home and on vacation. Add an extra layer of pleasure on your next trip to Winston-Salem by treating yourself to the best of the best when it comes to lodging. It's an ideal fusion. There's no reason to delay a getaway to Winston-Salem any longer. You'll join the multitudes of vacationers who have made Winston-Salem so fashionable in the last year. Additionally, the hotels in this area receive outstanding marks for guest services, so you know you'll be well cared for during your getaway. Don't wait any longer. Reserve one of our 5-star hotels in Winston-Salem and indulge in the finer things in life for a while.

Book the Best Winston-Salem 5-Star Hotels

Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Top-notch service, delicious meals, and personalized service are all at your fingertips. You're sure to find exactly the accommodation you need. We should also mention, the hotels in this area receive fantastic marks for guest services, so you know you'll be looked after during your getaway. How do you want to relax? A concierge to help you make reservations at that outstanding restaurant? A deep-tissue massage to help your cares fall away? High thread-count sheets, delectable chocolate desserts, and even space for your family pet in some cases...these hotels are one-of-a-kind.

You won't sleep and order room service the entire time, though. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Winston-Salem are the perfect place to rest up after an exciting day. Ready to learn more? Then explore the 694 reviews various guests have left on Expedia and get to know these places.

Your Getaway Starts Today

The results are in, and Winston-Salem 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. Expedia can help you land a great deal on accommodation. It's time to indulge yourself. Choose one of the 5-star hotels in Winston-Salem today and decompress in total tranquility tomorrow.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Winston-Salem?
The amount you pay for a 5-star hotel in Winston-Salem depends on things like when you want to go and the length of your break. A top tip for landing the best deal? Use our pricing filters to compare the available hotels for your chosen dates.

  • Search for the lowest price per night from $93

What makes a hotel 5 stars in Winston-Salem?
From high-end restaurants and all-day gyms to swimming pools and superior bedding, the 5-star experience in Winston-Salem is all about relaxation and luxury. But it requires more than just top-notch amenities to get a 5-star rating. Stays also have to offer exceptional services like massage treatments, laundry and dry cleaning and 24-hour concierge services.
Are there any 5-star all-inclusive resorts in Winston-Salem?
Use our filters to find a high-end retreat in Winston-Salem where most of what you need is included. After your initial search, refine your results for properties that have 5 stars and are deemed "All inclusive." The main thing on the schedule at these stays? Pure indulgence and relaxation.

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