Search Vacation Homes in 5th and Missouri Station

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Our top choices for 5th and Missouri Station vacation homes

Vacation Home in The Gate

Entire 4BR Home near Lafayette Square
9.8 out of 10, Exceptional, (85)
"What a great stay! We had everything we needed and the owners even went out of their way to accommodate an easier way to get into the house for a family member who had a recent surgery. "
United States
Linda L.
$340 nightly
The price is $352
Dec 27 - Dec 28
Total with taxes and fees
Entire 4BR Home near Lafayette Square
9.8 out of 10, Exceptional, (7)
"This was a really nice place that’s just a few minutes away from every attraction and restaurant we wanted to visit. Plenty of room and beds for a large crowd. We liked that there private off the street parking, too."
United States
Randy M.
Artsy Creative Haven Home St. Louis Art District

Vacation Home in Lafayette Square

Historic luxury retreat
9.8 out of 10, Exceptional, (162)
"Excellent spot for a family trip to St Louis. Great location and very responsive to all needs!!"
United States
Liz S.
Historic luxury retreat
9.4 out of 10, Exceptional, (6)
"Yes, we loved the property and everything was perfect to our likings. "
United States
Markquetta
Modern Downtown Haven: Near STL Zoo, Arch & Park
2.0 star property
9.8 out of 10, Exceptional, (12)
"Very clean, like new, comfy beds"
United States
Scott or Janet T.
Spacious City Retreat w/ 2 Car Garage by StayLage
7.4 out of 10, Good, (3)
"Couldn’t check in on time due to cleaning and then someone partied Next Door All night and Did Donuts in their vehicle for hrs. Until about 4am. Even Noticed police talk to them and go back to party for hrs. lol. Other days were peaceful though. "
United States
Jason H.
$366 nightly
The price is $427
Dec 14 - Dec 15
Total with taxes and fees
3BR St. Louis Home | Games + Free Parking
9.4 out of 10, Exceptional, (50)
"It was very good stay! Thank you! "
United States
Trey S.
Rustic Charm 4BDRM Home| STL Developers
9.8 out of 10, Exceptional, (34)
"Awesome property for our group. "
United States
Justin R.
Modern & Luxurious. 4BR. Sleep 12. Minutes to downtown
9.0 out of 10, Wonderful, (2)
"Older home with nice modern touches. Ample space for larger groups. Fully stocked kitchen is always a plus. Hosts were great at communicating prior and during our visit. Really cool little golf cart community only minutes from downtown area."
United States
Matthew M.
3-bedroom house in charming St. Louis historic district Free shuttle to games
9.6 out of 10, Exceptional, (45)
"Great location. Great communication and support from the owner. Lots of bathrooms and beds! Spacious living room with lots of seating. Large table for meals (lots of chairs). Great place for a family gathering. We had 14 and fit very comfortably."
United States
Tim P.
Beautiful 6BR Fox Park Home // 1st Floor Master Bed and Bath + Private Parking!
2.0 star property
Uptown Elegant Escape | JZ Vacation Rentals
The Gathering Spot Downtown St. Louis by StayLage
3.5 star property
Welcoming Lafayette Square Home - JZ Vacation Rentals

Vacation Home in Benton Park

Historic Benton Park HUGE 2 BR Condo
8.4 out of 10, Very Good, (5)
"Place was exactly as advertised. Its a huge and spacious space. The hubby and I enjoyed our stay!"
United States
Melissa M.
Historic Benton Park HUGE 2 BR Condo

Vacation Home in The Gate

A Cottage in Downtown STL. Sleeps 10
2.0 star property
2.0 out of 10, (1)
"Live mice in upstairs bedroom and in kitchen cabinet. Soiled blankets and sofa. Dishwasher had standing water and smelled horrible as did the entire first floor. Did not feel comfortable using anything in kitchen due to mouse droppings and other sanitary issues. The first night we saw a mouse upstairs and contacted the host, the response was “is it still there?” No empathy, no apologies. It was a poor night of sleep for the entire family as we worried. The next morning, a mouse dropped from a...
United States
Mandi
A Cottage in Downtown STL. Sleeps 10

Vacation Home in Lafayette Square

The Marquis Manor | JZ Vacation Rentals
3.0 star property
The Marquis Manor | JZ Vacation Rentals
9.6 out of 10, Exceptional, (24)
"This house was beautiful and in a very nice spot in St. Louis. Close to everything and the hosts were amazing. Would definitely use again "
United States
Justin B.
$261 nightly
The price is $261
Dec 14 - Dec 15
Total with taxes and fees
Brand New! Soulard Charmer - Pet Friendly.

Vacation Home in Old North Saint Louis

4bed/3bath House in St. Louis
9.2 out of 10, Wonderful, (22)
"Very beautiful and spacious home and yard. Plenty of bedrooms. The whole group enjoyed their stay. If we are ever back in St Louis, would rent it again"
United States
rachel h.
4bed/3bath House in St. Louis

Vacation Home in McKinley Heights

3 King Beds/Charm in Historic STL by StayStlouis
9.6 out of 10, Exceptional, (14)
"Location was great for our stay. Property was very clean and had everything we needed. Our kids loved the foosball table!"
United States
Troy O.
$383 nightly
The price is $417
Jan 4 - Jan 5, 2026
Total with taxes and fees
3 King Beds/Charm in Historic STL by StayStlouis
9.8 out of 10, Exceptional, (30)
"Beautiful neighborhood very clean and the host was super "
United States
alice u.
$374 nightly
The price is $405
Jan 6 - Jan 7, 2026
Total with taxes and fees
King Beds/3Baths Renovated Spacious By StayStLouis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top 5th and Missouri Station Hotel Reviews

Find out more about 5th and Missouri Station

What types of Vacation Homes can I find in 5th and Missouri Station?

At Expedia, you’ll find great 5th and Missouri Station Vacation Homes for your family vacation, business trip, romantic weekend break, and more. If you’re planning a vacation with kids, try using the traveler experience filter to select “Family-friendly” 5th and Missouri Station Vacation Homes. Or, if you’re traveling for work, you can check the “Business-friendly” box to find business-oriented places to stay in 5th and Missouri Station. While you’re making your decision, you can use our map facility to view your shortlisted properties and their distance from 5th and Missouri Station, or nearby places of interest. There are great places to stay for every budget, so if you need cheap Vacation Homes in 5th and Missouri Station, use our simple search function to help you secure a great deal.

How much do Vacation Homes cost in 5th and Missouri Station?

The price per night for 5th and Missouri Station Vacation Homes in 2026 can start from as low as *. The cost of Vacation Homes varies depending on a number of factors: the dates of your stay, the exact location of the accommodation, and whether there are any special events taking place near 5th and Missouri Station, to name just three. When there’s a high demand for rooms in 5th and Missouri Station, this can cause prices to increase, whereas traveling during a quieter time of the year can mean lower prices. Booking through Expedia can help you find some of the best deals for cheap Vacation Homes in 5th and Missouri Station, so you can sleep easy without going over your budget.

How to find the best deals on 5th and Missouri Station Vacation Homes?

Expedia’s search function can help you find some of the best deals on 5th and Missouri Station Vacation Homes. You can select a minimum and maximum price per night according to your budget, and filter by guest ratings and star ratings to ensure you find the right Vacation Homes for your needs. Changing the sort order according to price can also help you to view cheap Vacation Homes in 5th and Missouri Station at a glance, and you can combine this with our own picks to highlight some of the best available offers. Don’t forget, if you’re an Expedia Rewards member, you can use the “Member Prices” filter to make extra savings on your booking.

Why should I choose Expedia to book 5th and Missouri Station Vacation Homes?

Booking with Expedia allows you to browse a wide selection of places to stay in 5th and Missouri Station, complete with search filters that make it easy to locate Vacation Homes that best meet your specific requirements. Our clear and easy-to-use search function makes it effortless to compare amenities, prices, property types, neighborhoods, and much more. At Expedia, you can also find flights, car rental, and activities, and you can combine your bookings for greater savings. Plus, Expedia Rewards members accrue points on all eligible purchases. Build your points total to gain discounts on subsequent bookings in the future. Membership is free, so go ahead and join.

What is the cancellation policy on booking 5th and Missouri Station Vacation Homes?

At Expedia, we understand that plans change, and the good news is you can cancel many bookings for 5th and Missouri Station Vacation Homes with a full refund, depending on the rules and restrictions. For example, some Vacation Homes may not give refunds if you cancel your booking within 24 or 48 hours of your arrival date, and some bookings are non-refundable. Be sure to view the policies provided by the 5th and Missouri Station Vacation Homes, and confirm the exact cancellation window on your selected location’s details page. If free cancellation is important to you, you can filter for the “Fully refundable” payment type when you search for your Vacation Homes.

*Prices and availability are subject to change. Additional terms may apply 

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