Hotels near 5th and Missouri Station

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Nov 14 - Nov 15
Tomorrow
Nov 15 - Nov 16
Next weekend
Nov 20 - Nov 22
In two weeks
Nov 27 - Nov 29

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Popular sort options for 5th and Missouri Station hotels

Our top choices for 5th and Missouri Station hotels

A rooftop terrace with wicker chairs and a glass balustrade overlooking a bridge.

1. Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
1.6 mi from 5th and Missouri Station
9.6 out of 10, Exceptional, (3,837 reviews)
"Very nice hotel.. love that are arch is right behind it.."
United States
Nicole
$135 nightly
The price is $158
Dec 13 - Dec 14
Total with taxes and fees
Drury Plaza Hotel St. Louis at the Arch
A modern outdoor lounge area with seating, a bar, and a view of a cityscape.

2. Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
1.8 mi from 5th and Missouri Station
9.4 out of 10, Exceptional, (1,364 reviews)
"Great place to stay."
United States
brandon
$139 nightly
The price is $165
Nov 15 - Nov 16
Total with taxes and fees
Live by Loews - St.Louis
A modern hotel lobby with a glass facade, seating area, and a staircase.

3. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
1.4 mi from 5th and Missouri Station
9.4 out of 10, Exceptional, (1,000 reviews)
"Exactly what you would expect from a four seasons hotel. Fantastic, all the way around!"
United States
JEFFREY
$375 nightly
The price is $438
Nov 15 - Nov 16
Total with taxes and fees
Four Seasons Hotel St Louis
A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

4. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
1.7 mi from 5th and Missouri Station
9.0 out of 10, Wonderful, (1,368 reviews)
"Loved our stay!"
United States
Megan
$105 nightly
The price is $125
Dec 10 - Dec 11
Total with taxes and fees
Embassy Suites by Hilton St. Louis Downtown
A multi-story building with a classic architectural style, featuring numerous windows and a brick facade.

5. Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center
3.0 star property
1.8 mi from 5th and Missouri Station
9.0 out of 10, Wonderful, (1,000 reviews)
"Good for a quick stay a little pricey for what you get"
United States
Jackson
$97 nightly
The price is $115
Nov 22 - Nov 23
Total with taxes and fees
Courtyard by Marriott St. Louis Downtown/Convention Center
A modern dining area with multiple tables and chairs, large windows with a city view, and contemporary lighting fixtures.

6. Hotel Saint Louis, Autograph Collection

Hotel Saint Louis, Autograph Collection
4.0 star property
1.8 mi from 5th and Missouri Station
9.0 out of 10, Wonderful, (596 reviews)
"Super cool hotel, beautiful, clean, and helpful staff."
United States
Shawn
$159 nightly
The price is $189
Nov 15 - Nov 16
Total with taxes and fees
Hotel Saint Louis, Autograph Collection
A historic building with a corner entrance, a prominent "Penny Well Hotel" sign, and a fire hydrant on the sidewalk.

7. Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
1.6 mi from 5th and Missouri Station
8.8 out of 10, Excellent, (1,161 reviews)
"I enjoyed my stay and parking was safe."
United States
Jacqueline
$110 nightly
The price is $128
Nov 23 - Nov 24
Total with taxes and fees
Hilton Pennywell St. Louis at the Arch
A hotel with a prominent arch structure in the background, a sign for Hampton Inn, and a TGI Friday's restaurant.

8. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
3.5 star property
1.5 mi from 5th and Missouri Station
8.8 out of 10, Excellent, (1,471 reviews)
"Would stay here again with my family"
United States
Andrew
$106 nightly
The price is $124
Nov 22 - Nov 23
Total with taxes and fees
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
A modern hotel room with a large bed, a nightstand, a mirror, and a view of the city through arched windows.

9. The Westin St. Louis

The Westin St. Louis
4.5 star property
1.9 mi from 5th and Missouri Station
8.8 out of 10, Excellent, (1,003 reviews)
"Amazing property, staff was very friendly, great location!!"
United States
Stacy
$122 nightly
The price is $143
Nov 22 - Nov 23
Total with taxes and fees
The Westin St. Louis
A spacious lobby with a polished floor, a large chandelier, and a central table with a potted plant.

10. Missouri Athletic Club

Missouri Athletic Club
3.5 star property
1.5 mi from 5th and Missouri Station
8.8 out of 10, Excellent, (1,003 reviews)
"Great stay."
United States
Heather
$158 nightly
The price is $185
Nov 16 - Nov 17
Total with taxes and fees
Missouri Athletic Club
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to 5th and Missouri Station

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A rooftop terrace with wicker chairs and a glass balustrade overlooking a bridge.
Drury Plaza Hotel St. Louis at the Arch
3.0 star property
9.6
Exceptional
3,837 reviews
View
A modern outdoor lounge area with seating, a bar, and a view of a cityscape.
Live by Loews - St.Louis
4.0 star property
9.4
Exceptional
1,364 reviews
View
A modern hotel lobby with a glass facade, seating area, and a staircase.
Four Seasons Hotel St Louis
5.0 star property
9.4
Exceptional
1,000 reviews
View
A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.
Embassy Suites by Hilton St. Louis Downtown
4.0 star property
9.0
Wonderful
1,368 reviews
View
A multi-story building with a classic architectural style, featuring numerous windows and a brick facade.
Courtyard by Marriott St. Louis Downtown/Convention Center
3.0 star property
9.0
Wonderful
1,000 reviews
View

Top 5th and Missouri Station Hotel Reviews

A room with a dark wooden door, a chandelier, green plants, and a seating area with a sofa and chairs.
Truitt Hotel

Truitt Hotel

Truitt Hotel
Lafayette Square

10/10 Excellent

It was a nice getaway feel
United States
Whitney
Reviewed November 10, 2026
Truitt Hotel

Frequently Asked Questions

What's the area like around 5th and Missouri Station?

5th and Missouri Station is located in a welcoming area of East St. Louis known for its array of dining options and sporting events. You'll find 733 hotels and other accommodations within a few miles for a convenient home base.

Where is the best place to stay close to 5th and Missouri Station?

Hyatt Regency St. Louis at The Arch is one of the top choices for your stay based on our traveler data, and this hotel offers 3 restaurants and 2 bars. It's located 1.5 mi (2.5 km) from 5th and Missouri Station. Other good choices within a few miles include Drury Plaza Hotel St. Louis Union Station and Drury Plaza Hotel St. Louis at the Arch.

How many hotels will I find close to 5th and Missouri Station?

Expedia has 733 hotels and other accommodations a few miles from 5th and Missouri Station.

What can I see and do near 5th and Missouri Station?

You might want to spend some time browsing the exhibits at City Museum, Museum at the Gateway Arch, or National Blues Museum. St. Louis Union Station, Washington Avenue Historic District, and Anheuser-Busch Brewery are landmarks that you won't want to miss. You can watch performances at Powell Hall, Powell Symphony Hall, and St. Louis Symphony Orchestra if you're interested in local theater.

Explore a world of travel with Expedia