Applegate Vacations from $604

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Your Applegate Vacation

When you book a Applegate vacation package, it's all about letting go and enjoying your escape to the fullest. Uncover the highlights of this vibrant city knowing that all your travel needs have been looked after before you go. Make your trip to Applegate even more fun by including some sightseeing. Red Lily Vineyards, Enchanted Forest Trail and Applegate Library are some of the most popular attractions you'll want to explore. Expedia will help you escape the everyday. Tailor your vacation to Applegate to suit your travel style, whatever that may look like.

The Latest Applegate vacation packages

Price found within the past 48 hours. Click for updated prices.
My Place Hotel-Medford OR

My Place Hotel-Medford OR

3 out of 5
Price was $714, price is now $604 per person
$604
per person
Nov 9 - Nov 14
found 1 day ago
Roundtrip flight included
Minneapolis (MSP) to Medford (MFR)
9.2/10 Wonderful! (1,452 reviews)
We had a quick stop as we passed through Medford and it was exactly what we needed.

Reviewed on Sep 26, 2025

Courtyard by Marriott Medford Airport

Courtyard by Marriott Medford Airport

3 out of 5
Price was $868, price is now $718 per person
$718
per person
Nov 9 - Nov 14
found 1 day ago
Roundtrip flight included
Minneapolis (MSP) to Medford (MFR)
9/10 Wonderful! (821 reviews)
Such a great stay close to the airport. Large lobby, with food and cocktails. Good outdoor patio for those nice evenings. Rooms are large and comfortable for lounging. Easy access to the airport for early flights or late arrivals.

Reviewed on Sep 22, 2025

Don't see what you're looking for?
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Discover the most popular places to visit in Applegate

One of about a dozen wineries located here along the Applegate Wine Trail.

Red Lily Vineyards

You can enjoy a tasting or tour at Red Lily Vineyards during your travels to Jacksonville. Discover the coffeehouses and festivals in this relaxing area.

Red Lily Vineyards

Britt Pavilion

Get tickets for a show at Britt Pavilion, a storied theater in Jacksonville. While you're here, you can savor the top-notch restaurants.

Britt Pavilion

Applegate Lake

Commune with nature and explore the great outdoors at Applegate Lake during your travels in Jacksonville. Discover the restaurants and live music in this walkable area.

Applegate Lake

What to do in Applegate

Salem Puzzling Adventure

Ashland Puzzling Adventure

$35
per traveler
Ashland Puzzling Adventure
See all activities in Applegate

Applegate Hotel Deals

Rogue Regency Inn and Suites

Rogue Regency Inn and Suites

3 out of 5
2300 Biddle Rd, Medford, OR
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $122 total per night from Sep 27 to Sep 28
$122 total
Sep 27 - Sep 28
Total with taxes and fees
8.8/10 Excellent! (2,447 reviews)
"Close to places we needed to go."

Reviewed on Sep 26, 2025

Rogue Regency Inn and Suites
Riverside Inn

Riverside Inn

2.5 out of 5
986 S.W. 6th, Grants Pass, OR
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $136 total per night from Oct 5 to Oct 6
$136 total
Oct 5 - Oct 6
Total with taxes and fees
9.4/10 Exceptional! (1,786 reviews)
"NICE PLACE TO REST, HAVE A GLASS OF WINE ON THE BALCONY AND CHECK OUT THE RIVER — THANKS!"

Reviewed on Sep 25, 2025

Riverside Inn
Quality Inn & Suites Medford Airport

Quality Inn & Suites Medford Airport

2.5 out of 5
1950 Biddle Rd, Medford, OR
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $94 total per night from Oct 26 to Oct 27
$94 total
Oct 26 - Oct 27
Total with taxes and fees
8.4/10 Very Good! (1,015 reviews)
Pleasant overnight accommodations
"Clean and comfortable size room to relax in. Quiet and within walking distance to dining."

Reviewed on Sep 24, 2025

Quality Inn & Suites Medford Airport
See all 534 properties in Applegate
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does an Applegate vacation package cost?
You'll find cheap prices from $604 on Expedia for your Applegate escape. However, a range of factors like your choice of hotel, the season and length of stay will influence how much your vacation to Applegate costs.
What are the cheapest months to go to Applegate?
January, October and December are great times to search for cheap Applegate vacation packages. Opting to travel in less busy periods means you can usually find lower prices on flights and accommodations.
How many days is enough for Applegate?
The ideal duration for your Applegate vacation depends on what you'd like to do and see. Generally, a handful of days to a week will give you plenty of time to check out all the top attractions and discover some hidden gems along the way.
How to find the best Applegate package deals?
Use Expedia's handy filters to find some of the best Applegate package deals. When you start your search, just set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your adventure for midweek, or browse for Applegate package deals in the off-season. Play around with your travel dates and you may land even better discounts. As a rule of thumb, it's typically best to lock in your vacation package as early as possible.
Is it cheaper to book an Applegate vacation as a package?
You can enjoy significant savings on your Applegate retreat by booking a personalized vacation package. Click on the "Package" heading, then select your travel dates and destination to see the best hotel and flight prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may land a better deal.
When to book a vacation package to Applegate?
If you have your Applegate vacation dates locked in, book early to bag some incredible deals. With Expedia, you can typically reserve some flights up to a year in advance. Prefer spontaneous adventures? Our last-minute deals are great for impromptu escapes.
Does Expedia offer Book Now, Pay Later Applegate vacation packages?
If you're anything like us, you love exploring new places but don't love the big price tag that can sometimes come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the overall cost of your Applegate trip over 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can snap up great vacation packages with payment plans as soon as you spot them.

Explore a world of travel with Expedia

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.