Byron Vacations from $364

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Your Byron Vacation

Book a tailored Byron vacation package that includes only the things you need and nothing you don't. Good for bars and pubs, history and culture, think about staying in the neighborhood of Downtown Rochester. There's plenty to put on your must-do list during your trip to Byron, starting with leading attractions such as Oxbow Park and Douglas Trail. A couple of quick clicks is all it takes to put together the ultimate Byron vacation on Expedia.

The Latest Byron vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
Downtown Rochester
Price was $523, price is now $364 per person
$364
per person
Feb 6 - Feb 10
found 1 day ago
Roundtrip non-stop flight included
Jacksonville (JAX) to Rochester (RST)
17.6/10 Exceptional! (867 reviews)
room clean poor location

Reviewed on Nov 24, 2025

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
Downtown Rochester
Price was $628, price is now $479 per person
$479
per person
Feb 6 - Feb 10
found 1 day ago
Roundtrip non-stop flight included
Jacksonville (JAX) to Rochester (RST)
16.4/10 Exceptional! (1,746 reviews)
Close and convenient for MAYO clinic patient's

Reviewed on Nov 22, 2025

Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
Downtown Rochester
Price was $601, price is now $463 per person
$463
per person
Feb 6 - Feb 10
found 1 day ago
Roundtrip non-stop flight included
Jacksonville (JAX) to Rochester (RST)
16/10 Exceptional! (1,495 reviews)
Clean room and friendly staff

Reviewed on Nov 22, 2025

Country Inn & Suites Rochester South Mayo Clinic

Country Inn & Suites Rochester South Mayo Clinic

3 out of 5
Price was $534, price is now $418 per person
$418
per person
Feb 6 - Feb 10
found 1 day ago
Roundtrip non-stop flight included
Jacksonville (JAX) to Rochester (RST)
16.8/10 Exceptional! (1,001 reviews)
Clean room, fun staff.

Reviewed on Nov 18, 2025

Aspen Select

Aspen Select

3.5 out of 5
Price was $560, price is now $439 per person
$439
per person
Feb 6 - Feb 10
found 1 day ago
Roundtrip non-stop flight included
Jacksonville (JAX) to Rochester (RST)
16.8/10 Exceptional! (1,003 reviews)
Great room ,staff some of the best we have meet

Reviewed on Nov 23, 2025

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Discover the most popular places to visit in Byron

Oxbow Park

Explore the great outdoors at Oxbow Park, a lovely green space in Byron. Check out the top-notch restaurants or charming coffeehouses in this walkable area.

Oxbow Park

Byron Hotel Deals

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $128 total per night from Nov 25 to Nov 26
$128 total
Nov 25 - Nov 26
Total with taxes and fees
8.2/10 Very Good! (1,762 reviews)
Yes

Reviewed on Nov 20, 2025

Kahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $125 total per night from Nov 25 to Nov 26
$125 total
Nov 25 - Nov 26
Total with taxes and fees
7.8/10 Good! (1,504 reviews)
Safe and convenient to Mayo clinic

Reviewed on Nov 21, 2025

Kahler Inn and Suites - Mayo Clinic Area
Spark by Hilton Rochester South

Spark by Hilton Rochester South

3 out of 5
4165 Maine Ave SE Rochester MN
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $79 total per night from Dec 7 to Dec 8
$79 total
Dec 7 - Dec 8
Total with taxes and fees
9.2/10 Wonderful! (278 reviews)
I felt I am at home. Everything i wanted was there.

Reviewed on Nov 20, 2025

Spark by Hilton Rochester South
See all 381 properties in Byron
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Byron Vacation Packages

Byron Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Rochester Intl. Airport (RST)
Population
5,300
Top Sights
Rochester Civic Theater, Minnesota Childrens Museum and Cascade Lake Beach

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Frequently asked questions

How much does a Byron vacation package cost?
Offering great value package deals from $364 on Expedia, you'll be thrilled with how little a vacation to Byron costs! Expedia's packages make travel planning easier and save you more.
What are the cheapest months to go to Byron?
December, January and February are the best times to look for cheap Byron vacation packages. Choosing to travel in less busy months means you'll typically find lower prices on accommodations and flights.
How many days is enough for Byron?
Generally, a handful of days is enough to tick off the main sights during your Byron vacation. However, if you'd like to have more time to unwind or take day trips, consider extending your trip.
How to find the best Byron package deals?
Landing a cheap Byron package deal is a breeze with Expedia. Once you've entered your destination and trip dates under our "Packages" tab, set your budget range, add some filters and see what's available. You can tailor your search by "Amenities," "Property type," "Traveler experience" and more. Sort the results by "Price: low to high" to discover the most pocket-friendly Byron package deals. Want a simple trick to score even more savings? Be flexible with your departure dates and consider going away on a weekday, when prices are often lower.
Is it cheaper to book a Byron vacation as a package?
You can enjoy significant savings on your Byron break by booking a personalized vacation package. Click on the "Package" heading, then enter your destination and travel dates to view the best hotel and flight prices. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a car rental and you may land a better deal.
When to book a vacation package to Byron?
If you have your Byron travel dates finalized, book as soon as you can to bag some incredible deals. With Expedia, you can generally reserve some flights up to a year in advance. Prefer spontaneous trips? Our last-minute deals are perfect for setting off on a whim.
Does Expedia offer Book Now, Pay Later Byron vacation packages?
If you're anything like us, you love traveling but don't love the price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the overall cost of your Byron vacation over 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can secure cheap vacation packages with payment plans as soon as you spot them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.