Title: $58 Car Rental Medical Center, MI - Expedia.com [Medical Center Travel Guide](https://expedia.com/Detroit-Medical-Center.dx802472874695356416)[Hotels in Medical Center](https://expedia.com/Medical-Center-Detroit-Hotels.0-n802472874695356416-0.Travel-Guide-Filter-Hotels)[Flights to Detroit](https://expedia.com/Cheap-Flights-To-Detroit.d178255.Travel-Guide-Flights)[Things to do in Detroit](https://expedia.com/Things-To-Do-In-Detroit.d178255.Travel-Guide-Activities)[Medical Center Vacations](https://expedia.com/Medical-Center.d802472874695356416.Destination-Travel-Guides) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_car.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # $58 Car Rental Medical Center, MI ## Search and Compare from Car Companies in Medical Center ## Featured car rental suppliers Compare from agencies ![car suppliers logo](https://forever.travel-assets.com/flex/flexmanager/images/2022/02/16/car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car rentals - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car rentals [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Top Car Deals in Medical Center \* Price found within the past 6 days. Click for updated prices. Mon, Feb 16 - Tue, Feb 17 ### Standard Van Toyota Sienna or similar - 8 people - Unlimited mileage ![Dollar](//mediaim.expedia.com/cars/logos/ZR.png) Detroit, Michigan, USA ![Toyota Sienna](//mediaim.expedia.com/cars/43/4cdcf7f5-bed8-4be8-bdde-97bb9b53f699.jpg) #### $58 includes taxes & fees $42 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.212510&olon=-83.353330&date1=2/16/2026&date2=2/17/2026&pprfrr=41.99&tprfrr=58.43&cvrfrr=ZR&ctrfrr=SV&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22van%22]) Mon, Feb 16 - Tue, Feb 17 ### Mini Van Chrysler Pacifica or similar - 7 people - Unlimited mileage ![Dollar](//mediaim.expedia.com/cars/logos/ZR.png) Detroit, Michigan, USA ![Chrysler Pacifica](//mediaim.expedia.com/cars/43/9c129e79-2a68-4e58-97b3-110d1119e59c.jpg) #### $61 includes taxes & fees $44 per day found 9 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.212510&olon=-83.353330&date1=2/16/2026&date2=2/17/2026&pprfrr=44.24&tprfrr=61.13&cvrfrr=ZR&ctrfrr=MV&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22minivan%22]) Mon, Feb 16 - Tue, Feb 17 ### Compact SUV Chevrolet Trax or similar - 5 people - Unlimited mileage ![Thrifty](//mediaim.expedia.com/cars/logos/ZT.png) Detroit, Michigan, USA ![Chevrolet Trax](//mediaim.expedia.com/cars/45/e5049869-5354-4b79-b9ed-1c3a5a8f0f87.jpg) #### $87 includes taxes & fees $66 per day found 9 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.237070&olon=-83.355780&date1=2/16/2026&date2=2/17/2026&pprfrr=65.99&tprfrr=87.24&cvrfrr=ZT&ctrfrr=CF&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22suv%22]) Mon, Feb 16 - Tue, Feb 17 ### Economy Chevrolet Spark or similar - 4 people - Unlimited mileage ![Dollar](//mediaim.expedia.com/cars/logos/ZR.png) Detroit, Michigan, USA ![Chevrolet Spark](//mediaim.expedia.com/cars/43/b709c353-edf9-46a5-98da-f1197c7af6eb.jpg) #### $89 includes taxes & fees $68 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.212510&olon=-83.353330&date1=2/16/2026&date2=2/17/2026&pprfrr=67.69&tprfrr=89.26&cvrfrr=ZR&ctrfrr=EC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22economy%22]) Mon, Feb 16 - Tue, Feb 17 ### Special Wild Card Compact or larger if available or similar - 5 people - Unlimited mileage ![Thrifty](//mediaim.expedia.com/cars/logos/ZT.png) Detroit, Michigan, USA ![Wild Card Compact or larger if available](//mediaim.expedia.com/cars/45/c51b48dd-8870-4d51-8c96-7f12f1215074.jpg) #### $90 includes taxes & fees $68 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.237070&olon=-83.355780&date1=2/16/2026&date2=2/17/2026&pprfrr=67.96&tprfrr=89.59&cvrfrr=ZT&ctrfrr=XX&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22other%22]) Mon, Feb 16 - Tue, Feb 17 ### Midsize SUV Nissan Rogue or similar - 5 people - Unlimited mileage ![Dollar](//mediaim.expedia.com/cars/logos/ZR.png) Detroit, Michigan, USA ![Nissan Rogue](//mediaim.expedia.com/cars/43/b6e9269d-6a75-4e13-9def-306857fa7ff3.jpg) #### $92 includes taxes & fees $70 per day found 9 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.212510&olon=-83.353330&date1=2/16/2026&date2=2/17/2026&pprfrr=69.65&tprfrr=91.62&cvrfrr=ZR&ctrfrr=IF&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22suv%22]) Mon, Feb 16 - Tue, Feb 17 ### Compact Elite Crossover Mercedes-Benz GLA 250 AMG or similar - 5 people - Unlimited mileage ![Thrifty](//mediaim.expedia.com/cars/logos/ZT.png) Detroit, Michigan, USA ![Mercedes-Benz GLA 250 AMG](//mediaim.expedia.com/cars/45/fca0be42-4a8b-490e-986a-349ff271ffc2.jpg) #### $96 includes taxes & fees $73 per day found 12 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.237070&olon=-83.355780&date1=2/16/2026&date2=2/17/2026&pprfrr=72.99&tprfrr=95.62&cvrfrr=ZT&ctrfrr=DG&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22suv%22]) Mon, Feb 16 - Tue, Feb 17 ### Premium Pickup Regular Cab Ford F150 or similar - 5 people - Unlimited mileage ![Alamo](//mediaim.expedia.com/cars/logos/AL.png) Detroit, Michigan, USA ![Ford F150](//mediaim.expedia.com/cars/6/540fb0f7-9b8f-4fbc-93be-7057b591d5a3.jpg) #### $97 includes taxes & fees $75 per day found 9 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.235800&olon=-83.330800&date1=2/16/2026&date2=2/17/2026&pprfrr=74.77&tprfrr=97.38&cvrfrr=AL&ctrfrr=PP&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22pickup%22]) Mon, Feb 16 - Tue, Feb 17 ### Fullsize Chevrolet Malibu or similar - 5 people - Unlimited mileage ![Thrifty](//mediaim.expedia.com/cars/logos/ZT.png) Detroit, Michigan, USA ![Chevrolet Malibu](//mediaim.expedia.com/cars/45/5589fccc-a42b-4acc-8092-e77ea23a122e.jpg) #### $98 includes taxes & fees $75 per day found 9 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.237070&olon=-83.355780&date1=2/16/2026&date2=2/17/2026&pprfrr=74.59&tprfrr=97.55&cvrfrr=ZT&ctrfrr=FC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22fullsize%22]) Mon, Feb 16 - Tue, Feb 17 ### Standard Elite Crossover Volvo XC90 Hybrid - PRESTIGE or similar - 7 people - Unlimited mileage ![Hertz](//mediaim.expedia.com/cars/logos/ZE.png) Detroit, Michigan, USA ![Volvo XC90 Hybrid - PRESTIGE](//mediaim.expedia.com/cars/40/f3df9ee1-4db5-4a63-bdd4-308d5d4ce65a.jpg) #### $102 includes taxes & fees $79 per day found 9 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.211940&olon=-83.348600&date1=2/16/2026&date2=2/17/2026&pprfrr=78.67&tprfrr=102.43&cvrfrr=ZE&ctrfrr=RG&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22suv%22]) Mon, Feb 16 - Tue, Feb 17 ### Luxury Audi A4 or BMW 3 Series or similar - 5 people - Unlimited mileage ![Alamo](//mediaim.expedia.com/cars/logos/AL.png) Detroit, Michigan, USA ![Audi A4 or BMW 3 Series](//mediaim.expedia.com/cars/6/f84d223e-53e9-443e-bfd1-5b43e349e9be.jpg) #### $111 includes taxes & fees $86 per day found 9 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.235800&olon=-83.330800&date1=2/16/2026&date2=2/17/2026&pprfrr=85.99&tprfrr=110.85&cvrfrr=AL&ctrfrr=LC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22luxury%22]) Mon, Feb 16 - Tue, Feb 17 ### Luxury Elite Genesis G80E or similar - 5 people - Unlimited mileage ![Payless](//mediaim.expedia.com/cars/logos/ZA.png) Detroit, Michigan, USA ![Genesis G80E](//mediaim.expedia.com/cars/38/8f159325-6b72-41d1-b84d-a32c367421b1.jpg) #### $112 includes taxes & fees $86 per day found 9 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.212510&olon=-83.353330&date1=2/16/2026&date2=2/17/2026&pprfrr=85.99&tprfrr=112.41&cvrfrr=ZA&ctrfrr=WC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22luxury%22]) Mon, Feb 16 - Tue, Feb 17 ### Midsize Elite Tesla Short Range Model 3 or similar - 5 people - Unlimited mileage ![Payless](//mediaim.expedia.com/cars/logos/ZA.png) Detroit, Michigan, USA ![Tesla Short Range Model 3](//mediaim.expedia.com/cars/38/43c97691-4924-416a-aee6-e348e3ab7c6a.jpg) #### $116 includes taxes & fees $89 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.212510&olon=-83.353330&date1=2/16/2026&date2=2/17/2026&pprfrr=88.99&tprfrr=116.02&cvrfrr=ZA&ctrfrr=JC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22midsize%22]) Mon, Feb 16 - Tue, Feb 17 ### Fullsize Elite Special Audi A5 Sportback or similar - 5 people - Unlimited mileage ![Alamo](//mediaim.expedia.com/cars/logos/AL.png) Detroit, Michigan, USA ![Audi A5 Sportback](//mediaim.expedia.com/cars/6/9badc792-f208-4953-8c60-b76dc5a78943.jpg) #### $114 includes taxes & fees $89 per day found 9 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.235800&olon=-83.330800&date1=2/16/2026&date2=2/17/2026&pprfrr=88.57&tprfrr=113.96&cvrfrr=AL&ctrfrr=GX&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22fullsize%22]) Mon, Feb 16 - Tue, Feb 17 ### Premium Elite SUV Audi Q5 or similar - 5 people - Unlimited mileage ![Enterprise](//mediaim.expedia.com/cars/logos/ET.png) Detroit, Michigan, USA ![Audi Q5](//mediaim.expedia.com/cars/15/92ab4553-9c7b-416a-a168-45e812282eab.jpg) #### $118 includes taxes & fees $92 per day found 8 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.235370&olon=-83.336290&date1=2/16/2026&date2=2/17/2026&pprfrr=92.01&tprfrr=118.08&cvrfrr=ET&ctrfrr=UF&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22suv%22]) Mon, Feb 16 - Tue, Feb 17 ### Oversize SUV Lincoln Navigator L Jeep Grand Wagoneer L or similar - 7 people - Unlimited mileage ![Alamo](//mediaim.expedia.com/cars/logos/AL.png) Detroit, Michigan, USA ![Lincoln Navigator L Jeep Grand Wagoneer L](//mediaim.expedia.com/cars/6/20d6fa90-7442-4047-b6f2-d2db3070d018.jpg) #### $129 includes taxes & fees $101 per day found 9 hours ago [](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.235800&olon=-83.330800&date1=2/16/2026&date2=2/17/2026&pprfrr=100.99&tprfrr=128.87&cvrfrr=AL&ctrfrr=OF&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22suv%22]) ### Don't see what you're looking for? See all car rentals in Medical Center [View all cars](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Medical%20Center,%20Detroit,%20Michigan,%20United%20States%20of%20America&dpln=802472874695356416&date1=2/21/2026&date2=2/23/2026&crfrr=defaultFlex&SearchType=Place) Lowest prices found within the past 8 hours. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=CTG_SPRING_PROMO_802472874695356416) ## Frequently asked questions ### How much is a rental car per day in Medical Center? ### What happens if I need to cancel my Medical Center car reservation? ### Where can I go on a road trip from Medical Center? > - You'll find Michigan State Capitol and many other amazing sights in Lansing. From Medical Center, it's 80 miles away. > - Situated 120 miles away, Akron is also a hit with travelers. Allow time to check out Stan Hywet Hall and Gardens while you're in town. It's one of the reasons people love visiting this vibrant city. > - American Falls is situated 210 miles from Medical Center and is one of the region's most scenic nature spots. Go for a wander around and enjoy the fresh air. ### How do I find the best car rental deals in Medical Center with Expedia? ### How old do you have to be to rent a car in Medical Center? ### What do you need to rent a car in Medical Center? ### What is the cheapest car rental in Medical Center? ### Can I rent a car for a month or longer in Medical Center? ### Where can I find a Medical Center car rental if I am younger than 25? ### What insurance should I choose for my car rental in Medical Center? ## Car Rental Information | Popular car types | [SUV](https://www.expedia.com/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.com/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.com/lp/b/car-rental/economy?rfrr=car.table.Economy) | | ------------------------------------------------ | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available | | | Our best deal of the day | $58 | | Our second best deal of the day | $61 | | Our third best deal of the day | $87 | | From the airport to your hotel | [Airport Transportation](https://www.expedia.com/ground-transfers?rfrr=car.table.AirportTransportation) | | From popular domestic and international airports | [Airport Car Rentals](https://www.expedia.com/lp/b/car-rental/airport) |