1. Downstream Casino Resort

- Location: Quapaw
- Guest rating: 9.4/10 (Exceptional, 154 reviews)
- Price: $109 nightly, $116 total, Nov 15 - Nov 16, Total with taxes and fees, for Our top choices for Carthage hotels with a spa
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Check prices for these dates, December 13 – 14, 2026

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Pool
Breakfast included
Hot tub
4 stars
5 stars
Carthage, Missouri, may be a small town, but it offers a delightful mix of relaxation and exploration perfect for travelers seeking spa hotels. Begin your journey at the stunning Carthage Civil War Museum, where you can immerse yourself in local history while enjoying the serene ambiance of the surrounding grounds. Afterward, take a leisurely stroll through the charming downtown area, known for its beautifully preserved historical architecture, artisanal shops, and quaint cafes, making it a perfect spot for a leisurely afternoon. If you're into outdoor activities, visit the nearby Route 66 Park, where you can unwind with a picnic or a peaceful walk along the scenic trails. For a dash of culture, head to the local art galleries, where you can appreciate the works of regional artists and perhaps find a unique piece to take home. After a day of exploration, retreat to one of the cozy hotels that feature spa services, where you can indulge in rejuvenating treatments designed to pamper you, all while enjoying the warmth of local hospitality. Staying in the heart of Carthage allows you to easily access these points of interest, ensuring your family enjoys both relaxation and adventure with the convenience and quality service you're looking for.
Enjoy staying in a spa hotel in Carthage, with plenty of hotels from $116 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, and may vary depending on the location, season, and hotel amenities. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a trip during the weekend or around public holidays.
Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it’s wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect travel package.
In Carthage, unique spa experiences are available at The Palms Massage & Day Spa and The Pavilion Medical Spa.
The Palms Massage & Day Spa offers a tranquil environment right on the Carthage Square. It specializes in personalized massage, spa, and Ayurvedic treatments, with licensed therapists providing customized sessions including integrative massage and holistic health therapies.
The Pavilion Medical Spa provides nurturing, customized treatments, with a focus on helping clients look and feel their best.
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use Expedia's "Fully refundable property" filter during your search to find the right spa hotel in Carthage for you.