A city square with a fountain, modern buildings, and a historic tower.

Resorts & Hotels with Spas in Missouri from $107

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Top Cities in Missouri

A cityscape with a prominent historic building featuring arched entrances and a large central dome, surrounded by modern skyscrapers and a well-maintained park with a fountain.
HotelsHotels

Kansas City

Kansas City

Check availability on Missouri Resorts & Hotels with Spas

This weekend
Jul 10 - Jul 12
Next weekend
Jul 17 - Jul 19

Our top choices for Missouri hotels with a spa

Couples treatment rooms, hot tub, body treatments, hydrotherapy

The Elms Hotel & Spa, a Destination by Hyatt Hotel

The Elms Hotel & Spa, a Destination by Hyatt Hotel
4.0 star property
Excelsior Springs
8.8 out of 10, Excellent, (1,007 reviews)
  • cleanliness
    Immerse in a rejuvenating spa retreat with 17 treatment rooms, hot tubs, and beautiful garden views at this historic hotel.
$181 nightly
The price is $198
Aug 5 - Aug 6
Total with taxes and fees
The Elms Hotel & Spa, a Destination by Hyatt Hotel
Couples treatment rooms, body treatments, hydrotherapy, aromatherapy

Camden on the Lake Resort & Spa

Camden on the Lake Resort & Spa
4.0 star property
Lake Ozark
9.0 out of 10, Wonderful, (1,004 reviews)
  • cleanliness
    Relax at this lakeside resort with four treatment rooms at Spa 54, featuring hot stone massages, hydrotherapy, and couples' services.
$176 nightly
The price is $189
Jul 12 - Jul 13
Total with taxes and fees
Camden on the Lake Resort & Spa
Couples treatment rooms, hot tub, body treatments, aromatherapy

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,002 reviews)
  • cleanliness
    Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
$375 nightly
The price is $438
Jul 15 - Jul 16
Total with taxes and fees
Four Seasons Hotel St Louis
Snack bar

Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks
3.0 star property
Osage Beach
8.4 out of 10, Very Good, (1,009 reviews)
  • cleanliness
    Lakeside spa resort with golf course offers rejuvenating massages, body treatments, and poolside relaxation.
$224 nightly
The price is $239
Jul 14 - Jul 15
Total with taxes and fees
Margaritaville Lake Resort Lake of the Ozarks
Outdoor spa tub

Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
St. Charles
8.8 out of 10, Excellent, (1,006 reviews)
$155 nightly
The price is $178
Aug 6 - Aug 7
Total with taxes and fees
Embassy Suites by Hilton St. Louis St. Charles
Property amenity

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis
9.6 out of 10, Exceptional, (3,553 reviews)
$153 nightly
The price is $179
Jul 12 - Jul 13
Total with taxes and fees
Drury Plaza Hotel St. Louis at the Arch
Lobby

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4,188 reviews)
$149 nightly
The price is $175
Jul 17 - Jul 18
Total with taxes and fees
Hyatt Regency St. Louis at The Arch
Outdoor dining

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
3.0 star property
Clayton
8.8 out of 10, Excellent, (1,004 reviews)
$130 nightly
The price is $154
Jul 12 - Jul 13
Total with taxes and fees
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Lobby

Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold
3.0 star property
Arnold
9.6 out of 10, Exceptional, (1,002 reviews)
$126 nightly
The price is $146
Jul 26 - Jul 27
Total with taxes and fees
Drury Inn & Suites St. Louis Arnold
Lobby sitting area

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
Riverport
7.6 out of 10, Good, (1,008 reviews)
$93 nightly
The price is $107
Aug 5 - Aug 6
Total with taxes and fees
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Missouri Hotel Reviews

Hotel Lotus Kansas City Stadium

Hotel Lotus Kansas City Stadium

8/10 Good
"The bathtub had mold growing between the tile grout lines."
Alberto 1-night trip
Posted 6 hours ago
Hotel Lotus Kansas City Stadium

Explore a world of travel with Expedia