Resorts & Hotels with Spas in Missouri from $83
Check availability on Missouri Resorts & Hotels with Spas
Pick from 864 Missouri Resorts & Hotels with Spas with updated room rates, reviews, and availability. Most hotels are fully refundable.
The Elms Hotel & Spa, a Destination by Hyatt Hotel
The Elms Hotel & Spa, a Destination by Hyatt Hotel
8.6 out of 10, Excellent, (1010)
"room was clean and spa was wonderful. The restaurant was amazing"
SHELLEY
$153 nightly
The price is $168
Nov 17 - Nov 18
Total with taxes and fees
Camden on the Lake Resort & Spa
Camden on the Lake Resort & Spa
9.0 out of 10, Wonderful, (1008)
"Super convenient to the boat rental and fuel dock. "
Timothy
$146 nightly
The price is $156
Nov 13 - Nov 14
Total with taxes and fees
Four Seasons Hotel St Louis
Four Seasons Hotel St Louis
9.4 out of 10, Exceptional, (1005)
"Beautiful stay at the four seasons! "
Maria
$425 nightly
The price is $497
Oct 25 - Oct 26
Total with taxes and fees
Margaritaville Lake Resort Lake of the Ozarks
Margaritaville Lake Resort Lake of the Ozarks
8.4 out of 10, Very Good, (1019)
"Excellent property, great staff clean and spacious rooms at a great location. "
Martin
$144 nightly
The price is $154
Nov 18 - Nov 19
Total with taxes and fees
Embassy Suites by Hilton St. Louis St. Charles
Embassy Suites by Hilton St. Louis St. Charles
8.8 out of 10, Excellent, (1055)
"The breakfast was very good and the hotel overall very clean and nice!"
Ethan
$139 nightly
The price is $159
Nov 2 - Nov 3
Total with taxes and fees
Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch
9.4 out of 10, Exceptional, (3175)
"Clean rooms, staff was great, love the location!"
Jodi
$144 nightly
The price is $168
Oct 26 - Oct 27
Total with taxes and fees
Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
8.6 out of 10, Excellent, (4024)
"Wonderful stay."
Sheree
$122 nightly
The price is $144
Nov 2 - Nov 3
Total with taxes and fees
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
9.0 out of 10, Wonderful, (887)
"Overall great experience, in a beautiful part of town. Very accessible to a lot of areas including dinning and shopping. Staff was very courteous and helpful!"
Mario R
$118 nightly
The price is $139
Nov 2 - Nov 3
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Missouri Hotel Reviews
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
10/10 Excellent
Explore a world of travel with Expedia
- Jefferson City Hotels
- Cheap Hotels in Jefferson City
- Pet-friendly Hotels in Jefferson City
- Luxury Hotels in Jefferson City
- Hotels with an Indoor Pool in Jefferson City
- Hotels with an Outdoor Pool in Jefferson City
- Resorts & Hotels with Spas in Jefferson City
- Hotels with Hot Tubs in Jefferson City
- Hotels with Bars in Jefferson City
- Historic Hotels in Jefferson City
- Hotels with Restaurants in Jefferson City
- Extended Stay Hotels in Jefferson City
- Hotels with Connecting Rooms in Jefferson City
- Hotels with smoking rooms in Jefferson City
- Hotels with Free Breakfast in Jefferson City
- Hotel Wedding Venues Hotels in Jefferson City
- Family Hotels in Jefferson City
- Hotels with Suites in Jefferson City
- Gay friendly Hotels in Jefferson City
- Hotels with Early Check-in in Jefferson City
- Hotels with Room Service in Jefferson City
- Non-Smoking Hotels in Jefferson City
- Golf Hotels in Jefferson City
- Romantic Hotels in Jefferson City
- Hotels with Laundry Facilities in Jefferson City
- Hotels on the Lake in Jefferson City
- Hotels with Air Conditioning in Jefferson City
- Hotels with a Pool in Jefferson City
- Fishing Resorts & in Jefferson City
- B&B in Jefferson City
- 5 Star Hotels in Jefferson City
- Apartments in Jefferson City
- Cabin Rentals in Jefferson City
- Motels in Jefferson City
- 4 Star Hotels in Jefferson City
- Cottages in Jefferson City
- 3 Star Hotels in Jefferson City
- Wyndham Hotels in Jefferson City
- Resorts in Jefferson City
- Vacation Homes in Jefferson City
- Marriott Hotels & Resorts in Jefferson City
- Farmstay in Jefferson City
- Flights to Jefferson City
- Flights from Cole County
- Flights from Jefferson City
- Flights from Columbus to Jefferson City
- Flights from Salt Lake City to Jefferson City
- Flights from Newark to Jefferson City
- Flights from Phoenix to Jefferson City
- Flights from Denver to Jefferson City
- Flights from Houston to Jefferson City
- Flights from Rogers to Jefferson City
- Flights from Springfield to Jefferson City
- Flights from Lafayette to Jefferson City
- Flights from Austin to Jefferson City
- Flights from Tampa to Jefferson City
- Flights from Atlanta to Jefferson City
- Flights from Philadelphia to Jefferson City
- Flights from Orlando to Jefferson City
- Flights from Walla Walla to Jefferson City
- Flights from St. Petersburg - Clearwater to Jefferson City
- Flights from Appleton to Jefferson City
- Flights from Charlotte to Jefferson City
- Flights from Richmond to Jefferson City
- Flights from Omaha to Jefferson City
- Flights from Toronto to Jefferson City
- Flights from Fayetteville to Jefferson City
- Flights from Fort Lauderdale to Jefferson City
- Flights from Calgary to Jefferson City
- Flights from Savannah to Jefferson City
- Flights from Boston to Jefferson City
- Flights from Baton Rouge to Jefferson City
- Flights from St. Petersburg to Jefferson City
- Flights from New York to Jefferson City
- Flights from Garden City to Jefferson City
- Flights from Pasco to Jefferson City
- Flights from Fort Myers to Jefferson City
- Flights from Bismarck to Jefferson City
- Flights from Waterloo to Jefferson City
- Flights from Killeen to Jefferson City
- Flights from Los Angeles to Jefferson City
- Flights from San Diego to Jefferson City
- Flights from Spokane to Jefferson City
- Flights from Helsinki to Jefferson City
- Car rentals near Jefferson City
- Enterprise Rental Cars in Jefferson City
- Budget Rental Cars in Jefferson City
- Hertz Rental Cars in Jefferson City
- Avis Rental Cars in Jefferson City
- Van Car Rentals in Jefferson City
- Luxury Car Rentals in Jefferson City
- Alamo Rent A Car Rental Cars in Jefferson City
- National Car Rental Rental Cars in Jefferson City
- Dollar Rent A Car Rental Cars in Jefferson City
- Thrifty Car Rental Rental Cars in Jefferson City
- Rent A Wreck Rental Cars in Jefferson City