A city square with a fountain, modern buildings, and a historic tower.

Resorts & Hotels with Spas in Missouri from $89

Top Cities in Missouri

A cityscape with a prominent historic building featuring arched entrances and a large central dome, surrounded by modern skyscrapers and a well-maintained park with a fountain.
HotelsHotels

Kansas City

Kansas City

Check availability on Missouri Resorts & Hotels with Spas

Our top choices for Missouri hotels with a spa

A spa area with wicker loungers, a stone wall, and a pool.

1. The Elms Hotel & Spa, a Destination by Hyatt Hotel

The Elms Hotel & Spa, a Destination by Hyatt Hotel
4.0 star property
Excelsior Springs
8.8 out of 10, Excellent, (1,004 reviews)
  • cleanliness
    Immerse in a rejuvenating spa retreat with 17 treatment rooms, hot tubs, and beautiful garden views at this historic hotel.
$165 nightly
The price is $180
Nov 10 - Nov 11
Total with taxes and fees
The Elms Hotel & Spa, a Destination by Hyatt Hotel
A hotel room with two beds, a nightstand, a cabinet, and a wall-mounted artwork.

2. Camden on the Lake Resort & Spa

Camden on the Lake Resort & Spa
4.0 star property
Lake Ozark
9.0 out of 10, Wonderful, (1,004 reviews)
  • cleanliness
    Relax at this lakeside resort with four treatment rooms at Spa 54, featuring hot stone massages, hydrotherapy, and couples' services.
$137 nightly
The price is $146
Nov 1 - Nov 2
Total with taxes and fees
Camden on the Lake Resort & Spa
A couple relaxing by a window overlooking a bridge and water.

3. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,003 reviews)
  • cleanliness
    Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
$375 nightly
The price is $438
Oct 13 - Oct 14
Total with taxes and fees
Four Seasons Hotel St Louis
A thatched-roof building with a sign reading "TIKI HUT POOL BAR".

4. Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks
3.0 star property
Osage Beach
8.4 out of 10, Very good, (1,008 reviews)
  • cleanliness
    Lakeside spa resort with golf course offers rejuvenating massages, body treatments, and poolside relaxation.
$164 nightly
The price is $175
Nov 1 - Nov 2
Total with taxes and fees
Margaritaville Lake Resort Lake of the Ozarks
A grand hotel lobby with a central spiral staircase, multiple balconies, and a large indoor plant.

5. Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
St. Charles
8.8 out of 10, Excellent, (1,009 reviews)
$139 nightly
The price is $159
Oct 19 - Oct 20
Total with taxes and fees
Embassy Suites by Hilton St. Louis St. Charles
A rooftop terrace with rows of metal chairs and a view of city buildings.

6. Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis
9.6 out of 10, Exceptional, (3,787 reviews)
$135 nightly
The price is $158
Oct 18 - Oct 19
Total with taxes and fees
Drury Plaza Hotel St. Louis at the Arch
A lobby with a sofa, two armchairs, a coffee table, and a staircase.

7. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4,351 reviews)
$134 nightly
The price is $158
Oct 30 - Oct 31
Total with taxes and fees
Hyatt Regency St. Louis at The Arch
A modern lounge area with a stone fireplace, comfortable seating, and a bar in the background.

8. Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
3.0 star property
Clayton
8.8 out of 10, Excellent, (1,005 reviews)
$118 nightly
The price is $139
Oct 18 - Oct 19
Total with taxes and fees
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
A lobby with a reception desk, blue sofas, a coffee table, and a plant display.

9. Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold
3.0 star property
Arnold
9.6 out of 10, Exceptional, (1,001 reviews)
$126 nightly
The price is $146
Oct 18 - Oct 19
Total with taxes and fees
Drury Inn & Suites St. Louis Arnold
A hotel lobby with seating areas, a fireplace, and a kitchen in the background.

10. Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
Riverport
7.8 out of 10, Good, (1,010 reviews)
$76 nightly
The price is $89
Oct 19 - Oct 20
Total with taxes and fees
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Missouri Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

8/10 Good
"The thing that stands out to us was the attention to us when we first arrived and discovered the air conditioning in the room was not working. It was brought to the hotel maintenance person and determined we needed to be placed in another room. We expected a similar-size room as a replacement but it was a suite they put us in. Very impressive. Breakfast was good and we enjoyed the variety to select from. The process of validating our parking was also easy. I could see some modernization could still be made but it was a good place for us to headquarter for our weekend."
Robert 2-night trip
Posted less than an hour ago
Clayton Plaza Hotel & Extended Stay

Explore a world of travel with Expedia