Title: Santa Cruz Vacation Rentals from $76: Search Short-Term Rentals | Expedia.com

[Santa Cruz Hotels](https://expedia.com/Destinations-In-Santa-Cruz.d738889999009755136.Hotel-Destinations)[Car Rentals in Santa Cruz](https://expedia.com/Destinations-In-Santa-Cruz.d738889999009755136.Car-Rental-Destinations)[Santa Cruz Vacations](https://expedia.com/Santa-Cruz.d738889999009755136.Destination-Travel-Guides)

![Day 1 of of our Galapagos Island Adventure began at Santa Cruz Island.  We approached Black Turtle Cove in our panga boats from our small cruising vessel, and the first sign of wildlife were birds with blue feet.  Yes, the infamous Blue Footed Booby.  It was so exhilarating to see them here. #NationalPark](https://images.trvl-media.com/place/6053725/c9e51eac-dd64-4f7c-bdec-35cb3de03665.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Diagnosis Wanderlust

![](https://images.trvl-media.com/place/6053725/c9e51eac-dd64-4f7c-bdec-35cb3de03665.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Top Cities in Santa Cruz

![The hidden beauty of Playa el Garrapatero Beach on Santa Cruz Island on Galapagos Archipelago](https://images.trvl-media.com/place/602686/a8919a7e-6534-4945-82e3-2c50d465975b.jpg?impolicy=fcrop&w=384&h=216&q=medium)

#### Puerto Ayora

[](https://expedia.com/Puerto-Ayora-Vacation-Rentals.d602686.Travel-Guide-VacationRentals)

## Our top choices for Santa Cruz vacation rentals

![Exterior](https://images.trvl-media.com/lodging/35000000/34940000/34937800/34937768/9468ea94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Suite | 1 bedroom, down comforters, individually furnished, blackout drapes](https://images.trvl-media.com/lodging/35000000/34940000/34937800/34937768/48fd3b45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/35000000/34940000/34937800/34937768/e9355473.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Quadruple Room, 1 Bedroom | 1 bedroom, down comforters, individually furnished, blackout drapes](https://images.trvl-media.com/lodging/35000000/34940000/34937800/34937768/95d1d08f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Suites.h34937768.Hotel-Information)

9.4/10

Exceptional

(24 reviews)

"Check was early and friendly staff Room was super clean and comfortable"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Judy

$92 nightly

$92 total

Mar 4 - Mar 5

[](https://www.expedia.com/Puerto-Ayora-Hotels-Suites.h34937768.Hotel-Information)

![Family Duplex, 2 Bedrooms, Private Bathroom, Garden View (Courtyard ) | Terrace/patio](https://images.trvl-media.com/lodging/17000000/16790000/16786900/16786878/ffb9bce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, Ensuite (One bedroom King) | Premium bedding, pillowtop beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/17000000/16790000/16786900/16786878/34c553bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/17000000/16790000/16786900/16786878/392aa62b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/17000000/16790000/16786900/16786878/aabb8b8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aparthotel in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Torre-Mar-Galapagos-Boutique-Suites.h16786878.Hotel-Information)

9.2/10

Wonderful

(20 reviews)

"Very nice suite, clean, quiet. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Masoud

$114 nightly

$114 total

Mar 7 - Mar 8

[](https://www.expedia.com/Puerto-Ayora-Hotels-Torre-Mar-Galapagos-Boutique-Suites.h16786878.Hotel-Information)

![Luxury Apartment, Balcony | Living area | LCD TV, Netflix, pay movies, streaming services](https://images.trvl-media.com/lodging/107000000/106890000/106882100/106882041/39eae50b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Apartment, Balcony | Living area | LCD TV, Netflix, pay movies, streaming services](https://images.trvl-media.com/lodging/107000000/106890000/106882100/106882041/7209e130.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, Balcony, City View | Balcony](https://images.trvl-media.com/lodging/107000000/106890000/106882100/106882041/5efe3e57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Apartment, Balcony | Balcony](https://images.trvl-media.com/lodging/107000000/106890000/106882100/106882041/992ac688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galapagos-Coliving-Ecuador-Casa-Tuna.h106882041.Hotel-Information)

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galapagos-Coliving-Ecuador-Casa-Tuna.h106882041.Hotel-Information)

![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/f0249e58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/2475343d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, coffee/tea maker, toaster, cookware/dishes/utensils](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/6f52aa05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/95000000/94870000/94862300/94862210/f1c0fb19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Casa-Vacacional-En-Puerto-Ayora.h94862210.Hotel-Information)

10/10

Exceptional

(1 review)

"Nice and beautiful house to stay very impressed "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John

$121 nightly

$121 total

Mar 4 - Mar 5

[](https://www.expedia.com/Puerto-Ayora-Hotels-Casa-Vacacional-En-Puerto-Ayora.h94862210.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100180000/100177100/100177018/e27d3e6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/101000000/100180000/100177100/100177018/8508134b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100180000/100177100/100177018/41f41cf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100180000/100177100/100177018/735d660b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Bienvenido-A-Tu-Hogar-Isleno-En-Galapagos.h100177018.Hotel-Information)

$102 nightly

$102 total

Mar 4 - Mar 5

[](https://www.expedia.com/Puerto-Ayora-Hotels-Bienvenido-A-Tu-Hogar-Isleno-En-Galapagos.h100177018.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/51000000/50890000/50883200/50883187/0d9fc98c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/51000000/50890000/50883200/50883187/236b5ac4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hair dryer, towels, toilet paper](https://images.trvl-media.com/lodging/51000000/50890000/50883200/50883187/2d5538fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, coffee/tea maker, cookware/dishes/utensils, lobster pot](https://images.trvl-media.com/lodging/51000000/50890000/50883200/50883187/80603d6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in PUERTO AYORA SANTA CRUZ GALAPAGOS

[](https://www.expedia.com/Puerto-Ayora-Hotels-Suites-Cerca-Del-Mar.h50883187.Hotel-Information)

8.8/10

Excellent

(5 reviews)

"Really nice place!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sefora

$130 nightly

$170 total

Mar 4 - Mar 5

[](https://www.expedia.com/Puerto-Ayora-Hotels-Suites-Cerca-Del-Mar.h50883187.Hotel-Information)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/103000000/102790000/102780600/102780548/a58537c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/103000000/102790000/102780600/102780548/d3c64b45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, hair dryer, towels, soap](https://images.trvl-media.com/lodging/103000000/102790000/102780600/102780548/b8157967.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/103000000/102790000/102780600/102780548/9e01f48f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aparthotel in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Queen-Bedroom-Suite-ON-THE-Second-High-Floor-AT-Arianas-Galapagos-Hostal.h102780548.Hotel-Information)

$69 nightly

$76 total

Mar 4 - Mar 5

[](https://www.expedia.com/Puerto-Ayora-Hotels-Queen-Bedroom-Suite-ON-THE-Second-High-Floor-AT-Arianas-Galapagos-Hostal.h102780548.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/103000000/102730000/102721900/102721840/9465b582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/103000000/102730000/102721900/102721840/daa6d638.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/103000000/102730000/102721900/102721840/343f2f1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/103000000/102730000/102721900/102721840/5328eb63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Vrbo-Property.h102721840.Hotel-Information)

10/10

Exceptional

(1 review)

"We enjoyed our 6-night stay at Ariana's. The apartment was large and comfortable. Bedroom air conditioners were whisper quiet. We especially enjoyed the rooftop terrace with its soft breezes. It’s a 20 minute walk to the big tortoise statue and a few minutes more to the Mlecon, or a 2 taxi ride."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Dean P.

$89 nightly

$99 total

Mar 4 - Mar 5

[](https://www.expedia.com/Puerto-Ayora-Hotels-Vrbo-Property.h102721840.Hotel-Information)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/111000000/110140000/110134100/110134025/e9b7ef2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/111000000/110140000/110134100/110134025/a5ec6899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/111000000/110140000/110134100/110134025/8b0d2620.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/111000000/110140000/110134100/110134025/c74f8717.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Vrbo-Property.h110134025.Hotel-Information)

10/10

Exceptional

(1 review)

"Perfect start to finish. Very clean! Drinking water provided. The host helped us with a small hiccup regarding our transfer so we were able to catch the ferry to San Cristóbal with no problem. Highly recommend!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Shannyn Z.

$90 nightly

$90 total

Mar 4 - Mar 5

[](https://www.expedia.com/Puerto-Ayora-Hotels-Vrbo-Property.h110134025.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/1f94b12a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Townhome, 1 Bedroom, Non Smoking, City View | 2 bedrooms, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/2847ed9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/2ad1a614.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Townhome, 1 Bedroom, Non Smoking, City View | Living area](https://images.trvl-media.com/lodging/31000000/30410000/30400900/30400811/50aec426.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Villa-Galapagos.h30400811.Hotel-Information)

6.0/10

(1 review)

"着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。"

![Japan](https://a.travel-assets.com/egds/marks/flags/jp.svg)

アオアシカツオドリ

[](https://www.expedia.com/Puerto-Ayora-Hotels-Villa-Galapagos.h30400811.Hotel-Information)

![1 bedroom, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/60000000/59680000/59677200/59677109/1213239e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/60000000/59680000/59677200/59677109/3ed3ea89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/60000000/59680000/59677200/59677109/e5ff1a0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/60000000/59680000/59677200/59677109/b1d46278.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aparthotel in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galarous-Island-Apartments.h59677109.Hotel-Information)

$115 nightly

$115 total

Apr 1 - Apr 2

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galarous-Island-Apartments.h59677109.Hotel-Information)

![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/117000000/116010000/116005500/116005423/c4aabc94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/117000000/116010000/116005500/116005423/7b3c7f31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/117000000/116010000/116005500/116005423/b385e31e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, cookware/dishes/utensils, spices, dining tables](https://images.trvl-media.com/lodging/117000000/116010000/116005500/116005423/592985cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Unknown

[](https://www.expedia.com/Puerto-Ayora-Hotels-Vrbo-Property.h116005423.Hotel-Information)

$106 nightly

$106 total

Mar 17 - Mar 18

[](https://www.expedia.com/Puerto-Ayora-Hotels-Vrbo-Property.h116005423.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/113000000/112680000/112676500/112676466/a8ae6adc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/113000000/112680000/112676500/112676466/e8965b4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/113000000/112680000/112676500/112676466/6bc82d4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112680000/112676500/112676466/9a885418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Cozy-2-Bedroom-Apartment-In-Charming-Puerto-Ayora-With-AC.h112676466.Hotel-Information)

$102 nightly

$102 total

Mar 19 - Mar 20

[](https://www.expedia.com/Puerto-Ayora-Hotels-Cozy-2-Bedroom-Apartment-In-Charming-Puerto-Ayora-With-AC.h112676466.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/ebf60a8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/753f38a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/46b3f49b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/40000000/39990000/39987500/39987421/d7cc9d58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Two-Bedroom-House-The-Galapagos-Pearl-Hotel.h39987421.Hotel-Information)

10/10

Exceptional

(1 review)

"We stayed 3 nights in the "casa grande" associated with the Galapagos Pearl Hotel and could not have been more pleased. The casa has 2 bedrooms, a small kitchen, one bathroom, and is conveniently located right next to the pool and the outdoor dining area where Yolanda serves breakfast. Your room is cleaned every day. The garden surrounding the pool and casa is lush and full of geckos, cats, and beautiful plantings. Yolanda is from the Galapagos, she is a wonderful host and her daughter helped us...

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Laura E.

$227 nightly

$251 total

Mar 4 - Mar 5

[](https://www.expedia.com/Puerto-Ayora-Hotels-Two-Bedroom-House-The-Galapagos-Pearl-Hotel.h39987421.Hotel-Information)

![1 bedroom, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/61000000/60600000/60597200/60597196/fae3fe2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/61000000/60600000/60597200/60597196/f6bbb628.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/61000000/60600000/60597200/60597196/9ae4b365.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/61000000/60600000/60597200/60597196/ecab4b80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galarous-Serve-You-With-Quality-And-Warmth-In-Your-Home.h60597196.Hotel-Information)

$99 nightly

$99 total

Apr 1 - Apr 2

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galarous-Serve-You-With-Quality-And-Warmth-In-Your-Home.h60597196.Hotel-Information)

![1 bedroom, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/60000000/59690000/59688700/59688686/82ca6a97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/60000000/59690000/59688700/59688686/ce69d14a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/60000000/59690000/59688700/59688686/4b47b389.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/60000000/59690000/59688700/59688686/a7583985.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galarous-Servirle-Con-Calidad-Y-Calidez-En-Su-Casa.h59688686.Hotel-Information)

$49 nightly

$49 total

Mar 4 - Mar 5

[](https://www.expedia.com/Puerto-Ayora-Hotels-Galarous-Servirle-Con-Calidad-Y-Calidez-En-Su-Casa.h59688686.Hotel-Information)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/104000000/103060000/103058600/103058515/406de75c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/104000000/103060000/103058600/103058515/6408dac0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/104000000/103060000/103058600/103058515/cb5f3162.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/104000000/103060000/103058600/103058515/7a5abddd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-TWO-Bedrooms-Apartment-ON-THE-First-Floor-IN-Arianas-Galapagos-Hostal.h103058515.Hotel-Information)

$89 nightly

$99 total

Mar 4 - Mar 5

[](https://www.expedia.com/Puerto-Ayora-Hotels-TWO-Bedrooms-Apartment-ON-THE-First-Floor-IN-Arianas-Galapagos-Hostal.h103058515.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/102000000/101740000/101738700/101738687/734f5e24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/102000000/101740000/101738700/101738687/5646c61b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/102000000/101740000/101738700/101738687/ecbf06a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, stereo](https://images.trvl-media.com/lodging/102000000/101740000/101738700/101738687/0cd636bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-Endemic-Suite-Apartamento-Con-Azotea-Vista-360.h101738687.Hotel-Information)

$85 nightly

$85 total

Mar 4 - Mar 5

[](https://www.expedia.com/Puerto-Ayora-Hotels-Endemic-Suite-Apartamento-Con-Azotea-Vista-360.h101738687.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/113000000/112680000/112677400/112677301/ac8a7bfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books](https://images.trvl-media.com/lodging/113000000/112680000/112677400/112677301/ee9d32a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/113000000/112680000/112677400/112677301/4e605901.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/113000000/112680000/112677400/112677301/3200cd5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-2-Bedroom-Apartment-With-AC.h112677301.Hotel-Information)

$88 nightly

$88 total

Mar 4 - Mar 5

[](https://www.expedia.com/Puerto-Ayora-Hotels-2-Bedroom-Apartment-With-AC.h112677301.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/83000000/82560000/82555500/82555432/aa67740e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/83000000/82560000/82555500/82555432/77881106.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/83000000/82560000/82555500/82555432/2ebaba6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/83000000/82560000/82555500/82555432/537886f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Puerto Ayora

[](https://www.expedia.com/Puerto-Ayora-Hotels-FAMILY-SUITE-In-Puerto-Ayora.h82555432.Hotel-Information)

10/10

Exceptional

(1 review)

"Great lodging with effective space for multiple groups of travelers. Location is perfect, off the tourist path, and easy to access by any taxis in Puerto Arroyo (just say you want to go to Parque Cascada). Groceries are available anywhere near the house, better produce quality found in the shops on Baltra Ave. Property manager is easy to communicate with and responds instantly."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nathan M.

$225 nightly

$225 total

Mar 7 - Mar 8

[](https://www.expedia.com/Puerto-Ayora-Hotels-FAMILY-SUITE-In-Puerto-Ayora.h82555432.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-17&endDate=2026-03-18&regionId=738889999009755136&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

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## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+Gal%C3%A1pagos%2C+Ecuador&regionId=738889999009755136&latLong=0.06125%2C-90.563656&adults=2&startDate=2026-05-31&d1=2026-05-31&endDate=2026-06-03&d2=2026-06-03&lodging=CABIN)

Villas

[](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+Gal%C3%A1pagos%2C+Ecuador&regionId=738889999009755136&latLong=0.06125%2C-90.563656&adults=2&startDate=2026-05-31&d1=2026-05-31&endDate=2026-06-03&d2=2026-06-03&lodging=VILLA)

Aparthotels

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Apartments

[](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+Gal%C3%A1pagos%2C+Ecuador&regionId=738889999009755136&latLong=0.06125%2C-90.563656&adults=2&startDate=2026-05-31&d1=2026-05-31&endDate=2026-06-03&d2=2026-06-03&lodging=APARTMENT)

Condos

[](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+Gal%C3%A1pagos%2C+Ecuador&regionId=738889999009755136&latLong=0.06125%2C-90.563656&adults=2&startDate=2026-05-31&d1=2026-05-31&endDate=2026-06-03&d2=2026-06-03&lodging=CONDO)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+Gal%C3%A1pagos%2C+Ecuador&regionId=738889999009755136&latLong=0.06125%2C-90.563656&adults=2&startDate=2026-05-31&d1=2026-05-31&endDate=2026-06-03&d2=2026-06-03&lodging=VACATION_HOME)

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## Top Santa Cruz Hotel Reviews

![Posada del Mar](https://images.trvl-media.com/lodging/42000000/41950000/41941800/41941787/e7fb3ff1_y.jpg)

### Posada del Mar

10/10 Excellent

"Great Staff!"

[](https://expedia.com/Puerto-Ayora-Hotels-Posada-Del-Mar.h41941787.Hotel-Information)

![El Barranco Galapagos](https://images.trvl-media.com/lodging/112000000/111510000/111508100/111508035/910f927d_y.jpg)

### El Barranco Galapagos

10/10 Excellent

"Beautiful room, pristine location, staff is professional and at your service."

[](https://expedia.com/Puerto-Ayora-Hotels-Hotel-Barranco-Galapagos.h111508035.Hotel-Information)

![Ikala Galapagos Hotel](https://images.trvl-media.com/lodging/24000000/23690000/23688400/23688395/ecbf00ed_y.jpg)

### Ikala Galapagos Hotel

10/10 Excellent

"Amazing hotel, clean and beautiful. Special thanks for the attentive young man on reception. The hotel is close to everything, beautiful room and bathroom. Nice view of the pool. I enjoyed my drink on the rooftop at night as well. "

[](https://expedia.com/Puerto-Ayora-Hotels-Ikala-Galapagos-Hotel.h23688395.Hotel-Information)

![Capitan Max B&B](https://images.trvl-media.com/lodging/15000000/14720000/14716700/14716616/7e3fbe48_y.jpg)

### Capitan Max B&B

10/10 Excellent

"My husband and I LOVED our stay! The owners are incredibly friendly and helpful- they were able to answer questions about transportation, dining recommendations, and more. There was a delicious homemade breakfast every morning. The rooms are spacious and very clean. They even helped us book our inter island ferries. The location is also perfect- quiet street but right next to everything you need in Puerto Ayora. If you’re staying on Santa Cruz, you will not regret booking here!"

[](https://expedia.com/Puerto-Ayora-Hotels-Capitan-Max-BB.h14716616.Hotel-Information)

![Royal Palm Galapagos, Curio Collection Hotel by Hilton](https://images.trvl-media.com/lodging/13000000/12540000/12535100/12535025/215f955b_y.jpg)

### Royal Palm Galapagos, Curio Collection Hotel by Hilton

10/10 Excellent

"We had the best time ever! We will definitely be back! The place is beautiful!"

[](https://expedia.com/Santa-Rosa-Hotels-The-Royal-Palm-Hotel.h12535025.Hotel-Information)

![Galapagos Dreams](https://images.trvl-media.com/lodging/12000000/11700000/11698100/11698055/6897639d_y.jpg)

### Galapagos Dreams

10/10 Excellent

"Great staff, incredibly helpful."

[](https://expedia.com/Puerto-Ayora-Hotels-GALAPAGOS-DREAMS.h11698055.Hotel-Information)

![Maidith Galapagos Inn](https://images.trvl-media.com/lodging/89000000/88480000/88474700/88474681/1dd0538f_y.jpg)

### Maidith Galapagos Inn

10/10 Excellent

"We had a wonderful stay at this small, family-owned hotel in the Galápagos. The service was exceptional from start to finish — the owner personally made sure every detail was taken care of and that we had everything we needed. The staff spoke excellent English, which made communication easy and stress-free. The location was perfect, close to everything yet still quiet and relaxing. And the breakfasts were fantastic — fresh, generous, and a great way to start each day of exploring. We truly felt welcomed and cared for. Highly recommend! You will not be disappointed!"

[](https://expedia.com/Puerto-Ayora-Hotels-Maidith-Galapagos-Inn.h88474681.Hotel-Information)

![Galapagos Verde Azul](https://images.trvl-media.com/lodging/10000000/9580000/9577600/9577577/6a115ff5_y.jpg)

### Galapagos Verde Azul

10/10 Excellent

"The rooms were big and well kept. The staff was awesome. The location was quiet and we could walk to the beach. "

[](https://expedia.com/Puerto-Ayora-Hotels-Galapagos-Verde-Azul.h9577577.Hotel-Information)

![Hotel Fiesta](https://images.trvl-media.com/lodging/10000000/9700000/9690700/9690626/b440b32f_y.jpg)

### Hotel Fiesta

10/10 Excellent

"Everything was wonderful, rooms are small but we hardly spent any time in it and the bed was just fine to fall asleep on after a long day of adventures! Rooms are well cleaned as well towels. Pool area is great, location is nice and quiet but easy walking distance to anything. "

[](https://expedia.com/Puerto-Ayora-Hotels-Hotel-Fiesta.h9690626.Hotel-Information)

## Find out more about Santa Cruz

## Discover your perfect Santa Cruz vacation rental with Expedia

#### How many vacation rentals are available in Santa Cruz? 
  
Expedia has plenty of vacation rentals to choose from in and around Santa Cruz, so you’re guaranteed to find the right one for you. 
  
#### How much is a vacation rental in Santa Cruz? 
  
The selection of Santa Cruz vacation rentals we have selected for you start as low as $76 per night. Entering your travel dates in the search wizard you might find even better deals! 
  
#### What type of vacation rental can I get in Santa Cruz? 
  
Vacation rentals in Santa Cruz come in all shapes and sizes, and your options depend on your chosen travel dates. You could entertain in a blissful vacation home, chill in a private apartment, or find family fun at a resort. Expedia offers a superb choice of Santa Cruz vacation rentals to suit everyone. 
  
#### Why should I choose a vacation rental in Santa Cruz? 
  
 Expedia’s vacation rentals provide cozy comforts you can sink into on your own schedule. You’ll enjoy your own space in a property with a kitchen, a pool, a garden etc. Maybe you’ll prefer somewhere with a spa or kids activities. A Santa Cruz vacation rental often works out to be a fantastic, cost-effective option for [groups](https://www.expedia.com/lp/b/vr/large) and [families](https://www.expedia.com/lp/b/vr/family) visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. 
  
#### How do I find the best deal on a vacation rental in Santa Cruz? 
  
 Find vacation rentals in Santa Cruz by viewing Expedia’s latest deals, or enter your travel dates and use the filters to select by amenities, price, or rating. Dive into the reviews to get a true feeling of which is your favorite vacation rental in Santa Cruz. 
  
#### What amenities are available in a vacation rental in Santa Cruz? 
  
 The choice is yours! Perhaps you love cooking in a well-equipped kitchen. Or maybe a late breakfast and a [swimming pool](https://www.expedia.com/lp/b/vr/private-pool) is more your thing. Of course, there’s always the treat of having [your own hot tub](https://www.expedia.com/lp/b/vr/hot-tub). Expedia has a vast range of amenities in Santa Cruz vacation rentals designed to suit every budget and trip type. 
  
#### When is the best time to stay in a vacation rental in Santa Cruz? 
  
 Everytime is a great time to head to Santa Cruz! Staying in a Santa Cruz vacation rentals you will always find lots going on to keep you entertained. 
  
#### Why book a vacation rental with Expedia? 
  
 Expedia has locked in amazing deals on a huge selection of impressive vacation rentals in Santa Cruz. We give you the information and inspiration you need all in one place. With so many properties to choose from, you know you can book your perfect Santa Cruz vacation rental with confidence. ANd don’t forget, if you bundle with a flight or a car rental in Santa Cruz, you can save even more. 
  
#### Can I cancel my vacation rental through Expedia? 
  
 Yes, you can cancel or change your Santa Cruz vacation rental by contacting your property manager directly. Contact details are easy to find on your itinerary in Trips. For more information, check out our Customer Service Portal and we’ll help you get everything sorted. 
  
## Explore a world of travel with Expedia

- Popular Santa Cruz Cities

- [Puerto Ayora Vacation Rentals ](https://expedia.com/Puerto-Ayora-Vacation-Rentals.d602686.Travel-Guide-VacationRentals)
- [Baltra Vacation Rentals ](https://expedia.com/Baltra-Vacation-Rentals.d6223000.Travel-Guide-VacationRentals)