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Vacation Rentals in Santa Cruz

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Top Cities in Santa Cruz

Our top choices for Santa Cruz vacation rentals

Torre Mar Galapagos Boutique Suites

Torre Mar Galapagos Boutique Suites
3.0 star property
Puerto Ayora
9.0 out of 10, Wonderful, (17 reviews)
"We had an absolutely wonderful stay at Torre Mar Galápagos and couldn’t recommend it more highly. The apartment-hotel was exactly as advertised—clean, comfortable, and thoughtfully set up for families. We stayed in a two-bedroom unit that provided plenty of space for us and our two teenage kids, making it easy to relax after busy days exploring the islands. Our room was on the top floor, which might be challenging for elderly guests or families with very young children, but it was perfectly...
United States
Gina
$114 nightly
The price is $114
Jan 11 - Jan 12
Torre Mar Galapagos Boutique Suites

Galapagos Coliving Ecuador Casa Tuna

Galapagos Coliving Ecuador Casa Tuna
3.0 star property
Puerto Ayora
Galapagos Coliving Ecuador Casa Tuna

Queen Bedroom Suite ON THE Second High Floor AT Ariana`s Galapagos Hostal

Queen Bedroom Suite ON THE Second High Floor AT Ariana`s Galapagos Hostal
Puerto Ayora
$69 nightly
The price is $76
Jan 11 - Jan 12
Queen Bedroom Suite ON THE Second High Floor AT Ariana`s Galapagos Hostal

Casa Vacacional en Puerto Ayora, Santa Cruz, Galápagos

Casa Vacacional en Puerto Ayora, Santa Cruz, Galápagos
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Nice and beautiful house to stay very impressed "
United States
John
$110 nightly
The price is $110
Jan 14 - Jan 15
Casa Vacacional en Puerto Ayora, Santa Cruz, Galápagos

¡Bienvenido a tu hogar isleño en Galápagos!

¡Bienvenido a tu hogar isleño en Galápagos!
Puerto Ayora
$102 nightly
The price is $102
Jan 20 - Jan 21
¡Bienvenido a tu hogar isleño en Galápagos!

Charming studio in Puerto Ayora with all the services for a comfortable stay

Charming studio in Puerto Ayora with all the services for a comfortable stay
Puerto Ayora
$86 nightly
The price is $86
Jan 15 - Jan 16
Charming studio in Puerto Ayora with all the services for a comfortable stay

Apartment near the Sea

Apartment near the Sea
PUERTO AYORA SANTA CRUZ GALAPAGOS
8.8 out of 10, Excellent, (5 reviews)
"Really nice place!"
United States
Sefora
$130 nightly
The price is $170
Jan 11 - Jan 12
Apartment near the Sea

Jardin de Galápagos.

Jardin de Galápagos.
Galápagos Islands
$113 nightly
The price is $121
Jan 19 - Jan 20
Jardin de Galápagos.

This two-bedroom is a perfect island getaway.

This two-bedroom is a perfect island getaway.
Puerto Ayora, Santa Cruz Island
8.8 out of 10, Excellent, (5 reviews)
"Donna communicated with us before our trip to provide information about arrival and to offer transportation assistance from the airport. Once we were there she offered to arrange tours, suggest dining places and made reservations for us. She did everything she could to make our stay easy and enjoyable. On one of the tours she was our guide. That was so helpful."
United States
Cynthia H.
$175 nightly
The price is $198
Jan 11 - Jan 12
This two-bedroom is a perfect island getaway.

The Oceanview two-bedroom with balcony

The Oceanview two-bedroom with balcony
Puerto Ayora, Santa Cruz Island
10.0 out of 10, Exceptional, (25 reviews)
"Comfortable stay for a family of 4 with the 2 bedrooms. Well equipped kitchen although we did not use much. Easy walk to the port for ferries and tours. Several dining options with 10 min walk. 4 th floor stay was nice with lots of natural breeze "
United States
Visweswaren
$214 nightly
The price is $243
Jan 11 - Jan 12
The Oceanview two-bedroom with balcony

Spacious 6-bedroom building in superb Puerto Ayora with AC

Spacious 6-bedroom building in superb Puerto Ayora with AC
2.0 star property
Puerto Ayora
$60 nightly
The price is $66
Jan 11 - Jan 12
Spacious 6-bedroom building in superb Puerto Ayora with AC

Galarous serve you with quality and warmth in your home

Galarous serve you with quality and warmth in your home
Puerto Ayora
$120 nightly
The price is $120
Jan 11 - Jan 12
Galarous serve you with quality and warmth in your home

Galarous island apartments

Galarous island apartments
Puerto Ayora
$130 nightly
The price is $130
Jan 11 - Jan 12
Galarous island apartments

Courtyard Studio perfect for an active Galapagos adventure

Courtyard Studio perfect for an active Galapagos adventure
Puerto Ayora
$145 nightly
The price is $164
Jan 11 - Jan 12
Courtyard Studio perfect for an active Galapagos adventure

One Bedroom with private balcony

One Bedroom with private balcony
2.0 star property
Puerto Ayora, Santa Cruz Island
$145 nightly
The price is $164
Jan 11 - Jan 12
One Bedroom with private balcony

KING SIZE BED & TWIN SIZE BED WITH PRIVATE BATHROOM ON SECOND FLOOR

KING SIZE BED & TWIN SIZE BED WITH PRIVATE BATHROOM ON SECOND FLOOR
Puerto Ayora
$50 nightly
The price is $55
Jan 18 - Jan 19
KING SIZE BED & TWIN SIZE BED WITH PRIVATE BATHROOM ON SECOND FLOOR

KING-SIZE BED OR TWO TWIN BEDS SUITE ON SECOND FLOOR WITH CITY VIEW BALCONY

KING-SIZE BED OR TWO TWIN BEDS SUITE ON SECOND FLOOR WITH CITY VIEW BALCONY
Puerto Ayora
$60 nightly
The price is $66
Jan 11 - Jan 12
KING-SIZE BED OR TWO TWIN BEDS SUITE ON SECOND FLOOR WITH CITY VIEW BALCONY

Ocean view Penthouse

Ocean view Penthouse
2.0 star property
Puerto Ayora, Santa Cruz Island
10.0 out of 10, Exceptional, (1 review)
"We enjoyed our stay. The air conditioning was a welcome retreat after a day spent exploring. The views are amazing. "
United States
Greta S.
$180 nightly
The price is $204
Jan 11 - Jan 12
Ocean view Penthouse

Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi

Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi
Puerto Ayora
$102 nightly
The price is $102
Jan 15 - Jan 16
Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi

Dominga Terrace

Dominga Terrace
Unknown
$106 nightly
The price is $106
Jan 11 - Jan 12
Dominga Terrace
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Find out more about Santa Cruz

Discover your perfect Santa Cruz vacation rental with Expedia

How many vacation rentals are available in Santa Cruz?


Expedia has plenty of vacation rentals to choose from in and around  Santa Cruz, so you’re guaranteed to find the right one for you. 


How much is a vacation rental in Santa Cruz?


The selection of Santa Cruz vacation rentals we have selected for you start as low as $76 per night. Entering your travel dates in the search wizard you might find even better deals!


What type of vacation rental can I get in Santa Cruz?


Vacation rentals in Santa Cruz come in all shapes and sizes, and your options depend on your chosen travel dates. You could entertain in a blissful vacation home, chill in a private apartment, or find family fun at a resort. Expedia offers a superb choice of Santa Cruz vacation rentals to suit everyone. 


Why should I choose a vacation rental in Santa Cruz?


Expedia’s vacation rentals provide cozy comforts you can sink into on your own schedule. You’ll enjoy your own space in a property with a kitchen, a pool, a garden etc. Maybe you’ll prefer somewhere with a spa or kids activities. A Santa Cruz vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. 


How do I find the best deal on a vacation rental in Santa Cruz?


Find vacation rentals in Santa Cruz by viewing Expedia’s latest deals, or enter your travel dates and use the filters to select by amenities, price, or rating. Dive into the reviews to get a true feeling of which is your favorite vacation rental in Santa Cruz.  


What amenities are available in a vacation rental in Santa Cruz?


The choice is yours! Perhaps you love cooking in a well-equipped kitchen. Or maybe a late breakfast and a swimming pool is more your thing. Of course, there’s always the treat of having your own hot tub. Expedia has a vast range of amenities in Santa Cruz vacation rentals designed to suit every budget and trip type.


When is the best time to stay in a vacation rental in Santa Cruz?   


Everytime is a great time to head to Santa Cruz! Staying in a Santa Cruz vacation rentals you will always find lots going on to keep you entertained. 


Why book a vacation rental with Expedia?


Expedia has locked in amazing deals on a huge selection of impressive vacation rentals in Santa Cruz. We give you the information and inspiration you need all in one place. With so many properties to choose from, you know you can book your perfect Santa Cruz vacation rental with confidence. ANd don’t forget, if you bundle with a flight or a car rental in Santa Cruz, you can save even more.


Can I cancel my vacation rental through Expedia?  


Yes, you can cancel or change your Santa Cruz vacation rental by contacting your property manager directly. Contact details are easy to find on your itinerary in Trips. For more information, check out our Customer Service Portal and we’ll help you get everything sorted.