Name: Ciel y Miel
Price range: $228 total
Rating: 10

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Your Eastern Panama Vacation

Leave all the planning to us with an Eastern Panama vacation package. With everything organized before you jet off, all you need to do is sit back, chill out and experience this destination's many wonders. Where to start your journey? In the most popular cities, of course. Isla Tigre and Palenque are two great places to kick off your itinerary during your trip to Eastern Panama. When it's time to stop daydreaming and start doing, Expedia will help turn your Eastern Panama vacation into reality.

The Latest Eastern Panama vacation packages

Price found within the past 48 hours. Click for updated prices.

Villa Marina Hotel

$741

per person

Jul 29 - Aug 2

found 1 day ago

Roundtrip flight included

Miami (MIA) to Panama City (PTY)

9/10 Wonderful! (161 reviews)

The room was spotless clean! The staff was always helpful and ready to serve. Breakfast and food in general was very tasty. The Bar is quite complete

Reviewed on Jun 13, 2026

Central Hotel Panama Casco Viejo

Casco Viejo

Save 100% on your flight

$1,078

per person

Sep 5 - Sep 12

found 1 day ago

Roundtrip flight included

Bridgetown (BGI) to Panama City (PTY)

9.2/10 Wonderful! (1,008 reviews)

I really enjoyed the hotel. I enjoyed the food, drinks and entertainment. The pool was another matter, for such a top rated hotel the pool was worse than any other hotel I have stayed. In the pictures it looked beautiful but when we went up, it was very disappointed. Everything else was great. I really picked you guys because of the pool. I wanted to get in a pool but yours like I said disappointed me.

Reviewed on Jun 19, 2026

Megapolis Hotel Panamá

San Francisco

Save 100% on your flight

$1,004

per person

Sep 5 - Sep 12

found 1 day ago

Roundtrip flight included

Bridgetown (BGI) to Panama City (PTY)

8.4/10 Very Good! (1,553 reviews)

Convenient location & very good overall!

Reviewed on Jun 20, 2026

Hotel Riu Plaza Panama

Bella Vista

$936

per person

Sep 5 - Sep 12

found 1 day ago

Roundtrip flight included

Bridgetown (BGI) to Panama City (PTY)

9/10 Wonderful! (5,582 reviews)

The facility including the room were clean. The staff was kind. The breakfast was amazing with so many choices!

Reviewed on Jun 21, 2026

Casa Mallet by Wynwood House

Casco Viejo

$1,310

per person

Aug 9 - Aug 15

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

9.8/10 Exceptional! (27 reviews)

In the middle of the old town, lovely rooftop. Beautiful apartment. Easy check in. WhatsApp line is available if anything was needed or if we had questions.

Reviewed on Mar 12, 2026

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Discover the most popular places to visit in Eastern Panama

Museum of the Kuna Nation

You can spend an afternoon studying the exhibits at Museum of the Kuna Nation in Narganá. Stroll along the seaside or experience the area's festivals.

Porvenir Museum

You can spend time browsing the exhibits at Porvenir Museum during your travels in Narganá. Amble around the area's seaside or experience its festivals.

Eastern Panama Hotel Deals

Ordovician Beach Resort

Isla Grande Isla Grande Colon

$416 nightly

$459 total

Jun 23 - Jun 24

Total with taxes and fees

10/10 Exceptional! (10 reviews)

"El hotel es una belleza, todo estaba extremadamente limpio, las habitaciones y áreas comunes súper cómodas. La atención de todo el personal es del más alto nivel y te hacen sentir como en casa. Las atracciones también son muy buenas y la comida excepcional."

Reviewed on Jun 8, 2026

san blas luxury tour

guna yala Nusatupo Guna Yala

$144 nightly

$159 total

Jun 23 - Jun 24

Total with taxes and fees

Ciel y Miel

Caillle Principale Cacique Provincia de Colón

Fully refundableReserve now, pay when you stay

$207 nightly

$228 total

Jun 23 - Jun 24

Total with taxes and fees

10/10 Exceptional! (10 reviews)

"The views from this mountain-top boutique hotel are extraordinary."

Reviewed on Feb 1, 2026

See all 186 properties in Eastern Panama

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.