A calm sea with a small boat and a row of palm trees on the shore.

Eastern Panama Vacation Rentals

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Check prices for these dates

In two weeks
Oct 16 - Oct 18
In two months
Nov 27 - Nov 29
In three months
Dec 25 - Dec 27
In four months
Jan 22 - Jan 24

Our top choices for Eastern Panama vacation rentals

A tropical beach with clear turquoise waters, palm trees, and a small island with buildings.

1. san blas luxury tour

san blas luxury tour
2.0 star property
Nusatupo
$92 nightly
The price is $101
Oct 2 - Oct 3
Total with taxes and fees
san blas luxury tour
A beach with palm trees, a thatched-roof hut, and a sandy shore.

2. Beachfront Cabin on the San Blas Islands: Aroma

Beachfront Cabin on the San Blas Islands: Aroma
Guna Yala
$164 nightly
The price is $164
Oct 1 - Oct 2
Total with taxes and fees
Beachfront Cabin on the San Blas Islands: Aroma
A beach with clear turquoise water, a wooden structure with a red roof, and a white sandy shore.

3. Pelicano Island

Pelicano Island
2.0 star property
Moraquedub
$324 nightly
The price is $356
Oct 1 - Oct 2
Total with taxes and fees
Pelicano Island
A coconut on a wooden table under a wooden structure by the beach with palm trees and the ocean in the background.

4. Sanblastourgy

Sanblastourgy
2.0 star property
Nargana
$203 nightly
The price is $223
Oct 1 - Oct 2
Total with taxes and fees
Sanblastourgy
A beach with clear water and a distant island.

5. San Blas Tour Aridub

San Blas Tour Aridub
2.0 star property
Narganá
$226 nightly
The price is $249
Oct 1 - Oct 2
Total with taxes and fees
San Blas Tour Aridub
A tropical beach with palm trees and clear turquoise waters.

6. San Blas Private Oceanfront Cabin

San Blas Private Oceanfront Cabin
2.5 star property
Narganá
$350 nightly
The price is $385
Oct 1 - Oct 2
Total with taxes and fees
San Blas Private Oceanfront Cabin
A thatched-roof overwater bungalow with a wooden deck, clear blue water, and a distant mountain range.

7. San Blas Private Beach Cabin

San Blas Private Beach Cabin
2.5 star property
Narganá
$268 nightly
The price is $295
Oct 1 - Oct 2
Total with taxes and fees
San Blas Private Beach Cabin
A wooden pier leading to a beach with clear turquoise water, surrounded by palm trees and a small building with a balcony.

8. Private Over-Water Cabins on San Blas Island

Private Over-Water Cabins on San Blas Island
2.5 star property
Narganá
$300 nightly
The price is $330
Oct 1 - Oct 2
Total with taxes and fees
Private Over-Water Cabins on San Blas Island
A tent with a view of a beach and palm trees, a red umbrella, and a wooden deck.

9. glampling sanblas luxury

glampling sanblas luxury
1.0 star property
Nargana
$342 nightly
The price is $376
Oct 2 - Oct 3
Total with taxes and fees
glampling sanblas luxury
A hammock on a beach with palm trees and a clear view of the ocean.

10. Private Over-the-Water Cabin in San Blas including Meals

Private Over-the-Water Cabin in San Blas including Meals
2.5 star property
Mirladub
$486 nightly
The price is $535
Oct 2 - Oct 3
Total with taxes and fees
Private Over-the-Water Cabin in San Blas including Meals
A covered outdoor dining area with a view of the beach and palm trees.

11. Caribbean getaway: beach cottage just on the sand

Caribbean getaway: beach cottage just on the sand
Palenque
9.0 out of 10, Wonderful, (4 reviews)
"the view is beautiful! We were taken care of well."
United States
Mirelys
$316 nightly
The price is $316
Oct 1 - Oct 2
Total with taxes and fees
Caribbean getaway: beach cottage just on the sand
A beach with palm trees and a clear view of the ocean.

12. All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama

All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama
Guna Yala Comarca
$842 nightly
The price is $842
Oct 5 - Oct 6
Total with taxes and fees
All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama
A modern house with a covered patio, a lawn, and a view of the surrounding landscape.

13. Lovely Caribbean Apartment with AC + Wifi + BBQ + Beach + Kitchen + Parking

Lovely Caribbean Apartment with AC + Wifi + BBQ + Beach + Kitchen + Parking
Puerto Lindo
$257 nightly
The price is $257
Oct 1 - Oct 2
Total with taxes and fees
Lovely Caribbean Apartment with AC + Wifi + BBQ + Beach + Kitchen + Parking
A tropical beach with palm trees and clear turquoise waters.

14. San Blas Private Over-the-Water Cabin

San Blas Private Over-the-Water Cabin
2.5 star property
Narganá
8.0 out of 10, Very good, (2 reviews)
"I liked the modern payment system that was used for booking the trip, the food was great, the location was as described. I disliked the communication with the reseller this booking goes through. They dropped the ball on communicating pickup time and itinerary confirmation, even when i tried calling and emailing them. I also disliked the value of what you get with this trip. Id expect better cleanliness and standards for this trip. I also disliked when the staff on the island said i needed to pay...
United States
Andrew
$342 nightly
The price is $376
Oct 1 - Oct 2
Total with taxes and fees
San Blas Private Over-the-Water Cabin
A modern cabin with a sloped roof, surrounded by trees, and a gravel path leading to the entrance.

15. Tiny Cabin

Tiny Cabin
3.0 star property
Panamá
10.0 out of 10, Exceptional, (1 review)
$134 nightly
The price is $147
Oct 1 - Oct 2
Total with taxes and fees
Tiny Cabin
A covered outdoor seating area with two chairs and a table, surrounded by vegetation and a stone wall.

16. Cozy Cabin in the Misty Mountain

Cozy Cabin in the Misty Mountain
Panamá
$115 nightly
The price is $115
Oct 1 - Oct 2
Total with taxes and fees
Cozy Cabin in the Misty Mountain
A modern living room with a dining area, a pool table, a TV, and a wall decorated with vinyl records.

17. Elegance and comfort in old town panama

Elegance and comfort in old town panama
Panamá
2.0 out of 10, (1 review)
"The address that’s depicted is not accurate to the map that’s shown and I tried multiple times to communicate with the host and no response"
United States
PAMELA
$90 nightly
The price is $90
Oct 1 - Oct 2
Total with taxes and fees
Elegance and comfort in old town panama
A modern living room with a sofa, a dining table with placemats, and a view of the outdoors through a large window.

18. Cozy and Safe Environment Close to the Airport.

Cozy and Safe Environment Close to the Airport.
Panamá
$82 nightly
The price is $82
Oct 1 - Oct 2
Total with taxes and fees
Cozy and Safe Environment Close to the Airport.
A room with a bed, a bedside table with a tray of cups, a bench with a cushion, and a wooden partition.

19. Beautiful 2-bedroom apartment in Cerro Azul for your jungle getaway

Beautiful 2-bedroom apartment in Cerro Azul for your jungle getaway
Panamá
$140 nightly
The price is $140
Oct 1 - Oct 2
Total with taxes and fees
Beautiful 2-bedroom apartment in Cerro Azul for your jungle getaway
A dining table with a floral tablecloth, wooden chairs, and a kitchen in the background.

20. La Husseyenda. Private Birdwatching Retreat in Cerro Azul’s Mountains in Panama

La Husseyenda. Private Birdwatching Retreat in Cerro Azul’s Mountains in Panama
Panamá
$286 nightly
The price is $286
Oct 1 - Oct 2
Total with taxes and fees
La Husseyenda. Private Birdwatching Retreat in Cerro Azul’s Mountains in Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Eastern Panama Hotel Reviews

Ranchos de Chalia

Ranchos de Chalia

8/10 Good
"The hotel is a sleepy bed breakfast located close to the coast next to a tiny village. The property is older it could do a facelift. The single rooms are small, but functional. The air condition worked great. The pool was a big plus .The staff was very helpful and accommodating. My biggest concern was lack of communication when we tried via Expedia to get more information about directions and check-in. However, it worked ok in the end."
Otto 3-night trip
Posted 9 days ago
Ranchos de Chalia

Find out more about Eastern Panama

Everything you need to know about Eastern Panama vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Eastern Panama vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Eastern Panama vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Eastern Panama vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Eastern Panama. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Eastern Panama in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $101 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Eastern Panama rentals

At Expedia, we put the best Eastern Panama vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Eastern Panama rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Eastern Panama vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Eastern Panama. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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