Title: Eastern Panama Vacation Rentals from $144: Search Short-Term Rentals | Expedia.com

[Eastern Panama Travel Guide](https://expedia.com/Eastern-Panama.dx6246114)[Hotels in Eastern Panama](https://expedia.com/Eastern-Panama-Hotels.d6246114.Travel-Guide-Hotels)[Flights to Eastern Panama](https://expedia.com/Cheap-Flights-To-Eastern-Panama.d6246114.Travel-Guide-Flights)[Car Rentals in Eastern Panama](https://expedia.com/Car-Rentals-In-Eastern-Panama.d6246114.Car-Rental-Guide)[Eastern Panama Vacation Packages](https://expedia.com/Eastern-Panama.d6246114.Destination-Travel-Guides)

![](https://images.trvl-media.com/place/6246376/42fe0cae-c805-47d5-a705-ee119c68d58c.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Nico Barner

![](https://images.trvl-media.com/place/6246376/42fe0cae-c805-47d5-a705-ee119c68d58c.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=6246114&startDate=2026-04-17&endDate=2026-04-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 29 - May 31](https://www.expedia.com/Hotel-Search?regionId=6246114&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Jun 26 - Jun 28](https://www.expedia.com/Hotel-Search?regionId=6246114&startDate=2026-06-26&endDate=2026-06-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jul 24 - Jul 26](https://www.expedia.com/Hotel-Search?regionId=6246114&startDate=2026-07-24&endDate=2026-07-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Eastern Panama vacation rentals

![Boating](https://images.trvl-media.com/lodging/47000000/46960000/46955400/46955399/fad9e47a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Panoramic Cabin](https://images.trvl-media.com/lodging/47000000/46960000/46955400/46955399/b620dae0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Panoramic Cabin | Beach/ocean view](https://images.trvl-media.com/lodging/47000000/46960000/46955400/46955399/8b5aa11c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/47000000/46960000/46955400/46955399/1c15e003.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### San Blas Private Oceanfront Cabin

[](https://www.expedia.com/San-Blas-Private-Oceanfront-Cabin.h46955399.Hotel-Information)

Narganá

$359 nightly

$385 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/San-Blas-Private-Oceanfront-Cabin.h46955399.Hotel-Information)

![Basic Cabin, Ocean View | Beach | On the beach, white sand, free beach shuttle](https://images.trvl-media.com/lodging/125000000/124420000/124417300/124417283/db3e2027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Cabin, Ocean View | View from property](https://images.trvl-media.com/lodging/125000000/124420000/124417300/124417283/428cf4cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Cabin, Ocean View | Exterior](https://images.trvl-media.com/lodging/125000000/124420000/124417300/124417283/a8dab923.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Cabin, Ocean View | Exterior](https://images.trvl-media.com/lodging/125000000/124420000/124417300/124417283/2810954c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sanblastourgy

[](https://www.expedia.com/Nargana-Hotels-Sanblastourgy.h124417283.Hotel-Information)

Nargana

$251 nightly

$276 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/Nargana-Hotels-Sanblastourgy.h124417283.Hotel-Information)

![Basic Cabin, Multiple Beds, Balcony, Sea View | Beach/ocean view](https://images.trvl-media.com/lodging/108000000/107990000/107987100/107987054/5e4a77e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms](https://images.trvl-media.com/lodging/108000000/107990000/107987100/107987054/e1ca9c21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Cabin, Multiple Beds, Balcony, Sea View | Bathroom | Separate tub and shower, toilet paper](https://images.trvl-media.com/lodging/108000000/107990000/107987100/107987054/0c7c55ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms](https://images.trvl-media.com/lodging/108000000/107990000/107987100/107987054/d4916902.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### San Blas Tour Aridub

[](https://www.expedia.com/San-Blas-Tour-Aridub.h107987054.Hotel-Information)

Narganá

$131 nightly

$144 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/San-Blas-Tour-Aridub.h107987054.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/1649bd69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/4fd01df8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/07d64ddb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/073e10ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabaña La Punta op het Strand!!

[](https://www.expedia.com/Cabana-La-Punta-Op-Het-Strand.h103636720.Hotel-Information)

Colón Province

$170 nightly

$170 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/Cabana-La-Punta-Op-Het-Strand.h103636720.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/72000000/71150000/71141100/71141036/803cd264.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/72000000/71150000/71141100/71141036/c41bafb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach](https://images.trvl-media.com/lodging/72000000/71150000/71141100/71141036/1b7d8cbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/72000000/71150000/71141100/71141036/b3c05fe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Catamaran experience in paradise

[](https://www.expedia.com/San-Blas-Islands-Hotels-Catamaran-Experience-In-Paradise.h71141036.Hotel-Information)

Guna Yala Comarca

$917 nightly

$917 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/San-Blas-Islands-Hotels-Catamaran-Experience-In-Paradise.h71141036.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/121000000/120040000/120034500/120034445/0b910251.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/121000000/120040000/120034500/120034445/w1296h891x0y0-1b08f53f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, stovetop, coffee/tea maker, toaster](https://images.trvl-media.com/lodging/121000000/120040000/120034500/120034445/bb4bcbb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/121000000/120040000/120034500/120034445/3d134b58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama

[](https://www.expedia.com/Fabulous-4-Bedroom-Catamaran-In-San-Blas-Panama.h120034445.Hotel-Information)

Guna Yala Comarca

$937 nightly

$937 total

Apr 3 - Apr 4

Total with taxes and fees

[](https://www.expedia.com/Fabulous-4-Bedroom-Catamaran-In-San-Blas-Panama.h120034445.Hotel-Information)

![Beach nearby, beach towels](https://images.trvl-media.com/lodging/114000000/113060000/113058600/113058539/a2a99590.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/114000000/113060000/113058600/113058539/bed98230.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/114000000/113060000/113058600/113058539/da467749.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, oven, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/114000000/113060000/113058600/113058539/07d1058d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Exclusive sailboat for 2 people all inclusive in San Blas islands

[](https://www.expedia.com/Ailigandi-Hotels-Vrbo-Property.h113058539.Hotel-Information)

Guna Yala

10/10

Exceptional

(1 review)

"Anita e Federico sono state il valore aggiunto in queste isole meravigliose. La loro disponibilita, le loro attenzioni, i sorridenti contatti di Anita con la popolazione dei Guna e la cucina superlativa di Federico hanno reso speciale la nostra vacanza che ha soddisfatto appieno le nostre aspettative. Discreta e deliziosa la presenza della gattina (la principessa di bordo) Shanu. Grazie di tutto!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Grazia B.

$606 nightly

$606 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/Ailigandi-Hotels-Vrbo-Property.h113058539.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/34000000/33020000/33018800/33018721/fa337c68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach](https://images.trvl-media.com/lodging/34000000/33020000/33018800/33018721/e6b8f41d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach](https://images.trvl-media.com/lodging/34000000/33020000/33018800/33018721/b2886ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach](https://images.trvl-media.com/lodging/34000000/33020000/33018800/33018721/93d05a41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Private cabin in San Blas

[](https://www.expedia.com/San-Blas-Islands-Hotels-Private-Cabin-In-San-Blas.h33018721.Hotel-Information)

Panama , Betania

$302 nightly

$302 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/San-Blas-Islands-Hotels-Private-Cabin-In-San-Blas.h33018721.Hotel-Information)

![Marina](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/de84a70a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/9f704818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, bed sheets](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/1e44d7b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/a6aae70d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Despierta sobre el mar 

[](https://www.expedia.com/Puerto-Lindo-Hotels-Despierta-Sobre-El-Mar.h108562093.Hotel-Information)

Garrote

6.0/10

(1 review)

$100 nightly

$108 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/Puerto-Lindo-Hotels-Despierta-Sobre-El-Mar.h108562093.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/95ace113.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/66a17c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/14bad027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/551ebe2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Deluxe Beachfront 4-bedroom house in Colón Province

[](https://www.expedia.com/Isla-Grande-Hotels-Deluxe-Beachfront-4-Bedroom-House-In-Colon-Province.h120061071.Hotel-Information)

Colón Province

$382 nightly

$382 total

Apr 6 - Apr 7

Total with taxes and fees

[](https://www.expedia.com/Isla-Grande-Hotels-Deluxe-Beachfront-4-Bedroom-House-In-Colon-Province.h120061071.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/115000000/114700000/114691500/114691452/3d98011b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/115000000/114700000/114691500/114691452/a0ff3f5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/115000000/114700000/114691500/114691452/627278cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114700000/114691500/114691452/7123cf2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Elegance and comfort in old town panama

[](https://www.expedia.com/24-De-Diciembre-Hotels-Elegance-And-Comfort-In-Old-Town-Panama.h114691452.Hotel-Information)

Panamá

$90 nightly

$90 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/24-De-Diciembre-Hotels-Elegance-And-Comfort-In-Old-Town-Panama.h114691452.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/116000000/115840000/115832800/115832785/9bf6774d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/116000000/115840000/115832800/115832785/bde6b74f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/116000000/115840000/115832800/115832785/23785068.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/116000000/115840000/115832800/115832785/ac93b6ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita

[](https://www.expedia.com/Maria-Chiquita-Hotels-Bala-Bliss-Charming-2-Bedroom-Apartment-With-WiFi.h115832785.Hotel-Information)

Maria Chiquita

6.8/10

(3 reviews)

"Well-appointed apartment, view of the ocean, big pool, fast Internet, attentive security. We had a great time here, thanks!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Will

$145 nightly

$145 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/Maria-Chiquita-Hotels-Bala-Bliss-Charming-2-Bedroom-Apartment-With-WiFi.h115832785.Hotel-Information)

![On the beach, sun loungers, beach towels](https://images.trvl-media.com/lodging/75000000/74060000/74054900/74054867/w1064h805x0y11-7ae51d02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books, stereo](https://images.trvl-media.com/lodging/75000000/74060000/74054900/74054867/ad3a9028.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/75000000/74060000/74054900/74054867/1ac172a0_edited_9bc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/75000000/74060000/74054900/74054867/252623d6_edited_e05d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### BEAUTIFUL APARTMENT IN FRONT OF THE SEA

[](https://www.expedia.com/Portobelo-Hotels-BEAUTIFUL-APARTMENT-IN-FRONT-OF-THE-SEA.h74054867.Hotel-Information)

Portobelo

7.0/10

Good

(4 reviews)

"All of it! Gabriel is a marvelous host; absolutely above and beyond. The house is lovely, very unique, and the location, right on the water, superb. We'll be back!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rosa M.

$177 nightly

$177 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/Portobelo-Hotels-BEAUTIFUL-APARTMENT-IN-FRONT-OF-THE-SEA.h74054867.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/46000000/45030000/45022900/45022806/1f45d7b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/46000000/45030000/45022900/45022806/743536b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/46000000/45030000/45022900/45022806/d2331d06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/46000000/45030000/45022900/45022806/810fb7dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Jacuzy, pool and lake at the same house.

[](https://www.expedia.com/Nueva-Providencia-Hotels-Jacuzy.h45022806.Hotel-Information)

Colon

6.0/10

(2 reviews)

"Great. Please take care of the cat"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

KENNETH E.

$69 nightly

$69 total

Apr 13 - Apr 14

Total with taxes and fees

[](https://www.expedia.com/Nueva-Providencia-Hotels-Jacuzy.h45022806.Hotel-Information)

![Room](https://images.trvl-media.com/lodging/114000000/113910000/113907400/113907341/6c8f62cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/114000000/113910000/113907400/113907341/040f3b89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/114000000/113910000/113907400/113907341/506d6189.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/114000000/113910000/113907400/113907341/034ae36a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beautiful 2-bedroom apartment in Cerro Azul for your jungle getaway

[](https://www.expedia.com/24-De-Diciembre-Hotels-Beautiful-2-Bedroom-Apartment-In-Cerro-Azul-For-Your-Jungle-Getaway.h113907341.Hotel-Information)

Panamá

$140 nightly

$140 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/24-De-Diciembre-Hotels-Beautiful-2-Bedroom-Apartment-In-Cerro-Azul-For-Your-Jungle-Getaway.h113907341.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/65000000/64080000/64076800/64076768/4d5df04f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/65000000/64080000/64076800/64076768/04b56517.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/65000000/64080000/64076800/64076768/2c4ad4ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/65000000/64080000/64076800/64076768/d5074a84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Your Menus de la Montaña country house awaits you

[](https://www.expedia.com/Caimitillo-Hotels-Your-Menus-De-La-Montana-Country-House-Awaits-You.h64076768.Hotel-Information)

Panama

$229 nightly

$229 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/Caimitillo-Hotels-Your-Menus-De-La-Montana-Country-House-Awaits-You.h64076768.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/119000000/118960000/118951200/118951165/eefeb662.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast meal](https://images.trvl-media.com/lodging/119000000/118960000/118951200/118951165/23dccb12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/119000000/118960000/118951200/118951165/bc739ca2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/119000000/118960000/118951200/118951165/46b29819.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming cottage with 2 separate beds and a beautiful view of the river

[](https://www.expedia.com/Santa-Rosa-Hotels-Charming-Cottage-With-2-Separate-Beds-And-A-Beautiful-View-Of-The-River.h118951165.Hotel-Information)

Santa Rosa

10/10

Exceptional

(1 review)

"Wir fanden die Unterkunft aufgrund der guten Wegbeschreibung sofort. Die Empfang war sehr nett. Das Haus war sehr sehr sauber und wir haben uns sehr wohl gefühlt. Alles war perfekt. Es war die sauberste/beste Unterkunft die wir bei unserer Panama Rundtour in Panama hatte. Erik und Alba alles Gute und vielen Dank."

![Germany](https://a.travel-assets.com/egds/marks/flags/de.svg)

Birgit U.

$146 nightly

$146 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/Santa-Rosa-Hotels-Charming-Cottage-With-2-Separate-Beds-And-A-Beautiful-View-Of-The-River.h118951165.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/108000000/107130000/107121900/107121885/3c7390e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/108000000/107130000/107121900/107121885/b0a6724c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/108000000/107130000/107121900/107121885/85c634cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/108000000/107130000/107121900/107121885/1918a65d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hacienda La Perezosa in Cerro Azul

[](https://www.expedia.com/24-De-Diciembre-Hotels-Hacienda-La-Perezosa-In-Cerro-Azul.h107121885.Hotel-Information)

Panamá

$971 nightly

$995 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/24-De-Diciembre-Hotels-Hacienda-La-Perezosa-In-Cerro-Azul.h107121885.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/115000000/114230000/114220300/114220227/f538191e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/115000000/114230000/114220300/114220227/bae0d59a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/115000000/114230000/114220300/114220227/e8dc67fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/115000000/114230000/114220300/114220227/5cf47d84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tranquil cabin with WiFi in Los Altos de Cerro Azul

[](https://www.expedia.com/Caimitillo-Hotels-Tranquil-Cabin-With-WiFi-In-Los-Altos-De-Cerro-Azul.h114220227.Hotel-Information)

Los Altos de Cerro Azul

$202 nightly

$202 total

Apr 6 - Apr 7

Total with taxes and fees

[](https://www.expedia.com/Caimitillo-Hotels-Tranquil-Cabin-With-WiFi-In-Los-Altos-De-Cerro-Azul.h114220227.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/84000000/83810000/83809000/83808902/w1080h1080x0y3-cca86cce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/84000000/83810000/83809000/83808902/402c3e62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/84000000/83810000/83809000/83808902/w1080h1080x0y0-90b46174.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/84000000/83810000/83809000/83808902/w1080h1077x0y3-df0c84b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa de Campo / E C O Aventura / Clima 18 a 25

[](https://www.expedia.com/Caimitillo-Hotels-Casa-De-Campo-E-C-O-Aventura-Clima-18-A-25.h83808902.Hotel-Information)

Panamá

2.0/10

(1 review)

$403 nightly

$403 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/Caimitillo-Hotels-Casa-De-Campo-E-C-O-Aventura-Clima-18-A-25.h83808902.Hotel-Information)

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## Find vacation rentals that suit your style

Cabins

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Cottages

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Houseboats

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## Top Eastern Panama Hotel Reviews

![Private Ocean-Front Cabin with private bathroom on San Blas Island](https://images.trvl-media.com/lodging/38000000/37770000/37767000/37766985/a23e7585_y.jpg)

### Private Ocean-Front Cabin with private bathroom on San Blas Island

10/10 Excellent

"Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door. "

[](https://expedia.com/San-Blas-Islands-Hotels-Cabins-In-Diablo-Island.h37766985.Hotel-Information)

![Ordovician Beach Resort](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/9a39b281_y.jpg)

### Ordovician Beach Resort

10/10 Excellent

"The resort was outstanding. It exceeded expectations in every way. The service was the best we had in Panama. The cocktails were fun and the food was delicious and they have a vegan menu. We stayed in a king room and it was very private, pristine and well appointed."

[](https://expedia.com/Ordovician-Beach-Resort.h103761591.Hotel-Information)

![Ranchos de Chalia](https://images.trvl-media.com/lodging/106000000/105450000/105444000/105443903/fedfb071_y.jpg)

### Ranchos de Chalia

10/10 Excellent

"Amazing location, beautiful vistas of mountains, forest and ocean. Very relaxing environment with infinity pool. Well maintained grounds. Wonderful breakfast and dinners. Jose and Anna were amazing hosts. Marijka and Garth"

[](https://expedia.com/Puerto-Lindo-Hotels-Ranchos-De-Chalia.h105443903.Hotel-Information)

![Konsenda San Blas](https://images.trvl-media.com/lodging/100000000/99080000/99079700/99079675/5ba2b554_y.jpg)

### Konsenda San Blas

10/10 Excellent

"Great location for bird watching! The hosts were friendly and helpful. It is best to contact them directly using WhatsApp in addition to booking on Expedia."

[](https://expedia.com/El-Llano-Hotels-Konsenda-San-Blas.h99079675.Hotel-Information)

![Ciel y Miel ](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/272cbe65_y.jpg)

### Ciel y Miel 

10/10 Excellent

"The views from this mountain-top boutique hotel are extraordinary."

[](https://expedia.com/Cacique-Hotels-Ciel-Y-Miel.h96734959.Hotel-Information)

![BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES](https://images.trvl-media.com/lodging/31000000/30800000/30792300/30792236/e39b72a8_y.jpg)

### BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

10/10 Excellent

"This was an incredible stay with so many lovely preparation of meals from Lucy and Jose. They were helpful and so thoughtful. We rested, relaxed, and spent leisurely days being together as a family. If only this happened more often! What a great trip. I am sad it ended so soon. Thank you to a wonderful host, Leticia, who went above and beyond helpful. "

[](https://expedia.com/Palenque-Hotels-Palenque-Spectacular-Caribbean-Ocean-Front-Property-In-Panama.h30792236.Hotel-Information)

## Find out more about Eastern Panama

**Everything you need to know about Eastern Panama vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Eastern Panama vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Eastern Panama vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Eastern Panama vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Eastern Panama. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Eastern Panama in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $144 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Eastern Panama rentals**

At Expedia, we put the best Eastern Panama vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Eastern Panama rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Eastern Panama vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Eastern Panama. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Explore a world of travel with Expedia

- Trending destinations on Expedia.com
- All accommodation types in Eastern Panama

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- [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations)

- [Vacation Homes in Eastern Panama ](https://expedia.com/Eastern-Panama-Private-Vacation-Homes.d6246114-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Apartments in Eastern Panama ](https://expedia.com/Eastern-Panama-Apartments.d6246114-aaApartments.Travel-Guide-Accommodation)
- [Houseboats in Eastern Panama ](https://expedia.com/Eastern-Panama-Houseboats.d6246114-aaHouseboats.Travel-Guide-Accommodation)
- [Cabin Rentals in Eastern Panama ](https://expedia.com/Eastern-Panama-Cabins.d6246114-aaCabins.Travel-Guide-Accommodation)
- [Lodges in Eastern Panama ](https://expedia.com/Eastern-Panama-Lodges.d6246114-aaLodges.Travel-Guide-Accommodation)
- [Villas in Eastern Panama ](https://expedia.com/Eastern-Panama-Villas.d6246114-aaVillas.Travel-Guide-Accommodation)
- [B&B in Eastern Panama ](https://expedia.com/Eastern-Panama-Bed-And-Breakfast.d6246114-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Cottages in Eastern Panama ](https://expedia.com/Eastern-Panama-Cottages.d6246114-aaCottages.Travel-Guide-Accommodation)
- [Hostels in Eastern Panama ](https://expedia.com/Eastern-Panama-Hostels.d6246114-aaHostels.Travel-Guide-Accommodation)
- [Condo Rentals in Eastern Panama ](https://expedia.com/Eastern-Panama-Condos.d6246114-aaCondos.Travel-Guide-Accommodation)
- [RV Parks in Eastern Panama ](https://expedia.com/Eastern-Panama-RV-Parks.d6246114-aaRVParks.Travel-Guide-Accommodation)
- [Farmstay in Eastern Panama ](https://expedia.com/Eastern-Panama-Agritourism.d6246114-aaAgritourism.Travel-Guide-Accommodation)
- [Resorts in Eastern Panama ](https://expedia.com/Eastern-Panama-Resorts.d6246114-aaResorts.Travel-Guide-Accommodation)
- [Guest Houses in Eastern Panama ](https://expedia.com/Eastern-Panama-Guest-Houses.d6246114-aaGuestHouses.Travel-Guide-Accommodation)

### Expedia's Latest Trends

Hotels

- [Hotels in Panama City](https://expedia.com/Panama-City-Hotels.d2897.Travel-Guide-Hotels)
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- [All-inclusive Resorts in Panama Canal Zone](https://expedia.com/Panama-Canal-Zone-Hotels-All-Inclusive-Hotel.0-0-d6222968-tAllinclusiveHotel.Travel-Guide-Filter-Hotels)
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- [Hotels in Boquete](https://expedia.com/Boquete-Hotels.d500194.Travel-Guide-Hotels)
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Cars

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Vacation Rentals

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General

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- [Visit Panama City](https://expedia.com/Panama-City.dx2897)

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