Eastern Panama

Travel Guide

50 Shades of blue. Sailing through the San Blas Islands in Panama lets you experience a pure paradise and crystal clear water. You can buy fresh fish and other seefood drirectly from local fishermen. If you want you can also play Robinson Crusoe on islands with literally only one palm tree. #BVSBlue
50 Shades of blue. Sailing through the San Blas Islands in Panama lets you experience a pure paradise and crystal clear water. You can buy fresh fish and other seefood drirectly from local fishermen. If you want you can also play Robinson Crusoe on islands with literally only one palm tree. #BVSBlue
A Kuna Yala man headed out to fish. If you have ever dreamed of spending a night or two on a small, private island, check out Kuna Yala. If you don't like roughing it a little bit, this might not be for you. There are cabins with flushing toilets but no electricity and the shower water is rather cool. Great place to get away from crowds and unplug though. #islands #peaceful #Adventure #water #ocean #boat #trovember
A definite bucketlist place to visit if ever in #Panama. #SanBlas
Secluded island in the Guna Yala region of Panama
HOTEL ISLA GRANDE

HOTEL ISLA GRANDE

3 out of 5
Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province
$92 nightly
The price is $102 total per night from Jan 31 to Feb 1
$102 total
Jan 31 - Feb 1
Total with taxes and fees
Book a stay at this beach hotel in Isla Grande. Enjoy free breakfast, a beach locale, and onsite spa services. Popular attractions Isla Mamey and Portobelo National ...
4.8/10 (5 reviews)
Although I gave this hotel a medium rating I enjoyed myself. This is a rough almost close to camping hotel. I must have not seen the message about bringing soap wash clothes, hand towel, tissue actually everything. The water does not get cold and there was a party set up just outside the window lasting ...

Reviewed on Sep 19, 2025

HOTEL ISLA GRANDE
Ranchos de Chalia

Ranchos de Chalia

3 out of 5
Portobelo via Puerto Lindo, Unit 3 Puerto Lindo Colón
$117 nightly
The price is $129 total per night from Jan 25 to Jan 26
$129 total
Jan 25 - Jan 26
Total with taxes and fees
Stay at this hotel in Puerto Lindo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located ...
9.6/10 Exceptional! (13 reviews)
Beautiful tranquility in nature, amazing staff

Reviewed on Nov 23, 2025

Ranchos de Chalia
Konsenda San Blas

Konsenda San Blas

2 out of 5
Llano Cartí Km 11 El Llano Panamá Province
Stay at this hotel in El Llano. Enjoy free breakfast, free parking, and a garden.
10/10 Exceptional! (1 review)
wonderful eco lodge in the forest. Easy to reach by car, just on the main road. Paths to walk, excellent meals. A very good option if you need to relax before and after visiting Sab Blas, but worth the trip on its own, beautiful landscape.

Reviewed on Mar 6, 2025

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Konsenda San Blas
See all 177 properties in Eastern Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Private Over the Water Cabin on San Blas Island

Private Over the Water Cabin on San Blas Island

2 out of 5
9.542876, -78.899058 Narganá San Blas
Book a stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Chichime ...
7/10 Good! (6 reviews)
Very nice. And I liked the food

Reviewed on Aug 14, 2025

Private Over the Water Cabin on San Blas Island
San Blas Private Beach Cabin

San Blas Private Beach Cabin

2.5 out of 5
Nusatupo Narganá Guna Yala
Book a stay at this beach cabin in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Museum of the Kuna ...
San Blas Private Beach Cabin
Caribbean getaway: beach cottage just on the sand

Caribbean getaway: beach cottage just on the sand

Palenque Provincia de Colón
Book a stay at this beach cottage in Palenque. Enjoy free WiFi, a beach locale, and a garden.
10/10 Exceptional! (1 review)
The beach view was perfect! I loved hearing the waves all day and throughout the night. My dog and I enjoyed everything and felt very comfortable.

Reviewed on Oct 15, 2025

Caribbean getaway: beach cottage just on the sand
See all properties in Eastern Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Secluded island in the Guna Yala region of Panama

Isla Diablo

Commune with nature and explore the great outdoors at Isla Diablo during your travels in San Blas Islands. Take in the festivals while you're in the area.

Isla Diablo

Isla Chichime

Commune with nature and explore the great outdoors at Isla Chichime during your travels in San Blas Islands. Take in the festivals while you're in the area.

Isla Chichime

Museum of the Kuna Nation

You can spend an afternoon studying the exhibits at Museum of the Kuna Nation in Narganá. Stroll along the seaside or experience the area's festivals.

Museum of the Kuna Nation

Cities near Eastern Panama

Islands of San Blas , Panama; Shutterstock ID 687617053; Purchase Order: -

San Blas Islands

Palm trees forest and houses in Isla Grande shore. Colon province, Panama, Caribbean, Central America.

Isla Grande

#lifeatexpedia Beautiful Portobelo is full of history and culture. Located on the Caribbean coast it has a variety of world class attractions. The historic town of Portobelo is one of the most scenic spots in Panama. Set on a turquoise Caribbean bay, it was Spanish Empires' s trade epicenter in the 16th and 17th century. Don´t miss the Portobello Fortress and the Cristo Negro Church!

Portobelo

A beautiful national park.

Caimitillo