Greater Antilles Vacations from $334

Book a Hotel + Flight or Car together to unlock savings

Photo by Hande Gokoglu
  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Greater Antilles Vacation

Open yourself to new adventures with a Greater Antilles vacation package. History and culture will be just a couple of the many highlights of your getaway. Start your trip to Greater Antilles by spending some time in Punta Cana, one of the best cities here. Expedia is a one-stop shop for organizing your Greater Antilles vacation. From accommodations and flights, to car rentals and activities, we're here to help you create a travel experience like no other.

The Latest Greater Antilles vacation packages

Price found within the past 48 hours. Click for updated prices.
Westgate Las Vegas Resort & Casino
Creekside Inn
The LINQ Hotel & Casino – A Caesars Rewards Destination
Virgin Hotel Las Vegas, Curio Collection by Hilton
Casablanca Miami Beach
Don't see what you're looking for?
See all available trips from Columbus to Greater Antilles
View all trips

Discover the most popular places to visit in Greater Antilles

Greater Antilles Hotel Deals

Hotel Riu Republica - Adults only - All Inclusive

Hotel Riu Republica - Adults only - All Inclusive

4 out of 5
Playa Arena Gorda Punta Cana
7.2/10 Good! (5,542 reviews)
Everyone was friendly happy people good service, I didn’t even wanted to come back home 😊👌 lovely place I will recommend this service 💯,

Reviewed on Mar 17, 2026

Hotel Riu Republica - Adults only - All Inclusive
Hotel Riu Montego Bay - Adults Only - All Inclusive

Hotel Riu Montego Bay - Adults Only - All Inclusive

4 out of 5
Mahoe Bay, Ironshore Montego Bay Saint James
8.6/10 Excellent! (5,167 reviews)
This hotel was everything my husband and I were very pleased. The food was delicious and the activities were fun. Overall the best trip I’ve ever had. Will visit again in a couple of months.

Reviewed on Mar 17, 2026

Hotel Riu Montego Bay - Adults Only - All Inclusive
Serenade Punta Cana Beach & Spa Resort - All Inclusive

Serenade Punta Cana Beach & Spa Resort - All Inclusive

4.5 out of 5
Carretera Cabeza de Toro Punta Cana La Altagracia
$291 nightly
The price is $373 total per night from Apr 12 to Apr 13
$373 total
Apr 12 - Apr 13
Total with taxes and fees
8/10 Very Good! (6,715 reviews)
We got “upgraded” to a pool room, which was nice but we did not ask for it and it ended up being an accessible room which I’m sure people that needed it would have appreciated but it made things harder for us (I’m aware how this sounds). Room was clean, but a little outdated. The bathroom had definitely ...

Reviewed on Mar 17, 2026

Serenade Punta Cana Beach & Spa Resort - All Inclusive
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Greater Antilles Vacation Packages

More vacations you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.