When you've finished at this Downtown Chicago display of scientific achievements, why not make your way to Wrigley Field, Millennium Park, and Willis Tower? They're near International Museum of Surgical Science and also popular with many tourists.

Plan a trip to see International Museum of Surgical Science

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The Allegro Royal Sonesta Hotel Chicago Loop

Downtown Chicago

$468

per person

Nov 10 - Nov 16

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Chicago (ORD)

9/10 Wonderful! (2,027 reviews)

Amazing hotel. Great location.

Reviewed on Sep 28, 2025

Hotel Riu Plaza Chicago

Downtown Chicago

Save 100% on your flight

$609

per person

Nov 10 - Nov 16

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Chicago (ORD)

9.4/10 Exceptional! (2,427 reviews)

Great place to stay. Clean and quiet and conveniently located to all types of eating, shopping, and river walk. Great breakfast buffet to start the day and fantastic rooftop bar for the evening!

Reviewed on Sep 28, 2025

The Emily Hotel

Downtown Chicago

Save 100% on your flight

$738

per person

Oct 31 - Nov 5

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Chicago (ORD)

9.2/10 Wonderful! (1,222 reviews)

Beautiful hotel in great walkable area. There were major renovations going on while we were there so our actual floor was a bit messy/busy, although the common areas remained lovely. Would stay again for the good location. All staff very nice.

Reviewed on Sep 29, 2025

Browse tours and tickets to explore International Museum of Surgical Science

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Eastside Chicago The Heist Exploration Game and Tour

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360 CHICAGO Observation Deck

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Chicago Bulls Basketball Game at United Center

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