Keeners Vacations from $363

Book a Hotel + Flight or Car together to unlock savings

Plan, book, travel with confidence
Better together
Save up to $2,000 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

The Latest Keeners vacation packages

Price found within the past 48 hours. Click for updated prices.

Drury Inn & Suites Cape Girardeau

$363

per person

Oct 1 - Oct 4

found 5 hours ago

Roundtrip flight included

Chicago (ORD) to Cape Girardeau (CGI)

9.4/10 Exceptional! (1,005 reviews)

Everything was awesome, highly recommended this hotel

Reviewed on Aug 7, 2026

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

$401

per person

Oct 1 - Oct 4

found 1 day ago

Roundtrip flight included

Chicago (ORD) to Cape Girardeau (CGI)

9.4/10 Exceptional! (1,004 reviews)

Very nice hotel and staff. Would definitely recommend

Reviewed on Aug 9, 2026

EC Reed's Mercantile and Hotel

$842

per person

Sep 21 - Sep 23

found 3 hours ago

Roundtrip non-stop flight included

Monroe (MLU) to Cape Girardeau (CGI)

9.4/10 Exceptional! (105 reviews)

Drury Inn & Suites Jackson MO

$393

per person

Oct 1 - Oct 4

found 5 hours ago

Roundtrip flight included

Chicago (ORD) to Cape Girardeau (CGI)

9.6/10 Exceptional! (1,004 reviews)

Very clean. Amenities good. Staff helpful and kind.

Reviewed on Aug 12, 2026

University Inn of Carbondale by Hotel O

$794

per person

Sep 14 - Sep 16

found 1 day ago

Roundtrip non-stop flight included

Monroe (MLU) to Cape Girardeau (CGI)

5.8/10 (401 reviews)

it was being constructed!

Reviewed on Aug 11, 2026

Don't see what you're looking for?

See all available trips from Columbus to Keeners

View all trips

Keeners Hotel Deals

Motel 6 Poplar Bluff, MO

4101 Highway 67 N Poplar Bluff MO

Fully refundableReserve now, pay when you stay

$72 nightly

$81 total

Aug 14 - Aug 15

Total with taxes and fees

Fairfield Inn & Suites by Marriott Poplar Bluff

3109 Oak Grove Poplar Bluff MO

Fully refundableReserve now, pay when you stay

$101 nightly

$114 total

Aug 23 - Aug 24

Total with taxes and fees

Drury Inn & Suites Poplar Bluff

2220 N Westwood Blvd Poplar Bluff MO

Fully refundableReserve now, pay when you stay

$94 nightly

$106 total

Aug 20 - Aug 21

Total with taxes and fees

9.4/10 Exceptional! (1,011 reviews)

"Excellent free dinner and hot breakfast. Indoor and outdoor pool. Terrific staff."

Reviewed on Aug 10, 2026

See all 52 properties in Keeners

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.