Midtown East Vacations from $606

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Your Midtown East Vacation

Discover everything that Midtown East has to offer with a tailor-made Midtown East vacation package. From its shopping and cafes to its nightlife, get ready to fall for the charms of this busy neighborhood. Not sure where to go during your trip to Midtown East? Nearby attractions such as Times Square, Broadway and Rockefeller Center are excellent places to start. Stop daydreaming and start doing. When it's time to book your next vacation to Midtown East, Expedia will help get you there.

The Latest Midtown East Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Park Lane New York
1 Hotel Central Park
The William Vale
The Towers at Lotte New York Palace
WestHouse New York

Where to stay in Midtown East

Find the best Midtown East areas and neighborhoods for the activities you enjoy most. Learn more about Midtown East

Midtown East Hotel Deals

Hyatt Grand Central New York

Hyatt Grand Central New York

4 out of 5
109 East 42nd Street New York NY
Fully refundableReserve now, pay when you stay
$209 nightly
The price is $243 total per night from Mar 29 to Mar 30
$243 total
Mar 29 - Mar 30
Total with taxes and fees
8.2/10 Very Good! (6,512 reviews)
Great location, just besides grand central , give you access to the whole city

Reviewed on Mar 10, 2026

Hyatt Grand Central New York
Lotte New York Palace

Lotte New York Palace

4.5 out of 5
455 Madison Ave New York NY
$520 nightly
The price is $600 total per night from Mar 27 to Mar 28
$600 total
Mar 27 - Mar 28
Total with taxes and fees
9/10 Wonderful! (1,951 reviews)
Very good for new York staff is new York so patience is limited lol

Reviewed on Mar 9, 2026

Lotte New York Palace
The Lexington Hotel, Autograph Collection

The Lexington Hotel, Autograph Collection

4 out of 5
511 Lexington Ave at 48th St. New York NY
$192 nightly
The price is $224 total per night from Mar 20 to Mar 21
$224 total
Mar 20 - Mar 21
Total with taxes and fees
8.2/10 Very Good! (1,783 reviews)
I was disappointed with my stay. For a 4-star hotel, the room was very run down—peeling mirror and wallpaper, a stain on the bedspread. There was also construction outside the hotel that continued past midnight. I booked a king room but received a room with two double beds. I couldn’t reach the front ...

Reviewed on Mar 12, 2026

The Lexington Hotel, Autograph Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.