Midtown East Vacations from $502

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Your Midtown East Vacation

Discover everything that Midtown East has to offer with a tailor-made Midtown East vacation package. From its shopping and cafes to its nightlife, get ready to fall for the charms of this busy neighborhood. Not sure where to go during your trip to Midtown East? Nearby attractions such as Times Square, Broadway and Rockefeller Center are excellent places to start. Stop daydreaming and start doing. When it's time to book your next vacation to Midtown East, Expedia will help get you there.

The Latest Midtown East Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Park Lane New York
Hotel Riu Plaza New York Times Square
Hotel Riu Plaza Manhattan Times Square
1 Hotel Brooklyn Bridge
The Towers at Lotte New York Palace

Where to stay in Midtown East

Find the best Midtown East areas and neighborhoods for the activities you enjoy most. Learn more about Midtown East

Midtown East Hotel Deals

Hyatt Grand Central New York

Hyatt Grand Central New York

4 out of 5
109 East 42nd Street New York NY
Fully refundableReserve now, pay when you stay
$253 nightly
The price is $294 total per night from Apr 19 to Apr 20
$294 total
Apr 19 - Apr 20
Total with taxes and fees
8.2/10 Very Good! (6,547 reviews)
Very clean and convenient location to many things!

Reviewed on Mar 22, 2026

Hyatt Grand Central New York
Lotte New York Palace

Lotte New York Palace

4.5 out of 5
455 Madison Ave New York NY
Fully refundableReserve now, pay when you stay
$550 nightly
The price is $635 total per night from Mar 27 to Mar 28
$635 total
Mar 27 - Mar 28
Total with taxes and fees
9/10 Wonderful! (1,958 reviews)
A lovely, iconic property in a great location for restaurants, theater, sightseeing. Hotel was in the process of starting a new reservation system, was seriously unprepared for it, and significantly understaffed causing delays at check in that were incredibly long. It took us 2 visits to the front ...

Reviewed on Mar 21, 2026

Lotte New York Palace
The Lexington Hotel, Autograph Collection

The Lexington Hotel, Autograph Collection

4 out of 5
511 Lexington Ave at 48th St. New York NY
Fully refundableReserve now, pay when you stay
$192 nightly
The price is $224 total per night from Mar 27 to Mar 28
$224 total
Mar 27 - Mar 28
Total with taxes and fees
8.2/10 Very Good! (1,816 reviews)
The front desk staff was helpful Let us check in early The room smelled of mold and the sink was slow to drain i will not be returning to this hotel

Reviewed on Mar 22, 2026

The Lexington Hotel, Autograph Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.