Midtown East Vacations from $395

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Midtown East Vacation

Discover everything that Midtown East has to offer with a tailor-made Midtown East vacation package. From its shopping and cafes to its nightlife, get ready to fall for the charms of this busy neighborhood. Not sure where to go during your trip to Midtown East? Nearby attractions such as Times Square, Broadway and Rockefeller Center are excellent places to start. Stop daydreaming and start doing. When it's time to book your next vacation to Midtown East, Expedia will help get you there.

The Latest Midtown East Vacation Packages

Price found within the past 48 hours. Click for updated prices.
DoubleTree by Hilton Hotel Newark Airport
PUBLIC, an Ian Schrager hotel
1 Hotel Central Park
San Carlos Hotel
Hotel Park Ave NYC

Where to stay in Midtown East

Find the best Midtown East areas and neighborhoods for the activities you enjoy most. Learn more about Midtown East

Midtown East Hotel Deals

Hyatt Grand Central New York

Hyatt Grand Central New York

4 out of 5
109 East 42nd Street New York NY
Fully refundableReserve now, pay when you stay
$226 nightly
The price is $263 total per night from Apr 12 to Apr 13
$263 total
Apr 12 - Apr 13
Total with taxes and fees
8.2/10 Very Good! (6,560 reviews)
Buffet was overpriced, not enough variety of food, need better customer service

Reviewed on Apr 2, 2026

Hyatt Grand Central New York
Lotte New York Palace

Lotte New York Palace

4.5 out of 5
455 Madison Ave New York NY
Fully refundableReserve now, pay when you stay
$522 nightly
The price is $603 total per night from Apr 4 to Apr 5
$603 total
Apr 4 - Apr 5
Total with taxes and fees
9/10 Wonderful! (1,975 reviews)
Just a classic NYC experience with attentive staff, a bar from a century ago. Will stay there again.

Reviewed on Apr 2, 2026

Lotte New York Palace
The Lexington Hotel, Autograph Collection

The Lexington Hotel, Autograph Collection

4 out of 5
511 Lexington Ave at 48th St. New York NY
Fully refundableReserve now, pay when you stay
$207 nightly
The price is $241 total per night from Apr 11 to Apr 12
$241 total
Apr 11 - Apr 12
Total with taxes and fees
8.4/10 Very Good! (1,864 reviews)
Friendly staff, clean room and daily housekeeping. Comfortable bed. Air con. I would have liked a kettle but that’s a personal preference and not a big issue. The hotel was very central. It was walking distance to the Rockefeller Centre, Grand Central Station, 5th Avenue, Broadway, Empire State Building, ...

Reviewed on Apr 2, 2026

The Lexington Hotel, Autograph Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Midtown East

Things to do

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.