Midtown East Vacations from $452

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Your Midtown East Vacation

Discover everything that Midtown East has to offer with a tailor-made Midtown East vacation package. From its shopping and cafes to its nightlife, get ready to fall for the charms of this busy neighborhood. Not sure where to go during your trip to Midtown East? Nearby attractions such as Times Square, Broadway and Rockefeller Center are excellent places to start. Stop daydreaming and start doing. When it's time to book your next vacation to Midtown East, Expedia will help get you there.

The Latest Midtown East Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Newark Liberty International Airport Marriott
Topping Rose House
Hotel St. James
The Ridge Hotel
The Inn At Fox Hollow Hotel

Where to stay in Midtown East

Find the best Midtown East areas and neighborhoods for the activities you enjoy most. Learn more about Midtown East

Midtown East Hotel Deals

Hyatt Grand Central New York

Hyatt Grand Central New York

4 out of 5
109 East 42nd Street New York NY
Fully refundableReserve now, pay when you stay
$226 nightly
The price is $263 total per night from Apr 12 to Apr 13
$263 total
Apr 12 - Apr 13
Total with taxes and fees
8.2/10 Very Good! (6,590 reviews)
Good location but no frills. No coffee or kettle in the room. Very small bathroom with shelf hanging over the sink that made it difficult to wash up. Charged $4/bag to hold them for a few hours after checkout. $15 credit at the market was a nice perk though.

Reviewed on Apr 5, 2026

Hyatt Grand Central New York
Lotte New York Palace

Lotte New York Palace

4.5 out of 5
455 Madison Ave New York NY
Fully refundableReserve now, pay when you stay
$564 nightly
The price is $651 total per night from May 2 to May 3
$651 total
May 2 - May 3
Total with taxes and fees
9/10 Wonderful! (1,981 reviews)
Very well-appointed hotel and room, excellent location, pleasant staff. However, the check-in was too slow for a property of this quality. Also, the property texted me and asked if I needed anything, and I requested a mini fridge. The reply was that it would be delivered to my room, but it never ...

Reviewed on Apr 5, 2026

Lotte New York Palace
The Lexington Hotel, Autograph Collection

The Lexington Hotel, Autograph Collection

4 out of 5
511 Lexington Ave at 48th St. New York NY
Fully refundableReserve now, pay when you stay
$207 nightly
The price is $241 total per night from Apr 12 to Apr 13
$241 total
Apr 12 - Apr 13
Total with taxes and fees
8.4/10 Very Good! (1,874 reviews)
No slippers, no toothbrush, no fridge

Reviewed on Apr 5, 2026

The Lexington Hotel, Autograph Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.