Satisfy the culture vulture within at Movie Museum. Check if there are any guided tours or ask museum staff to direct you to a few collection highlights.
You'll have no end of sightseeing choices when staying in Amsterdam South. Movie Museum is a good place to start here, but there are lots of other worthwhile sights to enjoy. Anne Frank House, Van Gogh Museum, and Dam Square are close to the museum and will round out your day nicely.