Find hotels in Murex Lakes, Sanibel

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Discover Murex Lakes hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

On the beach, white sand, kayaking, motor boating
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4.0 star property
6.8 mi from Murex Lakes
8.4 out of 10, Very Good, (1002)
"This was thr best place that we have ever stayed at. "
United States
Matthew
$231 nightly
The price is $258
Dec 14 - Dec 15
Total with taxes and fees
Marriott Sanibel Harbour Resort & Spa
Interior entrance
Allure Suites

Allure Suites

3.0 star property
14.7 mi from Murex Lakes
7.6 out of 10, Good, (1000)
"Liked the friendly and fast check-in, spacious and clean suite, great location close to stores, soundproof rooms, greetings when I returned each day and reasonable room rates. I would stay again. "
United States
Charles
$71 nightly
The price is $79
Dec 7 - Dec 8
Total with taxes and fees
Allure Suites
Outdoor pool
Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel

3.0 star property
8.8 mi from Murex Lakes
8.6 out of 10, Excellent, (1001)
"Clean room, wonderful staff, and nice breakfast. "
United States
Danielle
$95 nightly
The price is $106
Dec 14 - Dec 15
Total with taxes and fees
Residence Inn by Marriott Fort Myers Sanibel
Property amenity
TownePlace Suites by Marriott Fort Myers Estero

TownePlace Suites by Marriott Fort Myers Estero

3.5 star property
18.4 mi from Murex Lakes
9.4 out of 10, Exceptional, (457)
"Perfect Stay!"
Brazil
Bruno
$125 nightly
The price is $139
Dec 14 - Dec 15
Total with taxes and fees
TownePlace Suites by Marriott Fort Myers Estero
Deluxe Studio, 1 King Bed, Marina View | View from room
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

2.5 star property
9.7 mi from Murex Lakes
8.8 out of 10, Excellent, (1002)
"Great Place to Stay!"
United States
JUDY
$107 nightly
The price is $119
Dec 9 - Dec 10
Total with taxes and fees
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Outdoor pool
Days Inn by Wyndham Fort Myers Springs Resort

Days Inn by Wyndham Fort Myers Springs Resort

2.5 star property
16.6 mi from Murex Lakes
6.0 out of 10, (1000)
"It was a really clean hotel "
United States
Tina
$67 nightly
The price is $75
Dec 7 - Dec 8
Total with taxes and fees
Days Inn by Wyndham Fort Myers Springs Resort
Exercise/lap pool
Hyatt Vacation Club at Coconut Cove, Bonita Springs

Hyatt Vacation Club at Coconut Cove, Bonita Springs

4.0 star property
16.3 mi from Murex Lakes
9.2 out of 10, Wonderful, (719)
"Very pleasant staff, helpful, property well maintained. Great vacation spot with activities for the whole family. "
United States
Mutessa
$199 nightly
The price is $222
Dec 14 - Dec 15
Total with taxes and fees
Hyatt Vacation Club at Coconut Cove, Bonita Springs
Exterior
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

3.0 star property
9.1 mi from Murex Lakes
8.0 out of 10, Very Good, (1004)
"Room was clean and neat, very friendly staff."
United States
Olha
$101 nightly
The price is $113
Dec 21 - Dec 22
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
View from room
Matlacha on Shoreview

Matlacha on Shoreview

2.0 star property
14.4 mi from Murex Lakes
9.6 out of 10, Exceptional, (207)
"Staff was very helpful throughout our stay, defnitley be back. Beautiful view, awesome area, very clean room."
United States
Randy
$105 nightly
The price is $117
Dec 15 - Dec 16
Total with taxes and fees
Matlacha on Shoreview
Exterior
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

2.5 star property
10.9 mi from Murex Lakes
9.4 out of 10, Exceptional, (1000)
"Excellent room and price! Breakfast was great. Holiday Inn Express is doing everything right for a comfortable stay."
United States
Denise
$97 nightly
The price is $108
Dec 14 - Dec 15
Total with taxes and fees
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
Exterior
Latitude 26 Waterfront Boutique Resort - Bonita Springs

Latitude 26 Waterfront Boutique Resort - Bonita Springs

3.0 star property
18.1 mi from Murex Lakes
8.8 out of 10, Excellent, (694)
"We enjoyed our stay. The accommodations were great!"
United States
Conny
$102 nightly
The price is $113
Dec 7 - Dec 8
Total with taxes and fees
Latitude 26 Waterfront Boutique Resort - Bonita Springs
Aerial view
DiamondHead Beach Resort

DiamondHead Beach Resort

3.5 star property
9.6 mi from Murex Lakes
9.0 out of 10, Wonderful, (1001)
"Everything about this resort is spectacular! Staff, amenities, room! We had a wonderful stay!"
United States
Minda
$217 nightly
The price is $243
Dec 7 - Dec 8
Total with taxes and fees
DiamondHead Beach Resort
4 outdoor pools
Hyatt Regency Coconut Point Resort & Spa

Hyatt Regency Coconut Point Resort & Spa

4.5 star property
16.5 mi from Murex Lakes
9.0 out of 10, Wonderful, (1000)
"Very good hotel. Clean, the attention is amazing and many activities to do. The restaurants are excellent. I will definitely recommend it. "
United States
Mariuska
$344 nightly
The price is $384
Dec 14 - Dec 15
Total with taxes and fees
Hyatt Regency Coconut Point Resort & Spa
Exterior
Candlewood Suites Fort Myers Sanibel Gateway by IHG

Candlewood Suites Fort Myers Sanibel Gateway by IHG

3.0 star property
12.4 mi from Murex Lakes
7.4 out of 10, Good, (1002)
"Great place to stay."
United States
David
$87 nightly
The price is $97
Dec 11 - Dec 12
Total with taxes and fees
Candlewood Suites Fort Myers Sanibel Gateway by IHG
Terrace/patio
Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers

3.0 star property
15.9 mi from Murex Lakes
8.6 out of 10, Excellent, (1026)
"Enjoyed our stay, would definitely choose the Hilton Garden Inn for future stays"
United States
Barbara
$104 nightly
The price is $116
Dec 14 - Dec 15
Total with taxes and fees
Hilton Garden Inn Ft Myers
Free buffet breakfast
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

2.5 star property
13.2 mi from Murex Lakes
9.4 out of 10, Exceptional, (1016)
"Comfy bed, clean room, good breakfast "
United States
Darwin
$95 nightly
The price is $106
Dec 7 - Dec 8
Total with taxes and fees
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Suite with King Bed, Beachfront, Balcony | Terrace/patio
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 star property
9.3 mi from Murex Lakes
9.0 out of 10, Wonderful, (1006)
"Clean rooms, friendly staff, so much to do there and nearby "
United States
Lisa R
$154 nightly
The price is $172
Dec 7 - Dec 8
Total with taxes and fees
Lani Kai Beachfront Resort
Pillowtop beds, desk, iron/ironing board, free cribs/infant beds
Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 star property
17.8 mi from Murex Lakes
6.6 out of 10, (1000)
"Location was great"
United States
Jake
$63 nightly
The price is $70
Dec 31 - Jan 1, 2026
Total with taxes and fees
Baymont by Wyndham Fort Myers Central
Outdoor pool, open 7:00 AM to 6:00 PM, pool umbrellas, sun loungers
Hyatt Place Fort Myers Estero

Hyatt Place Fort Myers Estero

3.5 star property
18.1 mi from Murex Lakes
8.8 out of 10, Excellent, (1001)
"Clean rooms freshly remodel staff very friendly breakfast bar was good as well and there a pet friendly hotel wich made my stay awesome with my fur baby and wife"
United States
Jose
$118 nightly
The price is $131
Dec 15 - Dec 16
Total with taxes and fees
Hyatt Place Fort Myers Estero
Outdoor pool, open 8:00 AM to 10:00 PM, cabanas (surcharge)
The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village

4.0 star property
9.8 mi from Murex Lakes
9.0 out of 10, Wonderful, (1000)
"Excellent stay over Thanksgiving holiday!"
United States
Nicole
$180 nightly
The price is $201
Dec 21 - Dec 22
Total with taxes and fees
The Westin Cape Coral Resort At Marina Village
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Murex Lakes

Find the best Murex Lakes areas and neighborhoods for the activities you enjoy most.
Fort Myers featuring a sandy beach
Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography
Open Photo by Sanibel Captiva Chamber of Commerce/Milissa Sprecher Photography

West End

While visiting West End, you might make a stop by sights like J. N. Ding Darling National Wildlife Refuge and Bowman's Beach.

Sanibel Historical Museum and Village showing heritage elements

Mid Island

While visiting Mid Island, you might make a stop by sights like Periwinkle Way and Sanibel Island Southern Beach.

J. N. Ding Darling National Wildlife Refuge which includes marine life and dangerous animals

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Periwinkle Way featuring cycling as well as an individual femail

Beachview Country Club Estates

If you're spending some time in Beachview Country Club Estates, Periwinkle Way and Sanibel Island Golf Club are top sights worth seeing.

Sanctuary

While Sanctuary might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Blind Pass Beach and Turner Beach.

Top Murex Lakes Hotel Reviews

Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops

10/10 Excellent
"A perfect place to rest ! ❤️"
Arely 1-night trip
Posted 1 day ago
Doubletree by Hilton Fort Myers at Bell Tower Shops

Frequently asked questions

Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Murex Lakes.
How can I save on a Murex Lakes hotel booking with Expedia?
One Key™ - Expedia's free travel rewards program - gives you instant access to perks and Member Prices on Murex Lakes hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings.

*OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Murex Lakes hotel?
Hotel prices in Murex Lakes often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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