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Osco Vacation Rentals

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Check prices for these dates

In two weeks
Oct 30 - Nov 1
In two months
Dec 11 - Dec 13
In three months
Jan 8 - Jan 10
In four months
Feb 5 - Feb 7

Our top choices for Osco vacation rentals

A living room with a sofa, armchair, and coffee table. There is a dining area with a table and chairs. A kitchen is visible in the background.

1. Lucy’s House Single Family Bungalow

Lucy’s House Single Family Bungalow
Moline
9.8 out of 10, Exceptional, (106 reviews)
"Easy check in, great price, and all the awesome snacks were a definite perk! Thanks for the great stay."
United States
Elijah
$130 nightly
The price is $138
Oct 18 - Oct 19
Total with taxes and fees
Lucy’s House Single Family Bungalow
A wooden deck with a white railing, overlooking a body of water and a house with a balcony.

2. Riverfront Cabin:Wrap Around Deck & 3 Season Room

Riverfront Cabin:Wrap Around Deck & 3 Season Room
Moline
9.4 out of 10, Exceptional, (34 reviews)
"Great place for a weekend getaway! "
United States
matt l.
$243 nightly
The price is $268
Oct 19 - Oct 20
Total with taxes and fees
Riverfront Cabin:Wrap Around Deck & 3 Season Room
A room with a yellow sofa, a patterned lamp, a green and white abstract curtain, and wall-mounted shelves with plants.

3. River Nest • Waterfront Sunsets + Firepit

River Nest • Waterfront Sunsets + Firepit
South Moline Township
$228 nightly
The price is $229
Nov 1 - Nov 2
Total with taxes and fees
River Nest • Waterfront Sunsets + Firepit
A covered deck with a round table and chairs, overlooking a body of water with an American flag.

4. Island House On Mississippi River

Island House On Mississippi River
East Moline
8.2 out of 10, Very good, (46 reviews)
"Beautiful view. Nice house. Very accommodating as far as house and host!"
United States
Jane O.
$191 nightly
The price is $202
Oct 18 - Oct 19
Total with taxes and fees
Island House On Mississippi River
A modern kitchen with dark cabinetry, a stainless steel refrigerator, a large island with bar stools, and pendant lighting.

5. Stay Where History Has a Heartbeat - Mike Wolfe's Two Lanes Guesthouse

Stay Where History Has a Heartbeat - Mike Wolfe's Two Lanes Guesthouse
Le Claire
10.0 out of 10, Exceptional, (17 reviews)
"Everything you could ask for- location, amenities, cleanliness, awesomeness…just amazing!"
United States
william c.
$417 nightly
The price is $467
Oct 18 - Oct 19
Total with taxes and fees
Stay Where History Has a Heartbeat - Mike Wolfe's Two Lanes Guesthouse
A living room with a sectional sofa, ottoman, and a dining area in the background.

6. Charming 1920s, pet friendly home, centrally located!

Charming 1920s, pet friendly home, centrally located!
Rock Island
9.2 out of 10, Wonderful, (47 reviews)
"The house was perfect for our stay for the bowling tournament. "
United States
ALYSIA R.
$206 nightly
The price is $232
Oct 17 - Oct 18
Total with taxes and fees
Charming 1920s, pet friendly home, centrally located!
A deck with outdoor furniture, a blue umbrella, and a sign reading "The Porch Sit & Relax".

7. Aire Leclaire 2 bedroom home

Aire Leclaire 2 bedroom home
Le Claire
10.0 out of 10, Exceptional, (74 reviews)
"Very nice place with a great location for the area. Very clean and well stocked. Could not ask for more."
United States
Bill C.
$158 nightly
The price is $176
Oct 18 - Oct 19
Total with taxes and fees
Aire Leclaire 2 bedroom home
A kitchen with wooden cabinets, a stainless steel sink, a coffee maker, a toaster, and a blender.

8. 3BR/2BA Beauty near TBK sports complex. Right off I74, close to everything!

3BR/2BA Beauty near TBK sports complex. Right off I74, close to everything!
Bettendorf
9.8 out of 10, Exceptional, (73 reviews)
"Great house and easy check in process!"
United States
Dee M.
$276 nightly
The price is $309
Oct 18 - Oct 19
Total with taxes and fees
3BR/2BA Beauty near TBK sports complex. Right off I74, close to everything!
A modern kitchen with dark blue cabinets, a stainless steel stove, a microwave, and a dishwasher.

9. Renovated Historic Duplex East Davenport Village

Renovated Historic Duplex East Davenport Village
Davenport
10.0 out of 10, Exceptional, (11 reviews)
"Great stay. Great communication, and great location walking to village restaurants!"
United States
Joseph W.
$356 nightly
The price is $371
Oct 20 - Oct 21
Total with taxes and fees
Renovated Historic Duplex East Davenport Village
A terrace with outdoor seating and a view of a bridge and river.

10. The Nelson Lofts - Unit 1 (1 BR)

The Nelson Lofts - Unit 1 (1 BR)
Downtown Davenport
9.8 out of 10, Exceptional, (17 reviews)
"Very nice place and easy to check in!"
United States
Russ K.
$214 nightly
The price is $240
Oct 19 - Oct 20
Total with taxes and fees
The Nelson Lofts - Unit 1 (1 BR)
A rustic bar area with wooden furniture, a large metal pot decoration, and a view of the garden outside.

11. Experience a 3 bedroom historic apartment Rock Island, IL

Experience a 3 bedroom historic apartment Rock Island, IL
Rock Island
10.0 out of 10, Exceptional, (6 reviews)
"It was a very unique property with the perfect location for us!"
United States
Tim M.
$372 nightly
The price is $420
Oct 25 - Oct 26
Total with taxes and fees
Experience a 3 bedroom historic apartment Rock Island, IL
Outdoor seating with a fire pit, overlooking a waterfront with a bridge.

12. The Nelson Lofts - Unit 7 (2 BR)

The Nelson Lofts - Unit 7 (2 BR)
Downtown Davenport
9.8 out of 10, Exceptional, (36 reviews)
"Great location close to multiple breweries and restaurants. During the summer there's a great walking path across the street and a farmer's market close by. Condo was great for a quick get away and had everything we needed."
United States
Todd
$260 nightly
The price is $291
Oct 18 - Oct 19
Total with taxes and fees
The Nelson Lofts - Unit 7 (2 BR)
An outdoor patio with a fire pit, seating, and a pergola structure.

13. Studio | Free Breakfast, Indoor Pool & Hot Tub

Studio | Free Breakfast, Indoor Pool & Hot Tub
Davenport
10.0 out of 10, Exceptional, (1 review)
"The Suites were nice and clean. They were as advertised. The suite my partner and I had was a cozy little hotel sitting room with a TV and couch that was attached with a conjoining room that led to a bedroom. For the price, the style, the location and amenities, we would absolutely stay again and recommend it as well. "
United States
Malcolm T.
$158 nightly
The price is $177
Oct 25 - Oct 26
Total with taxes and fees
Studio | Free Breakfast, Indoor Pool & Hot Tub
A red door with the number 218, a wreath above it, and a brick wall with a lantern to the right.

14. Charming Carriage House near VanderVeer Park

Charming Carriage House near VanderVeer Park
Davenport
9.8 out of 10, Exceptional, (25 reviews)
"This was a perfect place for my visit to the area. The Carriage House had everything we needed. I would definitely stay here again."
United States
Angelique G.
$198 nightly
The price is $222
Oct 19 - Oct 20
Total with taxes and fees
Charming Carriage House near VanderVeer Park
A modern kitchen with white cabinetry, stainless steel appliances, and a central island.

15. Charming 3 bedroom Condo in Bettendorf with King Master Suite

Charming 3 bedroom Condo in Bettendorf with King Master Suite
Bettendorf
10.0 out of 10, Exceptional, (40 reviews)
"Well maintained, clean and quiet place to stay. Smooth check in/out. Would stay there again."
United States
Deb L.
$355 nightly
The price is $360
Oct 18 - Oct 19
Total with taxes and fees
Charming 3 bedroom Condo in Bettendorf with King Master Suite
An outdoor patio with a fire pit, seating, and a pergola structure.

16. Free Breakfast, Free Wi-Fi, Indoor Pool + Hot Tub | Comfy Suite

Free Breakfast, Free Wi-Fi, Indoor Pool + Hot Tub | Comfy Suite
Davenport
10.0 out of 10, Exceptional, (1 review)
"Nice Neighborhood"
United States
Robby G.
$406 nightly
The price is $455
Nov 15 - Nov 16
Total with taxes and fees
Free Breakfast, Free Wi-Fi, Indoor Pool + Hot Tub | Comfy Suite
A wooden deck with a railing, a window, and leafless trees in the background.

17. Lewis M. Fisher House

Lewis M. Fisher House
Davenport
8.6 out of 10, Excellent, (8 reviews)
"Great space to relax or have fun with the family. Lovely restored home. Good location for getting to attractions around the QC. "
United States
Owen K.
$391 nightly
The price is $438
Oct 20 - Oct 21
Total with taxes and fees
Lewis M. Fisher House
A bedroom with a bed, a dresser, a nightstand, a ceiling fan, and a window with curtains.

18. Bettendorf Gem: 3BR Apartment w/ King Suite & Office!

Bettendorf Gem: 3BR Apartment w/ King Suite & Office!
Bettendorf
10.0 out of 10, Exceptional, (3 reviews)
"Home was great and as described. Clean and very close to many restaurants and places we needed to be."
United States
Zach B.
$355 nightly
The price is $360
Oct 18 - Oct 19
Total with taxes and fees
Bettendorf Gem: 3BR Apartment w/ King Suite & Office!
A living room with a brown sectional sofa, a coffee table, and a bookshelf.

19. Safe & Spacious 3BR/3BA family and pet friendly home near TBK sports complex

Safe & Spacious 3BR/3BA family and pet friendly home near TBK sports complex
Davenport
9.8 out of 10, Exceptional, (51 reviews)
"We were thankful for a dog friendly home that had a fenced in backyard. After a week of traveling our dogs loved it."
United States
Michele B.
$274 nightly
The price is $307
Oct 18 - Oct 19
Total with taxes and fees
Safe & Spacious 3BR/3BA family and pet friendly home near TBK sports complex
A terrace with outdoor seating and a view of a bridge and river.

20. The Nelson Lofts - Unit 4 (2 BR)

The Nelson Lofts - Unit 4 (2 BR)
Downtown Davenport
9.8 out of 10, Exceptional, (33 reviews)
"We stayed for a couple nights with two young kids—would definitely recommend! The location is great and the loft was very clean and comfortable."
United States
Ashley H.
$253 nightly
The price is $284
Oct 18 - Oct 19
Total with taxes and fees
The Nelson Lofts - Unit 4 (2 BR)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Osco Hotel Reviews

Hyatt House East Moline Quad Cities

Hyatt House East Moline Quad Cities

10/10 Excellent
"Kudos to all involved! Team Hyatt did a superb job welcoming me during both checking in, and checking out! I commend their service!"
Kevin 1-night trip
Posted 1 hour ago
Hyatt House East Moline Quad Cities

Find out more about Osco

Everything you need to know about Osco vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Osco vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Osco vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Osco vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Osco. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Osco in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $138 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Osco rentals

At Expedia, we put the best Osco vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Osco rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Osco vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Osco. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find a vacation rental in Osco?

Yes, you can find vacation rentals near popular local attractions in Osco, or you can select a secluded option if you'd like a relaxing place to stay.

What are some of the best vacation home rentals in Osco?

Modern Woodland Retreat on 107 Acres, 5BR/4BA, Le Claire, IA: Visitors like this Osco vacation home rental. It offers a patio, a garden, and air-conditioning to help you feel perfectly comfortable in your new surroundings.

What’s there to see and do in Osco?

Explore the area and family-friendly sights such as Niabi Zoo, or get out into nature at a spot like Greenvalley Sports Complex. TPC Deere Run Golf Course and Deere and Company World Headquarters are a couple of places you'll find in the larger area.

What’s a vacation rental in Osco like?

Vacation rentals are privately owned properties you can stay in for short or long periods in Osco. Vacation rentals offer extras such as hot tubs, fire pits, and patios so you'll have a home away from home. If you're concerned about a sanitized environment, vacation rentals can provide a sense of safety away from public hotel elevators and busy concierge desks while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a popular choice for families.