Visit Otay Mesa West
Popular places to visit
San Diego Zoo
See nature up-close and personal at one of the country’s largest and most educational zoos.
San Diego Convention Center
Whether you come for Comic-Con or a medical convention, this huge gathering place in the Marina District of San Diego will more than satisfy your needs.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
Mission Beach
A favorite vacation spot for 100 years, this seaside village combines old-fashioned charm with modern amenities.
SeaWorld
Visit one of the world’s largest marine parks for talented and amazing and animals, electrifying rides, conservation education and seasonal events.
Things to do
San Diego Sunset Cruise from Mission Bay
San Diego Old Town Trolley Hop-On Hop-Off Tour
San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway
Otay Mesa West Hotel Deals
Hampton Inn & Suites by Hilton San Diego SeaWorld
A nice, clean Hampton Inn. Everything that you would expect
Reviewed on Oct 27, 2025
Comfort Inn San Diego Airport At The Harbor
Short walk to the Harbor Walk and eateries. Parking may be challenging. The pool deck and pool were clean and inviting. Busy street, there will be noise.
Reviewed on Oct 27, 2025
Manchester Grand Hyatt San Diego
Staff was friendly and room was clean
Reviewed on Oct 25, 2025
Hilton San Diego Mission Valley
Didn’t use the pool but area very well maintained Only negative comment Saturday morning went to the front desk to have only our beds made . Came back to the hotel at 7:00 pm beds were not made very disappointing I did call when I came back to my room the front desk so the supervisor of my housekeeper ...
Reviewed on Oct 28, 2025
Pendry San Diego
The rooms were very nice and the location is perfect for San Diego. It's a very nice hotel.
Reviewed on Oct 22, 2025
Hard Rock Hotel San Diego
Staff was great. My only two complaint is. The main lobby is over powering with some type of air freshener. And also our balcony door did not lock. It is very noisy at night but you are in down town where all the night life is. It’s a nice stay for sure.
Reviewed on Oct 26, 2025
Other neighborhoods around Otay Mesa West
Gaslamp Quarter
Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.
Downtown San Diego
Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.
Little Italy
Little Italy is popular for its captivating waterfront views. Explore top sights like Maritime Museum of San Diego and San Diego Bay, and you can get around town on the metro at County Center - Little Italy Station.
North Park
North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and San Diego Natural History Museum.
Mid-City
If you're spending time in Mid-City, check out sights like Cal Coast Credit Union Open Air Theater or Viejas Arena and hop on the metro to see more the city at SDSU Transit Center Station or Alvarado Station.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.
Otay Mesa West, CA
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