San Nicolás Vacations from $622

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Your San Nicolás Vacation

If you're wanting a food-lovers retreat, our San Nicolás vacation packages are what you need. Whether you're searching for shopping, nightlife or bars and pubs, this neighborhood has a bit of something for every traveler. Some leading nearby attractions to check out during your trip to San Nicolás include Obelisco, Colón Theatre and Casa Rosada. Expedia will help put your travel plans into action. Book your dream San Nicolás vacation now.

The Latest San Nicolás Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Casa Joseph

Casa Joseph

Palermo
$622
per person
Nov 29 - Dec 2
found 1 day ago
Roundtrip flight included
Lima (LIM) to Buenos Aires (EZE)
9.4/10 Exceptional! (553 reviews)
Excellent location. And staff was very nice

Reviewed on Sep 23, 2026

Estancia Villa Maria

Estancia Villa Maria

$1,227
per person
Dec 26 - Dec 30
found 1 hour ago
Roundtrip non-stop flight included
San Juan (SJU) to Buenos Aires (EZE)
9.4/10 Exceptional! (114 reviews)
Beautiful property

Reviewed on Sep 24, 2026

MOT + Soria 5122 - 4 Bedroom Pool & Grill Palermo Soho

MOT + Soria 5122 - 4 Bedroom Pool & Grill Palermo Soho

Palermo
Save 100% on your flight
$4,016
per person
Nov 11 - Nov 18
found 6 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Buenos Aires (EZE)
6/10 (1 review)
The hotel was nice and good area. But very cold and not very clean bathrooms. The check in process was very lengthy

Reviewed on Jun 5, 2026

 MOT Teatro Soho

MOT Teatro Soho

Palermo
$2,785
per person
Nov 11 - Nov 18
found 6 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Buenos Aires (EZE)
No reviews
MOT Costa Rica 4300

MOT Costa Rica 4300

Palermo
$2,059
per person
Nov 11 - Nov 18
found 6 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Buenos Aires (EZE)
No reviews

Where to stay in San Nicolás

Find the best San Nicolás areas and neighborhoods for the activities you enjoy most. Learn more about San Nicolás
A red bridge over a pond with people walking on it, surrounded by lush green trees and a stone lantern.

Palermo

1 out of top 10 points of interest in this area

Home to the Galileo Galilei planetarium and Buenos Aires Japanese Gardens, this neighborhood boasts a fashionable area for fashion, design, and street culture in Palermo Soho. Easily accessible via Underground Line D and commuter railways.

A modern building with a large 'R' logo and the name 'recoleta mall'.

Recoleta

1 out of top 10 points of interest in this area

One of the city’s grandest and most elegant neighborhoods is also the final resting place of leading figures from Argentina’s history.

A waterfront cityscape with modern high-rise buildings, including a Hilton hotel, reflecting in calm waters.

Puerto Madero

Explore trendy Puerto Madero's high-rise buildings, luxurious hotels, and modern architecture. Visit museums like Faena Arts Center, admire Puente de la Mujer, and enjoy elegant dining options.

A historic building with a prominent clock tower and a green construction site nearby.

El Centro

6 out of top 10 points of interest in this area

This area plays many roles in Buenos Aires, from financial district and political hub, to tourist center and shopping precinct.

A red sports car parked in front of a colorful building with a sun design on the wall and a sign that reads "Alimentos Naturales, Integrales, Orgánicos Certificados".

Palermo Viejo

The lively heart of Buenos Aires’s largest neighborhood has artisan markets and boutiques, pretty plazas, eclectic restaurants and great nightlife.

San Nicolás Hotel Deals

Gran Hotel Argentino

Gran Hotel Argentino

Carlos Pellegrini 37 Buenos Aires BUE
Fully refundableReserve now, pay when you stay
$44 nightly
$47 total
Oct 4 - Oct 5
7.4/10 Good! (1,001 reviews)
"The room was clean and tidy but needs some touch ups with the paint peeling on the ceiling and air con plug. It gives hostel vibes. The staff were helpful and friendly. Hotel is located in a nice spot handy to restaurants and cafes"

Reviewed on Oct 1, 2026

Gran Hotel Argentino
NH Collection Buenos Aires Jousten

NH Collection Buenos Aires Jousten

Av. Corrientes 280 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
$138 nightly
$141 total
Oct 17 - Oct 18
8.8/10 Excellent! (616 reviews)
"Hotel bien ubicado cerca de Puerto Madero, Obelisco y Casa Rosada. El staff es amable y el desayuno es bueno. El hotel está en buenas condiciones pero se ve que se encuentra un poco viejo en algunas cosas, por ejemplo el baño."

Reviewed on Oct 1, 2026

NH Collection Buenos Aires Jousten
Grand Brizo Buenos Aires

Grand Brizo Buenos Aires

Cerrito 180 Buenos Aires
Fully refundableReserve now, pay when you stay
$216 nightly
$219 total
Oct 5 - Oct 6
9.4/10 Exceptional! (885 reviews)
"The staff were very friendly and very clean!"

Reviewed on Sep 30, 2026

Grand Brizo Buenos Aires
See all 3,650 properties in San Nicolás
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular San Nicolás attractions

A cityscape with a prominent obelisk, a Pepsi billboard, and the Panamericano building.

Obelisco

9.0/10 (5,628 reviews)
This giant pillar was built to mark the 400th anniversary of the city’s inception. Now, it stands as the most famous icon in Buenos Aires.
See properties
A grand neoclassical building with a large arched entrance and a blue canopy.

Colón Theatre

9.2/10 (4,178 reviews)
Visit one of the world’s finest theaters to watch operas, ballets and concerts or take a guided tour of the salons and auditorium.
See properties
A historic building with ornate architecture and red awnings, likely a shopping area.

Galerias Pacifico

8.8/10 (1,426 reviews)
During your trip to Buenos Aires, you can browse for the perfect souvenirs at Galerias Pacifico. Experience the acclaimed art scene and fascinating museums in this culturally rich area.
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A church interior with high vaulted ceilings and rows of pews.

Buenos Aires Metropolitan Cathedral

9.0/10 (815 reviews)
Visit this grand cathedral to admire a range of architectural styles, see the tombs of Argentine heroes and enjoy free live music events.
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A large building with a sign reading "Palácio de los Deportes" and a mural of athletes.

Luna Park Stadium

8.4/10 (110 reviews)
Catch an event at Luna Park Stadium during your trip to Buenos Aires. Make time for the shops and local tours in this vibrant area.
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A darkened theater interior with a large illuminated sign reading "PUCHA".
Photo by Carolzinha

Paseo La Plaza

8.8/10 (12 reviews)
During your visit to Buenos Aires, you can search for that perfect souvenir at Paseo La Plaza. Experience the fascinating museums and acclaimed art scene in this vibrant area.
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Gran Rex Theatre

8.2/10 (21 reviews)
Enjoy a show at Gran Rex Theatre, a storied theater in Buenos Aires. Discover the acclaimed art scene in this culturally rich area, or seek out the local tours.
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Centro Cultural Kirchner

7.6/10 (53 reviews)
Enjoy an outing to Centro Cultural Kirchner during your stay in Buenos Aires. Discover the acclaimed art scene and shops in this culturally rich area.
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Things to do

Buenos Aires: La Boca Guided Walking Tour in English

Buenos Aires: La Boca Guided Walking Tour in English

$13
per adult
94% of travellers recommend
Buenos Aires: La Boca Guided Walking Tour in English
Buenos Aires: La Recoleta Cemetery Guided Tour in English

Buenos Aires: La Recoleta Cemetery Guided Tour in English

$12
per adult
92% of travellers recommend
Buenos Aires: La Recoleta Cemetery Guided Tour in English
Piazzolla Tango Dinner & Tango Show

Piazzolla Tango Show with Optional Dinner in Buenos Aires

$35
per adult
100% of travellers recommend
Piazzolla Tango Show with Optional Dinner in Buenos Aires
See all activities in Buenos Aires

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.