A neoclassical building with columns and a central pediment, surrounded by a grassy area and a tree.
Photo by Jan Lalkens
Open Photo by Jan Lalkens

San Nicolás Vacations from $1,230

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Your San Nicolás Vacation

If you're wanting a food-lovers retreat, our San Nicolás vacation packages are what you need. Whether you're searching for shopping, nightlife or bars and pubs, this neighborhood has a bit of something for every traveler. Some leading nearby attractions to check out during your trip to San Nicolás include Obelisco, Colón Theatre and Casa Rosada. Expedia will help put your travel plans into action. Book your dream San Nicolás vacation now.

The Latest San Nicolás Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • A large, traditional Tudor-style house with a well-maintained lawn and garden.
    Jan 22 - Jan 27

    Estancia Villa Maria + Flight

    Spegazzini
    4 nights
    4.5 star property
    9.4/10 - Exceptional (120 reviews)
    Roundtrip • New York (EWR) - Buenos Aires (EZE)
    EWR - EZE • 1 stop EZE - EWR • 1 stop
    $1,980
    $1,230
    per traveler
    found 1 day ago
    Estancia Villa Maria
  • A person lying on a bed in a room with a large window, reading a book. There are two baskets on the bed, one with pastries and the other with a drink.
    Dec 24 - Dec 31

    Krista Boutique Hotel + Flight

    Palermo
    6 nights
    4.0 star property
    9.2/10 - Wonderful (395 reviews)
    "Helpful staff, bright, modern clean rooms, great location. Would definitely recommend and stay here again."
    Reviewed October 28, 2026
    Roundtrip • Miami (MIA) - Buenos Aires (EZE)
    MIA - EZE • Nonstop EZE - MIA • 1 stop
    Save 100% on your flight
    $2,718
    $1,651
    per traveler
    found 1 day ago
    Krista Boutique Hotel
  • A modern living room with a sofa, a round table, and a view of a cityscape through large windows.
    Dec 24 - Dec 31

    SLS Buenos Aires Puerto Madero + Flight

    Puerto Madero
    6 nights
    5.0 star property
    9.6/10 - Exceptional (405 reviews)
    Roundtrip • Miami (MIA) - Buenos Aires (EZE)
    MIA - EZE • Nonstop EZE - MIA • 1 stop
    Save 100% on your flight
    $3,444
    $2,155
    per traveler
    found 1 day ago
    SLS Buenos Aires Puerto Madero
  • A spacious living room with a sofa, armchairs, a coffee table, and a bookshelf.
    Jan 22 - Jan 27

    Algodon Mansion + Flight

    Buenos Aires Central Business District
    4 nights
    5.0 star property
    9.6/10 - Exceptional (124 reviews)
    "Beautiful room, excellent service in a great area. I highly recommend it."
    Reviewed November 8, 2026
    Roundtrip • Los Angeles (LAX) - Buenos Aires (EZE)
    LAX - EZE • 1 stop EZE - LAX • 1 stop
    $2,444
    $1,556
    per traveler
    found 1 day ago
    Algodon Mansion
  • A covered outdoor seating area with white wicker tables and chairs, surrounded by lush green foliage.
    Jan 20 - Jan 27

    Loi Suites Recoleta Hotel + Flight

    Recoleta
    6 nights
    4.5 star property
    9.2/10 - Wonderful (873 reviews)
    Roundtrip • Los Angeles (LAX) - Buenos Aires (EZE)
    LAX - EZE • 1 stop EZE - LAX • 1 stop
    Save 100% on your flight
    $2,449
    $1,591
    per traveler
    found 1 day ago
    Loi Suites Recoleta Hotel

Where to stay in San Nicolás

Find the best San Nicolás areas and neighborhoods for the activities you enjoy most.
A church with a bell tower and a clock, surrounded by a fence and flower beds.

Recoleta

One of the city’s grandest and most elegant neighborhoods is also the final resting place of leading figures from Argentina’s history.

A modern spherical building with a glass facade and a unique architectural design.

Palermo

Home to the Galileo Galilei planetarium and Buenos Aires Japanese Gardens, this neighborhood boasts a fashionable area for fashion, design, and street culture in Palermo Soho. Easily accessible via Underground Line D and commuter railways.

A modern cityscape with a prominent bridge and tall buildings.

Puerto Madero

Explore trendy Puerto Madero's high-rise buildings, luxurious hotels, and modern architecture. Visit museums like Faena Arts Center, admire Puente de la Mujer, and enjoy elegant dining options.

A red sports car parked in front of a colorful building with a sun design on the wall and a sign that reads "Alimentos Naturales, Integrales, Orgánicos Certificados".

Palermo Viejo

The lively heart of Buenos Aires’s largest neighborhood has artisan markets and boutiques, pretty plazas, eclectic restaurants and great nightlife.

A large equestrian statue, a domed building, and a cityscape at dusk.

El Centro

This area plays many roles in Buenos Aires, from financial district and political hub, to tourist center and shopping precinct.

Discover the most popular places to visit in San Nicolás

A cityscape with a prominent obelisk, a Pepsi billboard, and the Panamericano building.

Obelisco

9.0/10 (5,628 reviews)
This giant pillar was built to mark the 400th anniversary of the city’s inception. Now, it stands as the most famous icon in Buenos Aires.
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What to do near San Nicolás

Buenos Aires: La Recoleta Cemetery Guided Tour in English

Buenos Aires: La Recoleta Cemetery Guided Tour in English

$12
per adult
92% of travelers recommend
Buenos Aires: La Recoleta Cemetery Guided Tour in English
See all activities near San Nicolás

San Nicolás Hotel Deals

A bar area with chairs and tables, a city view through a glass railing, and decorative lanterns.

Grand Brizo Buenos Aires

Grand Brizo Buenos Aires
4.0 star property
San Nicolás
9.4 out of 10, Exceptional, (902 reviews)
"Staff and room were very good. Breakfast was ok."
$168 nightly
The price is $171
Dec 2 - Dec 3
Grand Brizo Buenos Aires
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
See all properties in San Nicolás
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.