Find hotels in Sanctuary On Spruce Creek, Port Orange

Start date: Check-in selected.
To Date
End date: Check-out

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Sanctuary On Spruce Creek hotels

Holiday Inn Express & Suites Deland South by IHG

Holiday Inn Express & Suites Deland South by IHG
2.5 star property
17.2 mi from Sanctuary On Spruce Creek
9.2 out of 10, Wonderful, (693)
"Great stay, Great Breakfast, Great Staff. "
United States
Javier
$86 nightly
The price is $97
Dec 14 - Dec 15
Total with taxes and fees
Holiday Inn Express & Suites Deland South by IHG

Comfort Inn & Suites DeLand - near University

Comfort Inn & Suites DeLand - near University
2.5 star property
16 mi from Sanctuary On Spruce Creek
8.2 out of 10, Very Good, (1001)
"Nice staff food was good. It was pleasant. Would recommend it. "
United States
Camilla and James
$80 nightly
The price is $90
Dec 16 - Dec 17
Total with taxes and fees
Comfort Inn & Suites DeLand - near University

Daytona Grande Oceanfront Resort

Daytona Grande Oceanfront Resort
4.0 star property
10.6 mi from Sanctuary On Spruce Creek
9.2 out of 10, Wonderful, (4200)
"Wonderful place to stay "
United States
Stacey
$141 nightly
The price is $159
Dec 24 - Dec 25
Total with taxes and fees
Daytona Grande Oceanfront Resort

Courtyard by Marriott DeLand Historic Downtown

Courtyard by Marriott DeLand Historic Downtown
3.0 star property
16.7 mi from Sanctuary On Spruce Creek
8.8 out of 10, Excellent, (713)
"Clean and kind! "
United States
Elizabeth
$101 nightly
The price is $114
Dec 21 - Dec 22
Total with taxes and fees
Courtyard by Marriott DeLand Historic Downtown

Coral Sands Inn

Coral Sands Inn
2.5 star property
16.2 mi from Sanctuary On Spruce Creek
9.4 out of 10, Exceptional, (1269)
"Very nice stay."
United States
Alberto
$99 nightly
The price is $111
Dec 11 - Dec 12
Total with taxes and fees
Coral Sands Inn

Quality Inn near Blue Spring

Quality Inn near Blue Spring
2.5 star property
18.7 mi from Sanctuary On Spruce Creek
7.2 out of 10, Good, (932)
"Room was actually not that bad. Looks like they have recently put new floors (not carpet) which is always a bonus at motels. New paint and the bed wasn’t bad either. For the price it was right there on point, for the experience which was nothing special. If you’re looking for a decent motel that’s not too ghetto then it will do. "
United States
Beau
$81 nightly
The price is $91
Dec 16 - Dec 17
Total with taxes and fees
Quality Inn near Blue Spring

Holiday Inn Express & Suites Orange City - Deltona by IHG

Holiday Inn Express & Suites Orange City - Deltona by IHG
2.5 star property
18.8 mi from Sanctuary On Spruce Creek
9.0 out of 10, Wonderful, (1001)
"It was a great place to stay at"
United States
Luis
$90 nightly
The price is $101
Jan 5 - Jan 6, 2026
Total with taxes and fees
Holiday Inn Express & Suites Orange City - Deltona by IHG

Days Inn by Wyndham Daytona Oceanfront

Days Inn by Wyndham Daytona Oceanfront
2.5 star property
6.2 mi from Sanctuary On Spruce Creek
8.6 out of 10, Excellent, (1939)
"Everyone is super friendly great place to stay and relax"
United States
Liss
$84 nightly
The price is $93
Dec 14 - Dec 15
Total with taxes and fees
Days Inn by Wyndham Daytona Oceanfront

Hilton Daytona Beach Oceanfront Resort

Hilton Daytona Beach Oceanfront Resort
4.0 star property
10.2 mi from Sanctuary On Spruce Creek
7.4 out of 10, Good, (5001)
"Really enjoyed my stay."
United States
Stephano
$128 nightly
The price is $144
Dec 21 - Dec 22
Total with taxes and fees
Hilton Daytona Beach Oceanfront Resort

Lotus Boutique Inn & Suites

Lotus Boutique Inn & Suites
3.0 star property
13.6 mi from Sanctuary On Spruce Creek
7.6 out of 10, Good, (1391)
"Absolutely love this place… I will definitely be returning in the Spring!"
United States
Jeanne
$79 nightly
The price is $89
Dec 11 - Dec 12
Total with taxes and fees
Lotus Boutique Inn & Suites

Extended Stay America Premier Suites Daytona Beach Ormond Be

Extended Stay America Premier Suites Daytona Beach Ormond Be
2.5 star property
12.8 mi from Sanctuary On Spruce Creek
8.6 out of 10, Excellent, (1003)
"Nice property friendly staff"
United States
Shanna
$79 nightly
The price is $89
Dec 16 - Dec 17
Total with taxes and fees
Extended Stay America Premier Suites Daytona Beach Ormond Be

Clarion Inn Ormond Beach at Destination Daytona

Clarion Inn Ormond Beach at Destination Daytona
2.5 star property
18.7 mi from Sanctuary On Spruce Creek
8.2 out of 10, Very Good, (922)
"clean, well-staffed, friendly, helpful, close to dining options, safe"
United States
Jan
$84 nightly
The price is $95
Dec 13 - Dec 14
Total with taxes and fees
Clarion Inn Ormond Beach at Destination Daytona

Super 8 by Wyndham Ormond Beach

Super 8 by Wyndham Ormond Beach
2.0 star property
18.6 mi from Sanctuary On Spruce Creek
7.2 out of 10, Good, (1001)
"Super 8 was clean, comfortable, and despite being near the interstate (convenient) was pretty quiet. Many food options nearby. Staff was friendly and responsive to my questions. Definitely recommend for a low cost hotel"
United States
Catherine
$67 nightly
The price is $75
Dec 11 - Dec 12
Total with taxes and fees
Super 8 by Wyndham Ormond Beach

Hilton Vacation Club The Cove on Ormond Beach

Hilton Vacation Club The Cove on Ormond Beach
3.0 star property
14.2 mi from Sanctuary On Spruce Creek
9.0 out of 10, Wonderful, (1005)
"This was one of my fave resorts in Daytona Beach. Beautiful water front views, nice staffs, clean, quiet, easy parking. I felt very comfortable and convenient when I stayed. "
United States
Enyi
$119 nightly
The price is $134
Dec 14 - Dec 15
Total with taxes and fees
Hilton Vacation Club The Cove on Ormond Beach

Sleep Inn Ormond Beach - Daytona

Sleep Inn Ormond Beach - Daytona
2.5 star property
12.9 mi from Sanctuary On Spruce Creek
7.6 out of 10, Good, (1006)
"Staff is very nice."
United States
Jenna
$56 nightly
The price is $62
Dec 17 - Dec 18
Total with taxes and fees
Sleep Inn Ormond Beach - Daytona

Nautilus Inn

Nautilus Inn
2.5 star property
9 mi from Sanctuary On Spruce Creek
9.2 out of 10, Wonderful, (3029)
"Friendly staff, clean room"
United States
Kent
$105 nightly
The price is $118
Dec 14 - Dec 15
Total with taxes and fees
Nautilus Inn

Home2 Suites by Hilton Ormond Beach Oceanfront

Home2 Suites by Hilton Ormond Beach Oceanfront
3.0 star property
13.2 mi from Sanctuary On Spruce Creek
9.2 out of 10, Wonderful, (990)
"Love the place, it was family friendly "
United States
Andy
$119 nightly
The price is $134
Dec 17 - Dec 18
Total with taxes and fees
Home2 Suites by Hilton Ormond Beach Oceanfront

Hard Rock Hotel Daytona Beach

Hard Rock Hotel Daytona Beach
4.0 star property
11 mi from Sanctuary On Spruce Creek
9.2 out of 10, Wonderful, (1624)
"Excellent service from the entire staff, we had a great stay."
United States
Joshua
$181 nightly
The price is $199
Dec 11 - Dec 12
Total with taxes and fees
Hard Rock Hotel Daytona Beach

Comfort Inn & Suites Ormond Beach Oceanfront

Comfort Inn & Suites Ormond Beach Oceanfront
2.5 star property
14 mi from Sanctuary On Spruce Creek
8.0 out of 10, Very Good, (746)
"Everything was good and clean. Courteous and friendly staff"
United States
Jasmine
$88 nightly
The price is $99
Dec 14 - Dec 15
Total with taxes and fees
Comfort Inn & Suites Ormond Beach Oceanfront

Max Beach Resort

Max Beach Resort
3.5 star property
8.8 mi from Sanctuary On Spruce Creek
9.6 out of 10, Exceptional, (916)
"My favorite place to stay in Daytona!"
United States
Justin
$232 nightly
The price is $261
Dec 15 - Dec 16
Total with taxes and fees
Max Beach Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sanctuary On Spruce Creek

Find the best Sanctuary On Spruce Creek areas and neighborhoods for the activities you enjoy most.

Carter Norwood

While there might not be top attractions in Carter Norwood, you can explore the larger area and discover places like Ponce de Leon Inlet Lighthouse and Museum and Sunglow Fishing Pier.

Halifax Estates

While Halifax Estates isn't home to many top sights, Ponce de Leon Inlet Lighthouse and Museum and Sunglow Fishing Pier are some notable places to visit nearby.

Winthrop Holding

If you're looking for some top things to see and do in Winthrop Holding and surrounding area, you can visit Sunglow Fishing Pier and Ponce de Leon Inlet Lighthouse and Museum.

Fly In Spruce Creek

If you're looking for some top things to see and do in Fly In Spruce Creek and surrounding area, you can visit Spruce Creek Country Club and Crane Lakes Golf and Country Club.

Spruce Creek

Spruce Creek might not have many top sights, but Spruce Creek Country Club and Airport Road Park are two attractions nearby that you can check out.

Top Sanctuary On Spruce Creek Hotel Reviews

Frequently asked questions

Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Sanctuary On Spruce Creek hotel for you.
How can I save on a Sanctuary On Spruce Creek hotel booking with Expedia?
One Key™ - Expedia's free travel rewards program - gives you instant access to perks and Member Prices on Sanctuary On Spruce Creek hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings.

*OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Sanctuary On Spruce Creek hotel?
Hotel prices in Sanctuary On Spruce Creek often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

Explore a world of travel with Expedia