Santa Cruz

Travel Guide

City Express by Marriott Nogales

City Express by Marriott Nogales

3 out of 5
Prolongacion Alvaro Obregon #4200 Nogales SON
$79 nightly
The price is $88 total per night from Nov 8 to Nov 9
$88 total
Nov 8 - Nov 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Nogales. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
City Express by Marriott Nogales
Fairfield Inn & Suites by Marriott Nogales

Fairfield Inn & Suites by Marriott Nogales

3.5 out of 5
Boulevard El Greco 45, Calle Arcadias Nogales SON
$119 nightly
The price is $132 total per night from Nov 20 to Nov 21
$132 total
Nov 20 - Nov 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Nogales. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Fairfield Inn & Suites by Marriott Nogales
Fiesta Inn Nogales

Fiesta Inn Nogales

3.5 out of 5
Calzada Ind Nuevo Nogales 3 Nogales SON
$84 nightly
The price is $101 total per night from Nov 9 to Nov 10
$101 total
Nov 9 - Nov 10
Total with taxes and fees
Book a stay at this business-friendly hotel in Nogales. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
Fiesta Inn Nogales
See all 27 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Charming 2-bedroom house with WiFi, AC in beautiful Cananea

Charming 2-bedroom house with WiFi, AC in beautiful Cananea

Cananea Son.
Stay at this vacation home in Cananea. Enjoy patios, in-room fireplaces, and air conditioning. Popular attractions Plaza Principal and Historic Cananea Jail ...
10/10 Exceptional! (1 review)
"Nice place. Very friendly and helpful host. Thank you."

Reviewed on May 21, 2026

Charming 2-bedroom house with WiFi, AC in beautiful Cananea
Beautiful studio near the consulate, fully furnished.

Beautiful studio near the consulate, fully furnished.

Moderna Heroica Nogales SON
Stay at this apartment in Nogales. Enjoy laundry facilities, patios, and air conditioning. Popular attractions Galería Plaza Norte and Unidad Deportiva are located ...
Beautiful studio near the consulate, fully furnished.
3-Bedroom House Near IMSS 15 and the Consulate | We Provide Invoices and Pet-Friendly

3-Bedroom House Near IMSS 15 and the Consulate | We Provide Invoices and Pet-Friendly

Heroica Nogales Son.
Stay at this vacation home in Nogales. Enjoy free WiFi, laundry facilities, and air conditioning. Popular attractions La Pirinola Hill and Nogales Mall are located ...
3-Bedroom House Near IMSS 15 and the Consulate | We Provide Invoices and Pet-Friendly
See all properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

When is the best time to visit Santa Cruz?
The best time to visit Santa Cruz is from February through May, when the weather is pleasant for exploring. For travelers seeking fewer crowds and better value, the quieter months of December and January are a good option, offering cooler temperatures.
Can I book a refundable hotel in Santa Cruz?
Yes, Expedia offers many flexible booking options, and you can look for refundable hotels in Santa Cruz by entering your dates and using the refundable or fully refundable filter. Always check the hotel's cancellation policy before you book, since terms can vary by hotel, and visit Expedia help center for further details.
Why book a trip to Santa Cruz with Expedia?
Expedia makes it easier to plan your Santa Cruz trip with travel tools, flexible search options, and bookable trip components all in one place. You can organize your plans in one account and use Expedia to help build a trip that fits your budget and travel style. Find out more about how by visiting Expedia's Trip Planner page.
Should I stay in a hotel or vacation rental in Santa Cruz?
The best choice depends on your travel style. Hotels in Santa Cruz can be a good fit for convenience, on-site amenities, and shorter stays, while vacation rentals may offer more space, privacy, and home-style amenities for longer trips, families, or groups. With Expedia, you can compare both options side by side, read traveler reviews, and filter by amenities to find the right fit for your trip.
How can I manage my Santa Cruz trip on Expedia?
Once you've booked your Santa Cruz trip, you can manage it through your Expedia account or the Expedia app. You can view your itinerary, access booking details, make eligible changes, and check for updates in My Trips. The Expedia app can also help you stay organized while you travel.
What if I need help during my Santa Cruz trip?
Expedia offers customer support before, during, and after your Santa Cruz trip. If your plans change or something unexpected happens, you can review your booking in My Trips and use Expedia help center channels for help with eligible changes, cancellations, or travel issues.
How can Expedia help me plan my first trip to Santa Cruz?
If it's your first trip to Santa Cruz, Expedia can help you plan by bringing together stays, flights, activities, traveler reviews, and trip-planning tools in one place. With Expedia's Trip Planner you can compare options, read reviews from other travelers, and build an itinerary that matches your interests and budget.
How can I save on my Santa Cruz hotel booking with Expedia?
Join One Key™ for free to unlock instant discounts with Member Prices on select hotels. You can also earn and use OneKeyCash™* on eligible bookings on Expedia. Booking in advance is usually another great way to save on your Santa Cruz hotel.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

Cities near Santa Cruz

A town nestled in a valley with mountains in the background.

Nogales

A rugged mountainous landscape with prominent rocky formations and a flat-topped hill in the center.

Patagonia

A mountainous landscape with a cloudy sky and lightning strikes.

Hereford

A close-up of blue and silver mineral formations.

Cananea

Explore a world of travel with Expedia