Title: Visit Santa Isabel: 2026 Travel Guide for Santa Isabel, Chihuahua | Expedia.com [Hotels in Santa Isabel](https://expedia.com/Santa-Isabel-Hotels.d553248635640632170.Travel-Guide-Hotels)[Vacation Rentals in Santa Isabel](https://expedia.com/Santa-Isabel-Vacation-Rentals.d553248635640632170.Travel-Guide-VacationRentals)[Car Rentals in Santa Isabel](https://expedia.com/Car-Rentals-In-Santa-Isabel.d553248635640632170.Car-Rental-Guide)[Santa Isabel Vacation Packages](https://expedia.com/Santa-Isabel.d553248635640632170.Destination-Travel-Guides) # Santa Isabel ## Travel Guide ![Santa Isabel, Chihuahua, Mexico](https://images.trvl-media.com/place/553248635640632170/e78afccd-0d19-4066-ae9e-63a36721ea86.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santa Isabel, Chihuahua, Mexico](https://images.trvl-media.com/place/553248635640632170/e78afccd-0d19-4066-ae9e-63a36721ea86.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santa Isabel, Chihuahua, Mexico](https://images.trvl-media.com/place/553248635640632170/3478658b-e426-4a4d-affe-3363ef07c46d.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santa Isabel, Chihuahua, Mexico](https://images.trvl-media.com/place/553248635640632170/81cddb9b-3899-48a4-8dfe-834b1dea0432.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Santa Isabel ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=DX_SPRING_PROMO_553248635640632170) - Santa Isabel Hotel Deals - Vacation Rentals in Santa Isabel ![Hotel Sicomoro](https://images.trvl-media.com/lodging/1000000/10000/5300/5272/84030b4b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Sicomoro Boulevard Antonio Ortiz Mena 411 Chihuahua CHIH $44 nightly $53 total Feb 14 - Feb 15 Total with taxes and fees Book a stay at this business-friendly hotel in Chihuahua. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ... 8.2/10 Very Good! (1,016 reviews) The room was very good and clean 👌 Reviewed on Feb 2, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F14%2F2026&endDate=2%2F15%2F2026&selected=5272&PinnedHotelID=5272&HadPinnedHotel=true®ionId=553248635640632170) ![Hotel María Bonita Chihuahua](https://images.trvl-media.com/lodging/93000000/92940000/92935000/92934976/35a03779_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel María Bonita Chihuahua Periferico de la juventud 4114 Chihuahua CHIH $97 nightly $117 total Feb 15 - Feb 16 Total with taxes and fees Book a stay at this business-friendly hotel in Chihuahua. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Distrito Uno and District 1 ... 9.2/10 Wonderful! (1,032 reviews) Staff is amazing Reviewed on Feb 8, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F15%2F2026&endDate=2%2F16%2F2026&selected=92934976&PinnedHotelID=92934976&HadPinnedHotel=true®ionId=553248635640632170) ![Extended Suites Chihuahua La Juventud](https://images.trvl-media.com/lodging/29000000/28410000/28409900/28409866/05dbb208_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Extended Suites Chihuahua La Juventud Maria Montessori Lt. 1 y 2 #4102 Chihuahua CHIH $49 nightly $59 total Feb 23 - Feb 24 Total with taxes and fees Stay at this aparthotel in Chihuahua. Enjoy free parking, a 24-hour health club, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. ... 8.6/10 Excellent! (1,222 reviews) comfortable beds Reviewed on Feb 9, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F23%2F2026&endDate=2%2F24%2F2026&selected=28409866&PinnedHotelID=28409866&HadPinnedHotel=true®ionId=553248635640632170) [See all 75 properties in Santa Isabel](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=2%2F13%2F2026&endDate=2%2F14%2F2026®ionId=553248635640632170) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Extended Suites Chihuahua La Juventud](https://images.trvl-media.com/lodging/29000000/28410000/28409900/28409866/05dbb208_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Extended Suites Chihuahua La Juventud Maria Montessori Lt. 1 y 2 #4102 Chihuahua CHIH Stay at this aparthotel in Chihuahua. Enjoy free parking, a 24-hour health club, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. ... 8.6/10 Excellent! (1,222 reviews) comfortable beds Reviewed on Feb 9, 2026 [](https://expedia.com/Chihuahua-Hotels-Extended-Suites-Chihuahua-La-Juventud.h28409866.Hotel-Information) ![Amplio Departamento privado. Ideal para familia.](https://images.trvl-media.com/lodging/28000000/27340000/27333000/27332956/cf57bbaf_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Amplio Departamento privado. Ideal para familia. Chihuahua Chih. Stay at this apartment in Chihuahua. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions El Encino Trailhead and Tres Presas Metropolitan ... Muy limpio Todo esta muy bien Reviewed on Aug 9, 2023 [](https://expedia.com/Chihuahua-Hotels-Amplio-Departamento-Privado-Ideal-Para-Familia.h27332956.Hotel-Information) ![Mauro Pena Valdes](https://images.trvl-media.com/lodging/102000000/101520000/101512600/101512533/4751b7e1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Mauro Pena Valdes Chihuahua Chih. Stay at this vacation home in Chihuahua. Enjoy laundry facilities, cable/satellite TV service, and an in-room coffeemaker. Popular attractions Fashion Mall and ... 6/10 (2 reviews) El no es responsable cuando llegue ahí nunca contestó las llamadas o mensaje tuve que irme a un hotel y mis vacaciones se hecharon a perder Reviewed on Aug 20, 2025 [](https://expedia.com/Chihuahua-Hotels-Mauro-Pena-Valdes.h101512533.Hotel-Information) [See all properties in Santa Isabel](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=553248635640632170&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Santa Isabel hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640632170&startDate=2026-02-12&endDate=2026-02-13)[Feb 12 - Feb 13](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640632170&startDate=2026-02-12&endDate=2026-02-13) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640632170&startDate=2026-02-13&endDate=2026-02-14)[Feb 13 - Feb 14](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640632170&startDate=2026-02-13&endDate=2026-02-14) [This weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640632170&startDate=2%2F13%2F2026&endDate=2%2F15%2F2026)[Feb 13 - Feb 15](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640632170&startDate=2%2F13%2F2026&endDate=2%2F15%2F2026) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640632170&startDate=2%2F20%2F2026&endDate=2%2F22%2F2026)[Feb 20 - Feb 22](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640632170&startDate=2%2F20%2F2026&endDate=2%2F22%2F2026) ## Cities near Santa Isabel ![Cathedral of Our Lady of Guadalupe](https://images.trvl-media.com/place/6320157/40d2c3ae-a585-4949-9eb3-d7645b2cd3cb.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Chihuahua ![Mexico, Mexico City, Monument to Cuauhtemoc near Zocal and financial center.](https://images.trvl-media.com/place/6253837/b21478f4-e4a6-4f51-8bac-54aacb99926a.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Cuauhtemoc ## Explore a world of travel with Expedia - Lodging - Packages - Cars - [Gran Morelos Hotels ](https://www.expedia.com/Gran-Morelos-Hotels.d553248635640642922.Travel-Guide-Hotels) - [Dr. Belisario Domínguez Hotels ](https://www.expedia.com/Dr-Belisario-Dominguez-Hotels.d553248635640660826.Travel-Guide-Hotels) - [Gay friendly Hotels in Haciendas del Valle I Etapa ](https://www.expedia.com/Haciendas-Del-Valle-I-Etapa-Chihuahua-Hotels-LGBT-Welcoming-Hotel.0-n553248635976400442-0-tLGBTWelcomingHotel.Travel-Guide-Filter-Hotels) - [Basilica de Chihuahua ](https://www.expedia.com/Basilica-De-Chihuahua-Chihuahua.d553248621532630603.Vacation-Attraction) - [Fashion Mall ](https://www.expedia.com/Fashion-Mall-Chihuahua.d6130042.Vacation-Attraction) - [Car rentals near Gran Morelos ](https://www.expedia.com/Car-Rentals-In-Gran-Morelos.d553248635640642922.Car-Rental-Guide) - [Car rentals near Dr. Belisario Domínguez ](https://www.expedia.com/Car-Rentals-In-Dr-Belisario-Dominguez.d553248635640660826.Car-Rental-Guide) - [Car rentals near Fashion Mall ](https://www.expedia.com/Car-Rentals-In-Fashion-Mall.d6130042.Car-Rental-Guide) - Cities near Santa Isabel - Places of interest [Chihuahua](https://expedia.com/Chihuahua.dx939)[Cuauhtemoc](https://expedia.com/Cuauhtemoc.dx6253837)[Satevó](https://expedia.com/Satevo.dx553248635640656462) - [District 1 - Shopping Mall ](https://expedia.com/District-1-Shopping-Mall-Chihuahua.d553248635998002047.Vacation-Attraction) - [Cathedral of Chihuahua ](https://expedia.com/Cathedral-Of-Chihuahua-Centro-Historico.d6115624.Vacation-Attraction) - [Fashion Mall ](https://expedia.com/Fashion-Mall-Chihuahua.d6130042.Vacation-Attraction) - [Autonomous University of Chihuahua ](https://expedia.com/Autonomous-University-Of-Chihuahua-Chihuahua.d6275814.Vacation-Attraction) - [Medical Star Hospital ](https://expedia.com/Medical-Star-Hospital-Chihuahua.d553248635976809349.Vacation-Attraction) - [Distrito Uno ](https://expedia.com/Distrito-Uno-Chihuahua.d736168664163729408.Vacation-Attraction) - [Hospital Angeles Chihuahua ](https://expedia.com/Hospital-Angeles-Chihuahua-Chihuahua.d736169689999413248.Vacation-Attraction) - [Plaza de Armas ](https://expedia.com/Plaza-De-Armas-Centro-Historico.d6320153.Vacation-Attraction) - [Cumbres de Majalca National Park ](https://expedia.com/Cumbres-De-Majalca-National-Park-Chihuahua.d6115625.Vacation-Attraction) - [St Barths Spa ](https://expedia.com/St-Barths-Spa-Chihuahua.d553248635998002048.Vacation-Attraction) - [Quinta Gameros Cultural Center ](https://expedia.com/Quinta-Gameros-Cultural-Center-Centro-Historico.d6275797.Vacation-Attraction) - [Historical Museum of the Mexican Revolution ](https://expedia.com/Historical-Museum-Of-The-Mexican-Revolution-Chihuahua.d6275810.Vacation-Attraction) - [Basilica de Chihuahua ](https://expedia.com/Basilica-De-Chihuahua-Chihuahua.d553248621532630603.Vacation-Attraction) - [Government Palace ](https://expedia.com/Government-Palace-Centro-Historico.d553248621532977318.Vacation-Attraction) - [Casa Chihuahua Museum ](https://expedia.com/Casa-Chihuahua-Museum-Centro-Historico.d6275791.Vacation-Attraction) - [Museo Casa de Villa ](https://expedia.com/Museo-Casa-De-Villa-Chihuahua.d553248621532976938.Vacation-Attraction) - [City Hall of Chihuahua ](https://expedia.com/City-Hall-Of-Chihuahua-Centro-Historico.d553248621551385186.Vacation-Attraction) - [Casa Juarez Museum ](https://expedia.com/Casa-Juarez-Museum-Centro-Historico.d6275820.Vacation-Attraction) - [Museum of the Republican Loyalty House Juarez ](https://expedia.com/Museum-Of-The-Republican-Loyalty-House-Juarez-Centro-Historico.d6320145.Vacation-Attraction) - [Semilla Museum of Science and Technology ](https://expedia.com/Semilla-Museum-Of-Science-And-Technology-Chihuahua.d6275823.Vacation-Attraction) - [Plaza Saucito ](https://expedia.com/Plaza-Saucito-Chihuahua.d736176736508624896.Vacation-Attraction) - [Medical Place ](https://expedia.com/Medical-Place-Chihuahua.d736174521971961856.Vacation-Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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