Santee River Dam on Lake Marion, South Carolina, Aerial drone view of electric power lines

Santee Vacation Rentals

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Check prices for these dates

In two weeks
Aug 21 - Aug 23
In two months
Oct 2 - Oct 4
In three months
Oct 30 - Nov 1
In four months
Nov 27 - Nov 29

Our top choices for Santee vacation rentals

Terrace/patio

1. LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks
Santee
8.8 out of 10, Excellent, (6 reviews)
"Beautiful listing beautiful views. Host very responsive and was quick to take care of any issues. You will enjoy your stay. "
United States
A P C.
$420 nightly
The price is $466
Aug 11 - Aug 12
Total with taxes and fees
LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks
Property grounds

2. Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
Santee
10.0 out of 10, Exceptional, (15 reviews)
"Annual golf trip with old friends. Perfect accommodations & location. Hope to stay again"
United States
Greg M.
$460 nightly
The price is $511
Aug 11 - Aug 12
Total with taxes and fees
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
Panoramic Tent | Lake view

3. Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (97 reviews)
"If you’re looking for a quiet and peaceful getaway this place was great! The lake is beautiful and you can kayak or just sit out by the water and relax. The cute ducks in the property were my favorite. Would definitely go back again."
United States
Amber
$77 nightly
The price is $85
Aug 13 - Aug 14
Total with taxes and fees
Bells Marina & Resort
Dining

4. Country living lake style near Santee

Country living lake style near Santee
Summerton
10.0 out of 10, Exceptional, (46 reviews)
"Yes parking was very easy and everything is very convenient for what we did while we stayed this place is in a perfect location "
United States
James R.
$192 nightly
The price is $213
Aug 8 - Aug 9
Total with taxes and fees
Country living lake style near Santee
Interior

5. Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301

Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
Bowman
9.8 out of 10, Exceptional, (34 reviews)
"The place was excellent. The bed was really nice and comfortable. I'd definitely stay again."
United States
Joseph
$147 nightly
The price is $163
Aug 8 - Aug 9
Total with taxes and fees
Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
Outdoor dining

6. Cozy Camping Cabin on Lake Marion near Congaree Nat Park

Cozy Camping Cabin on Lake Marion near Congaree Nat Park
Rimini
8.4 out of 10, Very Good, (16 reviews)
"Great place to stay. "
United States
Scott J.
$120 nightly
The price is $133
Aug 6 - Aug 7
Total with taxes and fees
Cozy Camping Cabin on Lake Marion near Congaree Nat Park
Terrace/patio

7. Cabin at the lake in Rimini, SC

Cabin at the lake in Rimini, SC
Rimini
7.4 out of 10, Good, (8 reviews)
"Great view, excellent communication with the owners, relaxing, peaceful. "
United States
Christie
$128 nightly
The price is $142
Aug 6 - Aug 7
Total with taxes and fees
Cabin at the lake in Rimini, SC
Property grounds

8. Pet friendly country cottage with large fenced-in yard & horses on property

Pet friendly country cottage with large fenced-in yard & horses on property
Holly Hill
10.0 out of 10, Exceptional, (155 reviews)
"Nice place, friendly hosts!"
United States
Dan R.
$185 nightly
The price is $205
Aug 6 - Aug 7
Total with taxes and fees
Pet friendly country cottage with large fenced-in yard & horses on property
Smart TV, books

9. Modern apartment overlooking historic downtown Elloree, SC.

Modern apartment overlooking historic downtown Elloree, SC.
Elloree
$177 nightly
The price is $196
Aug 6 - Aug 7
Total with taxes and fees
Modern apartment overlooking historic downtown Elloree, SC.
Private kitchen

10. Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston

Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston
Holly Hill
10.0 out of 10, Exceptional, (14 reviews)
"Great stay!"
United States
Hayden S.
$145 nightly
The price is $161
Aug 7 - Aug 8
Total with taxes and fees
Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston
Exterior detail

11. 2 Full Beds Non-Smoking

2 Full Beds Non-Smoking
St George, SC
10.0 out of 10, Exceptional, (10 reviews)
$84 nightly
The price is $93
Aug 25 - Aug 26
Total with taxes and fees
2 Full Beds Non-Smoking
Beach

12. Country Resting Spot just off I95. 12 miles west on hwy 6.

Country Resting Spot just off I95. 12 miles west on hwy 6.
Elloree
9.4 out of 10, Exceptional, (23 reviews)
"Amazing "
United States
Fisher R.
$167 nightly
The price is $185
Aug 19 - Aug 20
Total with taxes and fees
Country Resting Spot just off I95. 12 miles west on hwy 6.
TV, table tennis

13. Turtle Cove - Lake Living on Lake Marion

Turtle Cove - Lake Living on Lake Marion
Summerton
10.0 out of 10, Exceptional, (1 review)
"Great quiet and cozy home with a nice backyard and porch with the easy water access by dock. Really enjoyed our stay."
United States
Judith H.
$389 nightly
The price is $442
Aug 6 - Aug 7
Total with taxes and fees
Turtle Cove - Lake Living on Lake Marion
Coffee/tea maker, fridge, microwave, oven

14. Hobbs Haven at Lake Marion

Hobbs Haven at Lake Marion
Summerton
9.4 out of 10, Exceptional, (13 reviews)
"Great location and host."
United States
Jay M.
$341 nightly
The price is $379
Aug 9 - Aug 10
Total with taxes and fees
Hobbs Haven at Lake Marion
Microwave, oven, stovetop, dishwasher

15. 3-bedroom house in fabulous Summerton next to lake

3-bedroom house in fabulous Summerton next to lake
Summerton
10.0 out of 10, Exceptional, (2 reviews)
"We really enjoyed our stay at this lovely home! It was the perfect lake getaway for our family and exactly what we were looking for for a relaxing weekend. The home was comfortable, well-kept, and had everything we needed. We made some wonderful memories and would definitely recommend it to others looking for a peaceful place to stay."
United States
Casey L.
3-bedroom house in fabulous Summerton next to lake
Exterior detail

16. Orangeburg SC|Queen Bed

Orangeburg SC|Queen Bed
Orangeburg SC
10.0 out of 10, Exceptional, (51 reviews)
"Decent spot for a restful night. Sleep was solid and check in was fast."
United States
Anonymous traveler
$89 nightly
The price is $98
Aug 6 - Aug 7
Total with taxes and fees
Orangeburg SC|Queen Bed
Exterior detail

17. The Tee Vee Cove is the place to be located near great golfing, fishing and food

The Tee Vee Cove is the place to be located near great golfing, fishing and food
Elloree
9.4 out of 10, Exceptional, (3 reviews)
"Came to area for hiking. Plenty of spots and the location was great. Wonderful experience and enjoyed the outside patio in the evenings."
United States
Debra S.
$225 nightly
The price is $250
Sep 4 - Sep 5
Total with taxes and fees
The Tee Vee Cove is the place to be located near great golfing, fishing and food
Microwave, oven, stovetop, dishwasher

18. Beautiful brick home w/ large porch and 3 bedrooms

Beautiful brick home w/ large porch and 3 bedrooms
Bowman
9.2 out of 10, Wonderful, (5 reviews)
"A great home and very peaceful!! The host is very friendly and very easy to work with. I recommend this home for a stay 100 percent!!We plan on staying there again when we are in the area, such a great value!!"
United States
Troy K.
$253 nightly
The price is $280
Aug 10 - Aug 11
Total with taxes and fees
Beautiful brick home w/ large porch and 3 bedrooms
Miscellaneous

19. Lakeside Glamping Tent with Kayaks & Spacious Deck in Eutaw Springs, South Carolina

Lakeside Glamping Tent with Kayaks & Spacious Deck in Eutaw Springs, South Carolina
Eutaw Springs
$183 nightly
The price is $203
Aug 9 - Aug 10
Total with taxes and fees
Lakeside Glamping Tent with Kayaks & Spacious Deck in Eutaw Springs, South Carolina
Living area

20. Blue Bird Manor 3-bedroom house located in the heart of Orangeburg

Blue Bird Manor 3-bedroom house located in the heart of Orangeburg
Orangeburg
8.6 out of 10, Excellent, (4 reviews)
"Absolutely loved it such an adorable home a host had a a quick response as well as tips! Very happy with our stay"
United States
jessie j.
$195 nightly
The price is $220
Aug 7 - Aug 8
Total with taxes and fees
Blue Bird Manor 3-bedroom house located in the heart of Orangeburg
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Best Western Plus Santee Inn

Best Western Plus Santee Inn

10/10 Excellent
"Breakfast was good, staff very helpful."
Bonnie 1-night trip
Posted 2 hours ago
Best Western Plus Santee Inn

Find out more about Santee

Everything you need to know about Santee vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santee vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santee vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santee vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santee. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santee in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $85 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santee rentals

At Expedia, we put the best Santee vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santee rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santee vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santee. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Santee?

Yes, we offer vacation rentals near the most popular points of interest in Santee, or you can select a more remote option if you'd like a relaxing place to stay. Tourists appreciate the top-notch restaurants and coffeehouses in Santee. Make sure you have time to check out the golf courses and lake views during your trip.

What are some of the best vacation home rentals in Santee?

Patio + Pool Table: Lake Marion Getaway: Visitors like this Santee vacation home rental. It is located on a lake and has a patio, a garden, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. Another good choice for your trip to Santee is Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!.

How many vacation rentals are there in Santee?

Expedia has 7 vacation rentals for your stay in Santee.

What can I see and do in Santee?

While you're exploring the area, Lake Marion and Santee National Wildlife Refuge are a couple of picturesque spots to get outside and enjoy nature. Santee Cooper Country Club and Santee State Park are other places to visit while you're in town.

What are vacation rentals like in Santee?

Vacation rentals are private accommodations you can book for several days or more in Santee. Vacation rentals feature amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a great choice for family gatherings.