Santee River Dam on Lake Marion, South Carolina, Aerial drone view of electric power lines

Santee Vacation Rentals

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Check prices for these dates

In two weeks
Jul 3 - Jul 5
In two months
Aug 14 - Aug 16
In three months
Sep 11 - Sep 13
In four months
Oct 9 - Oct 11

Our top choices for Santee vacation rentals

Terrace/patio

LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks
Santee
8.4 out of 10, Very Good, (5 reviews)
$441 nightly
The price is $490
Jul 6 - Jul 7
Total with taxes and fees
LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks
Smart TV, offices

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Santee
10.0 out of 10, Exceptional, (43 reviews)
"Thanks again Mike for a great stay! All the best, Paul"
United States
Paul V.
$381 nightly
The price is $423
Jun 29 - Jun 30
Total with taxes and fees
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Property grounds

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
Santee
10.0 out of 10, Exceptional, (15 reviews)
"Annual golf trip with old friends. Perfect accommodations & location. Hope to stay again"
United States
Greg M.
$463 nightly
The price is $514
Jun 28 - Jun 29
Total with taxes and fees
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
Dining

Country living lake style near Santee

Country living lake style near Santee
Summerton
10.0 out of 10, Exceptional, (46 reviews)
"Clean, private, well maintained. Adequate parking for boaters. Excellent location for lake bound vacationers. Host very responsive."
United States
Jeffrey
$191 nightly
The price is $212
Jun 21 - Jun 22
Total with taxes and fees
Country living lake style near Santee
Fridge, microwave, oven, stovetop

Hobbs Haven at Lake Marion

Hobbs Haven at Lake Marion
Summerton
9.4 out of 10, Exceptional, (13 reviews)
$303 nightly
The price is $336
Jun 22 - Jun 23
Total with taxes and fees
Hobbs Haven at Lake Marion
Panoramic Tent | Lake view

Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (93 reviews)
"Super quaint, quiet, nice little get away."
United States
Karen
$89 nightly
The price is $98
Jun 28 - Jun 29
Total with taxes and fees
Bells Marina & Resort
Property grounds

Pet friendly country cottage with large fenced-in yard & horses on property

Pet friendly country cottage with large fenced-in yard & horses on property
Holly Hill
10.0 out of 10, Exceptional, (147 reviews)
"Nice place, friendly hosts!"
United States
Dan R.
$186 nightly
The price is $206
Jun 22 - Jun 23
Total with taxes and fees
Pet friendly country cottage with large fenced-in yard & horses on property
Interior

Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301

Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
Bowman
9.8 out of 10, Exceptional, (33 reviews)
"Will stay again."
United States
Robert B.
$147 nightly
The price is $163
Jun 22 - Jun 23
Total with taxes and fees
Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
Outdoor dining

Cozy Camping Cabin on Lake Marion near Congaree Nat Park

Cozy Camping Cabin on Lake Marion near Congaree Nat Park
Rimini
8.4 out of 10, Very Good, (16 reviews)
"Great place to stay. "
United States
Scott J.
$120 nightly
The price is $133
Jun 21 - Jun 22
Total with taxes and fees
Cozy Camping Cabin on Lake Marion near Congaree Nat Park
TV, table tennis

Turtle Cove - Lake Living on Lake Marion

Turtle Cove - Lake Living on Lake Marion
Summerton
$381 nightly
The price is $433
Jun 25 - Jun 26
Total with taxes and fees
Turtle Cove - Lake Living on Lake Marion
Exterior

Tiny Home Retreat with Lake Views & Private Patio in Eutaw Springs, South Carolina

Tiny Home Retreat with Lake Views & Private Patio in Eutaw Springs, South Carolina
Eutaw Springs
$191 nightly
The price is $212
Jun 21 - Jun 22
Total with taxes and fees
Tiny Home Retreat with Lake Views & Private Patio in Eutaw Springs, South Carolina
Private kitchen

Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston

Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston
Holly Hill
10.0 out of 10, Exceptional, (13 reviews)
"Great stay!"
United States
Hayden S.
$145 nightly
The price is $161
Jul 7 - Jul 8
Total with taxes and fees
Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston
TV, fireplace

Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8

Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8
Summerton
$480 nightly
The price is $533
Jun 21 - Jun 22
Total with taxes and fees
Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8
Living area

Blue Bird Manor 3-bedroom house located in the heart of Orangeburg

Blue Bird Manor 3-bedroom house located in the heart of Orangeburg
Orangeburg
10.0 out of 10, Exceptional, (2 reviews)
"Absolutely loved it such an adorable home a host had a a quick response as well as tips! Very happy with our stay"
United States
jessie j.
$194 nightly
The price is $219
Jun 21 - Jun 22
Total with taxes and fees
Blue Bird Manor 3-bedroom house located in the heart of Orangeburg
Terrace/patio

Cabin at the lake in Rimini, SC

Cabin at the lake in Rimini, SC
Rimini
7.4 out of 10, Good, (8 reviews)
"Great view, excellent communication with the owners, relaxing, peaceful. "
United States
Christie
$128 nightly
The price is $142
Jun 22 - Jun 23
Total with taxes and fees
Cabin at the lake in Rimini, SC
Smart TV, books

Modern apartment overlooking historic downtown Elloree, SC.

Modern apartment overlooking historic downtown Elloree, SC.
Elloree
$165 nightly
The price is $183
Jun 27 - Jun 28
Total with taxes and fees
Modern apartment overlooking historic downtown Elloree, SC.
Property grounds

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
Summerton
9.6 out of 10, Exceptional, (256 reviews)
"Beautiful Lake views and personal beach. Clean rooms, comfortable beds, lots of space. Host: great communication and instructions."
United States
Yvette G.
$571 nightly
The price is $634
Jun 30 - Jul 1
Total with taxes and fees
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
Property grounds

Lakeside Glamping Tent with Kayaks & Spacious Deck in Eutaw Springs, South Carolina

Lakeside Glamping Tent with Kayaks & Spacious Deck in Eutaw Springs, South Carolina
Eutaw Springs
$180 nightly
The price is $200
Jun 23 - Jun 24
Total with taxes and fees
Lakeside Glamping Tent with Kayaks & Spacious Deck in Eutaw Springs, South Carolina
Outdoor dining

Boat House (private Cabin) - Boat House (Private Cabin)

Boat House (private Cabin) - Boat House (Private Cabin)
Eutawville
10.0 out of 10, Exceptional, (1 review)
"This was a 1-night stop over for us, on the way to Florida. Unfortunately, we only had saltwater poles, or we would have loved to try our luck at fishing the lake. Fish were popping the water everywhere. We really enjoyed watching the gators cruising the lake as well! 1st for us. This was just a simple, no frills campground, but would love to ho back one day. Lodge was clean, and enjoyed sitting on the quiet back deck."
United States
Jaime W.
$290 nightly
The price is $322
Jul 9 - Jul 10
Total with taxes and fees
Boat House (private Cabin) - Boat House (Private Cabin)
Outdoor dining

Luxury 4-Bedroom Lake Marion Retreat w/ Rooftop Deck & Spacious Outdoor Living

Luxury 4-Bedroom Lake Marion Retreat w/ Rooftop Deck & Spacious Outdoor Living
Manning
10.0 out of 10, Exceptional, (1 review)
"My friends and I took a weekend trip to this lake house and had an amazing time. The property was clean and beautiful, the host was very attentive and communicative, and it was overall an amazing stay. We will definitely booked this property again when we are in the area. Highly recommend !"
United States
Nadjma S.
$525 nightly
The price is $583
Jul 14 - Jul 15
Total with taxes and fees
Luxury 4-Bedroom Lake Marion Retreat w/ Rooftop Deck & Spacious Outdoor Living
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Best Western Plus Santee Inn

Best Western Plus Santee Inn

8/10 Good
"Shower was weird- alternately freezing to boiling without touching the dials, even though water pressure remained the same. Not all outlets were in working order. Late night check in was efficient but without friendliness or basic hospitality skills. The housekeeping staff was delightful to chat with in the morning. Room was perfectly clean and organized. No excessive noise or draftiness. Overall a pleasant stay."
Adrienne 1-night trip
Posted 20 hours ago
Best Western Plus Santee Inn

Find out more about Santee

Everything you need to know about Santee vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santee vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santee vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santee vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santee. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santee in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $98 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santee rentals

At Expedia, we put the best Santee vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santee rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santee vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santee. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Santee?

Yes, we offer vacation rentals near the most popular points of interest in Santee, or you can select a more remote option if you'd like a relaxing place to stay. Tourists appreciate the top-notch restaurants and coffeehouses in Santee. Make sure you have time to check out the golf courses and lake views during your trip.

What are some of the best vacation home rentals in Santee?

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!: Visitors like this Santee vacation home rental. It is located on a lake and has a patio, a selection of games, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Another good choice for your trip to Santee is Patio + Pool Table: Lake Marion Getaway.

How many vacation rentals are there in Santee?

Expedia has 7 vacation rentals for your stay in Santee.

What can I see and do in Santee?

While you're exploring the area, Lake Marion and Taw Caw Creek are a couple of picturesque spots to get outside and enjoy nature. Santee Cooper Country Club and Santee National Golf Club are other places to visit while you're in town.

What are vacation rentals like in Santee?

Vacation rentals are private accommodations you can book for several days or more in Santee. Vacation rentals feature amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a great choice for family gatherings.