South Central Houston, TX
Houston
Visit South Central Houston
Popular places to visit
MD Anderson Cancer Center
Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Rice University
Enjoy the collegiate vibe around Rice University, a top university in Houston. Experience the area's acclaimed art scene and great live music.
Houston Zoo
Feed a giraffe, catch a 4-D movie or cool off in the water park at this extraordinary zoo.
University of Houston
Enjoy the collegiate vibe when you visit University of Houston, during your travels in Houston. Experience the acclaimed theater scene and lively festivals in this vibrant area.
Children's Museum of Houston
You can take time to visit Children's Museum of Houston during your travels to Houston. Experience the area's entertainment choices and acclaimed theater scene.
Houston Methodist Hospital
Though Houston Methodist Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Things to do
NASA's Space Center Admission Plus Official Houston City Tour
Houston: Space Center Houston Admission Ticket
Houston: Houston Botanic Garden Entry Ticket
Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)
Houston Museum of Natural Science: Butterfly Center Ticket
South Central Houston Hotel Deals
Hilton Houston Plaza/Medical Center
We were in town for my daughter’s medical procedure so we spent most of the time at the hospital. But the room was very nice, beds were comfortable, staff was helpful. My wife and I are already talking about going back to enjoy the rest of the amenities. Overall, great place to stay.
Reviewed on Apr 29, 2026
Hotel Zaza Houston Museum District
Great location to the Metrorail to take us to the rodeo with no hassles. Also wonderful location to walk around the neighborhood/park. Beds were comfortable. However, staff in restaurant and bar were lacking. Extremely rude when we asked for coffee or latte or even an extra set of silverware :( decor ...
Reviewed on Apr 28, 2026
InterContinental Houston by IHG
Excellent Hotel! Great price and beautiful and clean , 5 star hotel
Reviewed on Apr 26, 2026
The Westin Houston Medical Center/Museum District
The staff at the restaurant was very nice and the food was very good.
Reviewed on Apr 29, 2026
Sentral Forme Houston
The check in was awesome. We got there a little early and were able to find the front easily due to the addition info provided. It made finding everything super simple. We were greeted by David and Tiffany. They were so sweet and helpful. Tiffany definitely went above and beyond helping us and showing ...
Reviewed on Apr 26, 2026
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Breakfast is incorrect or rather not what I assumed. It consisted of coffee, bagged oatmeal and small muffins.
Reviewed on Apr 29, 2026
Check South Central Houston hotel availability
Other neighborhoods around South Central Houston
Greater Third Ward
While you're in Greater Third Ward, take in top sights like Barbara Jordan & Mickey Leland Archives or Fertitta Center, and hop on the metro to see more the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
Midtown
Characterized by a vibrant nightlife and young residents, this central Houston neighborhood boasts Ensemble Theatre, the largest African-American theater company in the US, and various parks like Midtown Park and Elizabeth Baldwin Park. Easily accessible via METRORail Red Line.
East Downtown Houston
Get to know East Downtown Houston and its many features like its restaurants and live music. You might want to explore sights like Shell Energy Stadium and Giant Beatles Statues, and you can jump on the metro at Leeland/Third Ward Station or EaDo/Stadium Station to get around the city.
Museum District
Known for its ample dining options and fascinating museums, there's plenty to explore in Museum District. You can visit top attractions like Children's Museum of Houston and Houston Natural Science Museum, and jump on the metro at Museum District Station or Hermann Park/Rice U Station to see more of the city.
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.
Downtown Houston
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
South Central Houston, TX
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- Visit Houston
- Texas Southern University
- Visit Downtown Houston
- Visit Museum District
- Buffalo Soldiers National Museum
- Visit Riverside Terrace
- Houston Vacations
- Visit Midtown
- Children's Museum of Houston
- Holocaust Museum Houston
- Houston Zoo
- Museum District Vacations
- Carl Lewis International Track and Field Complex
- Hermann Park
- Ensemble Theatre
- Houston Natural Science Museum
- Houston Museum of Fine Arts
- Miller Outdoor Theater
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