South Central Houston, TX
Houston
Visit South Central Houston
Stay near popular South Central Houston attractions
Things to do
Houston: Space Center Houston Admission Ticket
$30
per adult
92% of travellers recommend
Houston Museum of Natural Science: Butterfly Center Ticket
$15
per adult
100% of travellers recommend
Houston: Houston Botanic Garden Entry Ticket
$12
per adult
74% of travellers recommend
Houston: Guided City Tour by an Open-Top Double Decker Bus
$40
per adult
98% of travellers recommend
South Central Houston Hotel Deals
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
$88 nightly
The price is $103 total per night from Nov 6 to Nov 7
$103 total
Nov 6 - Nov 7
Total with taxes and fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our ...
8.6/10 Excellent! (2,223 reviews)
"Great place to stay. This place was hands down top of the line. And that bed was omg so comfy"
Reviewed on Oct 26, 2026
Hotel Zaza Houston Museum District
5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
$283 nightly
The price is $329 total per night from Nov 27 to Nov 28
$329 total
Nov 27 - Nov 28
Total with taxes and fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,010 reviews)
"It seemed that from front desk to the servers at the banquet.. to the server at the breakfast …. All had an attitude and were rather unhelpful and rude…. The valet guys were great … always respectful"
Reviewed on Oct 25, 2026
The Westin Houston Medical Center/Museum District
1709 DRYDEN ROAD Houston TX
$183 nightly
The price is $212 total per night from Nov 8 to Nov 9
$212 total
Nov 8 - Nov 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
InterContinental Houston by IHG
6750 Main St Houston TX
$178 nightly
The price is $208 total per night from Nov 22 to Nov 23
$208 total
Nov 22 - Nov 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
Extended Stay America Suites Houston Med Ctr Braeswood Bl
1301 Braeswood Blvd Houston TX
$77 nightly
The price is $90 total per night from Nov 2 to Nov 3
$90 total
Nov 2 - Nov 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6.2/10 (1,006 reviews)
"Room was not in the best shape, shower had black mold and ceeling was peeling off, bed was dirty, couch had tears on it.... staff was friendly though, won't be staying here though needs serious remodeling"
Reviewed on Oct 26, 2026
DoubleTree by Hilton Houston Medical Center Hotel & Suites
6800 Main Street Houston TX
$114 nightly
The price is $133 total per night from Nov 22 to Nov 23
$133 total
Nov 22 - Nov 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (715 reviews)
"The staff was very friendly and the hotel was clean. The property itself did have a bit of an issue with an unwell unhoused population."
Reviewed on Oct 26, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check South Central Houston hotel availability
Where to stay in South Central Houston
Find the best South Central Houston areas and neighborhoods for the activities you enjoy most. Learn more about South Central Houston
Learn more about South Central Houston
Downtown Houston
Known for its abundant dining options and live music, there's plenty to explore in Downtown Houston. Top attractions like Daikin Park and Toyota Center are major draws, and you can catch the metro at Central Station Main or Main Street Square Station to see more of the city.
The Galleria
Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.
Texas Medical Center
Well-liked for its restaurants, museums, and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo is a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Montrose
Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
Photo by George Zimzores
Open Photo by George Zimzores
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.
South Central Houston, TX
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- Visit Greenway Plaza-Upper Kirby
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- Where to stay in Houston
- Visit Museum District
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- Houston Vacations
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