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A park with a paved path lined by large trees.

Find all hotels by Best Western in St. George, SC from $104

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    Check prices for these dates, December 15 – 16, 2026

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    Our top choices for St. George Best Western

    1. Best Western Of Walterboro

    A modern living room with large windows, a ceiling fan, and a mix of seating including a sofa, armchairs, and ottomans.

    Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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    Top St. George Hotel Reviews

    Fairfield Inn & Suites by Marriott Santee

    A patio area with wicker furniture, a stone fire pit, and outdoor seating.

    Hampton Inn Santee-I-95

    A Hampton Inn hotel at night with a well-lit facade and a parking lot in the foreground.

    Tru By Hilton Santee

    A modern lobby with a blue sofa, teal chairs, and a wooden table.

    Hampton Inn & Suites Walterboro

    A hotel lobby with a long reception desk, multiple seating areas, and a television mounted on the wall.

    Best Western Plus Santee Inn

    A hotel entrance with a sign reading "Best Western PLISS."

    Holiday Inn Exp Walterboro by IHG

    A modern breakfast area with a wooden counter, a digital clock, and a beverage dispenser.

    Comfort Inn & Suites Walterboro I-95

    A hotel room with two beds, a desk, a chair, and a large window with curtains.

    Bells Marina & Resort

    Front of property

    Microtel Inn & Suites by Wyndham Walterboro

    A Microtel Inn Suites by Wyndham with a parking lot and a red car parked in front.

    Baymont by Wyndham Santee

    A hotel room with a large bed, a nightstand, a lamp, a wooden headboard, and a cityscape painting on the wall.

    Holiday Inn Santee by IHG

    A Holiday Inn hotel with a covered entrance, multiple windows, and a landscaped front yard.

    Red Roof Inn St George, SC

    A hotel lobby with a large sliding glass door, a reception desk, a seating area with red chairs, and a stone accent wall.

    Comfort Inn & Suites Santee

    A room with a black console table displaying coffee and tea options, a large window, and a sliding glass door leading to a dining area with red chairs.

    Peach Tree Inn

    A dining area with a Christmas tree, wooden cabinets, and a coffee machine.

    Moonnight inn.

    A room with a tiled floor, a white door, and a window with blinds. There are two round tables with chairs.

    Best Western Of Walterboro

    A modern living room with large windows, a ceiling fan, and a mix of seating including a sofa, armchairs, and ottomans.

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