Title: TOP 10 Hotels in St. Joseph, TN (from $67) - COMPETITIVE PRICES | Expedia.com [St. Joseph Travel Guide](https://expedia.com/St-Joseph.dx553248634999377534)[Vacation Rentals in St. Joseph](https://expedia.com/St-Joseph-Vacation-Rentals.d553248634999377534.Travel-Guide-VacationRentals)[Car Rentals in St. Joseph](https://expedia.com/Car-Rentals-In-St-Joseph.d553248634999377534.Car-Rental-Guide)[St. Joseph Vacation Packages](https://expedia.com/St-Joseph.d553248634999377534.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in St. Joseph Cabin [](https://www.expedia.com/Hotel-Search?destination=St.+Joseph%2C+Tennessee%2C+United+States+of+America®ionId=553248634999377534&latLong=35.031402%2C-87.505171&adults=2&startDate=2026-04-16&d1=2026-04-16&endDate=2026-04-18&d2=2026-04-18&lodging=CABIN) Pool [](https://www.expedia.com/Hotel-Search?destination=St.+Joseph%2C+Tennessee%2C+United+States+of+America®ionId=553248634999377534&latLong=35.031402%2C-87.505171&adults=2&startDate=2026-04-16&d1=2026-04-16&endDate=2026-04-18&d2=2026-04-18&amenities=POOL) Family friendly [](https://www.expedia.com/Hotel-Search?destination=St.+Joseph%2C+Tennessee%2C+United+States+of+America®ionId=553248634999377534&latLong=35.031402%2C-87.505171&adults=2&startDate=2026-04-16&d1=2026-04-16&endDate=2026-04-18&d2=2026-04-18&travelerType=family_friendly) Pet friendly [](https://www.expedia.com/Hotel-Search?destination=St.+Joseph%2C+Tennessee%2C+United+States+of+America®ionId=553248634999377534&latLong=35.031402%2C-87.505171&adults=2&startDate=2026-04-16&d1=2026-04-16&endDate=2026-04-18&d2=2026-04-18&amenities=PETS) Hot tub [](https://www.expedia.com/Hotel-Search?destination=St.+Joseph%2C+Tennessee%2C+United+States+of+America®ionId=553248634999377534&latLong=35.031402%2C-87.505171&adults=2&startDate=2026-04-16&d1=2026-04-16&endDate=2026-04-18&d2=2026-04-18&amenities=HOT_TUB) Apart­ment [](https://www.expedia.com/Hotel-Search?destination=St.+Joseph%2C+Tennessee%2C+United+States+of+America®ionId=553248634999377534&latLong=35.031402%2C-87.505171&adults=2&startDate=2026-04-16&d1=2026-04-16&endDate=2026-04-18&d2=2026-04-18&lodging=APARTMENT) ## Check prices for these dates Tonight [Apr 2 - Apr 3](https://www.expedia.com/Hotel-Search?regionId=553248634999377534&startDate=2026-04-02&endDate=2026-04-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 3 - Apr 4](https://www.expedia.com/Hotel-Search?regionId=553248634999377534&startDate=2026-04-03&endDate=2026-04-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=553248634999377534&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=553248634999377534&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for St. Joseph hotels ![Reception](https://images.trvl-media.com/lodging/2000000/1550000/1549300/1549240/7112cb8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Tuscumbia Muscle Shoals [](https://www.expedia.com/Florence-Hotels-The-ColdWater-Inn.h1549240.Hotel-Information) Tuscumbia 8.8/10 Excellent (735 reviews) "Great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sue Ellen $107 nightly $119 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-The-ColdWater-Inn.h1549240.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1200000/1192100/1192023/73b55f8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1200000/1192100/1192023/12d01464.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Separate tub and shower, designer toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/2000000/1200000/1192100/1192023/9e8460ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/2000000/1200000/1192100/1192023/750824be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Renaissance Shoals Resort & Spa [](https://www.expedia.com/Florence-Hotels-Marriott-Shoals-Hotel-And-Spa.h1192023.Hotel-Information) East Florence 9.2/10 Wonderful (773 reviews) "Clean room nice place." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) cheryl $269 nightly $309 total May 3 - May 4 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Marriott-Shoals-Hotel-And-Spa.h1192023.Hotel-Information) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/29000000/28810000/28803300/28803264/a6f0c75f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/29000000/28810000/28803300/28803264/b939e5ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/29000000/28810000/28803300/28803264/aa5e52fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/29000000/28810000/28803300/28803264/40546268.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Stricklin Hotel [](https://www.expedia.com/Florence-Hotels-The-Stricklin-Hotel.h28803264.Hotel-Information) Florence 9.0/10 Wonderful (847 reviews) "Bed was so comfy! Beautiful hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dwan $197 nightly $218 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-The-Stricklin-Hotel.h28803264.Hotel-Information) ![Iron/ironing board, free cribs/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/12100/12032/0700fc64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12100/12032/fd1eea60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free cribs/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/12100/12032/b47d0b56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/12100/12032/c438edb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Muscle Shoals Florence [](https://www.expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-Muscle-Shoals-Florence.h12032.Hotel-Information) Muscle Shoals 8.6/10 Excellent (1,001 reviews) "Breakfast was good and the staff was friendly parking is great and very clean rooms. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose $71 nightly $79 total Apr 16 - Apr 17 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-Muscle-Shoals-Florence.h12032.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/8600/8599/e70761df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8600/8599/c9b1fdcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/8600/8599/2fdb7dd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/1000000/10000/8600/8599/0af48b1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clarion Inn Sheffield Muscle Shoals [](https://www.expedia.com/Florence-Hotels-Clarion-Inn-Sheffield-Muscle-Shoals.h8599.Hotel-Information) Sheffield 7.2/10 Good (991 reviews) "We really enjoyed our stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vickie $77 nightly $86 total Apr 23 - Apr 24 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Clarion-Inn-Sheffield-Muscle-Shoals.h8599.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/4000000/3170000/3160100/3160009/66e294b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/4000000/3170000/3160100/3160009/baaf2d09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/4000000/3170000/3160100/3160009/6fa7225a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3170000/3160100/3160009/f71d0716.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Florence Shoals Area [](https://www.expedia.com/Florence-Hotels-Comfort-Suites-Florence-Shoals-Area.h3160009.Hotel-Information) Florence 8.8/10 Excellent (797 reviews) "Clean environment and friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donna $109 nightly $125 total May 3 - May 4 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Comfort-Suites-Florence-Shoals-Area.h3160009.Hotel-Information) ![Premium bedding, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/4000000/3180000/3173300/3173212/1d744d5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 11:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/4000000/3180000/3173300/3173212/5f470956.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3180000/3173300/3173212/d1efc2ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3180000/3173300/3173212/1c5240b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals [](https://www.expedia.com/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-TuscumbiaMuscle-Shoals.h3173212.Hotel-Information) Tuscumbia 8.2/10 Very Good (1,000 reviews) "Nice location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael $63 nightly $70 total Apr 16 - Apr 17 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-TuscumbiaMuscle-Shoals.h3173212.Hotel-Information) ![Standard Room, 2 Double Beds | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/15000000/14930000/14927700/14927603/ed4c9190.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite, 1 King Bed | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/15000000/14930000/14927700/14927603/9f4f6d9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/15000000/14930000/14927700/14927603/c9fa6ba0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/15000000/14930000/14927700/14927603/0236df74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Richland Inn Lawrenceburg [](https://www.expedia.com/Pulaski-Hotels-Richland-Inn-Lawrenceburg.h14927603.Hotel-Information) Lawrenceburg 8.4/10 Very Good (382 reviews) "The rooms and bathroom were tidy and neat. Nice value for the price. I’d happily stay here again if in the area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Warren $82 nightly $96 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/Pulaski-Hotels-Richland-Inn-Lawrenceburg.h14927603.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/3000000/2980000/2976500/2976409/1fbbd61b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2980000/2976500/2976409/b5eb58b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2980000/2976500/2976409/9c01203e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2980000/2976500/2976409/b98329bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG [](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-FLORENCE-NORTHEAST.h2976409.Hotel-Information) Florence 9.0/10 Wonderful (612 reviews) "Clean room and breakfast was good" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Josh M. $130 nightly $150 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-FLORENCE-NORTHEAST.h2976409.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/4000000/3560000/3557700/3557696/8518663c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3560000/3557700/3557696/5d39cbbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/4000000/3560000/3557700/3557696/0305e1fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3560000/3557700/3557696/8facec08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn Florence Marriott [](https://www.expedia.com/Florence-Hotels-Residence-Inn-Florence-Marriott.h3557696.Hotel-Information) East Florence 9.0/10 Wonderful (337 reviews) "Room was clean and parking was plentiful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charlotte $112 nightly $129 total May 3 - May 4 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Residence-Inn-Florence-Marriott.h3557696.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17800000/17793400/17793356/ab7fab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/18000000/17800000/17793400/17793356/497a6dca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (with Sofabed) | Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/18000000/17800000/17793400/17793356/7857762f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17800000/17793400/17793356/b80a739c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites [](https://www.expedia.com/Florence-Hotels-Best-Western-Plus-Tuscumbia-Muscle-Shoals-Hotel-And-Suites.h17793356.Hotel-Information) Tuscumbia 9.2/10 Wonderful (641 reviews) "The staff was excellent! The front desk clerk even remembered my name. Super nice hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carol $149 nightly $163 total Apr 4 - Apr 5 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Best-Western-Plus-Tuscumbia-Muscle-Shoals-Hotel-And-Suites.h17793356.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/30000000/29360000/29352000/29351966/54b7ba3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/30000000/29360000/29352000/29351966/6c04ccd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, 1 King Bed, Balcony | Premium bedding, pillowtop beds, minibar, in-room safe](https://images.trvl-media.com/lodging/30000000/29360000/29352000/29351966/0e8f4ac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, 1 King Bed, Balcony | Premium bedding, pillowtop beds, minibar, in-room safe](https://images.trvl-media.com/lodging/30000000/29360000/29352000/29351966/d0ac2f40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### GunRunner Boutique Hotel [](https://www.expedia.com/Florence-Hotels-GunRunner-Boutique-Hotel.h29351966.Hotel-Information) Florence 9.4/10 Exceptional (192 reviews) "Awesome boutique hotel in every regard." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark $199 nightly $221 total Apr 27 - Apr 28 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-GunRunner-Boutique-Hotel.h29351966.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/1000000/70000/67100/67060/c13613f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/70000/67100/67060/e3eee8cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/67100/67060/ebcf39be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/67100/67060/d69651c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Florence/Muscle Shoals [](https://www.expedia.com/Florence-Hotels-Baymont-By-Wyndham-FlorenceMuscle-Shoals.h67060.Hotel-Information) Florence 7.2/10 Good (917 reviews) "Nice clean room with all the essential amenities and conveniently located to everything as far as restaurants and shopping " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Damien $74 nightly $85 total May 1 - May 2 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Baymont-By-Wyndham-FlorenceMuscle-Shoals.h67060.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/58000000/57790000/57787900/57787812/w3837h2560x3y0-4dcf1fc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/58000000/57790000/57787900/57787812/w3836h2560x4y0-89638dee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/58000000/57790000/57787900/57787812/w3837h2557x3y3-474a11bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Accessible, Bathtub (Larger Room;with Sofabed) | Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/58000000/57790000/57787900/57787812/w3837h2556x3y4-4a153d1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Lawrenceburg [](https://www.expedia.com/Pulaski-Hotels-Best-Western-Plus-Lawrenceburg.h57787812.Hotel-Information) Lawrenceburg 9.6/10 Exceptional (322 reviews) "Nice hotel. Staff was wonderful. Breakfast was great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott $140 nightly $164 total Apr 4 - Apr 5 Total with taxes and fees [](https://www.expedia.com/Pulaski-Hotels-Best-Western-Plus-Lawrenceburg.h57787812.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1820000/1818400/1818371/9d66b3ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1820000/1818400/1818371/38023656.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Two Queen Beds | Living area | 32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/2000000/1820000/1818400/1818371/96f72727.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1820000/1818400/1818371/bb01de46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence-Downtown [](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Downtown.h1818371.Hotel-Information) Florence 9.2/10 Wonderful (714 reviews) "Great staff, pool was heated. Good location plenty of parking." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ward $121 nightly $134 total Apr 26 - Apr 27 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Downtown.h1818371.Hotel-Information) ![Snack bar](https://images.trvl-media.com/lodging/1000000/130000/120300/120232/5bb7a1a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Accessible, Non Smoking | Iron/ironing board, free wired internet, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/130000/120300/120232/6766b4fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/130000/120300/120232/b0b6f4af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/130000/120300/120232/4b77b742.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Florence Midtown near University of North Alabama [](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Florence-Midtown.h120232.Hotel-Information) Florence 9.0/10 Wonderful (550 reviews) "Quiet, and clean staff was courteous and attendant" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cynthia $88 nightly $101 total May 3 - May 4 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Hampton-Inn-Florence-Midtown.h120232.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/88000000/87820000/87812900/87812888/42e9e8b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite Single Bed (1 King) | Bathroom | Soap, shampoo, toilet paper](https://images.trvl-media.com/lodging/88000000/87820000/87812900/87812888/2c97bd27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Bed (2 Queen) | Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/88000000/87820000/87812900/87812888/ba8c0806.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/88000000/87820000/87812900/87812888/b9720e2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Budget Inn & Suites [](https://www.expedia.com/Florence-Hotels-Budget-Inn.h87812888.Hotel-Information) East Florence 7.4/10 Good (154 reviews) "Clean room and price friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aaron $61 nightly $67 total Apr 8 - Apr 9 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Budget-Inn.h87812888.Hotel-Information) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990270/8384096c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990270/c0b6ef4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990270/9a484ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/2000000/1990300/1990270/da2e415f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Tuscumbia - Muscle Shoals [](https://www.expedia.com/Florence-Hotels-Comfort-Inn-Suites-Tuscumbia-Muscle-Shoals.h1990270.Hotel-Information) Tuscumbia 8.2/10 Very Good (260 reviews) "Room was clean, and safe. The air worked well. The staff was around a 3/5\. Maybe they need a raise. There were plenty of shops and food near by. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Valerie $125 nightly $139 total May 2 - May 3 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Comfort-Inn-Suites-Tuscumbia-Muscle-Shoals.h1990270.Hotel-Information) ![Room, 1 King Bed, Non Smoking | Iron/ironing board, rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/13000000/12280000/12276200/12276120/108122a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking | Bathroom | Combined shower/tub, towels, soap, shampoo](https://images.trvl-media.com/lodging/13000000/12280000/12276200/12276120/810cf29b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/13000000/12280000/12276200/12276120/e2933700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/13000000/12280000/12276200/12276120/53961881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Economy Inn [](https://www.expedia.com/Florence-Hotels-Economy-Inn.h12276120.Hotel-Information) Rogersville 7.8/10 Good (152 reviews) "Clean and affordable..Great friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveler $72 nightly $80 total Apr 4 - Apr 5 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Economy-Inn.h12276120.Hotel-Information) ![Superior Room, 1 King Bed, Smoking, Jetted Tub | Room amenity](https://images.trvl-media.com/lodging/1000000/50000/40300/40293/018967fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/50000/40300/40293/a5acad41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40300/40293/f01738a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/50000/40300/40293/a820578b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Muscle Shoals [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Muscle-Shoals.h40293.Hotel-Information) Muscle Shoals 6.8/10 (308 reviews) "The room was spotless and smelled so clean. First time in a motel in years. It was so cute owners" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael $75 nightly $83 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn-Muscle-Shoals.h40293.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-17&endDate=2026-04-18®ionId=553248634999377534&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSt-Joseph-Hotels.d553248634999377534.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSt-Joseph-Hotels.d553248634999377534.Travel-Guide-Hotels) ## Top St. Joseph Hotel Reviews ![Comfort Suites Florence Shoals Area](https://images.trvl-media.com/lodging/4000000/3170000/3160100/3160009/66e294b6_y.jpg) ### Comfort Suites Florence Shoals Area 2/10 Terrible "The first room the refrigerator was broke and the second room the shower didn’t work" [](https://expedia.com/Florence-Hotels-Comfort-Suites-Florence-Shoals-Area.h3160009.Hotel-Information) ![Renaissance Shoals Resort & Spa](https://images.trvl-media.com/lodging/2000000/1200000/1192100/1192023/73b55f8d_y.jpg) ### Renaissance Shoals Resort & Spa 10/10 Excellent "I love this hotel, great pool area and pet friendly. " [](https://expedia.com/Florence-Hotels-Marriott-Shoals-Hotel-And-Spa.h1192023.Hotel-Information) ![Hampton Inn & Suites Florence-Downtown](https://images.trvl-media.com/lodging/2000000/1820000/1818400/1818371/9d66b3ae_y.jpg) ### Hampton Inn & Suites Florence-Downtown 10/10 Excellent "Clean rooms " [](https://expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Downtown.h1818371.Hotel-Information) ![The Stricklin Hotel](https://images.trvl-media.com/lodging/29000000/28810000/28803300/28803264/a6f0c75f_y.jpg) ### The Stricklin Hotel 10/10 Excellent "Personal attention. Very clean and good location." [](https://expedia.com/Florence-Hotels-The-Stricklin-Hotel.h28803264.Hotel-Information) ![Richland Inn Lawrenceburg](https://images.trvl-media.com/lodging/15000000/14930000/14927700/14927603/ed4c9190_y.jpg) ### Richland Inn Lawrenceburg 10/10 Excellent "Excellent location. Many restaurants in the area as well as a Kroger and Walmart under 1/2 mile. Very quiet location, easy parking. Super clean. Breakfast is Southern. Biscuits and gravy, eggs, sausage patties, links, and hash browns. And also waffles. Comfortable bed and great pillows! Lots of Cable channels. Nice staff. I will stay here in a heartbeat the next time Im in the area." [](https://expedia.com/Pulaski-Hotels-Richland-Inn-Lawrenceburg.h14927603.Hotel-Information) ![Quality Inn Lawrenceburg](https://images.trvl-media.com/lodging/3000000/2210000/2206400/2206339/93cbd598_y.jpg) ### Quality Inn Lawrenceburg 8/10 Good "Room was clean and updated. The door to the bathroom couldn't close, and the TV wouldn't work." [](https://expedia.com/Lawrenceburg-Hotels-Quality-Inn.h2206339.Hotel-Information) ![Lagniappe in Florence ](https://images.trvl-media.com/lodging/102000000/101330000/101323800/101323766/2e8c792f_y.jpg) ### Lagniappe in Florence 10/10 Excellent "A beautifully remodeled home! It had everything we needed to be comfortable. Great location and wonderful kitchen appliances and grill! We will book this home again when visiting our daughter. " [](https://expedia.com/Florence-Hotels-Lagniappe-In-Florence.h101323766.Hotel-Information) ![Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG](https://images.trvl-media.com/lodging/3000000/2980000/2976500/2976409/1fbbd61b_y.jpg) ### Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG 2/10 Terrible "Poor customer service Rude general manager" [](https://expedia.com/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-FLORENCE-NORTHEAST.h2976409.Hotel-Information) ![Residence Inn Florence Marriott](https://images.trvl-media.com/lodging/4000000/3560000/3557700/3557696/8518663c_y.jpg) ### Residence Inn Florence Marriott 10/10 Excellent "Room was clean and parking was plentiful. " [](https://expedia.com/Florence-Hotels-Residence-Inn-Florence-Marriott.h3557696.Hotel-Information) ## More cheap stays in St. Joseph ![Baymont by Wyndham Florence/Muscle Shoals](https://images.trvl-media.com/lodging/1000000/70000/67100/67060/d69651c5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Florence/Muscle Shoals 115 Ana Drive Florence AL $74 nightly $85 total May 1 - May 2 Total with taxes and fees 7.2/10 Good! (917 reviews) [](https://expedia.com/Florence-Hotels-Baymont-By-Wyndham-FlorenceMuscle-Shoals.h67060.Hotel-Information) ![Richland Inn Lawrenceburg](https://images.trvl-media.com/lodging/15000000/14930000/14927700/14927603/ed4c9190_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Richland Inn Lawrenceburg 2125 North Locust Avenue Lawrenceburg TN $82 nightly $96 total Apr 13 - Apr 14 Total with taxes and fees 8.4/10 Very Good! (382 reviews) [](https://expedia.com/Pulaski-Hotels-Richland-Inn-Lawrenceburg.h14927603.Hotel-Information) ![Comfort Suites Florence Shoals Area](https://images.trvl-media.com/lodging/4000000/3170000/3160100/3160009/66e294b6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Suites Florence Shoals Area 140 Matthew Paul Ct Florence AL $109 nightly $125 total May 3 - May 4 Total with taxes and fees 8.8/10 Excellent! (797 reviews) [](https://expedia.com/Florence-Hotels-Comfort-Suites-Florence-Shoals-Area.h3160009.Hotel-Information) ![Hampton Inn & Suites Florence-Downtown](https://images.trvl-media.com/lodging/2000000/1820000/1818400/1818371/9d66b3ae_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn & Suites Florence-Downtown 505 S Court St Florence AL $121 nightly $134 total Apr 26 - Apr 27 Total with taxes and fees 9.2/10 Wonderful! (714 reviews) [](https://expedia.com/Florence-Hotels-Hampton-Inn-Suites-Florence-Downtown.h1818371.Hotel-Information) ![Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG](https://images.trvl-media.com/lodging/3000000/2980000/2976500/2976409/1fbbd61b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG 180 Etta Gray Street Florence AL $130 nightly $150 total Apr 12 - Apr 13 Total with taxes and fees 9/10 Wonderful! (612 reviews) [](https://expedia.com/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-FLORENCE-NORTHEAST.h2976409.Hotel-Information) ![Best Western Plus Lawrenceburg](https://images.trvl-media.com/lodging/58000000/57790000/57787900/57787812/w3837h2560x3y0-4dcf1fc2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Plus Lawrenceburg One Western Way Lawrenceburg TN $140 nightly $164 total Apr 4 - Apr 5 Total with taxes and fees 9.6/10 Exceptional! (322 reviews) [](https://expedia.com/Pulaski-Hotels-Best-Western-Plus-Lawrenceburg.h57787812.Hotel-Information) ## Hotels in St. Joseph with star-rating ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 27 properties [](https://expedia.com/3Star-St-Joseph-Hotels.s30-0-d553248634999377534.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 16 properties [](https://expedia.com/2Star-St-Joseph-Hotels.s20-0-d553248634999377534.Travel-Guide-Filter-Hotels) ## Frequently asked questions ### What is the best area to stay in St Joseph? > The town center of St. Joseph is compact and offers a pleasant, small-town setting. Main Street is where you'll find the majority of the town's establishments, including a few local eateries and shops. The layout is straightforward, making it easy to navigate on foot. This area is ideal for solo travelers or couples looking for a relaxed stay with easy access to the town's core. > > > For those interested in exploring the natural beauty of the surrounding area, staying near the town center provides a good starting point for day trips. ### When is the best time to go to St Joseph? > During spring, you'll experience mild temperatures, typically ranging from the low 60s to high 70s Fahrenheit, making it comfortable for outdoor activities. The rolling hills and natural landscapes surrounding St. Joseph are particularly beautiful as wildflowers bloom. It's an excellent time for couples or solo travelers who enjoy scenic drives and exploring nature trails without the intensity of summer heat. > > > Fall provides similarly agreeable temperatures, usually from the 50s to 70s Fahrenheit, with less humidity. The foliage displays vibrant colors, offering picturesque views. This season is great for families looking for comfortable weather for outdoor excursions like visiting local farms or enjoying walks in the countryside. The cooler evenings are also ideal for relaxing outdoors. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a St. Joseph hotel booking with Expedia? > \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo. ### How much is the nightly rate at a St. Joseph hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Hotels near Loretto Sports Complex ](https://www.expedia.com/Loretto-Sports-Complex-Hotels.0-l648656334383034368-0.Travel-Guide-Filter-Hotels) - [Iron City Hotels ](https://www.expedia.com/Iron-City-Hotels.d553248634999283737.Travel-Guide-Hotels) - [Loretto Hotels ](https://www.expedia.com/Loretto-Hotels.d553248634999031070.Travel-Guide-Hotels) - [Westpoint Hotels ](https://www.expedia.com/Westpoint-Hotels.d553248635975849121.Travel-Guide-Hotels) - [Collinwood Hotels ](https://www.expedia.com/Collinwood-Hotels.d3000353512.Travel-Guide-Hotels) - [Cabin Rentals in Collinwood ](https://www.expedia.com/Collinwood-Cabins.d3000353512-aaCabins.Travel-Guide-Accommodation) - [Motels in Collinwood ](https://www.expedia.com/Collinwood-Motels.d3000353512-aaMotels.Travel-Guide-Accommodation) - 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