Find 4 Star Hotels in Cross Keys, MO from $122
Upfront pricing
Our total price for your stay includes taxes and fees
Treat yourself
Save 10% or more on over 100,000 hotels worldwide with Member Prices
Be picky
Search almost a million properties worldwide
Check availability on Cross Keys 4 Star Hotels
Compare Cross Keys 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
8.4 out of 10, Very Good, (3887)
$107 nightly
The price is $126
Aug 22 - Aug 23
Total includes taxes and fees
Moonrise Hotel
Moonrise Hotel
9.0 out of 10, Wonderful, (1821)
$161 nightly
The price is $191
Aug 24 - Aug 25
Total includes taxes and fees
21C Museum Hotel St Louis
21C Museum Hotel St Louis
9.0 out of 10, Wonderful, (1269)
$165 nightly
The price is $193
Jul 27 - Jul 28
Total includes taxes and fees
St. Louis Union Station Hotel, Curio Collection by Hilton
St. Louis Union Station Hotel, Curio Collection by Hilton
8.4 out of 10, Very Good, (1005)
$191 nightly
The price is $227
Aug 3 - Aug 4
Total includes taxes and fees
DoubleTree by Hilton St. Louis Airport
DoubleTree by Hilton St. Louis Airport
7.8 out of 10, Good, (776)
$114 nightly
The price is $134
Aug 7 - Aug 8
Total includes taxes and fees
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
8.6 out of 10, Excellent, (1016)
$103 nightly
The price is $122
Aug 18 - Aug 19
Total includes taxes and fees
Renaissance St. Louis Airport Hotel
Renaissance St. Louis Airport Hotel
8.4 out of 10, Very Good, (1021)
$111 nightly
The price is $130
Aug 8 - Aug 9
Total includes taxes and fees
Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
8.4 out of 10, Very Good, (1018)
$183 nightly
The price is $214
Aug 10 - Aug 11
Total includes taxes and fees
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 5-star hotels
Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Cross Keys.
Four Seasons Hotel St Louis
999 North Second Street, St. Louis, MO
$425 nightly
The price is $497 total per night from Jul 31 to Aug 1
$497 total
Jul 31 - Aug 1
Total includes taxes and fees
9.4/10 Exceptional! (1,005 reviews)
Still don't see what you're looking for?
See all properties in Cross Keys.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Cross Keys
Head to St. Louis Zoo and St. Louis Union Station—just two of the popular sights around Cross Keys.
Top Cross Keys Hotel Reviews
Hyatt Regency St. Louis at The Arch
10/10 Excellent
Find out more about Cross Keys
Find out more about Cross Keys
Cross Keys Four Star Hotel Information
When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Cross Keys, St. Louis are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Cross Keys 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.
Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Cross Keys. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Cross Keys, St. Louis, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.
Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Cross Keys hotels offer everything your heart desires.
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- 4 Star Hotels in Castle Point
- Cabin Rentals in Castle Point
- Castle Point Hotels
- Condo Rentals in Castle Point
- 5 Star Hotels in Spanish Lake
- Spanish Lake Hotels
- Motels in Spanish Lake
- Pet-friendly Hotels in Spanish Lake
- Drury Inn & Suites Hotels in Spanish Lake
- B&B in Spanish Lake
- Moline Acres Hotels
- St. Louis Hotels
- Bellefontaine Neighbors Hotels
- Hotels near Old Chain of Rocks Bridge
- 5 Star Hotels in Jennings
- 4 Star Hotels in Jennings
- 4 Star Hotels in Ferguson
- 5 Star Hotels in Ferguson
- Jennings Hotels
- B&B in Jennings
- Guest Houses in Jennings
- Apartments in Jennings
- Extended Stay America Hotels in Jennings
- Motels in Jennings
- 5 Star Hotels in Florissant
- 4 Star Hotels in Florissant
- Ferguson Hotels
- Motel 6 Hotels in Ferguson
- B&B in Ferguson
- Motels in Ferguson
- La Quinta Inn & Suites Hotels in Ferguson
- Best Western Hotels in Ferguson
- Florissant Hotels
- Cheap Hotels in Florissant
- Motels in Florissant
- B&B in Florissant
- Motel 6 Hotels in Florissant
- Pet-friendly Hotels in Florissant
- Cabin Rentals in Florissant
- Marriott Hotels & Resorts in Florissant
- Hotels with a Pool in Florissant
- Hotels with Bars in Florissant
- Extended Stay America Hotels in Florissant
- Vacation Homes in Florissant
- Romantic Hotels in Florissant
- Luxury Hotels in Florissant
- Condo Rentals in Florissant
- Cottages in Florissant
- Hotels & Resorts for Couples in Florissant
- La Quinta Inn & Suites Hotels in Florissant
- Hotels with an Outdoor Pool in Florissant
- Oakwood Hotels in Florissant
- Family Hotels in Florissant
- Villas in Florissant
- 3 Star Hotels in Berkeley
- 5 Star Hotels in Kinloch
- Norwood Court Hotels
- Hotels near Berkeley
- Car rentals near Castle Point
- Car rentals near Black Jack
- Car rentals near Spanish Lake
- Car rentals near Bellefontaine Neighbors
- Car rentals near Glasgow Village
- Car rentals near Dellwood
- Car rentals near Calverton Park
- Car rentals near Jennings
- Car rentals near Ferguson
- Enterprise Rental Cars in Ferguson
- Hertz Rental Cars in Ferguson
- Car rentals near Country Club Hills
- Car rentals near Florissant
- Avis Rental Cars in Florissant
- Enterprise Rental Cars in Florissant
- Dollar Rent A Car Rental Cars in Florissant
- Thrifty Car Rental Rental Cars in Florissant
- Luxury Car Rentals in Florissant
- Car rental St. Louis Airport (STL)
- Car rentals near Norwood Court
- Hertz Rental Cars in Berkeley
- Car rentals near Berkeley