--- title: "The Best 5 Star Hotels in Key West, FL from $330 | Expedia" description: "Save on luxurious 5★ hotels in Key West: Browse our selection of popular hotels & resorts in the region, providing top-notch amenities. Book an outstanding vacation with Expedia." canonical: "https://www.expedia.com/5Star-Key-West-Hotels.s50-0-d1187.Travel-Guide-Filter-Hotels" language: en-US market: US currency: USD prices_as_of: 2026-11-14T03:02:51Z --- Plan your trip - [Key West Travel Guide](https://www.expedia.com/Key-West.dx1187) - [Hotels in Key West](https://www.expedia.com/Key-West-Hotels.d1187.Travel-Guide-Hotels) - [Flights to Key West](https://www.expedia.com/Cheap-Flights-To-Key-West.d1187.Travel-Guide-Flights) - [Things to do in Key West](https://www.expedia.com/Things-To-Do-In-Key-West.d1187.Travel-Guide-Activities) - [Car Rentals in Key West](https://www.expedia.com/Car-Rentals-In-Key-West.d1187.Car-Rental-Guide) - [Key West Vacation Packages](https://www.expedia.com/Key-West.d1187.Destination-Travel-Guides) - [Vacation Rentals in Key West](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals) # Find 5 Star Hotels in Key West, FL from $330 ![A sign for the Key West Museum of Art & History at the Custom House.](https://images.trvl-media.com/place/1187/0ede9218-a8aa-41bb-aa96-f51aff5931f7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ### Upfront pricing Our total price for your stay includes taxes and fees ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) ### Be picky Search almost a million properties worldwide ## Check prices for these dates [Check prices for these dates, December 14 – 15, 2026](https://www.expedia.com/Hotel-Search?regionId=1187&startDate=2026-12-14&endDate=2026-12-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&star=50) [View in a map](https://www.expedia.com/Hotel-Search?regionId=1187&stayLength=1&daysInFuture=30&pwaOverlay=map) ## Find out more about Key West ### Key West Five Star Hotel Information If you’re searching for the celebrity treatment, the 5 star hotels in Key West are your dreams come true. From sprawling resorts to fancy hot spots, theseKey West 5 star hotels immerse each traveler in the most elite experience money can buy. Want to unwind with a VIP-worthy spa treatment? These hotels have the leisure you're looking for. Interested in sampling world-class cuisine? The on-site restaurants at the 5 stars hotels in Key West, Florida, let you do just that. You’ll even be able to book a room (or perhaps a penthouse?) at first-rate hotels near the region’s can’t-miss sights and most bustling shopping centers. Plus, many globe-trotters who visit Key West five star hotels find incredible rates and deep discounts thanks to Expedia, so you can score a deal without sacrificing an ounce of quality. Everything you could possibly want (and a few things you didn’t know you needed): That’s what you’ll receive when you stay at Key West 5 star hotels. ## Frequently Asked Questions ### What are the best 5-star hotels in Key West? Step into a world of luxury at [Casa Marina Key West, Curio Collection by Hilton](https://www.expedia.com/Key-West-Hotels-Casa-Marina-Key-West.h12346.Hotel-Information). This is one of the most highly rated 5-star hotels in Key West according to Expedia guest reviews. From its premium amenities and services to its prime location, you can count on an exceptional guest experience. ### How much does it cost to stay in a 5-star hotel in Key West? The amount you pay for a 5-star hotel in Key West depends on factors such as when you plan to travel and the length of your vacation. An insider tip for landing an awesome deal? Use our pricing filters to check out all of the available accommodations for your preferred dates. - Search for the lowest price per night from $330 ### What makes a hotel 5 stars in Key West? In Key West, a hotel must offer a certain level of upscale features to earn a 5-star rating. These may include on-site gyms, saunas and spas, gourmet restaurants, complimentary luxury toiletries, premium bedding and more. What also sets 5-star hotels apart is their extraordinary standard of service. You can look forward to things like nightly turn-down services, in-room massages and concierge services. Some may even offer additional touches like welcome gifts. ### Are there any 5-star all-inclusive resorts in Key West? Find a luxury getaway that includes your lodging, meals, bar and entertainment in Key West with our filter tool. Search for resorts rated 5 stars and select the "All inclusive" filter. Double-check what's included in the purchase price. That way, you'll be ready to maximize the many perks on offer when you arrive. ### What are the top 5-star spa hotels in Key West? Book a massage and feel all your worries instantly melt away at [Casa Marina Key West, Curio Collection by Hilton](https://www.expedia.com/Key-West-Hotels-Casa-Marina-Key-West.h12346.Hotel-Information). This 5-star spa retreat in Key West provides a variety of rejuvenating therapies and amenities that pamper the body, mind and soul. ### Are there any 5-star vacation rentals in Key West? There are no 5-star vacation rentals in Key West on our site, but there are some other top-rated properties worth looking into. Search through our [vacation rentals in Key West](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals) to discover the perfect place for your getaway. ### Are there any 5-star hotels in downtown Key West? Check out [Casa Marina Key West, Curio Collection by Hilton](https://www.expedia.com/Key-West-Hotels-Casa-Marina-Key-West.h12346.Hotel-Information). This 5-star hotel is perfect if you want to experience Key West's downtown scene. ### What are the top 5-star hotels near Key West Intl. Airport (EYW)? Whether you're arriving in the evening or have an early flight out of Key West, it's worth looking at [Casa Marina Key West, Curio Collection by Hilton](https://www.expedia.com/Key-West-Hotels-Casa-Marina-Key-West.h12346.Hotel-Information). This 5-star hotel is conveniently located about 4 mi west of Key West Intl. 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