Find All Southern Minnesota Hotels
Upfront pricing
Our total price for your stay includes taxes and fees
Treat yourself
Save 10% or more on over 100,000 hotels worldwide with Member Prices
Be picky
Search almost a million properties worldwide
Find All Southern Minnesota Hotels
We have found 1164 Southern Minnesota Hotels
- AmericInn by Wyndham Rochester Near Mayo Clinic
- Kahler Grand Hotel
- Med City Inn & Suites - Mayo Clinic Area
- Spark by Hilton Rochester South
- Hyatt House Rochester/Mayo Clinic Area
- Kahler Inn and Suites - Mayo Clinic Area
- Aspen Select
- La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
- Hotel Indigo Rochester – Mayo Clinic Area by IHG
- St James Hotel, a Historic Hotel of America
- EVEN Hotel Rochester - Mayo Clinic Area by IHG
- Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
- SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
- Country Inn & Suites Rochester South Mayo Clinic
- Econo Lodge Mayo Clinic Area
- Motel 6 Mankato, MN
- Express Suites Riverport Inn & Suites
- GrandStay Cannon Falls
- Country Inn & Suites by Radisson, Rochester, MN
- AmericInn by Wyndham Mankato Event Center
- Quality Inn near Medical Center
- Hilton Rochester Mayo Clinic Area
- Super 8 by Wyndham Rochester Mayo Clinic Area
- Hampton Inn & Suites Rochester-North
- Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
- Super 8 by Wyndham Winona MN
- Cobblestone Hotel & Suites - Austin
- Residence Inn by Marriott Rochester Mayo Clinic Area South
- Country Inn & Suites by Radisson, Albert Lea - Austin
- Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
- AmericInn by Wyndham Rochester
- Redwood Lodge
- EverSpring Inn & Suites
- Brentwood Inn & Suites
- Hampton Inn Rochester-South
- Quality Inn & Suites
- The Plaza Hotel & Suites Winona
- Staybridge Suites Rochester - Mayo Clinic Area by IHG
- Boarders Inn & Suites by Cobblestone Hotels - Faribault
- Microtel Inn & Suites by Wyndham Mankato
- AmericInn by Wyndham Winona
- Travelodge by Wyndham Red Wing
- Super 8 by Wyndham Red Wing
- Holiday Inn Express & Suites Winona by IHG
- Baymont by Wyndham Rochester Mayo Clinic Area
- Coratel Inn & Suites By Jasper Northfield
- Quality Inn & Suites
- Days Inn by Wyndham Austin
- Days Inn by Wyndham Mankato
- Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
- Country Inn & Suites by Radisson, Red Wing, MN
- AmericInn by Wyndham Northfield
- Ramada by Wyndham Albert Lea
- AmericInn by Wyndham Lake City
- Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
- AmericInn by Wyndham Austin
- Baymont by Wyndham Owatonna
- Staybridge Suites Rochester - Commerce Dr NW by IHG
- Fairfield Inn & Suites by Marriott Winona
- Hilton Garden Inn Rochester Downtown, MN
- Home2 Suites by Hilton Rochester Mayo Clinic Area
- TownePlace Suites by Marriott Rochester Mayo Clinic Area
- Sleep Inn & Suites West-Near Medical Center
- Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
- Holiday Inn Express Rochester South - Mayo Area by IHG
- AmericInn by Wyndham Albert Lea
- Extended Stay America Suites Rochester North
- Quality Inn Owatonna Near Medical Center
- TownePlace Suites by Marriott Rochester
- AmericInn by Wyndham Worthington
- Country Inn & Suites by Radisson, Mankato Hotel and Conference Center, MN
- Americas Best Value Inn Zumbrota
- AmericInn by Wyndham St. Peter
- Motel 6 Rochester, MN
- Aspen Suites
- Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
- Best Western Plus New Ulm
- Coratel Inn & Suites by Jasper Mankato
- Nichols Inn of Red Wing
- Harmony Inn
- Best Western Plus Albert Lea I-90/I-35 Hotel
- Econo Lodge Luverne I-90
- MainStay Suites Rochester South Mayo Clinic
- Super 8 by Wyndham Jackson MN
- Super 8 by Wyndham Marshall MN
- Microtel Inn & Suites by Wyndham New Ulm
- Comfort Inn Albert Lea
- Days Inn by Wyndham Faribault
- America's Stay Inn Stewartville
- Sleep Inn & Suites Marshall - University Area
- Courtyard Mankato Marriott
- Comfort Inn & Suites West - Medical Center
- Quality Inn & Suites Red Wing
- Americas Best Value Inn & Suites Spring Valley
- Super 8 by Wyndham Austin MN
- Grandstay Hotel And Suites Luverne
- Hilton Garden Inn Mankato Downtown
- AmericInn by Wyndham Jackson
Let Expedia take you to the best Hotels in Southern Minnesota. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.