$46 Car Rental Seneca, SC

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Top Car Deals in Seneca

* Price found within the past 6 days. Click for updated prices.

Economy

Mitsubishi Mirage
  • 4 people
  • Unlimited mileage
Greenville, South Carolina, USA
Mitsubishi Mirage

$48

includes taxes & fees
$29 per day
found 6 hours ago
Economy Mitsubishi Mirage

Compact

Nissan Versa
  • 5 people
  • Unlimited mileage
Greenville, South Carolina, USA
Nissan Versa

$50

includes taxes & fees
$31 per day
found 6 hours ago
Compact Nissan Versa

Special

Wild Card Compact or larger if available
  • 5 people
  • Unlimited mileage
Greer, South Carolina, USA
Wild Card Compact or larger if available

$46

includes taxes & fees
$31 per day
found 7 hours ago
Special Wild Card Compact or larger if available

Midsize

Toyota Corolla
  • 5 people
  • Unlimited mileage
Greenville, South Carolina, USA
Toyota Corolla

$51

includes taxes & fees
$32 per day
found 6 hours ago
Midsize Toyota Corolla

Fullsize

Nissan Altima
  • 5 people
  • Unlimited mileage
Greenville, South Carolina, USA
Nissan Altima

$53

includes taxes & fees
$33 per day
found 6 hours ago
Fullsize Nissan Altima

Standard Special

Subaru Impreza
  • 5 people
  • Unlimited mileage
Lavonia, Georgia, USA
Subaru Impreza

$50

includes taxes & fees
$45 per day
found 2 days ago
Standard Special Subaru Impreza

Standard Elite Special

Ford Mustang Mach-E
  • 5 people
  • Unlimited mileage
Greenville, South Carolina, USA
Ford Mustang Mach-E

$66

includes taxes & fees
$47 per day
found 6 hours ago
Standard Elite Special Ford Mustang Mach-E

Premium

Nissan Maxima
  • 5 people
  • Unlimited mileage
Anderson, South Carolina, USA
Nissan Maxima

$65

includes taxes & fees
$57 per day
found 2 days ago
Premium Nissan Maxima

Mini Van

Chrysler Pacifica
  • 7 people
  • Unlimited mileage
Lavonia, Georgia, USA
Chrysler Pacifica

$66

includes taxes & fees
$60 per day
found 2 days ago
Mini Van Chrysler Pacifica

Luxury

Audi A4 Genesis G70 BMW 3 series
  • 5 people
  • Unlimited mileage
Anderson, South Carolina, USA
Audi A4  Genesis G70  BMW 3 series

$72

includes taxes & fees
$63 per day
found 2 days ago
Luxury Audi A4 Genesis G70 BMW 3 series

Premium Elite Van

Ford Transit Wagon
  • 15 people
  • Unlimited mileage
Anderson, South Carolina, USA
Ford Transit Wagon

$84

includes taxes & fees
$75 per day
found 2 days ago
Premium Elite Van Ford Transit Wagon

Fullsize Elite Special

Audi A5 Sportback
  • 5 people
  • Unlimited mileage
Greer, South Carolina, USA
Audi A5 Sportback

$140

includes taxes & fees
$107 per day
found 6 hours ago
Fullsize Elite Special Audi A5 Sportback

Luxury Elite SUV

Range Rover Sport BMW X7 Mercedes GLS
  • 5 people
  • Unlimited mileage
Lavonia, Georgia, USA
Range Rover Sport  BMW X7  Mercedes GLS

$125

includes taxes & fees
$115 per day
found 2 days ago
Luxury Elite SUV Range Rover Sport BMW X7 Mercedes GLS

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Lowest prices found within the past 6 hours. Prices and availability subject to change. Additional terms may apply.

What you need to know for your Seneca car rental

Reasons to book a car rental in and around Seneca

Renting a car in Seneca provides the freedom and flexibility to explore the area at your own pace. With a car, you can easily visit attractions like Highpointe Lower Field, an urban park perfect for outdoor experiences, right within Seneca. For those seeking scenic views and romantic outings, Lake Keowee is just 9 miles away, offering beautiful beach areas and outdoor activities. Additionally, the historic Memorial Stadium is only 6 miles from Seneca, making it convenient for sports and cultural experiences. A rental car also opens the door to nearby cities like Clemson, located 7 miles away, where you can experience more attractions such as the South Carolina Botanical Gardens. Exploring the charming areas of Keowee and Normandy Shores is also hassle-free with a rental, allowing you to visit locations like South Cove Park and enjoy the natural beauty of the region. Whether you are traveling with family, friends, or looking for a romantic getaway, having a car makes it easy to manage luggage and create flexible travel plans as you discover all that Seneca and its surroundings have to offer.

Most popular car rentals in Seneca

  • Compact SUV: This car type is a top choice for travelers in Seneca, accommodating up to 5 passengers and providing space for 3 medium suitcases. The compact SUV is perfect for solo adventurers, couples, or families looking to explore the area. Its versatility makes it ideal for navigating through both busy streets and scenic routes with ease.
  • Midsize: Another popular option, the midsize car comfortably seats 5 travelers while offering ample room for up to 3 large suitcases. This vehicle is particularly suitable for couples or families who wish to travel comfortably without sacrificing space. Whether you're planning a weekend getaway or a longer trip, the midsize option provides a great balance of comfort and practicality.
  • Fullsize: If you're traveling with family or in larger groups, the fullsize car is the way to go. It accommodates up to 5 travelers and can hold either 3 large suitcases or 5 medium suitcases. This spacious option ensures that everyone has room to relax and enjoy the journey, making it an excellent choice for those planning to explore the beautiful surroundings of Seneca.

Top rated car suppliers in Seneca

  • Enterprise: Enterprise is a top choice for car rentals in Seneca, boasting one rental location in the area. Travelers appreciate their excellent customer service and the flexibility of rental options. The most booked vehicles include Midsize SUVs and Fullsize cars, ideal for those looking to explore Seneca and its attractions comfortably. With a reputation for friendly staff and well-maintained vehicles, Enterprise ensures a reliable experience for all types of travelers.

Where to stay in and around Seneca

  • Clemson: Located 7 miles from Seneca, Clemson is an ideal spot for travelers seeking a blend of culture and outdoor experiences. Visitors can explore the historic college university and enjoy activities at the scenic Lake Keowee, perfect for a romantic getaway or a family outing. Key attractions include Memorial Stadium, a historic sports venue, and the South Carolina Botanical Gardens, which offers beautiful landscapes for outdoor enthusiasts. Clemson also has a variety of dining options, including wineries and restaurants.
  • Pendleton: Situated 10 miles from Seneca, Pendleton is known for its charming outdoor and romantic atmosphere. With attractions like the historic Woodburn house and Memorial Stadium, there's plenty to appreciate for culture buffs. The area is also home to scenic lakes and recreational spots, making it a great choice for nature lovers. Pendleton offers a selection of nearby dining options, including wineries and restaurants, enhancing the experience for visitors.
  • Normandy Shores: Nestled within the vicinity of Seneca, Normandy Shores is a quaint village that offers stunning outdoor scenery and romantic settings. The area features Lake Keowee, ideal for those looking to enjoy beach activities or scenic views. Notable attractions include South Cove Park, a family-friendly urban park perfect for outdoor fun. Normandy Shores is also close to historic college universities and national state parks, providing a diverse range of activities and dining options nearby.

10 tips to save on your car rental in and around Seneca

  1. Use filters to find the right car: Refine your search by selecting vehicle types and features. Whether you're in need of an SUV for extra room, a convertible for summer enjoyment, or an economy car for budget-friendliness, utilize the filters on Expedia to discover the ideal vehicle for your journey.
  2. Book in advance to help lower costs: Rental rates can vary based on demand, so it's wise to reserve your car well ahead of your trip. By booking in advance, you're more likely to secure lower rates and have better availability, especially during peak travel seasons.
  3. Consider a smaller car for savings: Smaller vehicles are typically more affordable to rent and easier to park in crowded areas. Mid-size rentals strike a good balance between cost, comfort, and fuel efficiency.
  4. Age guidelines: Drivers under 30 may encounter higher deposits or daily fees, and certain vehicle categories—such as SUVs or luxury models—might be unavailable. This policy can also apply to renters over the age of 70. Always verify age requirements before you make a reservation.
  5. Check fuel policies: Some rental agreements require a full-to-full fuel policy, meaning you must return the vehicle with a full tank to avoid extra charges. This is usually the most favorable option. Others might offer full-to-empty or prepaid fueling choices, which are acceptable as well—just remember to return the car with an empty tank in that case.
  6. Save on city and airport pickups: Picking up your rental car at airports often incurs a surcharge, but the convenience may justify the extra cost.
  7. Know your payment options: Most car rental companies only accept credit cards for payment.
  8. Understand your insurance coverage: Car rental insurance can help you avoid unexpected expenses and provides peace of mind in case something unplanned occurs during your trip. It's easy to add rental insurance when booking through Expedia.
  9. Consider unlimited mileage: If you're planning long road trips, look for rental options that offer unlimited mileage to prevent additional costs.
  10. Bring your driver's license and ID: A valid driver's license is necessary for renting a car.

Best time to rent a car in and around Seneca

The best value period to rent a car in and around Seneca is February, when prices are slightly low and demand is moderately low. Following closely, January offers similar advantages with slightly low prices and lower demand. For those looking for mid-range options, March and May present average pricing and demand. However, November tends to be the most expensive month, with slightly high prices and steady demand, while October shows similar characteristics, making it a busier time for rentals.

Finding the cheapest car rentals in Seneca

Using our Search Wizard

If the deals that are available on our page do not suit your needs, then enter Seneca into the search wizard at the top of the page. We will compare all the best deals available for your car rental in Seneca and provide you with a list of the cheapest options, with no added fees.

Renting a car in Seneca

Pay at pickup is available, so you don’t have to worry about spending your money until you arrive at your vehicle in Seneca. We partner with reliable partners that guarantee an enjoyable experience for solo travelers, couples, and families. Package your car with a flight or hotel to unlock even more savings from Expedia.

Expected prices in Seneca

Prices are subject to seasonal change depending on when you decide to arrange your car rental but right now you can book from $46.

Flexibility & Cancellation

Most car suppliers offer penalty-free cancellations, so you don’t have to worry about losing money if your plans change. To cancel your booking log into your account through the Trips portal. Click manage booking and cancel this car. If you needed to alter your booking, then you can create a new one once you have canceled.

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One Key members save 10% or more on select hotels, cars, activities and vacation rentals. Not only that, earn OneKeyCash for every dollar spent on eligible hotels, vacation rentals, flights, car rentals, and more when you book across our family of brands: Expedia, Hotels.com and VRBO. Learn more and join today.

Car classes available from Expedia in 2026

The classes of vehicles available will change depending on your chosen location.

Car Rental Information

Popular car types
SUV, Full Size, Economy
Car suppliers available
Our best deal of the day
$46
Our second best deal of the day
$48
Our third best deal of the day
$50
From the airport to your hotel
Airport Transportation
From popular domestic and international airports
Airport Car Rentals

Frequently asked questions

How much is a rental car per day in Seneca?
You'll get serious bang for your buck in Seneca, with car rental prices within the past seven days starting from as low as $46 per day.
What happens if I need to cancel my Seneca car reservation?
Scan over the cancellation policy to be certain, but almost all prepaid bookings qualify for a complete refund if you let us know more than six hours before picking up the car. There are some exemptions though. Your confirmation will have more details, or just hop onto our Customer Service Portal.
Where can I go on a road trip from Seneca?
Seneca is full of surprises, but don't limit yourself to just one place. Book a set of wheels and hit the open road to discover what else awaits in the surrounding region. We've pulled together these great options:
  • Make your way to Asheville for a fun-filled sightseeing adventure. Around 65 miles from Seneca, it has many great attractions like Biltmore Estate.
  • Next stop? Make it Columbia, which is around 120 miles away. South Carolina State House is one local highlight you really shouldn't miss.
  • Chewacla State Park is located 210 miles from Seneca and is one of the region's most breathtaking nature spots. Go for a walk around and enjoy the fresh air.
How do I find the best car rental deals in Seneca with Expedia?
Check customer ratings, choose your favorite ride and compare prices from the most popular providers. Expedia makes it easy to get the best deal on your rental wheels. Combine your Seneca car rental with hotel or flight bookings and hit the road with even bigger savings.
How old do you have to be to rent a car in Seneca?
Drivers with a valid license aged 21 and above can rent a car in Seneca. While some providers may be willing to rent to drivers younger than 21, prepare for additional fees. Find out what ages the young renter fee applies to, and associated costs, before locking in your ride. There are also restrictions on the types of cars available to young drivers. Higher age limits apply for specialty and luxury vehicles.
What do you need to rent a car in Seneca?
You'll need to present a valid driver's license and a credit card when you get to the rental counter. Prior to the pickup date, check with your rental provider whether anything else is needed. For example, you may also need to provide proof of insurance.
What is the cheapest car rental in Seneca?
The two cheapest daily rates offered in Seneca within the past seven days were $46 and $48. How's that for a great deal? These rates were available on Expedia, with a rental starting date within the next year. Prices and availability are subject to change and additional terms apply.
Can I rent a car for a month or longer in Seneca?
You can rent a vehicle for a month or even longer in Seneca, so go on and extend your hard-earned vacation! Just enter your trip dates into our long-term car rental deals page and book your ideal ride.
Where can I find a Seneca car rental if I am younger than 25?
Some Seneca companies will rent cars to drivers under 25, and others won't. Age policies differ from supplier to supplier, so you'll want to do some research. Also, find out if there are extra costs. Some outlets will apply a surcharge to young drivers between the ages of 21 and 24. Always read through the terms and conditions to avoid any surprise fees.
What insurance should I choose for my car rental in Seneca?
After perfectly planning your big trip, don't skimp on safety — choose collision protection while reserving your Seneca car rental with Expedia. There are tons of benefits to this plan, including up to $35,000 in primary coverage for collision damage, theft and vandalism. Plus, with no deductible and 24/7 emergency assistance, you can breathe a little easier if a mishap occurs.

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