Find all hotels by La Quinta Inn & Suites in Seneca, SC
Upfront pricingOur total price for your stay includes taxes and fees
Treat yourselfSave 10% or more on over 100,000 hotels worldwide with Member PricesLearn about One Key
Be pickySearch almost a million properties worldwide
Check prices for these dates
Tonight
Oct 23 - Oct 24Tomorrow
Oct 24 - Oct 25This weekend
Oct 23 - Oct 25Next weekend
Oct 30 - Nov 1
Save an average of 15% on thousands of hotels when you're signed in
Top Seneca Hotel Reviews
Lake House with Dock, Pool, and Pet Friendly. 8 Minutes from Clemson.
10/10 Excellent
"Beautiful, spacious home, perfect location. Would definitely return."
Hampton Inn & Suites Seneca-Clemson Area
10/10 Excellent
"Room was clean and staff was friendly and helpful."
Quality Inn Seneca US-123
10/10 Excellent
"Hotel was very clean and staff was very very pleasant."
Charming and Entertaining Lake House Retreat for Large Groups!
10/10 Excellent
"This is an amazing property -- that won't disappoint. I was sold on the pics but this home and surroundings are even better in person. The layout of the home, beds/baths, and all the games/amenities -- so much more than we expected. The enclosed porch was a perfect adult hangout for Mahjong while the kids played skeet-ball and video games. My nephew was even able to fish in the lake. There is nothing more that could be done to make our visit any better -- it was perfect!!. Check in and check out super easy and host was very responsive. We loved our family time together and this home was definitely a highlight. Beyond 5 stars!!"
6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.
10/10 Excellent
"Beautiful property. Close to Clemson campus. Plenty of room and felt somewhat secluded."
Fairfield Inn & Suites Seneca Clemson Univ Area
8/10 Good
"A nice variety for breakfast."
Best Western Seneca-Clemson
10/10 Excellent
"Property was very clean, well maintained, quiet, and close to our ball tournament location. Great value stay. Breakfast was really good and staff were very friendly and helpful."
Beautiful waterfront home on a private cove in Lake Keowee w/ hot tub
10/10 Excellent
"We had a wonderful stay at this beautiful lake house! The home was well stocked with everything we needed, beautifully maintained, and in a great location. It was spacious and comfortable for our family, making it the perfect place to relax and enjoy time together. We would absolutely recommend this property and would love to stay here again!"
Tru by Hilton Seneca Clemson
10/10 Excellent
"The staff were very friendly and everything was nice and clean! A great selection for breakfast!"
Explore a world of travel with Expedia
- Family Friendly in Seneca
- 3 Star Hotels in Townville
- Hotels in Central
- 5 Star Hotels in Pendleton
- Kitchen in Seneca
- 2 Star Hotels in Seneca
- Cabins in Seneca
- Budget in Seneca
- Hotels in Seneca
- 2 Star Hotels in Clemson
- OYO Rooms Hotels in Pendleton
- 4 Star Hotels in Clemson
- La Quinta Inn & Suites Hotels in Easley
- 3 Star Hotels in Clemson
- La Quinta Inn & Suites Hotels in Greenville - Spartanburg
- La Quinta Inn & Suites Hotels in Williamston
- Free Breakfast in Seneca
- Hotels near Memorial Stadium
- Beach in Seneca
- Marriott Hotels & Resorts Hotels in Salem
- Wyndham Hotels in Seneca
- 2 Star Hotels in Chickasaw Point
- 5 Star Hotels in Salem
- Hotels in Westminster
- Independent Hotels in Clemson
- Independent Hotels in Seneca
- 3 Star Hotels in Seneca
- Bedandbreakfast in Clemson
- La Quinta Inn & Suites Hotels in Belton
- 4 Star Hotels in West Union
- Pet Friendly in Seneca
- Golf in Clemson
- Privatevacationhomes in Clemson
- Hotels in Clemson
- Bar in Clemson
- Hotels in Fair Play
- La Quinta Inn & Suites Hotels in Piedmont
- 5 Star Hotels in Walhalla
- Hotels in Townville
- Hot Tub in Seneca
- Hotels in Salem
- Hotels in Keowee
- La Quinta Inn & Suites Hotels in Clemson
- Spa in Seneca
- Best Western Hotels in Seneca
- La Quinta Inn & Suites Hotels in Pelzer
- Hilton Hotels in Clemson
- Hotels in Pendleton
- America's Best Inns Hotels in Clemson
- Keowee Plantation Hotels
- Romantic in Seneca
- La Quinta Inn & Suites Hotels in Pickens
- Lake in Seneca
- 4 Star Hotels in Walhalla
- Pool in Seneca
- Indoor Pool in Clemson
- 3 Star Hotels in Westminster
- Hotels in Walhalla
- Motels in Seneca
- Flights to Pendleton
- JetBlue Airways Flushing (LGA) to Greer (GSP) flights
- Flights from Jamaica (JFK) to Seneca (CEU)
- Flights from Boston (BOS) to Seneca (CEU)
- Flights to Seneca
- Delta Air Lines Flushing (LGA) to Greer (GSP) flights
- Flights to Oconee County Regional
- Flights to Westminster
- Flights to Clemson
- Flights to Walhalla