Eastern Panama Vacation Rentals

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Check prices for these dates

In two weeks
May 1 - May 3
In two months
Jun 12 - Jun 14
In three months
Jul 10 - Jul 12
In four months
Aug 7 - Aug 9

Our top choices for Eastern Panama vacation rentals

Boating

San Blas Private Oceanfront Cabin

San Blas Private Oceanfront Cabin
2.5 star property
Narganá
$359 nightly
The price is $385
Apr 15 - Apr 16
Total with taxes and fees
San Blas Private Oceanfront Cabin
Basic Cabin, Ocean View | Beach | On the beach, white sand, free beach shuttle

Sanblastourgy

Sanblastourgy
2.0 star property
Nargana
$251 nightly
The price is $276
Apr 14 - Apr 15
Total with taxes and fees
Sanblastourgy
Exterior

Cabaña La Punta op het Strand!!

Cabaña La Punta op het Strand!!
Colón Province
$172 nightly
The price is $172
Apr 14 - Apr 15
Total with taxes and fees
Cabaña La Punta op het Strand!!
Marina

Despierta sobre el mar

Despierta sobre el mar
Garrote
6.0 out of 10, (1 review)
$100 nightly
The price is $108
Apr 15 - Apr 16
Total with taxes and fees
Despierta sobre el mar
Basic Cabin, Multiple Beds, Balcony, Sea View | Beach/ocean view

San Blas Tour Aridub

San Blas Tour Aridub
2.0 star property
Narganá
$131 nightly
The price is $144
Apr 14 - Apr 15
Total with taxes and fees
San Blas Tour Aridub
Beach nearby, beach towels

Exclusive sailboat for 2 people all inclusive in San Blas islands

Exclusive sailboat for 2 people all inclusive in San Blas islands
Guna Yala
10.0 out of 10, Exceptional, (1 review)
"Anita e Federico sono state il valore aggiunto in queste isole meravigliose. La loro disponibilita, le loro attenzioni, i sorridenti contatti di Anita con la popolazione dei Guna e la cucina superlativa di Federico hanno reso speciale la nostra vacanza che ha soddisfatto appieno le nostre aspettative. Discreta e deliziosa la presenza della gattina (la principessa di bordo) Shanu. Grazie di tutto!"
United States
Grazia B.
$605 nightly
The price is $605
Apr 15 - Apr 16
Total with taxes and fees
Exclusive sailboat for 2 people all inclusive in San Blas islands
Beach

Catamaran experience in paradise

Catamaran experience in paradise
Guna Yala Comarca
$936 nightly
The price is $936
Apr 14 - Apr 15
Total with taxes and fees
Catamaran experience in paradise
Beach

All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama

All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama
Guna Yala Comarca
$937 nightly
The price is $937
Apr 26 - Apr 27
Total with taxes and fees
All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama
Beach

Deluxe Beachfront 4-bedroom house in Colón Province

Deluxe Beachfront 4-bedroom house in Colón Province
Colón Province
$381 nightly
The price is $381
Apr 14 - Apr 15
Total with taxes and fees
Deluxe Beachfront 4-bedroom house in Colón Province
Beach

Private cabin in San Blas

Private cabin in San Blas
Panama , Betania
$302 nightly
The price is $302
Apr 14 - Apr 15
Total with taxes and fees
Private cabin in San Blas
On the beach, sun loungers, beach towels

BEAUTIFUL APARTMENT IN FRONT OF THE SEA

BEAUTIFUL APARTMENT IN FRONT OF THE SEA
Portobelo
7.0 out of 10, Good, (4 reviews)
"All of it! Gabriel is a marvelous host; absolutely above and beyond. The house is lovely, very unique, and the location, right on the water, superb. We'll be back!"
United States
Rosa M.
$180 nightly
The price is $180
Apr 15 - Apr 16
Total with taxes and fees
BEAUTIFUL APARTMENT IN FRONT OF THE SEA
Outdoor pool

Jacuzy, pool and lake at the same house.

Jacuzy, pool and lake at the same house.
Colon
6.0 out of 10, (2 reviews)
"Great. Please take care of the cat"
United States
KENNETH E.
$69 nightly
The price is $69
Apr 14 - Apr 15
Total with taxes and fees
Jacuzy, pool and lake at the same house.
Beach

Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita

Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita
Maria Chiquita
6.8 out of 10, (3 reviews)
"Well-appointed apartment, view of the ocean, big pool, fast Internet, attentive security. We had a great time here, thanks!"
United States
Will
$145 nightly
The price is $145
Apr 14 - Apr 15
Total with taxes and fees
Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita
Terrace/patio

Charming cottage with 2 separate beds and a beautiful view of the river

Charming cottage with 2 separate beds and a beautiful view of the river
Santa Rosa
10.0 out of 10, Exceptional, (1 review)
"Wir fanden die Unterkunft aufgrund der guten Wegbeschreibung sofort. Die Empfang war sehr nett. Das Haus war sehr sehr sauber und wir haben uns sehr wohl gefühlt. Alles war perfekt. Es war die sauberste/beste Unterkunft die wir bei unserer Panama Rundtour in Panama hatte. Erik und Alba alles Gute und vielen Dank."
Germany
Birgit U.
$146 nightly
The price is $146
Apr 15 - Apr 16
Total with taxes and fees
Charming cottage with 2 separate beds and a beautiful view of the river
Interior

Elegance and comfort in old town panama

Elegance and comfort in old town panama
Panamá
$90 nightly
The price is $90
Apr 14 - Apr 15
Total with taxes and fees
Elegance and comfort in old town panama
Exterior

Tranquil cabin with WiFi in Los Altos de Cerro Azul

Tranquil cabin with WiFi in Los Altos de Cerro Azul
Los Altos de Cerro Azul
$206 nightly
The price is $206
Apr 14 - Apr 15
Total with taxes and fees
Tranquil cabin with WiFi in Los Altos de Cerro Azul
Room

Beautiful 2-bedroom apartment in Cerro Azul for your jungle getaway

Beautiful 2-bedroom apartment in Cerro Azul for your jungle getaway
Panamá
$140 nightly
The price is $140
Apr 14 - Apr 15
Total with taxes and fees
Beautiful 2-bedroom apartment in Cerro Azul for your jungle getaway
Terrace/patio

Your Menus de la Montaña country house awaits you

Your Menus de la Montaña country house awaits you
Panama
$230 nightly
The price is $230
Apr 14 - Apr 15
Total with taxes and fees
Your Menus de la Montaña country house awaits you
Interior

Hacienda La Perezosa in Cerro Azul

Hacienda La Perezosa in Cerro Azul
Panamá
$971 nightly
The price is $995
Apr 16 - Apr 17
Total with taxes and fees
Hacienda La Perezosa in Cerro Azul
Property grounds

Casa de Campo / E C O Aventura / Clima 18 a 25

Casa de Campo / E C O Aventura / Clima 18 a 25
Panamá
2.0 out of 10, (1 review)
$399 nightly
The price is $399
Apr 14 - Apr 15
Total with taxes and fees
Casa de Campo / E C O Aventura / Clima 18 a 25
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Eastern Panama Hotel Reviews

Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island

10/10 Excellent
"Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door. "
Ryan 4-night trip
Posted 1 month ago
Private Ocean-Front Cabin with private bathroom on San Blas Island

Find out more about Eastern Panama

Everything you need to know about Eastern Panama vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Eastern Panama vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Eastern Panama vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Eastern Panama vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Eastern Panama. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Eastern Panama in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $108 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Eastern Panama rentals

At Expedia, we put the best Eastern Panama vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Eastern Panama rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Eastern Panama vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Eastern Panama. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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