Eastern Panama Vacation Rentals from $144: Search Short-Term Rentals

Check prices for these dates

In two weeks

In two months

In three months

In four months

Our top choices for Eastern Panama vacation rentals

san blas luxury tour

Nusatupo

$138 nightly

Jul 15 - Jul 16

Total with taxes and fees

San Blas Private Oceanfront Cabin

Narganá

$359 nightly

Jul 15 - Jul 16

Total with taxes and fees

San Blas Private Beach Cabin

Narganá

$233 nightly

Jul 16 - Jul 17

Total with taxes and fees

Basic Cabin, Ocean View | Beach | On the beach, white sand, free beach shuttle

Sanblastourgy

Nargana

$221 nightly

Jul 20 - Jul 21

Total with taxes and fees

Private Over-Water Cabins on San Blas Island

Narganá

$309 nightly

Jul 23 - Jul 24

Total with taxes and fees

Basic Cabin, Multiple Beds, Balcony, Sea View | Beach/ocean view

San Blas Tour Aridub

Narganá

$131 nightly

Jul 15 - Jul 16

Total with taxes and fees

Private Over-the-Water Cabin in San Blas including Meals

Mirladub

$486 nightly

Jul 16 - Jul 17

Total with taxes and fees

Deluxe Beachfront 4-bedroom house in Colón Province

Colón Province

$382 nightly

Jul 15 - Jul 16

Total with taxes and fees

Lovely Caribbean Apartment with AC + Wifi + BBQ + Beach + Kitchen + Parking

Puerto Lindo

$245 nightly

Jul 15 - Jul 16

Total with taxes and fees

San Blas Private Over-the-Water Cabin

Narganá

"I liked the modern payment system that was used for booking the trip, the food was great, the location was as described. I disliked the communication with the reseller this booking goes through. They dropped the ball on communicating pickup time and itinerary confirmation, even when i tried calling and emailing them. I also disliked the value of what you get with this trip. Id expect better cleanliness and standards for this trip. I also disliked when the staff on the island said i needed to pay...

Andrew

$351 nightly

Jul 15 - Jul 16

Total with taxes and fees

Chalet, Balcony, Mountain View | Exterior

Tiny Cabin

Panamá

$97 nightly

Jul 20 - Jul 21

Total with taxes and fees

Charming cottage with 2 separate beds and a beautiful view of the river

Santa Rosa

Birgit U.

$146 nightly

Jul 15 - Jul 16

Total with taxes and fees

Jacuzy, pool and lake at the same house.

Colon

KENNETH E.

$69 nightly

Jul 15 - Jul 16

Total with taxes and fees

On the beach, sun loungers, beach towels

BEAUTIFUL APARTMENT IN FRONT OF THE SEA

Portobelo

Rosa M.

$180 nightly

Jul 16 - Jul 17

Total with taxes and fees

Elegance and comfort in old town panama

Panamá

PAMELA

$90 nightly

Jul 15 - Jul 16

Total with taxes and fees

Cozy and Safe Environment Close to the Airport.

Panamá

$82 nightly

Jul 15 - Jul 16

Total with taxes and fees

La Husseyenda. Private Birdwatching Retreat in Cerro Azul’s Mountains in Panama

Panamá

$264 nightly

Jul 15 - Jul 16

Total with taxes and fees

Beautiful 2-bedroom apartment in Cerro Azul for your jungle getaway

Panamá

$140 nightly

Jul 15 - Jul 16

Total with taxes and fees

Hacienda La Perezosa in Cerro Azul

Panamá

$967 nightly

Jul 16 - Jul 17

Total with taxes and fees

Hummingbird House/Casa de Colibri

Panamá

$324 nightly

Jul 15 - Jul 16

Total with taxes and fees

View all properties

Find vacation rentals that suit your style

Cabins

Apartments

Save an average of 15% on thousands of hotels when you're signed in

Sign in

Sign up, it's free

Top Eastern Panama Hotel Reviews

Ordovician Beach Resort

10/10 Excellent

"This resort is one of those special places you find that redefines a vacation. It is about a 15 minute boat ride from the dock, occupying the back side of Isla Grande and looking out to the Caribbean Sea. We were there during low season in July, and were fortunate enough to be one of just a few visitors staying at the time. The wonderful staff contributed to this being one of our most cherished travel destinations. Ricardo, Jose and Daniel at the restaurants were so incredibly warm and welcoming, in addition to Tiffany and Marcella in the office, and we quickly felt a part of their community. We enjoyed meeting the owners of the resort who introduced themselves over dinner and we’re also incredibly kind and friendly. Overall, the food was delicious, the rooms were clean and spacious, and our boys (10&12) love the games area and resort facilities. We would highly recommend!"

Ciel y Miel

10/10 Excellent

"Ciel y Miel is a beautiful boutique eco-lodge, but it’s important to know what to expect. It’s located inside a national park, so the final road is dirt and very remote. You park at the lower entrance and the staff drives you to the rooms. Our first night was an adjustment after a long drive. The property was very quiet (we visited during the low season), and the jungle sounds took some getting used to. By morning, we realized how peaceful and beautiful it really was. The rooms are spacious and clean with incredible views. The furniture is a little dated, and the room had a musty smell at first, which is common in the humid climate when A/C isn’t running. The infinity pool, beach club, and beach are stunning. The staff will drive you to the beach anytime, and they can arrange a boat trip to an even more secluded beach. I didn’t see 4 pools like advertised but it could be a seasonal thing. The highlight was the staff, especially José Enrique, who went above and beyond to make our stay special. The chef was outstanding—every meal was delicious and worth the price which was a bit high. (Skip the Aperol Spritz.) One suggestion: the listing advertises 4 pools, 3 restaurants, and a spa, but during our stay only 2 pools and 1 restaurant were available. It would be helpful if seasonal amenities were noted. My advice: arrive before sunset, stay at least 2 nights, and embrace the quiet. We left with wonderful memories and would happily return."

Ranchos de Chalia

10/10 Excellent

"Here's a natural, conversational review in English: We had a wonderful stay here. The hotel is beautiful, with an amazing pool overlooking both the ocean and the rainforest. Everything was very clean, and the beds were extremely comfortable. The staff were incredibly friendly and welcoming. The owner even helped arrange transportation for us to a nearby island beach, which we really appreciated. The water was crystal clear and perfect for swimming. The food was also excellent. We have some dietary restrictions, but there were still plenty of delicious options for us. The fried fish was outstanding, the chicken was delicious, and the breakfast was one of the highlights of our stay. We stayed in a smaller room, but it was very comfortable. There was a king-size bed for us, and our adult children each had their own separate bed. I highly recommend this place. Honestly, it’s the kind of destination where you can completely relax and never feel the need to leave the property. It was a true 100% vacation experience."

Find out more about Eastern Panama

Everything you need to know about Eastern Panama vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Eastern Panama vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Eastern Panama vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Eastern Panama vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Eastern Panama. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Eastern Panama in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $144 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Eastern Panama rentals

At Expedia, we put the best Eastern Panama vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Eastern Panama rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Eastern Panama vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Eastern Panama. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Expedia's Latest Trends

Hotels

Flights

Cars

luxury Car Rentals in Panama Canal Zone

Cruises

Cruises to Panama Canal Zone

Activities

Packages

Vacation Rentals

Panama Canal Zone Vacation Rentals

General

Room 1

Bundle & Save

OneKeyCash

Upfront pricing

Check prices for these dates

Our top choices for Eastern Panama vacation rentals

san blas luxury tour

San Blas Private Oceanfront Cabin

San Blas Private Beach Cabin

Sanblastourgy

Private Over-Water Cabins on San Blas Island

San Blas Tour Aridub

Private Over-the-Water Cabin in San Blas including Meals

Deluxe Beachfront 4-bedroom house in Colón Province

Lovely Caribbean Apartment with AC + Wifi + BBQ + Beach + Kitchen + Parking

San Blas Private Over-the-Water Cabin

Tiny Cabin

Charming cottage with 2 separate beds and a beautiful view of the river

Jacuzy, pool and lake at the same house.

BEAUTIFUL APARTMENT IN FRONT OF THE SEA

Elegance and comfort in old town panama

Cozy and Safe Environment Close to the Airport.

La Husseyenda. Private Birdwatching Retreat in Cerro Azul’s Mountains in Panama

Beautiful 2-bedroom apartment in Cerro Azul for your jungle getaway

Hacienda La Perezosa in Cerro Azul

Hummingbird House/Casa de Colibri

Find vacation rentals that suit your style

Top Eastern Panama Hotel Reviews

Ordovician Beach Resort

Ciel y Miel

Hotel Cocotal

Ranchos de Chalia

Private Ocean-Front Cabin with private bathroom on San Blas Island

Konsenda San Blas

Find out more about Eastern Panama

Expedia's Latest Trends

Go further with the Expedia app