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Compare 184 hotels in Lee County with room rates, reviews, and availability. Most hotels are fully refundable.

Terrace/patio
Cobblestone Inn & Suites - Fort Madison

Cobblestone Inn & Suites - Fort Madison

2.5 star property
Fort Madison
9.4 out of 10, Exceptional, (646)
"Always love staying here while visiting family. Very clean and comfortable beds "
United States
Jessica
$75 nightly
The price is $84
Dec 8 - Dec 9
Total with taxes and fees
Cobblestone Inn & Suites - Fort Madison
Suite, 1 King Bed with Sofa bed, Non Smoking | In-room safe, desk, iron/ironing board, free cribs/infant beds
Quality Inn & Suites Keokuk North

Quality Inn & Suites Keokuk North

2.5 star property
Keokuk
8.4 out of 10, Very Good, (749)
"Great staff! Clean hotel!"
United States
Matthew
$80 nightly
The price is $90
Dec 28 - Dec 29
Total with taxes and fees
Quality Inn & Suites Keokuk North
Indoor pool, open 7 AM to 10 PM, pool umbrellas
Quality Inn & Suites Fort Madison near Hwy 61

Quality Inn & Suites Fort Madison near Hwy 61

2.5 star property
Fort Madison
8.6 out of 10, Excellent, (567)
"Everything was great. The rooms were clean, the staff were very nice and kept thulings stocked. Overall a great trip. "
United States
Ashley
$80 nightly
The price is $89
Jan 4 - Jan 5, 2026
Total with taxes and fees
Quality Inn & Suites Fort Madison near Hwy 61
Lobby
Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk

2.5 star property
Keokuk
6.2 out of 10, (489)
"Great location for geode hunting. Irish Pub behind the hotel is the best."
United States
Marty
$53 nightly
The price is $59
Jan 4 - Jan 5, 2026
Total with taxes and fees
Baymont by Wyndham Keokuk
Free daily buffet breakfast
Hampton Inn Keokuk

Hampton Inn Keokuk

2.5 star property
Keokuk
8.8 out of 10, Excellent, (639)
"Very good stay. I’ll definitely stay there again "
United States
Tammy
$95 nightly
The price is $107
Dec 18 - Dec 19
Total with taxes and fees
Hampton Inn Keokuk
Lobby
Super 8 by Wyndham Fort Madison

Super 8 by Wyndham Fort Madison

2.0 star property
Fort Madison
6.8 out of 10, (324)
"I would definitely stay there again!"
United States
Marcia
$65 nightly
The price is $73
Dec 8 - Dec 9
Total with taxes and fees
Super 8 by Wyndham Fort Madison
Room amenity
Rivers Inn Fort Madison

Rivers Inn Fort Madison

2.0 star property
Fort Madison
6.2 out of 10, (165)
"Wonderful lady at desk, quite place,not far from town have been here several times and will be back"
United States
lance
$50 nightly
The price is $56
Dec 9 - Dec 10
Total with taxes and fees
Rivers Inn Fort Madison
Standard Single Room, 1 King Bed | Private kitchenette | Fridge, microwave
Budget Inn

Budget Inn

2.0 star property
Keokuk
8.0 out of 10, Very Good, (71)
"Friendly front desk staff and accommodating."
United States
Guillermo
$60 nightly
The price is $67
Dec 8 - Dec 9
Total with taxes and fees
Budget Inn
Luxury Suite, 1 King Bed with Sofa bed, River View | Living area | LED TV, books
Kingsley Inn

Kingsley Inn

3.5 star property
Fort Madison
9.2 out of 10, Wonderful, (485)
"Excellent accommodation, beautiful hotel! Checking with code was good! Great place to watch trains!"
United States
Gerald
Kingsley Inn
Standard Room, 2 Double Beds | Iron/ironing board, free WiFi, bed sheets
Chief Motel

Chief Motel

2.5 star property
Keokuk
7.8 out of 10, Good, (111)
"The daily cleaning and room care amazed us. Totally over the top service. "
United States
Robert
$60 nightly
The price is $67
Dec 8 - Dec 9
Total with taxes and fees
Chief Motel
Family Cottage | Free WiFi, bed sheets
Johnstone Mansion

Johnstone Mansion

3.0 star property
Keokuk
8.4 out of 10, Very Good, (5)
"Absolutely loved this beautiful restored old world home! We could walk around and look at the amazing Victorian interior and furnishings for days. Peter was an amazing host and we hope to come back to visit some day. "
United States
Darlene
$198 nightly
The price is $222
Dec 13 - Dec 14
Total with taxes and fees
Johnstone Mansion
Private kitchen
Stay in this Unique SE Iowa Apt

Stay in this Unique SE Iowa Apt

Fort Madison
10.0 out of 10, Exceptional, (14)
"Would definately stay here agan."
United States
Christina
$129 nightly
The price is $144
Dec 19 - Dec 20
Total with taxes and fees
Stay in this Unique SE Iowa Apt
Fridge, microwave, oven, stovetop
Beautiful Riverview Apt Located in Downtown Fort Madison

Beautiful Riverview Apt Located in Downtown Fort Madison

Fort Madison
10.0 out of 10, Exceptional, (5)
"I was here for a couple weeks for work, and Rebecca was responsive with any questions, very friendly, and an excellent host!"
United States
Sam G.
$186 nightly
The price is $208
Dec 10 - Dec 11
Total with taxes and fees
Beautiful Riverview Apt Located in Downtown Fort Madison
Property grounds
Grand Victorian on the Mississippi

Grand Victorian on the Mississippi

Fort Madison
9.8 out of 10, Exceptional, (22)
"The Grand Victorian is AMAZING!! The house is gorgeous and beautifully decorated. Everything was there that we needed, the area was peaceful and easy to access. Highly recommend staying here! "
United States
Andrea S.
$383 nightly
The price is $429
Dec 9 - Dec 10
Total with taxes and fees
Grand Victorian on the Mississippi
Interior
Johnston Mansion Bed and Breakfast price shown is Vrbo Mansion price

Johnston Mansion Bed and Breakfast price shown is Vrbo Mansion price

Keokuk
9.0 out of 10, Wonderful, (2)
"Beautiful place in lovely, walkable neighborhood near the Mississippi. The hosts couldn't have been more accommodating or kind."
United States
Kathryn C.
$1,660 nightly
The price is $1,859
Dec 9 - Dec 10
Total with taxes and fees
Johnston Mansion Bed and Breakfast price shown is Vrbo Mansion price
Smart TV, fireplace
Stay in Historic Downtown Keokuk

Stay in Historic Downtown Keokuk

Keokuk
10.0 out of 10, Exceptional, (34)
"We always stay here when we are in town and It is always phenomenal! "
United States
Crystal M.
$229 nightly
The price is $256
Dec 8 - Dec 9
Total with taxes and fees
Stay in Historic Downtown Keokuk
In-room safe, desk, blackout drapes, soundproofing
Super 8 by Wyndham Keokuk

Super 8 by Wyndham Keokuk

2.0 star property
Keokuk
7.6 out of 10, Good, (638)
"Enjoyed my stay"
United States
Paul
Super 8 by Wyndham Keokuk
Exterior
Charming 2-bedroom cottage with WiFi, AC in enjoyable Fort Madison

Charming 2-bedroom cottage with WiFi, AC in enjoyable Fort Madison

Fort Madison
10.0 out of 10, Exceptional, (2)
"Very cute, well equipped small cottage. Street parking is on a bit of a hill...I was able to back my motorcycle into the small carport located on the alley. Quiet and comfortable."
United States
Joe E.
Charming 2-bedroom cottage with WiFi, AC in enjoyable Fort Madison
Smart TV
Mayor's Manor - with everything you need in a homebase get away. Pet friendly.

Mayor's Manor - with everything you need in a homebase get away. Pet friendly.

Montrose
10.0 out of 10, Exceptional, (13)
"Very comfortable and convenient for our stay. Highly recommend."
United States
bob f.
Mayor's Manor - with everything you need in a homebase get away. Pet friendly.
Smart TV, DVD player, books, video library
3 Blocks from the Mississippi River in the Park-To-Park Historic District.

3 Blocks from the Mississippi River in the Park-To-Park Historic District.

2.0 star property
Fort Madison
10.0 out of 10, Exceptional, (1)
3 Blocks from the Mississippi River in the Park-To-Park Historic District.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Lee County Hotel Reviews

AmericInn by Wyndham Mount Pleasant

AmericInn by Wyndham Mount Pleasant

10/10 Excellent
"Room was very clean and bathroom fixtures were up to date. Breakfast was better than average and fresh. Very quiet. Didn't use pool, but it was open late and looked fresh and clean."
Bob 1-night trip
Posted 2 days ago
AmericInn by Wyndham Mount Pleasant

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