Title: South Carolina Midlands Vacation Rentals from $110: Search Short-Term Rentals | Expedia.com

[South Carolina Midlands Travel Guide](https://expedia.com/South-Carolina-Midlands.dx6057938)[Hotels in South Carolina Midlands](https://expedia.com/South-Carolina-Midlands-Hotels.d6057938.Travel-Guide-Hotels)[Flights to South Carolina Midlands](https://expedia.com/Cheap-Flights-To-South-Carolina-Midlands.d6057938.Travel-Guide-Flights)[Things to do in South Carolina Midlands](https://expedia.com/Things-To-Do-In-South-Carolina-Midlands.d6057938.Travel-Guide-Activities)[Car Rentals in South Carolina Midlands](https://expedia.com/Car-Rentals-In-South-Carolina-Midlands.d6057938.Car-Rental-Guide)[South Carolina Midlands Vacation Packages](https://expedia.com/South-Carolina-Midlands.d6057938.Destination-Travel-Guides)

![South Carolina State House](https://images.trvl-media.com/place/6082681/1934af6a-1aa9-4e01-8cd3-8eb8fe4af18f.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6082681/1934af6a-1aa9-4e01-8cd3-8eb8fe4af18f.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

## Check prices for these dates

In two weeks

[Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=6057938&startDate=2026-03-27&endDate=2026-03-29&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 8 - May 10](https://www.expedia.com/Hotel-Search?regionId=6057938&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Jun 5 - Jun 7](https://www.expedia.com/Hotel-Search?regionId=6057938&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jul 3 - Jul 5](https://www.expedia.com/Hotel-Search?regionId=6057938&startDate=2026-07-03&endDate=2026-07-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for South Carolina Midlands vacation rentals

![Exterior](https://images.trvl-media.com/lodging/95000000/94800000/94797300/94797237/f4ad045c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Cabin | Private kitchen | Mini-fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/95000000/94800000/94797300/94797237/4ba35d55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Cabin | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/95000000/94800000/94797300/94797237/721a18d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Cabin | Bathroom | Towels](https://images.trvl-media.com/lodging/95000000/94800000/94797300/94797237/8dea4f30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabin in Charlotte

[](https://www.expedia.com/Charlotte-Hotels-Carowinds-Camp-Wilderness.h94797237.Hotel-Information)

8.8/10

Excellent

(38 reviews)

"Clean room. Very friendly and efficient staff."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Denise

$114 nightly

$131 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Charlotte-Hotels-Carowinds-Camp-Wilderness.h94797237.Hotel-Information)

![Land view from property](https://images.trvl-media.com/lodging/96000000/95330000/95321700/95321677/a9a6cfbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Individually decorated, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/96000000/95330000/95321700/95321677/fa256a38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lake view](https://images.trvl-media.com/lodging/96000000/95330000/95321700/95321677/6076626b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Cabin, 1 Queen Bed, Lake View | Individually decorated, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/96000000/95330000/95321700/95321677/2b7f07e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabin in Steele Creek

[](https://www.expedia.com/Charlotte-Hotels-Long-Cove-Resort-Marina.h95321677.Hotel-Information)

8.6/10

Excellent

(246 reviews)

"I had an excellent time at Long Cove. The cabin I stayed in was very clean and smelled fresh upon arrival. The view of the lake from my porch was spectacular. It felt like being away from the city's hustle and bustle, yet it was only a short drive to shopping and food. I would recommend this place every time!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kathryn

$173 nightly

$189 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Charlotte-Hotels-Long-Cove-Resort-Marina.h95321677.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/109000000/108750000/108744500/108744467/042e0d64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House, 4 Bedroom, 2 Bathrooms | 4 bedrooms, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/109000000/108750000/108744500/108744467/3c8b1a15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House, 4 Bedroom, 2 Bathrooms | Private kitchen](https://images.trvl-media.com/lodging/109000000/108750000/108744500/108744467/390b6b50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/109000000/108750000/108744500/108744467/c3110805.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel in Hopkins

[](https://www.expedia.com/Hopkins-Hotels-Fort-Jackson-Stay-At-The-Breeze-On-Inn.h108744467.Hotel-Information)

$645 nightly

$714 total

Mar 16 - Mar 17

Total with taxes and fees

[](https://www.expedia.com/Hopkins-Hotels-Fort-Jackson-Stay-At-The-Breeze-On-Inn.h108744467.Hotel-Information)

![Loft 007 Ft. on HGTV | Private kitchen | Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/46000000/45150000/45148000/45147909/73e0b2e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![55-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/46000000/45150000/45148000/45147909/6d4cd723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, memory foam beds](https://images.trvl-media.com/lodging/46000000/45150000/45148000/45147909/df30a240.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/46000000/45150000/45148000/45147909/9bed4523.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aparthotel in Rosewood

[](https://www.expedia.com/Columbia-Hotels-The-Hangar-Lofts-Hotel.h45147909.Hotel-Information)

8.8/10

Excellent

(77 reviews)

"Great place! Clean and spacious. The owner was very welcoming and friendly. He made the experience very pleasant. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Matt

$160 nightly

$179 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Columbia-Hotels-The-Hangar-Lofts-Hotel.h45147909.Hotel-Information)

![TV](https://images.trvl-media.com/lodging/110000000/109030000/109029100/109029091/0e6a5b41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/110000000/109030000/109029100/109029091/03f6f533.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/110000000/109030000/109029100/109029091/e1e71064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/110000000/109030000/109029100/109029091/61459727.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in West Columbia

[](https://www.expedia.com/West-Columbia-Hotels-Columbia-Duet-2-Units.h109029091.Hotel-Information)

$1,277 nightly

$1,374 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/West-Columbia-Hotels-Columbia-Duet-2-Units.h109029091.Hotel-Information)

![Townhome | Private kitchen](https://images.trvl-media.com/lodging/126000000/125600000/125593700/125593630/d092381b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Townhome | Private kitchen](https://images.trvl-media.com/lodging/126000000/125600000/125593700/125593630/18dacd1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Townhome | Living area](https://images.trvl-media.com/lodging/126000000/125600000/125593700/125593630/9aa74be6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Townhome | Interior](https://images.trvl-media.com/lodging/126000000/125600000/125593700/125593630/18d8e1a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Townhouse in Pineville

[](https://www.expedia.com/Charlotte-Hotels-Upscale-King-3BR-Townhouse-In-Pineville.h125593630.Hotel-Information)

$216 nightly

$250 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Charlotte-Hotels-Upscale-King-3BR-Townhouse-In-Pineville.h125593630.Hotel-Information)

![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/126000000/125760000/125753300/125753294/c52dab3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/126000000/125760000/125753300/125753294/c1b32a1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/126000000/125760000/125753300/125753294/a4c5a198.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/126000000/125760000/125753300/125753294/67877b51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cottage in Charlotte

[](https://www.expedia.com/Charlotte-Hotels-Charlotte-Area-Home-Near-Lake-Wylie.h125753294.Hotel-Information)

[](https://www.expedia.com/Charlotte-Hotels-Charlotte-Area-Home-Near-Lake-Wylie.h125753294.Hotel-Information)

![Courtyard](https://images.trvl-media.com/lodging/72000000/71950000/71945700/71945688/970cfe28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71950000/71945700/71945688/2b2bb3f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71950000/71945700/71945688/03808077.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71950000/71945700/71945688/5ac04ce0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aparthotel in Rock Hill

[](https://www.expedia.com/Rock-Hill-Hotels-StayAPT-Suites-Rock-Hill.h71945688.Hotel-Information)

8.4/10

Very Good

(213 reviews)

"Clean and staff was very friendly. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Cydney

$99 nightly

$110 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/Rock-Hill-Hotels-StayAPT-Suites-Rock-Hill.h71945688.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/72000000/71950000/71943400/71943321/be58ae40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71950000/71943400/71943321/e9758649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71950000/71943400/71943321/917b8b10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/72000000/71950000/71943400/71943321/b733a543.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aparthotel in Irmo

[](https://www.expedia.com/Irmo-Hotels-StayAPT-Suites-Columbia-Irmo-Harbison.h71943321.Hotel-Information)

8.6/10

Excellent

(346 reviews)

"Great stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ty

$109 nightly

$119 total

Mar 30 - Mar 31

Total with taxes and fees

[](https://www.expedia.com/Irmo-Hotels-StayAPT-Suites-Columbia-Irmo-Harbison.h71943321.Hotel-Information)

![Townhome | Private kitchen](https://images.trvl-media.com/lodging/122000000/121050000/121042800/121042706/a0809dae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Townhome | Private kitchen](https://images.trvl-media.com/lodging/122000000/121050000/121042800/121042706/0df1b4cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Townhome | Living area](https://images.trvl-media.com/lodging/122000000/121050000/121042800/121042706/e65665eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Townhome | Living area](https://images.trvl-media.com/lodging/122000000/121050000/121042800/121042706/9d82f0ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Townhouse in Pineville

[](https://www.expedia.com/Charlotte-Hotels-Upscale-King-3BR-Townhouse-In-Pineville.h121042706.Hotel-Information)

$223 nightly

$258 total

Mar 23 - Mar 24

Total with taxes and fees

[](https://www.expedia.com/Charlotte-Hotels-Upscale-King-3BR-Townhouse-In-Pineville.h121042706.Hotel-Information)

![Deluxe House, 5 Bedrooms, Patio | Living area | TV](https://images.trvl-media.com/lodging/110000000/109300000/109291700/109291605/cfd59cb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/110000000/109300000/109291700/109291605/cc3b4366.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe House, 5 Bedrooms, Patio | 5 bedrooms, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/110000000/109300000/109291700/109291605/593a52e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe House, 5 Bedrooms, Patio | Private kitchen](https://images.trvl-media.com/lodging/110000000/109300000/109291700/109291605/3950eae5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Columbia

[](https://www.expedia.com/Columbia-Hotels-Chic-Mid-Century-Hub.h109291605.Hotel-Information)

2.0/10

(1 review)

"Está demasiado descuidada y si hablamos de la limpieza es terrible la parece ser que no limpian "

![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg)

Karen

$585 nightly

$647 total

Mar 16 - Mar 17

Total with taxes and fees

[](https://www.expedia.com/Columbia-Hotels-Chic-Mid-Century-Hub.h109291605.Hotel-Information)

![Townhome | Dining room](https://images.trvl-media.com/lodging/121000000/120620000/120615300/120615225/6466310f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Balcony](https://images.trvl-media.com/lodging/121000000/120620000/120615300/120615225/817b19ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Townhome | Free WiFi](https://images.trvl-media.com/lodging/121000000/120620000/120615300/120615225/d01113be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Townhome | Living area | 32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/121000000/120620000/120615300/120615225/00775e15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Townhouse in Double Oaks

[](https://www.expedia.com/Charlotte-Hotels-Luxe-3BR-Townhouse-In-Camp-North-End.h120615225.Hotel-Information)

10/10

Exceptional

(1 review)

$232 nightly

$268 total

Mar 16 - Mar 17

Total with taxes and fees

[](https://www.expedia.com/Charlotte-Hotels-Luxe-3BR-Townhouse-In-Camp-North-End.h120615225.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/121000000/120420000/120414300/120414269/w1199h800x1y1-63ebad8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/121000000/120420000/120414300/120414269/w1199h799x1y1-7d3a7237.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free WiFi](https://images.trvl-media.com/lodging/121000000/120420000/120414300/120414269/df9413dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/121000000/120420000/120414300/120414269/w1200h799x0y1-53a95658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Townhouse in Greenville

[](https://www.expedia.com/Charlotte-Hotels-Luxe-King-3BR-Townhouse-In-Uptown-CLT.h120414269.Hotel-Information)

10/10

Exceptional

(1 review)

$239 nightly

$276 total

Mar 18 - Mar 19

Total with taxes and fees

[](https://www.expedia.com/Charlotte-Hotels-Luxe-King-3BR-Townhouse-In-Uptown-CLT.h120414269.Hotel-Information)

![Townhome | Free WiFi](https://images.trvl-media.com/lodging/126000000/125190000/125187600/125187558/636aeeae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Townhome | Living area](https://images.trvl-media.com/lodging/126000000/125190000/125187600/125187558/4f870fc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Townhome | Living area](https://images.trvl-media.com/lodging/126000000/125190000/125187600/125187558/f6a2a633.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Townhome | Private kitchen](https://images.trvl-media.com/lodging/126000000/125190000/125187600/125187558/15e64a8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Townhouse in Mountain Island

[](https://www.expedia.com/Charlotte-Hotels-Luxe-King-4BR-Townhouse-To-Uptown-CLT.h125187558.Hotel-Information)

$259 nightly

$299 total

Mar 16 - Mar 17

Total with taxes and fees

[](https://www.expedia.com/Charlotte-Hotels-Luxe-King-4BR-Townhouse-To-Uptown-CLT.h125187558.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/107000000/106050000/106044900/106044858/c7d5ba5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Gym](https://images.trvl-media.com/lodging/107000000/106050000/106044900/106044858/37f8220a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![BBQ/picnic area](https://images.trvl-media.com/lodging/107000000/106050000/106044900/106044858/5fe4aae8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/107000000/106050000/106044900/106044858/83eaf1a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aparthotel in Optimist Park

[](https://www.expedia.com/Kasa-At-Cortland-NoDa-Charlotte.h106044858.Hotel-Information)

9.0/10

Wonderful

(135 reviews)

"Always a great stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

shana

$85 nightly

$98 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Kasa-At-Cortland-NoDa-Charlotte.h106044858.Hotel-Information)

![Panoramic Tent | Lake view](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/caef79e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin, 1 Bedroom, Non Smoking, Lake View | Individually decorated, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/b0419165.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin, 1 Bedroom, Non Smoking, Lake View | Terrace/patio](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/w4138h5635x0y0-48933ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin, 1 Bedroom, Non Smoking, Lake View | Living area](https://images.trvl-media.com/lodging/92000000/91250000/91244700/91244689/ee0f57db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aparthotel in Eutawville

[](https://www.expedia.com/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information)

8.6/10

Excellent

(90 reviews)

"Super quaint, quiet, nice little get away."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Karen

$108 nightly

$120 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Eutawville-Hotels-Bells-Marina-Resort.h91244689.Hotel-Information)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115900000/115898300/115898277/97fe27f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115900000/115898300/115898277/8cfafc66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115900000/115898300/115898277/b574d4f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115900000/115898300/115898277/de379cc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cottage in Biddleville

[](https://www.expedia.com/Charlotte-Hotels-2-Mi-To-Uptown-Charlotte-Home-W-Large-Yard.h115898277.Hotel-Information)

$257 nightly

$297 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Charlotte-Hotels-2-Mi-To-Uptown-Charlotte-Home-W-Large-Yard.h115898277.Hotel-Information)

![Private kitchen](https://images.trvl-media.com/lodging/120000000/119990000/119989000/119988964/3fff6520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/120000000/119990000/119989000/119988964/aa365e5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/120000000/119990000/119989000/119988964/e7fb47fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Queen Bed, Non Smoking | Private kitchen](https://images.trvl-media.com/lodging/120000000/119990000/119989000/119988964/d3ff6b72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in NoDa

[](https://www.expedia.com/Charlotte-Hotels-Inkwell.h119988964.Hotel-Information)

$229 nightly

$245 total

Apr 1 - Apr 2

Total with taxes and fees

[](https://www.expedia.com/Charlotte-Hotels-Inkwell.h119988964.Hotel-Information)

![Family House, 3 Bedrooms, Non Smoking | Living room | 50-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/115000000/114450000/114449100/114449094/c18c5ba3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/115000000/114450000/114449100/114449094/b1fb8781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family House, 3 Bedrooms, Non Smoking | Living room | 50-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/115000000/114450000/114449100/114449094/74a89e35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family House, 3 Bedrooms, Non Smoking | 3 bedrooms, individually decorated, individually furnished, free WiFi](https://images.trvl-media.com/lodging/115000000/114450000/114449100/114449094/31dd66ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Charlotte

[](https://www.expedia.com/Charlotte-Hotels-Quail-Ridge-3BR-House.h114449094.Hotel-Information)

10/10

Exceptional

(3 reviews)

"We stayed here for a week in town for baseball training. Everything was perfect. We will stay here again in the future. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christopher

$284 nightly

$327 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Charlotte-Hotels-Quail-Ridge-3BR-House.h114449094.Hotel-Information)

![Townhome | Outdoor dining](https://images.trvl-media.com/lodging/126000000/125670000/125660400/125660376/66692188.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Townhome | Interior](https://images.trvl-media.com/lodging/126000000/125670000/125660400/125660376/a26efe0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Townhome | Free WiFi](https://images.trvl-media.com/lodging/126000000/125670000/125660400/125660376/aaf4b765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Townhome | Exterior](https://images.trvl-media.com/lodging/126000000/125670000/125660400/125660376/efa0ea05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Townhouse in Greenville

[](https://www.expedia.com/Charlotte-Hotels-Luxe-King-4BR-Townhouse-In-Uptown-CLT.h125660376.Hotel-Information)

$242 nightly

$279 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Charlotte-Hotels-Luxe-King-4BR-Townhouse-In-Uptown-CLT.h125660376.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.com/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America&regionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-06-10&d1=2026-06-10&endDate=2026-06-13&d2=2026-06-13&lodging=CABIN)

Cottages

[](https://www.expedia.com/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America&regionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-06-10&d1=2026-06-10&endDate=2026-06-13&d2=2026-06-13&lodging=COTTAGE)

Houseboats

[](https://www.expedia.com/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America&regionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-06-10&d1=2026-06-10&endDate=2026-06-13&d2=2026-06-13&lodging=HOUSE_BOAT)

Villas

[](https://www.expedia.com/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America&regionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-06-10&d1=2026-06-10&endDate=2026-06-13&d2=2026-06-13&lodging=VILLA)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America&regionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-06-10&d1=2026-06-10&endDate=2026-06-13&d2=2026-06-13&lodging=VACATION_HOME)

Condos

[](https://www.expedia.com/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America&regionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-06-10&d1=2026-06-10&endDate=2026-06-13&d2=2026-06-13&lodging=CONDO)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America&regionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-06-10&d1=2026-06-10&endDate=2026-06-13&d2=2026-06-13&lodging=APARTMENT)

Aparthotels

[](https://www.expedia.com/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America&regionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-06-10&d1=2026-06-10&endDate=2026-06-13&d2=2026-06-13&lodging=APART_HOTEL)

Chalets

[](https://www.expedia.com/Hotel-Search?destination=South+Carolina+Midlands%2C+South+Carolina%2C+United+States+of+America&regionId=6057938&latLong=34.070287%2C-80.861504&adults=2&startDate=2026-06-10&d1=2026-06-10&endDate=2026-06-13&d2=2026-06-13&lodging=CHALET)

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## Top South Carolina Midlands Hotel Reviews

![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg)

### Howard Johnson by Wyndham Florence

4/10 Poor

"If your expectations are low then this is the place for you! Don’t know how it received such high ratings but this place is definitely dated and unbecoming! And the breakfast is basically nonexistent (just some bread, cereal and apples, not even an assortment of fruit) with juice and coffee! Unfortunately I went off of the previous reviews and the first few pics I saw! Lesson learned!"

[](https://expedia.com/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information)

![Hyatt Place Florence Downtown](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166_y.jpg)

### Hyatt Place Florence Downtown

4/10 Poor

"The worst hotel bed I’ve ever tried to sleep on. Stay somewhere else. "

[](https://expedia.com/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information)

![Tru By Hilton Columbia Downtown](https://images.trvl-media.com/lodging/111000000/110650000/110648500/110648494/w3837h2557x3y3-06093940_y.jpg)

### Tru By Hilton Columbia Downtown

10/10 Excellent

"Very nice accommodations. Best free breakfast ever. "

[](https://expedia.com/Columbia-Hotels-Tru-By-Hilton-Columbia-Downtown.h110648494.Hotel-Information)

![Sleep Inn Columbia](https://images.trvl-media.com/lodging/1000000/130000/127000/126908/de238acf_y.jpg)

### Sleep Inn Columbia

10/10 Excellent

"Friendly and clean"

[](https://expedia.com/Columbia-Hotels-Sleep-Inn-At-Bush-River-Road.h126908.Hotel-Information)

![La Quinta Inn by Wyndham Columbia SE / Fort Jackson](https://images.trvl-media.com/lodging/1000000/10000/5100/5038/e9b1ea9e_y.jpg)

### La Quinta Inn by Wyndham Columbia SE / Fort Jackson

2/10 Terrible

"No one at reception noticed 2 people out front vaping. It was the front desk person and another employee. She was very rude and unable to properly explain the pet policy. Told us to leave if we didn't like it. And refused to call the manager when requesting it. Said she didnt want to. Several people hanging out in parking lot with laptops for long periods of time that were not guest. There are so many hotels surrounding this one I wouldn't pick one that's run this unprofessionally."

[](https://expedia.com/Columbia-Hotels-La-Quinta-Inn-By-Wyndham-Columbia-SE-Fort-Jackson.h5038.Hotel-Information)

![Wyndham Garden Columbia/Ft. Jackson](https://images.trvl-media.com/lodging/78000000/77820000/77814700/77814689/e6cbdb45_y.jpg)

### Wyndham Garden Columbia/Ft. Jackson

6/10 Okay

"Yes"

[](https://expedia.com/Columbia-Hotels-Hotel-Columbia-Inn-Suites.h77814689.Hotel-Information)

![Hilton Garden Inn Columbia/Harbison](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513707/f8933df9_y.jpg)

### Hilton Garden Inn Columbia/Harbison

10/10 Excellent

"Front desk staff was wonderful. I was in and out without issue. Check in was a sinch. Miesha texted to check in on me to make sure my stay was sufficient. I will always choose this location whenever I am in this area."

[](https://expedia.com/Columbia-Hotels-Hilton-Garden-Inn-ColumbiaHarbison.h1513707.Hotel-Information)

![Doubletree by Hilton Columbia, SC](https://images.trvl-media.com/lodging/1000000/10000/1100/1090/77a41033_y.jpg)

### Doubletree by Hilton Columbia, SC

10/10 Excellent

"I will stay here again. The room was clean. The bed was sooooo comfortable. It was quiet and restful for the 4 days I was there. "

[](https://expedia.com/Columbia-Hotels-Doubletree-By-Hilton-Columbia.h1090.Hotel-Information)

![Graduate by Hilton Columbia SC](https://images.trvl-media.com/lodging/3000000/2520000/2515100/2515057/22f12a1f_y.jpg)

### Graduate by Hilton Columbia SC

10/10 Excellent

"Not your typical hotel.... Provides a unique localized feel.... borders the USC campus giving it a great location....stayed here with business colleagues and everyone enjoyed the experience "

[](https://expedia.com/Columbia-Hotels-Graduate-Columbia.h2515057.Hotel-Information)

## Find out more about South Carolina Midlands

**Everything you need to know about South Carolina Midlands vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the South Carolina Midlands vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect South Carolina Midlands vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**South Carolina Midlands vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in South Carolina Midlands. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit South Carolina Midlands in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $110 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on South Carolina Midlands rentals**

At Expedia, we put the best South Carolina Midlands vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top South Carolina Midlands rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream South Carolina Midlands vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around South Carolina Midlands. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Explore a world of travel with Expedia

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- [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations)

- [Vacation Homes in South Carolina Midlands ](https://expedia.com/South-Carolina-Midlands-Private-Vacation-Homes.d6057938-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Apartments in South Carolina Midlands ](https://expedia.com/South-Carolina-Midlands-Apartments.d6057938-aaApartments.Travel-Guide-Accommodation)
- [Cottages in South Carolina Midlands ](https://expedia.com/South-Carolina-Midlands-Cottages.d6057938-aaCottages.Travel-Guide-Accommodation)
- [Motels in South Carolina Midlands ](https://expedia.com/South-Carolina-Midlands-Motels.d6057938-aaMotels.Travel-Guide-Accommodation)
- [Condo Rentals in South Carolina Midlands ](https://expedia.com/South-Carolina-Midlands-Condos.d6057938-aaCondos.Travel-Guide-Accommodation)
- [Cabin Rentals in South Carolina Midlands ](https://expedia.com/South-Carolina-Midlands-Cabins.d6057938-aaCabins.Travel-Guide-Accommodation)
- [Farmstay in South Carolina Midlands ](https://expedia.com/South-Carolina-Midlands-Agritourism.d6057938-aaAgritourism.Travel-Guide-Accommodation)
- [B&B in South Carolina Midlands ](https://expedia.com/South-Carolina-Midlands-Bed-And-Breakfast.d6057938-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Guest Houses in South Carolina Midlands ](https://expedia.com/South-Carolina-Midlands-Guest-Houses.d6057938-aaGuestHouses.Travel-Guide-Accommodation)
- [Aparthotels in South Carolina Midlands ](https://expedia.com/South-Carolina-Midlands-Apart-Hotels.d6057938-aaApartHotels.Travel-Guide-Accommodation)
- [Resorts in South Carolina Midlands ](https://expedia.com/South-Carolina-Midlands-Resorts.d6057938-aaResorts.Travel-Guide-Accommodation)
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- [Inns in South Carolina Midlands ](https://expedia.com/South-Carolina-Midlands-Inns.d6057938-aaInns.Travel-Guide-Accommodation)

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- [Adults Only Resorts & Hotels in Coastal South Carolina](https://expedia.com/Coastal-South-Carolina-Hotels-Adults-Only-Resorts.0-0-d6057937-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels)
- [Hotels with Free Airport Shuttle in Greenville - Spartanburg](https://expedia.com/Greenville-Spartanburg-Hotels-Hotels-With-Free-Airport-Shuttle.0-0-d6035267-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels)
- [Hotels in Greenville - Spartanburg](https://expedia.com/Greenville-Spartanburg-Hotels.d6035267.Travel-Guide-Hotels)

Flights

- [Cheap Flights to Greenville - Spartanburg](https://expedia.com/Cheap-Flights-To-Greenville-Spartanburg.d6035267.Travel-Guide-Flights)
- [Cheap Flights to Upstate South Carolina](https://expedia.com/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)

Cars

- [Easirent Car Rentals In Upstate South Carolina](https://expedia.com/Easirent-Car-Rentals-In-Upstate-South-Carolina.d6057939-c1039.Car-Rental-Guide-Suppliers)
- [minivan Car Rentals in Greenville - Spartanburg](https://expedia.com/Minivan-Car-Rentals-In-Greenville-Spartanburg.d6035267-tMinivan.Car-Rental-Guide-Class)
- [Orlando Car Rentals In Greenville Spartanburg](https://expedia.com/Orlando-Car-Rentals-In-Greenville-Spartanburg.d6035267-c1047.Car-Rental-Guide-Suppliers)
- [midsize Car Rentals in Greenville - Spartanburg](https://expedia.com/Midsize-Car-Rentals-In-Greenville-Spartanburg.d6035267-tMidsize.Car-Rental-Guide-Class)

Activities

- [Things to do in Greenville - Spartanburg](https://expedia.com/Things-To-Do-In-Greenville-Spartanburg.d6035267.Travel-Guide-Activities)
- [Things to do in Upstate South Carolina](https://expedia.com/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)
- [Things to do in Coastal South Carolina](https://expedia.com/Things-To-Do-In-Coastal-South-Carolina.d6057937.Travel-Guide-Activities)

Packages

- [Coastal South Carolina Vacation](https://expedia.com/Coastal-South-Carolina.d6057937.Destination-Travel-Guides)
- [South Carolina Lowcountry All Inclusive Vacation Packages](https://expedia.com/lp/theme-vacations/yoga-vacations/553248635975748945/South-Carolina-Lowcountry)
- [Upstate South Carolina All Inclusive Vacation Packages](https://expedia.com/lp/theme-vacations/golf-vacations/6057939/Upstate-South-Carolina)

Vacation Rentals

- [Upstate South Carolina Vacation Rentals](https://expedia.com/Upstate-South-Carolina-Vacation-Rentals.d6057939.Travel-Guide-VacationRentals)

General

- [Visit Upstate South Carolina](https://expedia.com/Upstate-South-Carolina.dx6057939)
- [Visit Greenville - Spartanburg](https://expedia.com/Greenville-Spartanburg.dx6035267)
- [Visit Coastal South Carolina](https://expedia.com/Coastal-South-Carolina.dx6057937)