South Carolina Midlands Vacation Rentals

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Check prices for these dates

In two weeks
Jul 3 - Jul 5
In two months
Aug 14 - Aug 16
In three months
Sep 11 - Sep 13
In four months
Oct 9 - Oct 11

Our top choices for South Carolina Midlands vacation rentals

Cottage (2 Bedrooms) | Interior

Lake Access & Boat Slip: Greenwood Cottage!

Lake Access & Boat Slip: Greenwood Cottage!
3.0 star property
Greenwood
10.0 out of 10, Exceptional, (1 review)
"Outstanding little cottage for my mom and daughter weekend! Super clean and comfortable. "
United States
Gina
$358 nightly
The price is $397
Jun 17 - Jun 18
Total with taxes and fees
Lake Access & Boat Slip: Greenwood Cottage!
Dining

Country living lake style near Santee

Country living lake style near Santee
Summerton
10.0 out of 10, Exceptional, (46 reviews)
"Clean, private, well maintained. Adequate parking for boaters. Excellent location for lake bound vacationers. Host very responsive."
United States
Jeffrey
$190 nightly
The price is $211
Jun 17 - Jun 18
Total with taxes and fees
Country living lake style near Santee
Smart TV, books

Peaceful Farm Getaway

Peaceful Farm Getaway
Mullins
10.0 out of 10, Exceptional, (36 reviews)
"Awesome location near family for the holiday. I can’t wait to book again "
United States
sheliars1 ..
$195 nightly
The price is $213
Jun 17 - Jun 18
Total with taxes and fees
Peaceful Farm Getaway
Property grounds

The Perfect Home Base to Explore The Carolinas, See Family, or Find Quiet

The Perfect Home Base to Explore The Carolinas, See Family, or Find Quiet
Bennettsville
9.8 out of 10, Exceptional, (28 reviews)
"Far from the Madding Crowd, this farm property is hidden in a field surrounded by trees. Very quiet."
United States
Anand
$76 nightly
The price is $85
Jun 21 - Jun 22
Total with taxes and fees
The Perfect Home Base to Explore The Carolinas, See Family, or Find Quiet
Interior

Walking distance from one of South Carolina's top Medical centers.

Walking distance from one of South Carolina's top Medical centers.
Florence
9.8 out of 10, Exceptional, (53 reviews)
"Our third time staying at this home and always have had a great experience. Such a comfy home and very well stocked. Great hosts!"
United States
Kelly W.
$205 nightly
The price is $230
Jun 17 - Jun 18
Total with taxes and fees
Walking distance from one of South Carolina's top Medical centers.
Exterior

StudioRes by Marriott Columbia Harbison

StudioRes by Marriott Columbia Harbison
2.5 star property
Columbia
6.0 out of 10, (3 reviews)
"My family and I stayed here for one night. It was more than accommodating. However, if I wanted to stay longer, I wouldn't chose this location. The staff was friendly and the place is very clean."
United States
NYTTA
$85 nightly
The price is $95
Jun 25 - Jun 26
Total with taxes and fees
StudioRes by Marriott Columbia Harbison
1 bedroom, iron/ironing board, travel crib, free WiFi

Charming Cottage with easy access to local attractions-pet and kid friendly

Charming Cottage with easy access to local attractions-pet and kid friendly
Sellers
9.6 out of 10, Exceptional, (27 reviews)
"A great place to stay with our two dogs. We will be back again soon."
United States
Marianne P.
$180 nightly
The price is $196
Jun 17 - Jun 18
Total with taxes and fees
Charming Cottage with easy access to local attractions-pet and kid friendly
Interior

Secret SC Cabin on 100 acres Hot Tub Large Pond

Secret SC Cabin on 100 acres Hot Tub Large Pond
Marion
9.6 out of 10, Exceptional, (184 reviews)
"Great location and house and the host was excellent!"
United States
Josh R.
$432 nightly
The price is $470
Jun 17 - Jun 18
Total with taxes and fees
Secret SC Cabin on 100 acres Hot Tub Large Pond
Microwave, oven, stovetop, dishwasher

Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views

Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views
Hartsville
10.0 out of 10, Exceptional, (12 reviews)
"Very clean, stayed here for work. Would definitely book again if in the area. "
United States
Kacey
$150 nightly
The price is $164
Jul 6 - Jul 7
Total with taxes and fees
Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views
Exterior

Red Fox Farms Guest House

Red Fox Farms Guest House
Lancaster
10.0 out of 10, Exceptional, (28 reviews)
"Host was very nice and the property was very clean and neat. Very quiet and peaceful."
United States
Bailey
$242 nightly
The price is $271
Jun 17 - Jun 18
Total with taxes and fees
Red Fox Farms Guest House
Dining

Waterfront Cottage, Fiery Sunsets

Waterfront Cottage, Fiery Sunsets
Steele Creek
10.0 out of 10, Exceptional, (45 reviews)
"Lake side cabin with a pontoon. Great location, very quiet with birdsong. Some deer wandered past on our last morning. All the amenities you need to stay comfortably and short drive to shops for groceries. With large suitcases stairs could be an issue but we managed fine. Very good washer and drier if you are mid trip! Great hosts!"
Australia
Daniel
$423 nightly
The price is $488
Jun 30 - Jul 1
Total with taxes and fees
Waterfront Cottage, Fiery Sunsets
Sauna

Horizons Sandhills

Horizons Sandhills
3.5 star property
Patrick
$413 nightly
The price is $450
Jul 12 - Jul 13
Total with taxes and fees
Horizons Sandhills
Exterior

Casey's Cottage- Georgia Ave

Casey's Cottage- Georgia Ave
North Augusta
9.4 out of 10, Exceptional, (27 reviews)
"Our host was amazing! Always available and so very helpful!"
United States
Gloria G.
$97 nightly
The price is $108
Jun 29 - Jun 30
Total with taxes and fees
Casey's Cottage- Georgia Ave
House (3 Bedrooms) | Interior

3 Mi to Marina: Quiet Getaway w/ Deck in Lexington

3 Mi to Marina: Quiet Getaway w/ Deck in Lexington
3.0 star property
Lexington
10.0 out of 10, Exceptional, (1 review)
"Very cozy home lots of room and kept clean!"
United States
Noah
$430 nightly
The price is $478
Jun 28 - Jun 29
Total with taxes and fees
3 Mi to Marina: Quiet Getaway w/ Deck in Lexington
Outdoor dining

Cozy Camping Cabin on Lake Marion near Congaree Nat Park

Cozy Camping Cabin on Lake Marion near Congaree Nat Park
Rimini
8.4 out of 10, Very Good, (16 reviews)
"Great place to stay. "
United States
Scott J.
$120 nightly
The price is $133
Jun 17 - Jun 18
Total with taxes and fees
Cozy Camping Cabin on Lake Marion near Congaree Nat Park
Smart TV

The Turquoise Door in Town of Lexington

The Turquoise Door in Town of Lexington
Lexington
9.8 out of 10, Exceptional, (130 reviews)
"Very clean and it worked perfectly for our party of 3. My 93 yr old mom Can’t do stairs anymore so this was perfect! Walter was quick at communicating back to any questions or concerns that I had. Would def stay here again!"
United States
Jualetha
$271 nightly
The price is $301
Jun 22 - Jun 23
Total with taxes and fees
The Turquoise Door in Town of Lexington
1 bedroom, free WiFi, bed sheets

Charlotte Glamping Dome- Fawn and Fern Hideaway

Charlotte Glamping Dome- Fawn and Fern Hideaway
Charlotte
10.0 out of 10, Exceptional, (50 reviews)
"We had a great stay! Great views, comfortable accommodations and a seamless check in."
United States
Aaron M.
$260 nightly
The price is $299
Jun 17 - Jun 18
Total with taxes and fees
Charlotte Glamping Dome- Fawn and Fern Hideaway
Fridge, microwave, oven, stovetop

Camden Cottage

Camden Cottage
Camden
10.0 out of 10, Exceptional, (63 reviews)
"The location really is the highlight and the bed is excellent. "
United States
Paul C.
$164 nightly
The price is $183
Jun 23 - Jun 24
Total with taxes and fees
Camden Cottage
Interior detail

The Hangar Lofts Hotel

The Hangar Lofts Hotel
2.5 star property
Rosewood
8.6 out of 10, Excellent, (81 reviews)
"Very nice place "
United States
Steven
$163 nightly
The price is $183
Jun 21 - Jun 22
Total with taxes and fees
The Hangar Lofts Hotel
Exterior

The Uptown - King Suite on Abbeville's Historic Square

The Uptown - King Suite on Abbeville's Historic Square
Abbeville
10.0 out of 10, Exceptional, (12 reviews)
"Such an awesome stay at the Loft! The space was incredible and beautiful!"
United States
Penny B.
$204 nightly
The price is $220
Jun 17 - Jun 18
Total with taxes and fees
The Uptown - King Suite on Abbeville's Historic Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South Carolina Midlands Hotel Reviews

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

10/10 Excellent
"everything was great, really nice hotel"
Tali 1-night trip
Posted 5 hours ago
Spark by Hilton Florence North I-95, SC

Find out more about South Carolina Midlands

Everything you need to know about South Carolina Midlands vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the South Carolina Midlands vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect South Carolina Midlands vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

South Carolina Midlands vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in South Carolina Midlands. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit South Carolina Midlands in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $95 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on South Carolina Midlands rentals

At Expedia, we put the best South Carolina Midlands vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top South Carolina Midlands rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream South Carolina Midlands vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around South Carolina Midlands. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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