South Carolina Midlands Vacation Rentals

Start date: Check-in selected.
To Date
End date: Check-out

Check prices for these dates

In two weeks
Dec 26 - Dec 28
In two months
Feb 6 - Feb 8
In three months
Mar 6 - Mar 8
In four months
Apr 3 - Apr 5

Vacation Rentals in South Carolina Midlands

Land view from property
Long Cove Resort near Charlotte Airport

Cabin in Steele Creek

3.0 star property
8.6 out of 10, Excellent, (231)
"Beautiful beach"
United States
Cassie
$160 nightly
The price is $175
Dec 10 - Dec 11
Total with taxes and fees
Long Cove Resort near Charlotte Airport
Exterior
Carowinds Camp Wilderness

Cabin in Charlotte

3.0 star property
8.8 out of 10, Excellent, (34)
"Cleanest place to stay we have ever had Staff was friendly and efficient Area is conveniently located near grocery store Aldis, and several restaraunt choices However, lots of noise from near by airport "
United States
Kaleb
$172 nightly
The price is $198
Dec 10 - Dec 11
Total with taxes and fees
Carowinds Camp Wilderness
Interior detail
The Hangar Lofts Hotel

Aparthotel in Rosewood

2.5 star property
8.6 out of 10, Excellent, (73)
"Great place! Clean and spacious. The owner was very welcoming and friendly. He made the experience very pleasant. "
United States
Matt
$153 nightly
The price is $172
Dec 11 - Dec 12
Total with taxes and fees
The Hangar Lofts Hotel
Fridge, microwave, oven, stovetop
Peaceful Farm Getaway

Vacation Home in Mullins

10.0 out of 10, Exceptional, (31)
"The property is fantastic and so are the owners. Do not hesitate to book this property.!"
United States
Teddy R.
$194 nightly
The price is $211
Dec 10 - Dec 11
Total with taxes and fees
Peaceful Farm Getaway
House | 4 bedrooms
Hot Tub BBQ Retreat Spacious Backyard Pet-friendly

Vacation Home in North Augusta

2.0 star property
10.0 out of 10, Exceptional, (1)
"The house was So Cozy! Perfect space for the family from near and far to gather for Thanksgiving dinner. The neighborhood was quiet and felt very safe! Would definitely stay there again if needed. Definitely recommend for an overnight stay or weeks to months. Very Satisfied!!"
United States
carmen
$561 nightly
The price is $630
Dec 10 - Dec 11
Total with taxes and fees
Hot Tub BBQ Retreat Spacious Backyard Pet-friendly
Fridge, microwave, stovetop, coffee/tea maker
Charming Cottage with easy access to local attractions-pet and kid friendly

Cottage in Sellers

9.2 out of 10, Wonderful, (15)
"Great property."
United States
Marci
$182 nightly
The price is $198
Dec 10 - Dec 11
Total with taxes and fees
Charming Cottage with easy access to local attractions-pet and kid friendly
Property grounds
Cozy Off Grid Cabin w/pond for fishing.

Cabin in Greenwood

10.0 out of 10, Exceptional, (5)
"Peace and quiet! James was so thoughtful and nice. The cabin is Off-grid but doesn't feel like it's lacking anything. Well thought out property with everything you need included.Solar lighting in all the spaces as well as an included battery pack for phone charging etc. Was a perfect stay for going to Diamond Hill mine. "
United States
Shannon H.
$108 nightly
The price is $119
Dec 10 - Dec 11
Total with taxes and fees
Cozy Off Grid Cabin w/pond for fishing.
Terrace/patio
Victory Reins- Quiet Country Stay Near Aiken, Pet Friendly + Parking

Vacation Home in Wagener

10.0 out of 10, Exceptional, (15)
"This is an incredible property!! Would love to come back…super comfy, super clean, very well appointed! "
United States
Marissa R.
$367 nightly
The price is $411
Dec 12 - Dec 13
Total with taxes and fees
Victory Reins- Quiet Country Stay Near Aiken, Pet Friendly + Parking
Fridge, microwave, oven, stovetop
Cozy Party House in the woods

Vacation Home in Waxhaw

2.0 star property
8.6 out of 10, Excellent, (7)
"Clean, roomy, quiet… lovely for our weekend getaway to quaint little town with so much to offer!"
United States
Cara G.
$366 nightly
The price is $393
Dec 21 - Dec 22
Total with taxes and fees
Cozy Party House in the woods
Interior
Secret SC Cabin on 100 acres Hot Tub Large Pond

Cabin in Marion

9.6 out of 10, Exceptional, (174)
"We WILL be back to this cute little cabin! It had everything. Only thing better would be more fish in the pond lol thanks for having us!"
United States
Kimberly L.
$430 nightly
The price is $468
Dec 10 - Dec 11
Total with taxes and fees
Secret SC Cabin on 100 acres Hot Tub Large Pond
Fridge, microwave, oven, stovetop
Walking distance from one of South Carolina's top Medical centers.

Vacation Home in Florence

9.8 out of 10, Exceptional, (42)
"The house was beautiful. We would stay there again!!"
United States
Stephanie L.
$206 nightly
The price is $231
Dec 11 - Dec 12
Total with taxes and fees
Walking distance from one of South Carolina's top Medical centers.
Property grounds
The Perfect Home Base to Explore The Carolinas, See Family, or Find Quiet

Apartment in Bennettsville

9.8 out of 10, Exceptional, (18)
"This was a perfect spot for us for the night. The drive there was pleasant, the location quiet. We would return."
United States
Kirsten K.
$76 nightly
The price is $85
Dec 11 - Dec 12
Total with taxes and fees
The Perfect Home Base to Explore The Carolinas, See Family, or Find Quiet
1 bedroom, free WiFi, bed sheets
1972 Airstream luxury tiny living at it's best in Columbia near Lake Murray!

Vacation Home in Columbia

2.0 star property
9.8 out of 10, Exceptional, (26)
"We enjoy our stay at this quaint quiet place. Loved the outdoor sitting area and the airstream was clean an cutely decorated."
United States
Marian A.
$147 nightly
The price is $159
Dec 11 - Dec 12
Total with taxes and fees
1972 Airstream luxury tiny living at it's best in Columbia near Lake Murray!
Fridge, microwave, oven, stovetop
Charming cottage in great neighborhood...close to downtown, fort and university

Cottage in Columbia

9.8 out of 10, Exceptional, (34)
"Would stay there again and again! "
United States
Paige I.
$231 nightly
The price is $259
Dec 14 - Dec 15
Total with taxes and fees
Charming cottage in great neighborhood...close to downtown, fort and university
Terrace/patio
Casey's Cottage- Georgia Ave

Cottage in North Augusta

9.4 out of 10, Exceptional, (14)
"Zero issues, super easy check in process. House was clean and had no issues. Would stay again. "
United States
Kenneth W.
Casey's Cottage- Georgia Ave
Microwave, oven, stovetop, dishwasher
Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views

Apartment in Hartsville

10.0 out of 10, Exceptional, (4)
"Sooo good. Peaceful country setting yet close to everything. We will definitely try staying here again next time."
United States
Randy W.
$145 nightly
The price is $158
Jan 5 - Jan 6, 2026
Total with taxes and fees
Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views
Terrace/patio
stayAPT Suites Columbia-Irmo Harbison

Aparthotel in Irmo

2.5 star property
8.6 out of 10, Excellent, (327)
"Great stay. "
United States
Ty
$107 nightly
The price is $117
Dec 11 - Dec 12
Total with taxes and fees
stayAPT Suites Columbia-Irmo Harbison
2 bedrooms, desk, iron/ironing board, travel crib
Double King 2bed/2 bath in Downtown Columbia!

Vacation Home in Columbia

2.0 star property
9.8 out of 10, Exceptional, (7)
"Clean, quaint, updated kitchen and easy access to the main drag. "
United States
John W.
$358 nightly
The price is $392
Dec 10 - Dec 11
Total with taxes and fees
Double King 2bed/2 bath in Downtown Columbia!
Interior
stayAPT Suites Rock Hill

Aparthotel in Rock Hill

2.5 star property
8.4 out of 10, Very Good, (196)
"Clean and staff was very friendly. "
United States
Cydney
$95 nightly
The price is $105
Dec 11 - Dec 12
Total with taxes and fees
stayAPT Suites Rock Hill
Fridge, microwave, oven, stovetop
Lake Carolina Coach Cottage/Amazing stay/Columbia,S.C.

Cottage in Lake Carolina

9.6 out of 10, Exceptional, (14)
"Very nice property and neighborhood."
United States
Neal P.
$288 nightly
The price is $323
Jan 5 - Jan 6, 2026
Total with taxes and fees
Lake Carolina Coach Cottage/Amazing stay/Columbia,S.C.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top South Carolina Midlands Hotel Reviews

Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown

10/10 Excellent
"Staff were nice & professional. Facility was very clean and every area smelled fresh and inviting. I didn't eat breakfast but it smelled amazing. Just know there are extra per day parking fees."
Qiana 3-night trip
Posted 16 hours ago
Tru By Hilton Columbia Downtown

Find out more about South Carolina Midlands

Everything you need to know about South Carolina Midlands vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the South Carolina Midlands vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect South Carolina Midlands vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

South Carolina Midlands vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in South Carolina Midlands. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit South Carolina Midlands in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $105 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on South Carolina Midlands rentals

At Expedia, we put the best South Carolina Midlands vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top South Carolina Midlands rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream South Carolina Midlands vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around South Carolina Midlands. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia